摘要:
The use of oxidatively transformed carotenoid or a component thereof to enhance the immune response in a subject for the treatment of infection or to enhance the immune response to an antigen in a subject being immunized. Also disclosed are pharmaceutical compositions and kits containing the oxidatively transformed carotenoid.
摘要:
The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumor cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.
摘要:
Described are cross-specific antibody molecules with binding specificity for both AREG and HBEGF. The antibody molecules may be used in methods of treatment of cancer and diseases associated with angiogenesis.
摘要:
There is provided a method for suppressing a pro-inflammatory immune response in a cell, comprising providing to a cell sialic acid or analogs thereof, wherein the sialic acid or analogs are presented by a substrate such that a pro-inflammatory immune response in a cell is suppressed or an anti-inflammatory immune response is increased in a cell. Further, there is provided a method of treatment of inflammatory disease in a subject in need thereof. There is also provided a drug delivery device and a biomaterial which can modulate the inflammatory response in a subject.
摘要:
Audio in an audio conference is spatialized using either virtual sound-source positioning or sound-field capture. A spatial audio conference is provided between a local and remote parties using audio conferencing devices (ACDs) interconnected by a network. Each ACD captures spatial audio information from the local party, generates either one, or three or more, audio data streams which include the captured information, and transmits the generated stream(s) to each remote party. Each ACD also receives the generated audio data stream(s) transmitted from each of the remote parties, processes the received streams to generate a plurality of audio signals, and renders the signals to produce a sound-field that is perceived by the local party, where the sound-field includes the spatial audio information captured from the remote parties. A sound-field capture device is also provided which includes at least three directional microphones symmetrically configured about a center axis in a semicircular array.
摘要:
The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumour cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.
摘要:
The invention relates to linear polyamino- and/or polyammonium-polysiloxane copolymers, particularly hydrophilic polyquaternary polysiloxane copolymers, and to their use in cosmetic formulations, in laundry detergents or for surface-treating substrates.
摘要:
The invention relates to an image receiving element comprising in order a support, at least one polyolefin resin coating and at least one toner receiver layer, wherein said toner receiver layer comprises a fuser-oil sorbent additive and a thermoplastic polymer and said additive is present in an amount of greater than 10% by weight of said layer.
摘要:
Aldehyde scavengers which are adducts of choline or a choline salt and an optionally substituted acrylamide monomer can be used to stabilize glyoxalated polyacrylamide compositions and to provide supplementary cationic charges for the polymer backbone.
摘要:
An oxidation process is described which involves subjecting a feedstock which contains oxidisable material to temperature, pressure and contact with an oxidant. Excess water and volatile oxidation products, such as carbon dioxide, formic acid and acetic acid, are removed in the vapour phase. A catalyst may be employed to increase the rate of reaction. Preferred catalysts include the transition metal ions. Advantageously, the process may be operated in a continuous manner wherein the feedstock is continuously introduced into a reactor and a vapour phase containing volatile oxidation products continuously removed. The process is particularly applicable to the treatment of consumer and industrial waste.