公开(公告)号：US20150119572A1

公开(公告)日：2015-04-30

申请号：US14365822

申请日：2012-12-20

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Michael Rack ,  Michael Keil ,  Bernd Wolf ,  Uwe Josef Vogelbacher ,  Joachim Gebhardt ,  Timo Frassetto ,  Volker Maywald

IPC: C07C231/24 ,  C07C235/34 ,  C07D207/16 ,  C07C231/12

CPC classification number: C07C231/24 ,  C07C231/12 ,  C07C235/20 ,  C07C235/34 ,  C07D207/06 ,  C07D207/16 ,  C07D211/16 ,  C07D295/185 ,  C07D413/04

Abstract: The present invention relates to a process for manufacturing aryloxyacetamides of formula (I), by reacting haloacetamides of formula (II) with a phenol of formula (III); wherein the variables are defined according to the description, and aryloxyacetamides of formula (I).

Abstract translation: 本发明涉及通过使式（II）的卤代乙酰胺与式（III）的苯酚反应制备式（I）的芳氧基乙酰胺的方法; 其中所述变量根据描述定义，和式（I）的芳氧基乙酰胺。

公开(公告)号：US11613549B2

公开(公告)日：2023-03-28

申请号：US16960192

申请日：2019-01-14

Applicant: BASF SE

Inventor： Michael Rack ,  Bernd Mueller

IPC: C07D213/61 ,  C07F1/02 ,  C07D217/26 ,  C07D401/04

Abstract: The present invention relates to a process for the preparation pyridine derivatives of the formula (I).

公开(公告)号：US11046656B2

公开(公告)日：2021-06-29

申请号：US16731289

申请日：2019-12-31

Applicant: BASF SE

Inventor： Eric George Klauber ,  Michael Rack ,  Roland Goetz ,  Sebastian Soergel

IPC: C07D237/12 ,  C07D237/20 ,  C07D401/12 ,  C07B31/00 ,  C07B39/00 ,  C07B43/04 ,  C07D403/12

Abstract: Provided herein is a process for preparing a pyridazine amine compound of formula V, and a process for preparing dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof. Further, provided herein are novel dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof, wherein the amino group is an ethylamino group.

公开(公告)号：US11021452B2

公开(公告)日：2021-06-01

申请号：US16634202

申请日：2018-07-21

Applicant: BASF SE

Inventor： Christopher Koradin ,  Wassilios Grammenos ,  Michael Rack ,  Kailaskumar Borate ,  Roland Goetz

IPC: C07D271/06

Abstract: The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles (compounds I), which can be obtained through reaction of hydroxyamidine compounds of formula II with trifluoroacetyl halides IIa.

公开(公告)号：US10087133B2

公开(公告)日：2018-10-02

申请号：US15102353

申请日：2014-12-10

Applicant: BASF SE

Inventor： Eric George Klauber ,  Michael Rack ,  Thomas Zierke ,  Nicole Holub ,  David Cortes ,  Gerald Schmelebeck ,  Junmin Ji

IPC: C07C51/367 ,  C07C67/31 ,  C07C45/64 ,  C07C253/30 ,  C07C51/08

Abstract: The present invention relates to a process for providing dihalogen substituted salicylic acid derivatives of formula (II):

公开(公告)号：US09957212B2

公开(公告)日：2018-05-01

申请号：US15119654

申请日：2015-02-19

Applicant: BASF SE

Inventor： Eric George Klauber ,  Michael Rack ,  Thomas Zierke ,  Nicole Holub ,  Gerald Schmelebeck ,  Junmin Ji ,  David Cortes

IPC: C07C37/02 ,  C07C41/16 ,  C07C37/62 ,  C07C51/16 ,  C07C51/285

CPC classification number: C07C41/16 ,  C07C37/02 ,  C07C37/62 ,  C07C51/16 ,  C07C51/285 ,  C07C65/21 ,  C07C43/225 ,  C07C39/30 ,  C07C39/28

Abstract: The present invention relates to a process for providing a compound of formula (IV): wherein R1 and R2 are each independently C1-C4 alkyl, and Hal is independently Cl or Br, the process comprising the steps of: (i) reacting a compound of formula (II) wherein R1 and Hal is defined as above, to obtain a compound of formula (III) wherein R1 and Hal is defined as above, and (ii) reacting the compound of formula (III) to obtain the compound of formula (IV).

公开(公告)号：US09701604B2

公开(公告)日：2017-07-11

申请号：US15101080

申请日：2014-12-01

Applicant: BASF SE

Inventor： Eric George Klauber ,  Michael Rack ,  Thomas Zierke ,  Sebastian Wloch ,  Nicole Holub ,  Stefan Dudenhoeffer ,  Gerald Schmelebeck ,  Junmin Ji ,  David Cortes

IPC: C07C37/70 ,  C07C37/84 ,  C07C37/74

CPC classification number: C07C37/74 ,  C07C37/84 ,  C07C39/30

Abstract: A process for purifying 2,5-dichlorophenol, the process comprising the steps of distillation and subsequent crystallization.

公开(公告)号：US09556141B2

公开(公告)日：2017-01-31

申请号：US14359446

申请日：2012-11-20

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frassetto ,  Gemma Veitch

IPC: C07D401/14 ,  C07D471/10 ,  C07D401/04

CPC classification number: C07D401/04 ,  C07D471/10

Abstract: The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carboxylate compound of the formula (I-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (I-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I)

Abstract translation: 本发明涉及制备式（IA）的N-取代的1H-吡唑-5-羧酸酯化合物的方法，包括以下步骤：i）将式（II）的化合物去质子化，其中变量R1，R2和 r各自如说明书和权利要求中所定义，其中镁 - 有机碱具有碳结合的镁; 和ii）通过使步骤（i）中获得的产物与选自二氧化碳或二氧化碳当量的试剂反应来进行羰基化，得到式（I-A）化合物; 并且涉及进一步转化得到式（I）的N-取代的1H-吡唑-5-碳酰氯化合物，

公开(公告)号：US09518045B2

公开(公告)日：2016-12-13

申请号：US14421351

申请日：2013-08-09

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Goetz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07D413/04 ,  C07D265/36 ,  C07C335/28

CPC classification number: C07D413/04 ,  C07C335/28 ,  C07D265/36

Abstract: The present invention relates to a process for manufacturing benzoxazinones of formula (I), wherein the variables are defined according to the description, by reacting carbamates of formula (II) are reacted with carbamat-benzoxazinones of formula (III) in the presence of a base.

公开(公告)号：US09409894B2

公开(公告)日：2016-08-09

申请号：US14421321

申请日：2013-07-29

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Roland Götz ,  Joachim Gebhardt ,  Uwe Josef Vogelbacher ,  Timo Frassetto ,  Michael Rack ,  Volker Maywald ,  Bernd Wolf

IPC: C07C335/28 ,  C07C275/60 ,  C07D265/36 ,  C07D413/04

CPC classification number: C07D413/04 ,  C07C275/60 ,  C07C335/28 ,  C07D265/36

Abstract: The present invention relates to carbamates of formula (I), wherein the variables are defined according to the description, as well as to a process for manufacturing carbamates of formula (I), and to the use of carbamates of formula (I) in manufacturing benzoxazinones of formula (VII).

Abstract translation: 本发明涉及式（I）的氨基甲酸酯，其中根据描述定义变量，以及制备式（I）的氨基甲酸酯的方法，以及式（I）的氨基甲酸酯在制造中的用途 式（VII）的苯并恶嗪酮。