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公开(公告)号：US20210046236A1
公开(公告)日：2021-02-18
申请号：US17076152
申请日：2020-10-21
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Ying-Cheng Lo , Aaron W. Brown , Yuanpang Samuel Ding , leng Kin Lao , Zachariah Louis Fuller , Aaron Joseph Geier , Alan John Harvey , Leansu Kiatoukaysy Lo
Abstract: A gravity fed peritoneal dialysis (“PD”) machine includes: a frame configured to be set on a supporting surface; at least one load cell; a scale platform supported by the frame via the at least one load cell positioned between the frame and the scale platform; a drain container support in mechanical communication with and extending downwardly from the scale platform, the machine configured such that when the frame is set on the supporting surface, at least one fresh PD fluid supply container is supportable by the scale platform above the at least one load cell and at least one used PD fluid drain container is supportable by the drain container support below the at least one load cell, so that a combined weight of fresh PD fluid and used PD fluid may be sensed by the at least one load cell.
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公开(公告)号：US20200214938A1
公开(公告)日：2020-07-09
申请号：US16630994
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Yuanpang Samuel Ding , Ying-Cheng Lo , Jacob Daniel Rivett , Grant Anthony Bomgaars , Thomas Edward Dudar , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Joseph Vincent Ranalletta , Bernd Krause
Abstract: A system for reconstituting and sterilizing a concentrate includes a mixing container, a filtration device, and a product bag. The a mixing container has an inlet port and outlet port in fluid communication with a mixing chamber disposed between the inlet port and the outlet port. The mixing chamber is adapted to contain a product concentrate. The filtration device has an inlet and an outlet, the inlet of the filtration device coupled to the outlet port of the mixing container. The filtration device includes a filter membrane with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm. The product bag has an inlet port coupled to the outlet of the filtration device, and has a bladder defining an empty sterile chamber for receiving sterilized and reconstituted product resulting from mixing a diluent with a product concentrate in the mixing chamber to obtain a mixture then introduced through the filtration device to obtain the reconstituted and sterilized product.
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公开(公告)号：US20200147310A1
公开(公告)日：2020-05-14
申请号：US16631051
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Yuanpang Samuel Ding , Marc Steven Minkus , Ying-Cheng Lo , Mark Joseph. Doty , Thomas Edward Dudar , Grant Anthony Bomgaars , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Bernd Krause , Joseph Vincent Ranalletta
Abstract: A syringe system includes a syringe and a filtration device connected to the syringe for sterilizing and introducing fluid into the syringe. The syringe includes a syringe barrel having a proximal end defining a barrel opening, a distal end defining a delivery opening, a bore extending between the proximal end and the distal end, and a stopper disposed in the bore of the syringe barrel. The filtration device has an inlet and an outlet coupled in fluid communication with the delivery opening at the distal end of the syringe barrel. The filtration device includes a stem and a filter membrane disposed in line with the stem. The filter membrane optionally has a plurality of pores each with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm such that a pharmaceutical fluid can be introduced as a sterilized pharmaceutical fluid into the bore of the syringe barrel by passing through the filtration device.
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公开(公告)号：US20200147251A1
公开(公告)日：2020-05-14
申请号：US16631067
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： William Spencer Hurst , Steven Clarence Jepson , Grant Anthony Bomgaars , Yuanpang Samuel Ding , Thomas Edward Dudar , Ying-Cheng Lo , Bernd Krause , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Joseph Vincent Ranalletta
Abstract: A product bag includes a bladder and an elongated filtration device. The bladder includes opposing first and second film layers defining a product chamber. The first and second film layers are sealed together along a perimeter seal extending along at least a portion of a perimeter of the bladder. The elongated filtration device includes a housing, a filtration membrane disposed in the housing, an inlet adapted for receiving a fluid to be filtered, and an outlet in fluid communication with the product chamber. A majority of the elongated filtration device is embedded between the first and second film layers of the perimeter seal of the bladder to provide for a compact form factor.
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公开(公告)号：US10463776B2
公开(公告)日：2019-11-05
申请号：US15265058
申请日：2016-09-14
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
Abstract: Methods and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea, a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid, and a urea removal unit configured to remove at least a portion of the urea from the secondary fluid and return the secondary fluid to the urea separation unit. In an embodiment, the urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber, the membrane including at least one of: (i) a positive charge to prevent positive ions from transporting across the membrane; and (ii) a negative charge to prevent negative ions from transporting across the membrane.
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Patent Agency Ranking
公开(公告)号：US10406270B2
公开(公告)日：2019-09-10
申请号：US15074457
申请日：2016-03-18
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a combination electrodialysis and urea oxidation cell.
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公开(公告)号：US20190021947A1
公开(公告)日：2019-01-24
申请号：US16070009
申请日：2017-01-20
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Grant Anthony Bomgaars , Bernd Krause , Mark Edward Pasmore , Michael Joseph Sadowski , Yuanpang Samuel Ding , Ying-Cheng Lo , Joseph Vincent
Abstract: A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.
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公开(公告)号：US20170189599A1
公开(公告)日：2017-07-06
申请号：US15265058
申请日：2016-09-14
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
CPC classification number: A61M1/1696 , A61M1/1603 , A61M1/267 , A61M1/282 , A61M1/3472
Abstract: Methods and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea, a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid, and a urea removal unit configured to remove at least a portion of the urea from the secondary fluid and return the secondary fluid to the urea separation unit. In an embodiment, the urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber, the membrane including at least one of: (i) a positive charge to prevent positive ions from transporting across the membrane; and (ii) a negative charge to prevent negative ions from transporting across the membrane.
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39.发明申请公开(公告)号：US20170189595A1
公开(公告)日：2017-07-06
申请号：US15074457
申请日：2016-03-18
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
CPC classification number: A61M1/169 , A61M1/1696 , B01D61/445 , B01D61/46 , B01D61/48 , C02F1/4693 , C02F2101/16 , C25F1/00 , C25F7/00
Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a combination electrodialysis and urea oxidation cell.
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公开(公告)号：US11974966B2
公开(公告)日：2024-05-07
申请号：US16631030
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： David Filiberto Schuck , Karl Hans Cazzini , Yuanpang Samuel Ding , Ying-Cheng Lo , Grant Anthony Bomgaars , Thomas Edward Dudar , Mark Edward Pasmore , Bernd Krause , Michael Joseph Sadowski , Anastasios Hristakos , Joseph Vincent Ranalletta
CPC classification number: A61J1/1456 , A61J1/10 , A61J1/1475 , A61J1/2024 , A61J1/2093 , B01D63/0241
Abstract: A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.
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