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公开(公告)号：US08608758B2
公开(公告)日：2013-12-17
申请号：US12722134
申请日：2010-03-11
Applicant: Wamis Singhatat , Jamie Manos , Brian Rick Delamarter , Dominique Messerli , Brian Schmidt , William Miller , James Talbot , Garland Fussel , Nigel G. Smith
Inventor： Wamis Singhatat , Jamie Manos , Brian Rick Delamarter , Dominique Messerli , Brian Schmidt , William Miller , James Talbot , Garland Fussel , Nigel G. Smith
CPC classification number: A61B17/0485 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/0477 , A61B2017/06052
Abstract: A soft tissue defect repair system for approximating defects, such as defects in the annulus fibrosus of an intervertebral disc, includes a cannulated rod through which is disposed a suture retrieval device. A strand of suture includes a locking or ratcheting knot pre-tied around the outside of the cannulated rod and a free end that is guided in and out of the soft tissue. A knot pusher fits around the cannulated rod, which is used to push the knot off of the cannulated rod after the stitching of the tissue is accomplished. The defect is approximated by tensioning the free end. Various suturing methods or patterns are disclosed for defect approximation.
Abstract translation: 用于近似缺陷的软组织缺损修复系统，例如椎间盘纤维环中的缺陷，包括插管杆，通过该插管杆设置缝合线取出装置。 一股缝合线包括预先束缚在插管杆的外侧的锁定或棘轮结，以及引导进出软组织的自由端。 一个结推动器围绕插管杆，用于在组织的缝合完成之后将结从推杆上推出。 通过张紧自由端近似缺陷。 公开了各种缝合方法或图案用于缺陷近似。
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32.发明申请DETERGENT COMPOSITIONS CONTAINING GEOBACILLUS STEAROTHERMOPHILUS LIPASE AND METHODS OF USE THEREOF 失效含有GEOBACILLUS STEAROTHERMOPHILUS LIPASE的洗涤剂组合物及其使用方法公开(公告)号：US20120309063A1
公开(公告)日：2012-12-06
申请号：US13518354
申请日：2010-12-14
Applicant: Christian Adams , Brian Schmidt
Inventor： Christian Adams , Brian Schmidt
CPC classification number: C11D3/38627 , C12N9/20
Abstract: The present compositions and methods relate to a lipase cloned from Geobacillus stearothermophilus, polynucleotides encoding the lipase, and methods of use thereof. The compositions and methods have particular application in detergent cleaning compositions and methods.
Abstract translation: 本发明的组合物和方法涉及从嗜热脂肪芽孢杆菌克隆的脂肪酶，编码脂肪酶的多核苷酸及其使用方法。 组合物和方法在洗涤剂清洁组合物和方法中具有特别的应用。
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33.发明申请DETERGENT COMPOSITIONS CONTAINING BACILLUS SUBTILIS LIPASE AND METHODS OF USE THEREOF 审中-公开含有BACILLUS SUBTILIS LIPASE的洗涤剂组合物及其使用方法公开(公告)号：US20120258900A1
公开(公告)日：2012-10-11
申请号：US13518351
申请日：2010-12-16
Applicant: Christian Adams , Brian Schmidt
Inventor： Christian Adams , Brian Schmidt
IPC: C11D3/386
CPC classification number: C11D3/38627 , C07K2319/20 , C12N9/20 , C12N9/2437 , C12Y302/01004
Abstract: The present compositions and methods relate to a lipase cloned from Bacillus subtilis, polynucleotides encoding the lipase, and methods of use thereof. The compositions and methods have particular application in detergent cleaning compositions and methods.
Abstract translation: 本发明的组合物和方法涉及从枯草芽孢杆菌克隆的脂肪酶，编码脂肪酶的多核苷酸及其使用方法。 组合物和方法在洗涤剂清洁组合物和方法中具有特别的应用。
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34.发明授权公开(公告)号：US08142727B2
公开(公告)日：2012-03-27
申请号：US12331149
申请日：2008-12-09
Applicant: Brian Schmidt , Bradley Ginger
Inventor： Brian Schmidt , Bradley Ginger
CPC classification number: F26B23/022 , Y02P70/40
Abstract: A System for reducing organic contaminates from the condensate discharge of a closed loop industrial drying process. The system includes a dryer, a regenerative thermal oxidizer (RTO) in flow communication with the dryer, and an energy recovery unit in flow communication with the RTO.
Abstract translation: 一种用于从闭环工业干燥过程的冷凝物排放中减少有机污染物的系统。 该系统包括与干燥器流体连通的干燥器，再生热氧化器（RTO）以及与RTO流动连通的能量回收单元。
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公开(公告)号：US20120015426A1
公开(公告)日：2012-01-19
申请号：US13246623
申请日：2011-09-27
Applicant: Fredric R. BLOOM , Brian Schmidt
Inventor： Fredric R. BLOOM , Brian Schmidt
IPC: C12N1/20
CPC classification number: C12N15/70
Abstract: Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation).
Abstract translation: 公开了能够用甲基化和/或未甲基化的核酸进行高效转化并且是抗噬菌体的新型细菌宿主。 这种细菌含有：（1）赋予高效转化能力的F'附加体; （2）允许甲基化核酸转化的一个或多个突变; （3）允许用未甲基化核酸转化的一个或多个突变; 和/或（4）赋予抗噬菌体感染的一种或多种突变。 还公开了用于转化这种细菌的方法，以及含有这种细菌的试剂盒（例如已经使其能够转化）。
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Patent Agency Ranking
公开(公告)号：US20100167379A1
公开(公告)日：2010-07-01
申请号：US12646828
申请日：2009-12-23
Applicant: Fredric R. Bloom , Brian Schmidt
Inventor： Fredric R. Bloom , Brian Schmidt
IPC: C12N1/20
CPC classification number: C12N15/70
Abstract: Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation).
Abstract translation: 公开了能够用甲基化和/或未甲基化的核酸进行高效转化并且是抗噬菌体的新型细菌宿主。 这种细菌含有：（1）赋予高效转化能力的F'附加体; （2）允许甲基化核酸转化的一个或多个突变; （3）允许用未甲基化核酸转化的一个或多个突变; 和/或（4）赋予抗噬菌体感染的一种或多种突变。 还公开了用于转化这种细菌的方法，以及含有这种细菌的试剂盒（例如已经使其能够转化）。
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37.发明授权公开(公告)号：US07592157B2
公开(公告)日：2009-09-22
申请号：US11848213
申请日：2007-08-30
Applicant: Hans De Nobel , David A. Estell , Wei Liu , Scott D. Power , Brian Schmidt , Huaming Wang
Inventor： Hans De Nobel , David A. Estell , Wei Liu , Scott D. Power , Brian Schmidt , Huaming Wang
CPC classification number: C12N15/80 , C07K14/811
Abstract: Described herein are protease inhibitors, variants thereof and methods for their production.
Abstract translation: 本文描述的是蛋白酶抑制剂，其变体及其制备方法。
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38.发明授权Bacterial expression of bowman-birk protease inhibitors and variants thereof 有权Bowman-birk蛋白酶抑制剂及其变体的细菌表达公开(公告)号：US07413877B2
公开(公告)日：2008-08-19
申请号：US10984514
申请日：2004-11-08
Applicant: Katherine Collier , Grant Ganshaw , Hans De Nobel , Scott D. Power , Anita Van Kimmenade , Marc Kolkman , Jeffrey Miller , Brian Schmidt , Gudrun Vogtentanz , David Estell
Inventor： Katherine Collier , Grant Ganshaw , Hans De Nobel , Scott D. Power , Anita Van Kimmenade , Marc Kolkman , Jeffrey Miller , Brian Schmidt , Gudrun Vogtentanz , David Estell
CPC classification number: C07K14/81 , A61K38/00 , C07K7/06 , C07K14/811 , C07K2319/00 , C12N15/62
Abstract: The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes for obtaining the Bowman-Birk protease inhibitors.
Abstract translation: 本发明提供了与细菌种中Bowman-Birk蛋白酶抑制剂及其变体的表达相关的组合物和方法。 本发明还提供了融合核酸，载体，融合多肽以及获得Bowman-Birk蛋白酶抑制剂的方法。
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39.发明申请Error detection in physical interfaces for point-to-point communications between integrated circuits 有权集成电路之间点对点通信的物理接口中的错误检测公开(公告)号：US20070260965A1
公开(公告)日：2007-11-08
申请号：US11372866
申请日：2006-03-09
Applicant: Brian Schmidt , Lawrence Butcher
Inventor： Brian Schmidt , Lawrence Butcher
IPC: H04L1/00
CPC classification number: H04L1/0045 , H04L1/0061 , H04L25/4908 , H04L2001/0092
Abstract: An apparatus, system and method for detecting errors in a physical interface during the transmission and/or receipt of data communications between integrated circuits (“ICs”) are disclosed. In one embodiment, an apparatus is configured to operate as or within a receiving physical interface. The apparatus includes a decoder configured to decode a subset of encoded data bits to yield decoded data bits. It also includes a physical interface (“PI”) error detection bit extractor configured to extract a physical interface error detection bit from the decoded data bits. As such, the apparatus uses the physical interface error detection bit to determine whether the encoded data bits include at least one erroneous data bit as an error. In some embodiments, the apparatus includes an error detector configured to operate within a physical layer. In at least one embodiment, the apparatus efficiently transmits error detection codes within, for example, an NB/(N+1)B line coder.
Abstract translation: 公开了在集成电路（“IC”）之间的数据通信传输和/或接收期间检测物理接口中的错误的装置，系统和方法。 在一个实施例中，设备被配置为在接收物理接口内或内部进行操作。 该装置包括解码器，其被配置为解码编码数据位的子集以产生解码的数据位。 它还包括物理接口（“PI”）错误检测位提取器，用于从解码的数据位提取物理接口错误检测位。 这样，该装置使用物理接口错误检测位来确定编码数据位是否包括至少一个错误数据位作为错误。 在一些实施例中，该装置包括被配置为在物理层内操作的错误检测器。 在至少一个实施例中，该装置在例如NB /（N + 1）B线路编码器内有效地发送错误检测码。
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公开(公告)号：US20070118182A1
公开(公告)日：2007-05-24
申请号：US11668109
申请日：2007-01-29
Applicant: Michael O'Phelan , Richard Kavanagh , James Poplett , A. Barr , Brian Schenk , Brian Schmidt
Inventor： Michael O'Phelan , Richard Kavanagh , James Poplett , A. Barr , Brian Schenk , Brian Schmidt
CPC classification number: A61N1/3754 , Y10T29/417 , Y10T29/43
Abstract: A flat capacitor includes a case having a feedthrough hole, a capacitor stack located within the case, a coupling member having a base surface directly attached to the capacitor stack and having a portion extending through the feedthrough hole, the coupling member having a mounting hole, a feedthrough conductor having a portion mounted within the mounting hole, and a sealing member adjacent the feedthrough hole and the feedthrough conductor for sealing the feedthrough hole. Other aspects of the invention include various implantable medical devices, such as pacemakers, defibrillators, and cardioverters, incorporating one or more features of the exemplary feedthrough assembly.
Abstract translation: 扁平电容器包括具有馈通孔的壳体，位于壳体内的电容器叠层，具有直接连接到电容器叠层的基底表面并且具有延伸穿过馈通孔的部分的耦合构件，耦合构件具有安装孔， 馈通导体，其具有安装在安装孔内的部分，以及与馈通孔相邻的密封构件和用于密封馈通孔的馈通导体。 本发明的其它方面包括各种可植入的医疗装置，例如起搏器，除颤器和心律转换器，其结合示例性馈通组件的一个或多个特征。
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