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    Fatty acid treatment
    33.
    发明授权
    Fatty acid treatment 失效
    脂肪酸处理

    公开(公告)号：US5888541A

    公开(公告)日：1999-03-30

    申请号：US784105

    申请日：1997-01-15

    Applicant: David F. Horrobin ,  Brenda E. Reynolds

    Inventor： David F. Horrobin ,  Brenda E. Reynolds

    IPC: A61K31/201 ,  A61K35/78 ,  A61K9/20

    CPC classification number: A61K31/201

    Abstract: Increase gut calcium absorption in humans or animals by the administration of GLA, DGLA or LA as such or in salt or other pharmacologically acceptable form, optionally in association with EPA, DHA or other EFA in similar forms, specifically useful in the treatment of osteoporosis.

    Abstract translation: 通过施用GLA，DGLA或LA本身或以盐或其他药理学上可接受的形式，任选地与EPA，DHA或其他类似形式的EFA相关联地增加对人或动物的肠吸收钙吸收，特别可用于治疗骨质疏松症。

    Treatment of internal radiation damage
    36.
    发明授权
    Treatment of internal radiation damage 失效
    治疗内部辐射损伤

    公开(公告)号：US5583159A

    公开(公告)日：1996-12-10

    申请号：US408135

    申请日：1995-03-21

    Applicant: David F. Horrobin ,  Catherine A. Scott

    Inventor： David F. Horrobin ,  Catherine A. Scott

    IPC: A61K31/20 ,  A61K31/202 ,  A61P25/00 ,  A61P43/00

    CPC classification number: A61K31/202 ,  A61K31/20

    Abstract: Damage to internal tissues, and particularly to the central nervous system as a consequence of exposure to ionizing radiation is prevented or treated by administration of GLA and/or DGLA. Medicaments containing GLA and/or DGLA for such treatment or prevention may also further comprise EPA and/or DHA.

    Abstract translation: 通过施用GLA和/或DGLA来防止或治疗由于暴露于电离辐射而对内部组织，特别是对中枢神经系统的损伤。 含有GLA和/或DGLA用于治疗或预防的药物还可以进一步包含EPA和/或DHA。

    Method for the safe administration of fatty acid
    37.
    发明授权
    Method for the safe administration of fatty acid 失效
    脂肪酸安全施用方法

    公开(公告)号：US5508307A

    公开(公告)日：1996-04-16

    申请号：US378708

    申请日：1995-01-26

    Applicant: David F. Horrobin ,  Catherine A. Scott

    Inventor： David F. Horrobin ,  Catherine A. Scott

    IPC: A61K31/20 ,  A61K20060101 ,  A61K9/08 ,  A61K31/201 ,  A61K31/202 ,  A61K31/203 ,  A61K33/00

    CPC classification number: A61K31/20

    Abstract: Method of safe intravenous administration of fatty acid(s), and in particular the n-6 and n-3 series essential fatty acids and conjugated fatty acids, whereby the fatty acid(s) or a proportion thereof are administered in the form of lithium salts, and whereby the plasma lithium levels are regularly monitored to avoid haemolysis, preferably keeping the lithium level no higher than 0.7 millimolar in the long term and preferably also no higher than 0.4-0.5 millimolar in the first 24-48 hours or, where only a proportion of the fatty acids are administered as lithium salts, a corresponding proportion of said levels.

    Abstract translation: 脂肪酸的安全静脉内给药方法，特别是n-6和n-3系列必需脂肪酸和共轭脂肪酸，其中脂肪酸或其一部分以锂的形式施用 盐，并且由此定期监测血浆锂水平以避免溶血，优选在长期内保持锂水平不高于0.7毫摩尔，优选在第一24-48小时内不超过0.4-0.5毫摩尔，或者仅在 一部分脂肪酸以锂盐的形式施用，相应比例的水平。

    Method of increasing the total fat content of milk
    38.
    发明授权
    Method of increasing the total fat content of milk 失效
    增加牛奶总脂肪含量的方法

    公开(公告)号：US5264217A

    公开(公告)日：1993-11-23

    申请号：US959472

    申请日：1992-10-09

    Applicant: David F. Horrobin

    Inventor： David F. Horrobin

    IPC: A61K31/20

    CPC classification number: A61K31/20 ,  Y10S514/922

    Abstract: Methods for increasing the total fat and therefore energy content of mammalian and particularly human milk, the essential fatty acid content of that milk and the flow of that milk during lactation, or for preventing or reducing the normal decrease in milk fat content that occurs during prolonged lactation, by administering gamma linolenic acid, dihomo-gamma-linolenic acid or their mixture, alone or a physiologically acceptable diluent or carrier, in a form administrable to the lactating female.

    Abstract translation: 增加哺乳动物和特别是人乳的总脂肪，因此能量含量的方法，该乳的必需脂肪酸含量和哺乳期间该奶的流动，或用于预防或减少在长时间内发生的乳脂含量的正常降低 通过以可施用于哺乳期雌性的形式单独或单独或生理上可接受的稀释剂或载体施用γ-亚麻酸，二亚非 - γ-亚麻酸或其混合物。

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