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公开(公告)号：US08986260B2
公开(公告)日：2015-03-24
申请号：US14007086
申请日：2012-03-22
CPC分类号： A61M5/31533 , A61M5/24 , A61M5/31525 , A61M5/31535 , A61M5/31565 , A61M5/31566
摘要： A dose setting mechanism comprising a dose setting member and a drive member for driving a piston rod in a distal direction during dose dispensing. The drive member comprises a proximal drive member and a distal drive member. A first clutch releasably coupling the proximal drive member and the distal drive member. A spring means biases the proximal drive member and the distal drive member in the coupled state during dose setting and dose dispensing. Engaging means are provided associated to the proximal drive member and to the dose setting member, wherein the engaging means are designed and arranged such that the proximal drive member entrains the dose setting member in the distal direction during dose setting but allows a relative axial movement of the proximal drive member with respect to the dose setting member in the proximal direction.
摘要翻译： 一种剂量设定机构，包括剂量设定构件和用于在剂量分配期间沿远端方向驱动活塞杆的驱动构件。 驱动构件包括近侧驱动构件和远侧驱动构件。 可释放地联接近侧驱动构件和远侧驱动构件的第一离合器。 弹簧装置在剂量设定和剂量分配期间以耦合状态偏压近侧驱动构件和远侧驱动构件。 提供与近端驱动构件和剂量设定构件相关联的接合装置，其中接合装置被设计和布置成使得近侧驱动构件在剂量设定期间沿远端方向夹带剂量设定构件，但允许相对轴向运动 所述近侧驱动构件相对于所述剂量设定构件在所述近端方向上。
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公开(公告)号：US08603044B2
公开(公告)日：2013-12-10
申请号：US13909649
申请日：2013-06-04
IPC分类号： A61M5/00
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
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公开(公告)号：US20130274680A1
公开(公告)日：2013-10-17
申请号：US13909649
申请日：2013-06-04
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
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34.发明申请公开(公告)号：US20130211343A1
公开(公告)日：2013-08-15
申请号：US13825841
申请日：2011-10-05
CPC分类号： A61M5/31511 , A61M5/31515 , A61M5/31555 , A61M5/3156 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , F16H25/2015 , Y10T74/18688
摘要： A lead screw, a lead screw nut and a drive member are aligned with an axis defining an axial direction and an opposite axial direction. A coupling between the lead screw and the lead screw nut allows a helical movement of the lead screw with respect to the lead screw nut at least in the axial direction. The lead screw is coupled with the drive member, the coupling generating a helical movement of the lead screw with respect to the drive member when the drive member is moved in the axial direction with respect to the lead screw. A dispense stop feature of the lead screw nut and a dispense stop feature of the drive member prevent the generation of the helical movement of the lead screw when a specified end position of the drive member is approached.
摘要翻译： 导螺杆，丝杠螺母和驱动构件与限定轴向方向和相反轴向的轴对准。 导螺杆和导螺杆螺母之间的联接允许丝杆相对于丝杠螺母至少沿轴向方向螺旋运动。 导螺杆与驱动构件联接，当驱动构件相对于导螺杆沿轴向移动时，联接器相对于驱动构件产生螺杆运动。 导向螺母的分配停止特征和驱动部件的分配停止特征防止当接近驱动部件的指定的结束位置时产生螺杆的螺旋运动。
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公开(公告)号：US20130184650A1
公开(公告)日：2013-07-18
申请号：US13825813
申请日：2011-10-05
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/31555 , A61M5/3156 , A61M5/31585 , A61M5/31593 , A61M2005/2407
摘要： A lead screw, a lead screw nut and a drive member are aligned with an axis. A coupling between the lead screw and the lead screw nut allows a helical movement of the lead screw. The drive member is rotationally locked with the lead screw nut. The lead screw is coupled with the drive member to generate a helical movement of the lead screw when the drive member is moved in one axial direction. The coupling is overridden when the drive member is moved in the opposite axial direction. Spline features are arranged on the lead screw in a row parallel to the axis with alternatingly small and large gaps between succeeding spline features. A stop feature of the drive member has a dimension in the direction of the axis which is larger than the small gaps and at most as large as the large gaps.
摘要翻译： 导螺杆，丝杠螺母和驱动部件与轴对齐。 导螺杆和导螺杆螺母之间的联轴器允许螺杆的螺旋运动。 驱动构件与导螺杆螺母旋转锁定。 当驱动构件沿一个轴向移动时，导螺杆与驱动构件联接以产生螺杆的螺旋运动。 当驱动构件沿相反的轴向移动时，联接被覆盖。 花键特征被布置在导螺杆上，平行于轴线，后续花键特征之间具有交替的较小和较大的间隙。 驱动构件的止动特征在轴线方向上的尺寸大于小间隙，并且至多与大间隙一样大。
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公开(公告)号：US20110276009A1
公开(公告)日：2011-11-10
申请号：US12941702
申请日：2010-11-08
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
摘要翻译： 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用，例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体，剂量拨号套筒和驱动套筒。 离合器构造成当剂量拨盘套筒和驱动套筒通过离合器联接时允许驱动套筒和剂量拨盘套筒相对于壳体旋转。 相反，当剂量拨号套筒和驱动套筒处于脱耦合状态时，允许剂量拨盘套筒相对于壳体的旋转，并且防止驱动套筒相对于壳体的旋转。 在脱耦合状态下，驱动套筒的轴向运动在纵向方向上传递力，用于致动药物输送装置。
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公开(公告)号：US20090198193A1
公开(公告)日：2009-08-06
申请号：US12320189
申请日：2009-01-21
IPC分类号： A61M5/31
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
摘要翻译： 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用，例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体，剂量拨号套筒和驱动套筒。 离合器构造成当剂量拨盘套筒和驱动套筒通过离合器联接时允许驱动套筒和剂量拨盘套筒相对于壳体旋转。 相反，当剂量拨号套筒和驱动套筒处于脱耦合状态时，允许剂量拨盘套筒相对于壳体的旋转，并且防止驱动套筒相对于壳体的旋转。 在脱耦合状态下，驱动套筒的轴向运动在纵向方向上传递力，用于致动药物输送装置。
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公开(公告)号：US07185585B2
公开(公告)日：2007-03-06
申请号：US11220190
申请日：2005-09-01
IPC分类号： B30B9/32
CPC分类号： B30B9/3071 , B29B17/0052 , B29B2017/0057 , B29B2017/0068 , B30B9/321 , Y02W30/62 , Y10S100/902
摘要： An apparatus for crushing containers includes a die defining an opening, a punch, and a system for displacing the die and punch relative to each other. The punch may be fixed and the die may be moved from a first position spaced apart from the punch such that a container to be crushed can be placed between the punch and die and a second position in which the punch extends into the die opening to define an annular gap between the punch and die opening. The arrangement is such that a container crushed between the die and punch as a result of displacement of the die to the second position is at least in part forced into and deformed within the annular gap.
摘要翻译： 用于破碎容器的装置包括限定开口的模具，冲头和用于相对于彼此移动模具和冲头的系统。 冲头可以是固定的，并且模具可以从与冲头隔开的第一位置移动，使得要被压碎的容器可以被放置在冲头和模具之间，并且第二位置中冲头延伸到模具开口中以限定 冲头和模具开口之间的环形间隙。 这种布置使得由于模具移动到第二位置的结果，在模具和冲头之间被压碎的容器至少部分地被迫进入并在环形间隙内变形。
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公开(公告)号：USD514227S1
公开(公告)日：2006-01-31
申请号：US29187442
申请日：2003-07-31
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公开(公告)号：US09457150B2
公开(公告)日：2016-10-04
申请号：US12788692
申请日：2010-05-27
CPC分类号： A61M5/24 , A61M5/31551 , A61M2005/2407 , A61M2005/2477 , A61M2005/2488 , A61M2005/2492 , F16F1/025 , Y10T29/49826
摘要： A method and system for biasing a cartridge in a drug delivery device. An element for biasing a cartridge in a cartridge housing of a drug delivery device is provided. This non-plastic element does not comprise a coil spring. A self retained element for providing a spring bias to a cartridge in a cartridge holder of a drug delivery device comprises a first member having a shape that allows passage of a spindle of the drug delivery device. A portion of the first member is self retained by an internal surface of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge holder. This cartridge could be a removable cartridge.
摘要翻译： 一种用于在药物输送装置中偏置药筒的方法和系统。 提供了用于将药筒偏置在药物输送装置的药筒外壳中的元件。 该非塑料元件不包括螺旋弹簧。 用于向药物输送装置的药筒保持器中的药筒提供弹簧偏压的自身保持元件包括具有允许药物递送装置的心轴通过的形状的第一构件。 第一构件的一部分由药物递送装置的内表面自身保留。 自保持元件将盒抵靠在盒保持器的内表面上。 该墨盒可以是可拆卸墨盒。
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