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公开(公告)号:US20220008233A1
公开(公告)日:2022-01-13
申请号:US17485239
申请日:2021-09-24
Applicant: Edwards Lifesciences Corporation
Inventor: Nima V. Nia , Hengchu Cao , Sakyasingh Tripathy , Douglas Thomas Dominick , Bingquan Su , Behnood Miri , Zahra Moyedi
Abstract: Described herein are artificial valves that have a frame and leaflets that grow or expand with a patient. Upon placing the valve inside the patient, the valve expands as the annulus of the patient expands. The frame of the valve is configured to expand which in turn causes the leaflets to expand (e.g., to grow). The valve includes a thin undulating wire embedded inside the leaflets. As the annulus of the patient grows, the frame expands, and as the frame expands, the leaflets grow. The growth or expansion of the leaflets is configured so that the valve continues to operate properly (e.g., the leaflets continue to coapt) with expansion of the annulus. The change in size of the valve can be configured to accommodate changes in size of the annulus from an infant or child to an adult.
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公开(公告)号:US11096784B2
公开(公告)日:2021-08-24
申请号:US15909803
申请日:2018-03-01
Applicant: Edwards Lifesciences Corporation
Inventor: Eric Robert Dixon , Hengchu Cao , Douglas Thomas Dominick , Lauren R. Freschauf
IPC: A61F2/24 , A61B17/128 , A61B17/122 , A61B17/00 , A61B17/064 , A61F2/00
Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.
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公开(公告)号:US11058539B2
公开(公告)日:2021-07-13
申请号:US15910951
申请日:2018-03-02
Applicant: Edwards Lifesciences Corporation
Inventor: Eric Robert Dixon , Jensen Chen , Guillermo W. Moratorio , Hengchu Cao , Douglas Thomas Dominick , Sergio Delgado
IPC: A61F2/24 , A61B17/128 , A61B17/122 , A61B17/00 , A61B17/064 , A61F2/00
Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.
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公开(公告)号:US20200330226A1
公开(公告)日:2020-10-22
申请号:US16921901
申请日:2020-07-06
Applicant: Edwards Lifesciences Corporation
Inventor: Hengchu Cao , Brian S. Conklin , Paul A. Schmidt , Grace Myong Kim , James A. Davidson , Hoa Trinh Tran , Kristy Luong Tam
IPC: A61F2/24
Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.
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公开(公告)号:US20200078011A1
公开(公告)日:2020-03-12
申请号:US16680336
申请日:2019-11-11
Applicant: Edwards Lifesciences Corporation
Inventor: Manouchehr A. Miraki , Hengchu Cao , Ralph Schneider
IPC: A61B17/04
Abstract: Some disclosed suture securement devices comprise a flat, thin, generally planar body that has one or more suture engagement slots extending into the body from a perimeter inlet for receiving sutures laterally into the device. The slots can be resiliently widened to receive a suture and then released to clamp onto the suture. Some embodiments include two or more such suture engagement slots that independently receive and secure different sutures. Some embodiments include one or more locking tabs that have a closed position that retains the slots against widening and blocks the inlet to the slot. In some embodiment two or more slots are position next to each other on the same side of the device, while in other embodiments slots are positioned on opposite sides of the device. Other types of suture securement devices are also disclosed.
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公开(公告)号:US10463480B2
公开(公告)日:2019-11-05
申请号:US15403423
申请日:2017-01-11
Applicant: Edwards Lifesciences Corporation
Inventor: Hengchu Cao , Wei Sun
Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.
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公开(公告)号:US20180296327A1
公开(公告)日:2018-10-18
申请号:US15884193
申请日:2018-01-30
Applicant: Edwards Lifesciences Corporation
Inventor: Eric Robert Dixon , Jensen Chen , Guillermo W. Moratorio , Hengchu Cao , Douglas Thomas Dominick , Sergio Delgado , Lauren R. Freschauf
IPC: A61F2/24
Abstract: An implantable prosthetic device such as might be used to treat poor function of a diseased heart valve in a medical patient includes a body portion and an anchor portion including a plurality of paddles. Clasps attached to the paddles include fixed arms and moveable arms operable to secure the device to the patient's native valve leaflets.
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公开(公告)号:US09498202B2
公开(公告)日:2016-11-22
申请号:US13938071
申请日:2013-07-09
Applicant: Edwards Lifesciences Corporation
Inventor: Mohammad Jafari , Ming H. Wu , Hengchu Cao , Ralph Schneider , Manouchehr A. Miraki
IPC: A61B17/04 , A61B17/064 , A61F2/08 , B65D33/16 , A61F2/24
CPC classification number: A61B17/0401 , A61B17/0487 , A61B17/0642 , A61B2017/0404 , A61B2017/0406 , A61B2017/0419 , A61B2017/042 , A61B2017/0437 , A61B2017/0438 , A61B2017/0446 , A61B2017/0448 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/049 , A61F2/0811 , A61F2/2448 , B65D33/1625 , Y10T24/155 , Y10T24/44923
Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.
Abstract translation: 这里公开了缝合线固定装置的示例性实施例,其代替在缝合线中结扎的需要。 一些实施例包括环形外体和从外体向内延伸的一个或多个缝合线接合片。 该装置可以包括超弹性和/或形状记忆材料,并且具有大致平面的初始构型。 缝合线接合部分可以在平面外成形为活动构型,外部主体被压缩,并且翼片彼此互锁。 该设备可以在变形的配置中进行热定形。 互锁的舌片在通过它们之间的缝合线上施加夹紧力,其限制缝合线在一个纵向方向上滑动通过开口。
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公开(公告)号:US20240041483A1
公开(公告)日:2024-02-08
申请号:US18367021
申请日:2023-09-12
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Sakyasingh Tripathy , Hengchu Cao , Nima V. Nia , Douglas Thomas Dominick , Bingquan Su , Amanda Tjipta Sugijoto
CPC classification number: A61B17/22031 , A61B17/00234 , A61B17/22 , A61B2017/00349 , A61B2017/22098 , A61B2017/308
Abstract: A method and device for advancing a guidewire past a calcified leaflet of a heart valve are described. A dual guidewire device includes a primary guidewire, a secondary guidewire, and a sheath. The primary guidewire is configured to advance past a heart valve while the secondary guidewire is configured to pull open the calcified leaflet of the heart valve while the primary guidewire advances past the heart valve. The catheter can contain both the primary guidewire and the secondary guidewire.
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公开(公告)号:US11759200B2
公开(公告)日:2023-09-19
申请号:US16680336
申请日:2019-11-11
Applicant: Edwards Lifesciences Corporation
Inventor: Manouchehr A. Miraki , Hengchu Cao , Ralph Schneider
IPC: A61B17/04
CPC classification number: A61B17/0487 , A61B2017/0404 , A61B2017/0438 , A61B2017/0454
Abstract: Some disclosed suture securement devices comprise a flat, thin, generally planar body that has one or more suture engagement slots extending into the body from a perimeter inlet for receiving sutures laterally into the device. The slots can be resiliently widened to receive a suture and then released to clamp onto the suture. Some embodiments include two or more such suture engagement slots that independently receive and secure different sutures. Some embodiments include one or more locking tabs that have a closed position that retains the slots against widening and blocks the inlet to the slot. In some embodiment two or more slots are position next to each other on the same side of the device, while in other embodiments slots are positioned on opposite sides of the device. Other types of suture securement devices are also disclosed.
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