公开(公告)号：US20180228605A1

公开(公告)日：2018-08-16

申请号：US15918572

申请日：2018-03-12

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2427 ,  A61F2/0095 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

公开(公告)号：US20170281340A1

公开(公告)日：2017-10-05

申请号：US15617906

申请日：2017-06-08

Applicant: Edwards Lifesciences Corporation

Inventor： Jessica Guttenberg ,  Da-Yu Chang ,  Derrick Johnson ,  Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2250/0085 ,  A61F2250/0089 ,  A61F2250/0098

Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.

公开(公告)号：US20170239044A1

公开(公告)日：2017-08-24

申请号：US15591915

申请日：2017-05-10

Applicant: Edwards Lifesciences Corporation

Inventor： Derrick Johnson ,  Van Huynh ,  Qinggang Zeng

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2210/00 ,  A61F2250/006 ,  A61F2310/00389

Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.

公开(公告)号：US20170000604A1

公开(公告)日：2017-01-05

申请号：US15199748

申请日：2016-06-30

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2210/0057 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0048 ,  A61F2250/006 ,  A61F2250/0097

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.

Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 假体心脏瓣膜可以被构造成当最初植入时具有大致刚性和/或抗膨胀的构造，以替代天然瓣膜（或其他假体心脏瓣膜），但是当受到向外的力（例如， 由膨胀气球或其他机械膨胀机提供。 流入支架框架是可扩张的，用于将阀固定在适当位置，并且可以具有在有限程度上可折叠的流出端，用于输送和可扩展的植入后可促进阀门（ViV）程序。 混合心脏瓣膜消除了早期的结构带，这既减少了制造时间又促进了ViV程序。

公开(公告)号：US09314334B2

公开(公告)日：2016-04-19

申请号：US14089723

申请日：2013-11-25

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Travis Oba ,  Tammy Huntley ,  Qinggang Zeng ,  August R. Yambao ,  Rafael Pintor

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2/243 ,  A61F2220/0008 ,  A61F2230/0054 ,  A61F2250/0003

Abstract: A system for expanding a device in a conduit or orifice of a human body includes an expansion device that is movable from a first configuration to a second configuration. External surfaces of the expansion device can collectively have a non-cylindrical cross-section relative to a main axis of the expansion device, such that the external surfaces of the expansion device generally conform to the anatomical shape of the conduit or orifice when the expansion device is in the second configuration.

Abstract translation: 一种用于在人体的管道或孔中扩张装置的系统包括可从第一构型移动到第二构造的膨胀装置。 膨胀装置的外表面可以相对于膨胀装置的主轴线共同具有非圆柱形横截面，使得当膨胀装置的膨胀装置的外表面大致符合导管或孔口的解剖形状时 处于第二个配置。

公开(公告)号：US12053377B2

公开(公告)日：2024-08-06

申请号：US18046475

申请日：2022-10-13

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Michael J. Scott ,  Thomas Chien ,  Harvey H. Chen ,  August R. Yambao ,  Lawrence J. Farhat ,  Andrew Phung ,  William C. Brunnett ,  Carey L. Cristea ,  Sara M. Walls ,  Kevin W. Zheng ,  Faisal Kalam ,  Qinggang Zeng

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0067 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0048 ,  A61F2250/006

Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

公开(公告)号：US12011350B2

公开(公告)日：2024-06-18

申请号：US18056691

申请日：2022-11-17

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L Cristea ,  Faisal Kalam

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US20230072121A1

公开(公告)日：2023-03-09

申请号：US18046475

申请日：2022-10-13

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Michael J. Scott ,  Thomas Chien ,  Harvey H. Chen ,  August R. Yambao ,  Lawrence J. Farhat ,  Andrew Phung ,  William C. Brunnett ,  Carey L. Cristea ,  Sara M. Walls ,  Kevin W. Zheng ,  Faisal Kalam ,  Qinggang Zeng

IPC: A61F2/24

Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

公开(公告)号：US11504232B2

公开(公告)日：2022-11-22

申请号：US17067618

申请日：2020-10-09

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US11173032B2

公开(公告)日：2021-11-16

申请号：US16112388

申请日：2018-08-24

Applicant: Edwards Lifesciences Corporation

Inventor： Qinggang Zeng

IPC: A61F2/24

Abstract: The invention is a prosthetic device for improving function of a mitral valve. The device includes a sealing member configured for positioning between mitral valve leaflets. The device also includes an expandable anchor frame configured to be positioned within one or more heart chambers, for maintaining the sealing member at a desired position between valve leaflets. The sealing member reduces mitral regurgitation be filling the gap that can occur between opposing leaflets of a damaged mitral valve, thus restoring proper mitral valve closure.