公开(公告)号：US20100033324A1

公开(公告)日：2010-02-11

申请号：US12442961

申请日：2007-09-27

申请人： Jeff Shimizu ,  Hans Zou ,  Johan Frederik Dijksman ,  Anke Pierik ,  Judith Margaret Rensen

发明人： Jeff Shimizu ,  Hans Zou ,  Johan Frederik Dijksman ,  Anke Pierik ,  Judith Margaret Rensen

IPC分类号： G08B21/00

CPC分类号： A61M5/14276 ,  A61B5/073 ,  A61B2562/0214 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2210/1053

摘要： A sensor comprising a plurality of electrodes having a miniature size and a lower power consumption and a coating exterior to the electrodes, wherein the coating interacts with a target condition thereby producing a change in an electrical property of the electrodes, wherein the change is transduced into an electrical signal by the electrodes. Further a system for medication delivery comprising such sensor and a pill.

摘要翻译： 一种传感器，包括具有微小尺寸和较低功率消耗的多个电极以及电极外部的涂层，其中所述涂层与目标条件相互作用，从而产生电极的电性能的变化，其中所述变化被转换成 电极的电信号。 另外，用于药物输送的系统包括这种传感器和丸剂。

公开(公告)号：US08374685B2

公开(公告)日：2013-02-12

申请号：US12529552

申请日：2008-03-07

申请人： Antonius Theodorus Martinus Van Gogh ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Hans Zou ,  Maarten Marinus Johannes Wilhelmus Van Herpen

发明人： Antonius Theodorus Martinus Van Gogh ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Hans Zou ,  Maarten Marinus Johannes Wilhelmus Van Herpen

IPC分类号： A61B6/08 ,  G01J4/00 ,  G01J3/447 ,  G01N21/47

CPC分类号： A61B5/0075 ,  A61B5/0084 ,  G01N21/4795 ,  G01N2021/4792

摘要： A system (40) for diagnosis and staging of early stages of cancer in the tissue of a patient is provided. The system—is configured to combine information from a Polarized Light Scattering Spectroscopy measurement (70) having a first probe depth, and a Differential Path Length Spectroscopy measurement (60) having a second probe depth, wherein the second probe depth is set larger than' the first probe depth. By comparing the results of the Polarized Light Scattering Spectroscopy and Differential Path Length Spectroscopy measurements early stages of cancer, such as dysplasia may be detected. Also hyperplasia, carcinoma in situ, and carcinoma may be detected. A computer-readable medium, method and use are also provided.

摘要翻译： 提供了一种用于诊断和分期患者组织中癌症早期阶段的系统（40）。 该系统被配置为组合来自具有第一探测深度的偏振光散射光谱测量（70）和具有第二探测深度的差分路径长度光谱测量（60）的信息，其中第二探测深度被设置为大于“ 第一探测深度。 通过比较极化光散射光谱和差分路径长度光谱测量的结果，可以检测癌症的早期阶段，例如发育异常。 也可能检测到增生，原位癌和癌。 还提供了计算机可读介质，方法和用途。

公开(公告)号：US20140024428A1

公开(公告)日：2014-01-23

申请号：US13946393

申请日：2013-07-19

申请人： Jordan Solomon ,  Hans Zou ,  Herbert Tsui

发明人： Jordan Solomon ,  Hans Zou ,  Herbert Tsui

IPC分类号： G07F17/32

CPC分类号： G07F17/329 ,  G07F17/326

摘要： A system and method for processing game sessions of a game having a common playing card is provided where the game sessions are initiated from communication devices in a network. For the system, there is a server and a database. The server is for managing execution of a plurality of game sessions in a game pool for the game accessed by the plurality of communication devices in the network. The server is also for a game session of the game sessions evaluating credentials and restrictions of an account associated with a user of a communication device that initiated the game session; providing a set of numbers to be played for the game session; tracking winning conditions for the game session; tracking a log time for the game session for the communication device; and generating a report of the log time when the game is completed at the communication device. The database is for storing and updating a record of the game session and the log time with records of other game sessions associated with the game sessions.

摘要翻译： 提供了一种用于处理具有公共扑克牌的游戏的游戏会话的系统和方法，其中游戏会话从网络中的通信设备发起。 对于系统，有一个服务器和一个数据库。 服务器用于管理由网络中的多个通信设备访问的游戏的游戏池中的多个游戏会话的执行。 服务器还用于游戏会话的游戏会话，其评估与启动游戏会话的通信设备的用户相关联的帐户的凭证和限制; 提供一组要玩游戏的数字; 跟踪游戏会话的获胜条件; 跟踪通信设备的游戏会话的日志时间; 以及在通信装置完成游戏时生成记录时间的报告。 该数据库用于存储和更新游戏会话的记录和日志时间以及与游戏会话相关联的其他游戏会话的记录。

公开(公告)号：US08175690B2

公开(公告)日：2012-05-08

申请号：US12527727

申请日：2008-02-18

申请人： Bernardus H. W. Hendriks ,  Antonius T. M. Van Gogh ,  Hans Zou

发明人： Bernardus H. W. Hendriks ,  Antonius T. M. Van Gogh ,  Hans Zou

IPC分类号： A61B6/00 ,  A61B6/08 ,  G01J4/00 ,  G01J3/447 ,  G01N21/47

CPC分类号： A61B5/0084 ,  A61B5/0075 ,  A61B5/444 ,  A61B2562/0242 ,  G01N21/4795 ,  G01N2021/4792

摘要： An optical device for assessing optical depth in a sample illuminated by polarized radiation from a source include two radiation guides having their end portions arranged for capturing reflected radiation from the sample. A detector measures two polarizations of the reflected radiation, and two intensities of the reflected radiation in the two radiation guides, respectively. A processor is configured to calculate two pectral functions, which are indicative of single scattering events in the sample. The processor is further configured to calculate a measure of the correlation between the two spectral functions so as to assess whether the single scattering events originate from substantially the same optical depth within the sample. Thus, the causal relation between the two spectral functions can be used for assessing whether the single scattering events giving rise to the two spectral functions come from substantially the same optical depth within the sample.

摘要翻译： 用于评估由来自源的偏振辐射照射的样品中的光学深度的光学装置包括两个辐射导向件，其具有被布置成用于捕获来自样品的反射辐射的端部。 检测器分别测量两个辐射导向器中反射辐射的两个偏振和两个反射辐射强度。 处理器被配置为计算两个波纹函数，其表示样本中的单个散射事件。 处理器还被配置为计算两个光谱函数之间的相关性的度量，以便评估单个散射事件是否源自样本内的基本相同的光学深度。 因此，两个光谱函数之间的因果关系可用于评估引起两个光谱函数的单个散射事件是否来自样本内的基本相同的光学深度。

公开(公告)号：US20080266224A1

公开(公告)日：2008-10-30

申请号：US11814084

申请日：2006-01-19

申请人： Marcellinus Petrus Carolus Michael Krijn ,  Oscar Hendrikus Willemsen ,  Hans Zou

发明人： Marcellinus Petrus Carolus Michael Krijn ,  Oscar Hendrikus Willemsen ,  Hans Zou

IPC分类号： G09G3/36

CPC分类号： G09G3/3607 ,  G09G3/3413 ,  G09G3/3629 ,  G09G2310/0235

摘要： A display arrangement comprises a plurality of pixel elements (FLCD) that have controllable light-transfer characteristics. A display driver controls the plurality of pixel elements in accordance with a color component (R) during a control interval (TO) that is assigned to the color component. The display driver causes a color-light source (RL1, RL2) to apply a color light, which corresponds to the color component, to the plurality of pixel elements during a main interval (RMO). The main interval is comprised in the control interval that is assigned to color component. The light-source controller also causes the color-light source to apply the color light during a spillover interval (RS1, RS2). The spillover interval is comprised in another control interval (T1) that is assigned to another color component (G).

摘要翻译： 显示装置包括具有可控光传输特性的多个像素元件（FLCD）。 显示驱动器在分配给颜色分量的控制间隔（TO）期间根据颜色分量（R）来控制多个像素元件。 显示驱动器使得颜色光源（RL 1，RL 2）在主间隔（RMO）期间将对应于颜色分量的颜色光施加到多个像素元件。 主间隔包含在分配给颜色分量的控制间隔中。 光源控制器还使彩色光源在溢出间隔（RS 1，RS 2）期间施加彩色光。 溢出间隔包含在分配给另一颜色分量（G）的另一个控制间隔（T 1）中。

公开(公告)号：US07631991B2

公开(公告)日：2009-12-15

申请号：US11575702

申请日：2005-09-22

申请人： Duncan J. Anderson ,  Hans Zou

发明人： Duncan J. Anderson ,  Hans Zou

IPC分类号： F21V5/00

CPC分类号： H01L33/60 ,  H01L33/58

摘要： Light that is emitted from an LED chip at a first angle of incidence or less relative to the LED chip is permitted to leave the LED package. Light emitted from the LED chip at an angle of incidence greater than that is kept from leaving the LED package and is recycled back within the LED package. The recycled light is reemitted from the LED package after its angle of incidence relative to the LED chip has been changed, for example by passing it through a diffuser.

摘要翻译： 允许以相对于LED芯片的第一入射角或更小的LED芯片发射的光离开LED封装。 以较大的入射角从LED芯片发射的光不会离开LED封装并被再循环回到LED封装内。 在LED封装中，相对于LED芯片的入射角已经改变，例如通过将其通过扩散器，再循环的光被重新发射。

公开(公告)号：US20090185384A1

公开(公告)日：2009-07-23

申请号：US11575702

申请日：2005-09-22

申请人： Duncan J. Anderson ,  Hans Zou

发明人： Duncan J. Anderson ,  Hans Zou

IPC分类号： F21V5/00

CPC分类号： H01L33/60 ,  H01L33/58

摘要： Light that is emitted from an LED chip at a first angle of incidence or less relative to the LED chip is permitted to leave the LED package. Light emitted from the LED chip at an angle of incidence greater than that is kept from leaving the LED package and is recycled back within the LED package. The recycled light is reemitted from the LED package after its angle of incidence relative to the LED chip has been changed, for example by passing it through a diffuser.

摘要翻译： 允许以相对于LED芯片的第一入射角或更小的LED芯片发射的光离开LED封装。 以较大的入射角从LED芯片发射的光不会离开LED封装并被再循环回到LED封装内。 在LED封装中，相对于LED芯片的入射角已经改变，例如通过将其通过扩散器，再循环的光被重新发射。

公开(公告)号：US20090149761A1

公开(公告)日：2009-06-11

申请号：US12302346

申请日：2007-04-11

申请人： Hans Zou ,  Ladislav Jankovic

发明人： Hans Zou ,  Ladislav Jankovic

IPC分类号： A61B6/00

CPC分类号： A61B5/0073 ,  A61B5/0095 ,  G01N21/1702

摘要： This invention discloses a method to position, identify and characterize a photoacoustic source in a complex environment. This method isolates individual acoustic responses from interferences by spectral analysis and filtering and locates primary acoustic sources by applying beam-forming to decomposed acoustic responses. The photon-absorbing structure of a tissue can be constructed with primary source parameters.

摘要翻译： 本发明公开了一种在复杂环境中定位，识别和表征光声源的方法。 该方法通过光谱分析和滤波将各个声响应与干扰隔离，并通过对分解声响应进行波束形成来定位主声源。 组织的光子吸收结构可以用主要的参数来构造。

公开(公告)号：US20100113941A1

公开(公告)日：2010-05-06

申请号：US12527727

申请日：2008-02-18

申请人： Bernardus H.W. Hendriks ,  Antonius T.M. Van Gogh ,  Hans Zou

发明人： Bernardus H.W. Hendriks ,  Antonius T.M. Van Gogh ,  Hans Zou

IPC分类号： A61B6/00 ,  G01J3/447 ,  G01J4/00 ,  G01N21/47

CPC分类号： A61B5/0084 ,  A61B5/0075 ,  A61B5/444 ,  A61B2562/0242 ,  G01N21/4795 ,  G01N2021/4792

摘要： The present invention relates to an optical device for assessing optical depth (D) in a sample (100) illuminated by polarized radiation (20) from a source (10). A first and a second radiation guide have their end portions (3Oa′, 30b′) arranged for capturing reflected radiation (25a, 25b) from the sample. A detector (40) measures a first polarization (P1) and a second polarization (P—2) of the reflected radiation (25), and a first and a second intensity (II, 12) of the reflected radiation (25a, 25b) in the first (30a) and the second (30b) radiation guide, respectively. Processing means (60) then calculates a first (f) and a second (g) spectral function, both spectral functions (f, g) being indicative of single scattering events in the sample. The processing means (60) is further arranged to calculate a measure of the correlation (C) between the first (f) and a second (g) spectral function so as to assess whether the single scattering events originate from substantially the same optical depth (D) within the sample. Thus, the causal relation between the first and second spectral functions can be used for assessing whether the single scattering events giving rise to the two spectral functions come from substantially the same optical depth (D) within the sample. The invention is particular advantageous for optically probing an epithelial layer of a patient.

摘要翻译： 本发明涉及一种用于评估从源极（10）被偏振辐射（20）照射的样品（100）中的光学深度（D）的光学装置。 第一和第二辐射引导件具有其端部（30a'，30b'），用于从样品捕获反射辐射（25a，25b）。 检测器（40）测量反射辐射（25）的第一偏振（P1）和第二偏振（P-2），以及反射辐射（25a，25b）的第一和第二强度（II，12） 分别在第一（30a）和第二（30b）辐射导向件中。 处理装置（60）然后计算第一（f）和第二（g）光谱函数，两个光谱函数（f，g）指示样本中的单个散射事件。 处理装置（60）还被布置成计算第一（f）和第二（g）光谱函数之间的相关性（C）的度量，以便评估单个散射事件是否源于基本上相同的光学深度（ D）样品内。 因此，第一和第二光谱函数之间的因果关系可用于评估引起两个光谱函数的单个散射事件是否来自样本内的基本相同的光学深度（D）。 本发明特别有利于光学检测患者的上皮层。

公开(公告)号：US20100056927A1

公开(公告)日：2010-03-04

申请号：US12529552

申请日：2008-03-07

申请人： Antonius T.M. Van Gogh ,  Bernardus H.W. Hendriks ,  Hans Zou ,  Maarten M.J.W. Van Herpen

发明人： Antonius T.M. Van Gogh ,  Bernardus H.W. Hendriks ,  Hans Zou ,  Maarten M.J.W. Van Herpen

IPC分类号： A61B6/00 ,  G01J3/00

CPC分类号： A61B5/0075 ,  A61B5/0084 ,  G01N21/4795 ,  G01N2021/4792

摘要： A system (40) for diagnosis and staging of early stages of cancer in the tissue of a patient is provided. The system is configured to combine information from a Polarized Light Scattering Spectroscopy measurement (70) having a first probe depth, and a Differential Path Length Spectroscopy measurement (60) having a second probe depth, wherein the second probe depth is set larger than' the first probe depth. By comparing the results of the Polarized Light Scattering Spectroscopy and Differential Path Length Spectroscopy measurements early stages of cancer, such as dysplasia may be detected. Also hyperplasia, carcinoma in situ, and carcinoma may be detected. A computer-readable medium, method and use are also provided.

摘要翻译： 提供了一种用于诊断和分期患者组织中癌症早期阶段的系统（40）。 该系统被配置为组合来自具有第一探测深度的偏振光散射光谱测量（70）和具有第二探测深度的差分路径长度光谱测量（60）的信息，其中第二探测深度被设置为大于 第一探测深度。 通过比较极化光散射光谱和差分路径长度光谱测量的结果，可以检测癌症的早期阶段，例如发育异常。 也可能检测到增生，原位癌和癌。 还提供了计算机可读介质，方法和用途。