公开(公告)号：US20050228454A1

公开(公告)日：2005-10-13

申请号：US11142165

申请日：2005-06-01

申请人： Andrew Kramer ,  Jeffrey Stahmann ,  Veerichetty Kadhiresan

发明人： Andrew Kramer ,  Jeffrey Stahmann ,  Veerichetty Kadhiresan

IPC分类号： A61N1/362 ,  A61N1/365 ,  A61N1/368

CPC分类号： A61N1/3627 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/3682 ,  A61N1/3684

摘要： A method of optimizing cardiac resynchronization therapy delay over a patient's full range of activity for use in operating an implantable cardiac pacing device and such a device are disclosed. The method includes measuring selected conduction time between selected sites in the heart for a plurality of beats and logging the values on a periodic repeating programmable basis to produce cumulative data and constructing a current template of conduction time in relation to one or more other sensed parameters of interest over a desired range of patient activity levels. The current template is used to derive suggested optimum pacing timing.

公开(公告)号：US20050004606A1

公开(公告)日：2005-01-06

申请号：US10839268

申请日：2004-05-05

申请人： Jeffrey Stahmann ,  Andrew Kramer ,  Hugh Calkins

发明人： Jeffrey Stahmann ,  Andrew Kramer ,  Hugh Calkins

IPC分类号： A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3622 ,  A61N1/3627 ,  A61N1/3684

摘要： Safety pacing in multi-site cardiac rhythm management (CRM) devices is provided. According to various method embodiments, a first cardiac signal from a first cardiac region and a second cardiac signal from a second cardiac region are sensed. The first cardiac region is paced to maintain at least a minimum cardiac rate, and the second cardiac region is paced to maintain at least the minimum cardiac rate when a pace in the first cardiac region is inhibited. Other aspects and embodiments are provided herein.

摘要翻译： 提供了多站点心律管理（CRM）设备中的安全起搏。 根据各种方法实施例，感测来自第一心脏区域的第一心脏信号和来自第二心脏区域的第二心脏信号。 第一心脏区域起搏以保持至少最小心率，并且当第一心脏区域中的步调被抑制时，第二心脏区域起搏以保持至少最小心率。 本文提供了其它方面和实施例。

公开(公告)号：US08751377B2

公开(公告)日：2014-06-10

申请号：US12790321

申请日：2010-05-28

申请人： Jeffrey H. Bierer ,  Andrew Kramer ,  Robert M. Mauldin ,  Thomas Myrick

发明人： Jeffrey H. Bierer ,  Andrew Kramer ,  Robert M. Mauldin ,  Thomas Myrick

IPC分类号： G06Q40/00

CPC分类号： G06Q40/02 ,  G06Q20/40 ,  G06Q40/00

摘要： A system and method for providing emergency reserve conditional credit to a customer of a financial institution. The emergency conditional credit may be provided to the customer in the form of a line-of-credit or a loan based on the occurrence of a predetermined condition, such as involuntary unemployment, disability or the like. The emergency reserve product of the present invention is a product that can be offered through a financial institution or other ER-providing entity and, as such, does not require the level of regulation required of an insurance product. The invention also provides for the emergency reserve product to be offered in conjunction with a debt cancellation feature, referred to as emergency reserve protection, which serves to cancel the outstanding debt associated with the loan or line-of-credit.

摘要翻译： 一种向金融机构的客户提供紧急储备条件信贷的制度和方法。 可以根据发生预定条件（如非自愿失业，残疾等）的信用额度或贷款形式向客户提供紧急有条件信贷。 本发明的紧急储备产品是可以通过金融机构或其他提供ER的实体提供的产品，因此不要求保险产品要求的规定级别。 本发明还规定了紧急储备产品与被称为紧急储备保护的债务抵免功能一起提供，用于取消与贷款或信用额度相关的未偿还债务。

公开(公告)号：US20070137655A1

公开(公告)日：2007-06-21

申请号：US11592637

申请日：2006-11-03

申请人： Joe Paraschac ,  Ryan Boucher ,  Edward Gillis ,  Octavian Iancea ,  Andrew Kramer ,  Brian McCollum ,  Scott McGill ,  Lionel Nelson ,  Andres Tomas

发明人： Joe Paraschac ,  Ryan Boucher ,  Edward Gillis ,  Octavian Iancea ,  Andrew Kramer ,  Brian McCollum ,  Scott McGill ,  Lionel Nelson ,  Andres Tomas

IPC分类号： A61F5/56

CPC分类号： A61F5/566 ,  A61F5/56 ,  Y10S602/902

摘要： Systems and methods are provided for resisting posterior movement of the tongue during sleep, thereby keeping an airway open. The systems and methods employ a first structure that can be placed either in or on a tongue within an oral cavity and/or in a region of hyoid muscle. The first structure includes a ferromagnetic material. The systems and methods employ a second structure that can be placed either in or on external tissue outside the oral cavity and/or in or on external tissue outside the oral cavity in a desired relationship with the first structure. The second structure includes a magnetic material that magnetically interacts with the ferromagnetic material by attracting the ferromagnetic material, thereby resisting posterior movement of the tongue.

摘要翻译： 提供了系统和方法，用于抵抗睡眠期间舌头的后运动，从而保持呼吸道畅通。 该系统和方法采用可以放置在口腔内和/或舌骨区域内或舌上的第一结构。 第一结构包括铁磁材料。 该系统和方法采用第二结构，该第二结构可以以与第一结构的期望的关系置于口腔外部和/或外部组织外部和/或外部组织中或外部组织中。 第二结构包括通过吸引铁磁材料与铁磁材料磁性相互作用的磁性材料，从而抵抗舌头的后部运动。

公开(公告)号：US20070135853A1

公开(公告)日：2007-06-14

申请号：US11673098

申请日：2007-02-09

申请人： Andrew Kramer ,  Jeffrey Stahmann

发明人： Andrew Kramer ,  Jeffrey Stahmann

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61N1/362 ,  A61N1/3621 ,  A61N1/3622 ,  A61N1/365 ,  A61N1/368 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3688 ,  A61N1/3702 ,  A61N1/395 ,  A61N1/3962 ,  A61N1/3987

摘要： A cardiac rhythm management device which employs pacing therapy to regularize the ventricular rhythm. Such ventricular rate regularization may be employed within bradycardia pacemakers, ventricular resynchronization devices, or implantable cardioverter/defibrillators.

摘要翻译： 一种心律管理装置，其采用起搏治疗来使心室节律正常化。 心动过速起搏器，心室再同步装置或植入式心律转复器/去纤颤器中可采用这种心室率正常化。

公开(公告)号：US20070016260A1

公开(公告)日：2007-01-18

申请号：US11522691

申请日：2006-09-18

申请人： Kenneth Baker ,  David Perschbacher ,  Andrew Kramer ,  Jeffrey Stahmann

发明人： Kenneth Baker ,  David Perschbacher ,  Andrew Kramer ,  Jeffrey Stahmann

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/3684

摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

摘要翻译： 通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

公开(公告)号：US20060259083A1

公开(公告)日：2006-11-16

申请号：US11125503

申请日：2005-05-10

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/36

CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/362 ,  A61N1/36514 ,  A61N1/36564 ,  A61N1/36592 ,  A61N1/3987

摘要： Various aspects relate to a method. In various embodiments, a therapy of a first therapy type is delivered, and it is identified whether a therapy of a second therapy type is present to affect the therapy of the first therapy type. Delivery of the therapy is controlled based on the presence of the therapy of the second therapy type. Some embodiments deliver the therapy of the first type using one set of parameters in the presence of a therapy of a second type, and deliver the therapy of the first type using another set of parameters when the therapy of the second type is not present. In various embodiments, one of the therapy types includes a cardiac rhythm management therapy, and the other includes a neural stimulation therapy. Other aspects and embodiments are provided herein.

公开(公告)号：US20060241699A1

公开(公告)日：2006-10-26

申请号：US11110542

申请日：2005-04-20

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/38

CPC分类号： A61N1/36114 ,  A61N1/3962

摘要： Various aspects of the present subject matter relate to a system. Various embodiments of the system comprise at least one port to connect to at least one lead with at least one electrode, at least one stimulator circuit and at least one controller. The at least one stimulator circuit is connected to the at least one port and is adapted to deliver neural stimulation to a neural stimulation target using the at least one electrode. The at least one controller is adapted to determine when another energy discharge other than the neural stimulation to the neural stimulation target is occurring and to prevent delivery of the neural stimulation simultaneously with the other energy discharge. Other aspects and embodiments are provided herein.

摘要翻译： 本主题的各个方面涉及系统。 系统的各种实施例包括至少一个端口，以连接至少一个引线与至少一个电极，至少一个刺激器电路和至少一个控制器。 所述至少一个刺激器电路连接到所述至少一个端口，并且适于使用所述至少一个电极将神经刺激递送到神经刺激靶。 所述至少一个控制器适于确定何时发生除了对神经刺激靶的神经刺激以外的其他能量放电，并且防止神经刺激与另一能量放电同时传送。 本文提供了其它方面和实施例。

公开(公告)号：US20060135998A1

公开(公告)日：2006-06-22

申请号：US11280940

申请日：2005-11-16

申请人： Imad Libbus ,  Andrew Kramer ,  Julia Moffitt

发明人： Imad Libbus ,  Andrew Kramer ,  Julia Moffitt

IPC分类号： A61N1/00

CPC分类号： A61N1/36053 ,  A61N1/36117

摘要： Various device embodiments comprise a pulse generator, a signal processing module and a controller. The pulse generator is adapted to provide a neural stimulation signal to be applied at a neural simulation site within an autonomic nervous system (ANS). The signal processing module is adapted to receive and process sensed neural traffic at a neural sensing site within the ANS. The controller is connected to the pulse generator and adapted to provide a neural stimulation control signal to the pulse generator to generate the neural stimulation signal, and to the signal processing module to receive a feedback control signal indicative of the sensed neural traffic. The controller is adapted to adjust the neural stimulation control signal to adjust at least one parameter of the neural stimulation signal to converge on desired sensed neural traffic at the neural sensing site. Other aspects and embodiments are provided herein.

摘要翻译： 各种装置实施例包括脉冲发生器，信号处理模块和控制器。 脉冲发生器适于提供要在自主神经系统（ANS）内神经模拟部位应用的神经刺激信号。 信号处理模块适于在ANS内的神经感测部位接收和处理感测到的神经流量。 控制器连接到脉冲发生器并且适于向脉冲发生器提供神经刺激控制信号以产生神经刺激信号，并且向信号处理模块接收指示所感测的神经流量的反馈控制信号。 控制器适于调整神经刺激控制信号以调整神经刺激信号的至少一个参数以收敛于神经感测位置处的期望感测的神经交通。 本文提供了其它方面和实施例。

公开(公告)号：US20060106428A1

公开(公告)日：2006-05-18

申请号：US10992320

申请日：2004-11-18

申请人： Imad Libbus ,  Andrew Kramer ,  Julia Moffitt

发明人： Imad Libbus ,  Andrew Kramer ,  Julia Moffitt

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61N1/36114 ,  A61N1/36117

摘要： Various aspects of the present subject matter relate to a device. In various embodiments, the device comprises at least one port adapted to connect at least one lead, a CRM functions module connected to the port and adapted to provide at least one CRM function using the lead, a neural function module, and a controller connected to the CRM functions module and the neural function module. The at least one CRM function includes a function to provide an electrical signal to the lead to capture cardiac tissue. The neural function module includes a signal processing module connected to the port and adapted to receive and process a nerve traffic signal from the lead into a signal indicative of the nerve traffic. The controller is adapted to implement a CRM therapy based on the signal indicative of the nerve traffic. Other aspects are provided herein.

摘要翻译： 本主题的各个方面涉及一种装置。 在各种实施例中，该装置包括适于连接至少一个引线，连接到端口的CRM功能模块和适于使用引线提供至少一个CRM功能的至少一个端口，神经功能模块和连接到 CRM功能模块和神经功能模块。 所述至少一个CRM功能包括向导线提供电信号以捕获心脏组织的功能。 所述神经功能模块包括连接到所述端口的信号处理模块，并适于接收并处理来自所述导线的神经交通信号并将其处理成指示神经流量的信号。 控制器适于基于指示神经流量的信号来实施CRM治疗。 本文提供了其他方面。