公开(公告)号：US20090030304A1

公开(公告)日：2009-01-29

申请号：US12219609

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61B5/055

CPC分类号： A61K49/0004 ,  A61B5/4064 ,  A61B5/4088 ,  A61B6/037 ,  A61B6/5247

摘要： A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.

摘要翻译： 公开了一种用于检测具有神经变性变化的脑区域以及患者脑部血管变化的脑区域的计算机化方法，以及适合于此的成像装置。 在至少一个实施例中，该方法包括通过正电子发射断层摄影和脑的第二数据记录经由磁共振成像记录脑的第一数据记录; 从第一数据记录重建PET图像和从第二数据记录重建MRI图像; 识别MRI图像中具有血管变化的脑区域的证据; 将MRI图像分割成灰质和白质; 识别PET图像中具有神经变性变化的脑区域; 并叠加PET图像和分割的MRI图像，以确定具有神经变性变化的脑区域是否存在于灰质物质或白质中，第一数据记录和第二数据记录的记录被快速连续进行而不重新定位 病人或甚至同时进行。

公开(公告)号：US20070055137A1

公开(公告)日：2007-03-08

申请号：US11510178

申请日：2006-08-25

申请人： Thorsten Feiweier

发明人： Thorsten Feiweier

IPC分类号： A61B5/05

CPC分类号： G01R33/5616 ,  G01R33/56554

摘要： In a method and MRT apparatus for reduction of Nyquist ghosts in medical magnetic resonance imaging given the application of EPI sequences of one or more progression curves with regard to one or more characterizing quantities of the EPI echo, is determined dependent on the echo number of a readout gradient pulse train defined by pulse shape, pulse amplitude and pulse duration, an EPI measurement is implemented with a readout gradient pulse train, composed of alternating positive and negative amplitudes with under which alternating positive and negative echoes and respectively readout, and a phase coding gradient, so a phase-coded data set is acquired, the phase-coded data set is corrected on the basis of the progression curves, and is Fourier-transformed the corrected data set, to obtain an artifact-reduced (with regard to the Nyquist ghosts) image data set.

摘要翻译： 在用于减少医学磁共振成像中奈奎斯特幽灵的方法和MRT装置中，鉴于EPI回波的一个或多个特征量的一个或多个进展曲线的EPI序列的应用，取决于一个 由脉冲形状，脉冲幅度和脉冲持续时间定义的读出梯度脉冲串，EPI测量由读出梯度脉冲串实现，读出梯度脉冲串由交替的正和负振幅组成，其下交替正负回波并分别读出和相位编码 梯度，因此获取相位编码数据集，基于进展曲线来校正相位编码数据集，并且对经校正的数据集进行傅立叶变换，以获得伪像（关于奈奎斯特 鬼）图像数据集。

公开(公告)号：US07002347B2

公开(公告)日：2006-02-21

申请号：US10953303

申请日：2004-09-29

申请人： Thorsten Feiweier ,  Razvan Lazar ,  Wolfgang Renz ,  Lothar Schön

发明人： Thorsten Feiweier ,  Razvan Lazar ,  Wolfgang Renz ,  Lothar Schön

IPC分类号： G01V3/00

CPC分类号： G01R33/341

摘要： A local coil unit for a magnetic resonance apparatus, which radiates a radio-frequency field into an examination subject, has a housing and at least a part of the housing is formed of an insulating dielectric material that passively compensates for an inhomogeneity in the high-frequency field in the subject. The material has a relative dielectric value εr of greater than 50, preferably greater than 100, and a dielectric loss factor tan δ of less than 2.5×10−2, preferably less than 1×10−3. In the dielectric material displacement currents are generated which create an additional magnetic field that compensates for the minima in the B1 field as a result of the eddy currents arising in the patient due to the radio-frequency radiation.

摘要翻译： 用于将射频场辐射到检查对象中的磁共振设备的局部线圈单元具有壳体，并且壳体的至少一部分由绝缘电介质材料形成，被动地补偿高频场中的不均匀性， 频率场。 该材料具有大于50，优选大于100的相对电介质值εL r以及低于2.5×10 -2的介电损耗因子tanδ，优​​选地较小 超过1×10 -3 -3。 在电介质材料中，产生位移电流，其产生额外的磁场，其由于射频辐射而在患者体内产生的涡流的结果来补偿B1场中的最小值。

公开(公告)号：US06734672B2

公开(公告)日：2004-05-11

申请号：US10425806

申请日：2003-04-29

申请人： Thorsten Feiweier

发明人： Thorsten Feiweier

IPC分类号： G01V300

CPC分类号： G01R33/3854

摘要： In a method for determining acoustic resonances in a magnetic resonance tomography system, a resonance measurement is implemented by applying a number of alternating gradient pulses that have a fixed time spacing relative to one another, applying an excitation pulse, and obtaining one or more MR signals, the MR signal of the resonance measurement is evaluated with respect to at least one parameter characterizing the acoustic resonance of the MRT system, the aforementioned steps are repeated with variation of the time spacing of the gradient pulses, a resonance curve is formed on the basis of the value of a characteristic parameter of the resonance measurement as function of the varied time spacing, and the resonance or resonances of the MRT system are determined from the resonance curve.

摘要翻译： 在用于确定磁共振断层摄影系统中的声共振的方法中，通过施加相对于彼此具有固定时间间隔的多个交替梯度脉冲来施加谐振测量，施加激励脉冲，并获得一个或多个MR信号 相对于表征MRT系统的声共振的至少一个参数来评估谐振测量的MR信号，通过梯度脉冲的时间间隔的变化重复上述步骤，基于此形成共振曲线 作为变化的时间间隔的函数的谐振测量的特性参数的值，并且共振曲线确定MRT系统的谐振或共振。

公开(公告)号：US10422844B2

公开(公告)日：2019-09-24

申请号：US15407141

申请日：2017-01-16

申请人： Thorsten Feiweier ,  Andreas Greiser ,  Uvo Hölscher ,  Thorsten Speckner ,  David Grodzki ,  Mathias Nittka ,  Daniel Nico Splitthoff

发明人： Thorsten Feiweier ,  Andreas Greiser ,  Uvo Hölscher ,  Thorsten Speckner ,  David Grodzki ,  Mathias Nittka ,  Daniel Nico Splitthoff

IPC分类号： G01V3/00 ,  G01R33/54 ,  G01R33/28 ,  G01R33/385

摘要： A method for setting a MRI sequence, a magnetic resonance device, and a computer program product are provided. The method includes providing, by a limitation unit, at least one limitation; providing, by a parameter provision unit, a plurality of parameters of the sequence, wherein at least one parameter of the plurality of parameters is assigned to a default parameter value; selecting, by a selection unit, a parameter of the plurality of parameters; determining, by a simulation unit, at least one sequential pattern based on at least one default parameter value of the default parameter values; determining, by an analysis unit, a permissible range of parameter values of the selected parameter based on at least one sequential pattern and the at least one limitation; and establishing, by an establishment unit, a new parameter value of the selected parameter within the permissible range of the parameter values.

公开(公告)号：US09636422B2

公开(公告)日：2017-05-02

申请号：US12219609

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Diana Martin ,  Günther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Thorsten Feiweier ,  Diana Martin ,  Günther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61K49/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/00

CPC分类号： A61K49/0004 ,  A61B5/4064 ,  A61B5/4088 ,  A61B6/037 ,  A61B6/5247

摘要： A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.

公开(公告)号：US09557248B2

公开(公告)日：2017-01-31

申请号：US14208375

申请日：2014-03-13

申请人： Thorsten Feiweier ,  Alto Stemmer

发明人： Thorsten Feiweier ,  Alto Stemmer

IPC分类号： G01M99/00 ,  G06F19/00 ,  G01R33/54 ,  G01R33/561 ,  A61B6/00 ,  A61B8/00

CPC分类号： G01M99/008 ,  A61B6/586 ,  A61B8/54 ,  G01R33/543 ,  G01R33/561 ,  G06F19/00 ,  G06F19/321 ,  G16H40/63

摘要： In a method for operating a medical imaging system and a medical imaging system operating according to such a method, a measurement sequence is divided into a number of partial sequences, with each of the partial sequences resulting in a loading of at least one of these system components when the measurement sequence is executed. The partial sequences are evaluated, in terms of their number and duration, using a computerized model in order to determine whether a load limit for the at least one of the system components is exceeded. If so, the number or duration of the partial sequences is modified, and a check using the computer model is again implemented. A number or respective duration of the partial sequences that results in the load limit not being exceeded is then used as a final output in order to operate the medical imaging system.

摘要翻译： 在用于操作根据这种方法操作的医学成像系统和医学成像系统的方法中，测量序列被分成多个部分序列，每个部分序列导致这些系统中的至少一个的加载 执行测量序列时的组件。 使用计算机化模型来评估部分序列的数量和持续时间，以便确定是否超过了至少一个系统组件的负载限制。 如果是这样，则部分序列的数量或持续时间被修改，并且再次实现使用计算机模型的检查。 然后将导致不超过负载限制的部分序列的数量或相应持续时间用作最终输出，以便操作医学成像系统。

公开(公告)号：US08638098B2

公开(公告)日：2014-01-28

申请号：US13231028

申请日：2011-09-13

申请人： Thorsten Feiweier

发明人： Thorsten Feiweier

IPC分类号： G01V3/00

CPC分类号： G01R33/56509 ,  G01R33/4828 ,  G01R33/485 ,  G01R33/56341 ,  G01R33/56366

摘要： In a magnetic resonance method and apparatus, a series of magnetic resonance exposures of an examination subject is generated by implementing multiple first measurements (data acquisitions) with variation of a measurement parameter from acquisition-to-acquisition, which strongly influences a contrast of the first material type excited in the first measurements, implementing multiple second measurements in which a second material type is essentially selectively imaged that is less contrast-dependent with regard to this measurement parameter in a processor calculating spatial correction values for image data of the first measurements based on spatial differences between image data of different second measurements, and, also in the processor, spatially correcting image data of the first measurements (Di) and/or registration of image data of different first measurements to one another on the basis of the correction values.

摘要翻译： 在磁共振方法和装置中，通过采集与获取之间的测量参数的变化实现多次第一测量（数据采集）来产生检查对象的一系列磁共振曝光，这强烈地影响第一 在第一测量中激发的材料类型，实现多个第二测量，其中基本上选择性地成像第二材料类型，其在处理器中对于该测量参数的对比度依赖性较小，该处理器基于第一测量结果计算第一测量的图像数据的空间校正值，基于 基于校正值，不同的第二测量的图像数据之间的空间差异，以及在处理器中，空间校正第一测量（Di）的图像数据和/或不同的第一测量的图像数据的对准。

公开(公告)号：US08548217B2

公开(公告)日：2013-10-01

申请号：US12874592

申请日：2010-09-02

申请人： Thorsten Feiweier ,  Stefan Huwer

发明人： Thorsten Feiweier ,  Stefan Huwer

IPC分类号： G06K9/00

CPC分类号： G01R33/56518 ,  A61B5/055 ,  A61B5/7207 ,  G01R33/56341

摘要： In a method for correction of distortions in image data in a diffusion imaging, the image data are acquired with an imaging MRT measurement for a predetermined diffusion weighting and map a predetermined image segment. A diffusion model for the image segment is determined. Output image data are determined for the image segment such that the output image data are essentially free of distortions caused by diffusion weighting. Reference image data are estimated for the predetermined diffusion weighting for the image segment based on the output image data and the diffusion model. The acquired image data are compared with the reference image data and the acquired image data are corrected based on the comparison.

摘要翻译： 在用于校正扩散成像中的图像数据中的失真的方法中，通过用于预定扩散加权的成像MRT测量获取图像数据并映射预定图像片段。 确定图像段的扩散模型。 为图像片段确定输出图像数据，使得输出图像数据基本上没有由扩散加权引起的失真。 基于输出图像数据和扩散模型，针对图像片段的预定扩散加权来估计参考图像数据。 将获取的图像数据与参考图像数据进行比较，并且基于比较来校正所获取的图像数据。

公开(公告)号：US20130127462A1

公开(公告)日：2013-05-23

申请号：US13679782

申请日：2012-11-16

申请人： Thorsten Feiweier ,  Thorsten Speckner

发明人： Thorsten Feiweier ,  Thorsten Speckner

IPC分类号： G01R33/48

CPC分类号： G01R33/48 ,  G01R33/3415 ,  G01R33/4835 ,  G01R33/543

摘要： A receiving device for magnetic resonance (MR) image signals of a body is operated in an MR system such that for at least one coil element of the receiving device, a space domain, in which a spatial sensitivity of the coil element satisfies a predetermined criterion, is determined. A center frequency and a bandwidth of the MR image signal radiated by the body in the space domain are determined for the space domain. A receive path disposed downstream of the coil element is parameterized for operation at the determined center frequency and with the determined bandwidth.

摘要翻译： 用于身体的磁共振（MR）图像信号的接收装置在MR系统中操作，使得对于接收装置的至少一个线圈元件，空间域，其中线圈元件的空间灵敏度满足预定标准 ， 决心，决意，决定。 空间域中的身体辐射的MR图像信号的中心频率和带宽被确定。 设置在线圈元件下游的接收路径被参数化以在确定的中心频率和确定的带宽下操作。