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    SYSTEM AND METHOD OF EVALUATING DOSE DELIVERED BY A RADIATION THERAPY SYSTEM
    31.
    发明申请
    SYSTEM AND METHOD OF EVALUATING DOSE DELIVERED BY A RADIATION THERAPY SYSTEM 有权
    用辐射治疗系统评估剂量的系统和方法

    公开(公告)号：US20070195929A1

    公开(公告)日：2007-08-23

    申请号：US11459097

    申请日：2006-07-21

    申请人： Kenneth Ruchala ,  Gustavo Olivera ,  Eric Schnarr ,  Weiguo Lu ,  Thomas Mackie

    发明人： Kenneth Ruchala ,  Gustavo Olivera ,  Eric Schnarr ,  Weiguo Lu ,  Thomas Mackie

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1048 ,  A61N5/1037 ,  A61N5/1038 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N5/1071 ,  A61N2005/1072

    摘要： A system and method of evaluating dose delivered by a radiation therapy system using a marker that indicates motion. The marker is associated with the patient. In one method of operation, the method includes delivering radiation to the patient, monitoring motion of the marker during the delivering radiation, and evaluating a dose delivered to the patient based at least in part on the motion of the marker. In another method of operation, the method includes delivering radiation to the patient, obtaining information relating to the delivery of radiation, estimating dose to the marker based at least in part on the information, acquiring dose received by the marker, and comparing the received dose with the estimated dose.

    摘要翻译： 一种评估使用指示运动的标记的放射治疗系统递送的剂量的系统和方法。 标记与患者相关联。 在一种操作方法中，该方法包括向患者传送辐射，监测在递送辐射期间标记物的运动，以及至少部分地基于标记物的运动评估递送给患者的剂量。 在另一种操作方法中，所述方法包括向患者传送辐射，获得与辐射传递相关的信息，至少部分地基于所述信息估计所述标记的剂量，获取由所述标记接收的剂量，以及将所述接收剂量 与估计剂量。

    Method for modification of radiotherapy treatment delivery
    37.
    发明申请
    Method for modification of radiotherapy treatment delivery 有权
    放射治疗传递的修改方法

    公开(公告)号：US20050201516A1

    公开(公告)日：2005-09-15

    申请号：US10506866

    申请日：2003-03-06

    申请人： Kenneth Ruchala ,  Gustavo Olivera ,  Jeffrey Kapatoes ,  Paul Reckwerdt ,  Weiguo Lu ,  John Hughes

    发明人： Kenneth Ruchala ,  Gustavo Olivera ,  Jeffrey Kapatoes ,  Paul Reckwerdt ,  Weiguo Lu ,  John Hughes

    IPC分类号： A61N20060101 ,  A61N1/00 ,  A61N5/10 ,  G06T1/00

    CPC分类号： A61N5/103 ,  A61N5/1038 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1069 ,  A61N2005/1061 ,  G06F19/00

    摘要： The present invention provides a novel method of contoured-anatomy dose repositioning (CADR) as a means to automatically reposition a patient to better recover the planned dose distribution without reoptimize the treatment plan. Specifically, CADR utilizes planning CT images, the planned dose distribution, and on-line images for repositioning dose distribution on a given day. Contours are also placed upon the images using manual, automatic, template-based, or other techniques. CADR then optimizes the rigid-body repositioning of the patient so that the daily dose distribution closely matches the planned dose distribution. The present invention also provides a method of multiple-margin optimization with daily selection (MMODS) to improve radiation delivery without reoptimization. During the initial optimization procedure, plans are optimized for several margins of various contours (e.g., tight, medium, loose, etc.), or with different objectives (e.g., aggressive treatment, sensitive structure sparing, etc.). Similarly, if multiple patient image sets are available, plans can be optimized for the different anatomical layouts, either using current information, or accumulated information regarding the superposition of organ locations in the combination of images. A user can then choose in real time from a variety of optimized plans, generally with different margins, during the treatment process, and thereby compensate for a recognized change in size or position of the tumor or neighboring tissue.

    摘要翻译： 本发明提供了一种轮廓解剖学剂量重新定位（CADR）的新方法，作为自动重新定位患者的手段，以更好地恢复计划的剂量分布，而不重新优化治疗计划。 具体来说，CADR利用计划的CT图像，计划的剂量分布和在线图像在给定的一天重新定位剂量分布。 使用手动，自动，基于模板或其他技术的轮廓也被放置在图像上。 然后，CADR优化患者的刚体重新定位，使得日剂量分布与计划的剂量分布密切相关。 本发明还提供了一种利用日常选择（MMODS）进行多边距优化的方法，以改善辐射递送而不重新优化。 在初始优化过程中，针对各种轮廓（例如紧密，中等，松散等）或不同目标（例如，积极的治疗，敏感的结构节省等）的几个边缘优化了计划。 类似地，如果多个患者图像组可用，则针对不同的解剖结构布局可以优化计划，使用当前信息或关于图像组合中器官位置的叠加的累积信息。 然后，用户可以在处理过程中从各种优化的计划（通常具有不同的边缘）实时地选择，从而补偿肿瘤或相邻组织的大小或位置的公认变化。

    Image registration using fourier phase matching
    38.
    发明授权
    Image registration using fourier phase matching 失效
    图像配准使用傅立叶相位匹配

    公开(公告)号：US06373970B1

    公开(公告)日：2002-04-16

    申请号：US09221729

    申请日：1998-12-29

    申请人： Fang Dong ,  Weiguo Lu

    发明人： Fang Dong ,  Weiguo Lu

    IPC分类号： G06K900

    CPC分类号： G06K9/6203 ,  G06K9/32 ,  G06T7/37 ,  G06T2207/30004 ,  Y10S128/922 ,  Y10S128/923

    摘要： A method and an apparatus for registering frames of imaging data using Fourier phase matching. Successive image frames of pixel data are processed using an image registration algorithm. Either image frames or the frames after edge detection are transformed into polar-logarithmic coordinates in the frequency domain and the phases of the Fourier transform of the resulting image representations, after inverse Fast Fourier transformation, are matched. The coordinates at the maximum phase difference are used to determine the scaling and rotation parameters needed for image frame registration. The frequency domain representation of one of the image frames is then scaled and rotated using an anti-aliasing algorithm in accordance with those parameters. The phase of the result is matched with the phase of the frequency domain representation of the other image frame to determine the translation parameters needed for image frame registration.

    摘要翻译： 一种使用傅立叶相位匹配来记录成像数据帧的方法和装置。 使用图像配准算法处理像素数据的连续图像帧。 将图像帧或边缘检测后的帧转换为频域中的极对数坐标，并且在快速傅里叶逆变换之后的所得图像表示的傅立叶变换的相位匹配。 最大相位差处的坐标用于确定图像帧配准所需的缩放和旋转参数。 然后使用根据这些参数的抗混叠算法对图像帧之一的频域表示进行缩放和旋转。 结果的相位与其他图像帧的频域表示的相位匹配，以确定图像帧注册所需的平移参数。