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公开(公告)号：US09468754B2
公开(公告)日：2016-10-18
申请号：US12474645
申请日：2009-05-29
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , A61B5/042 , A61N1/0534 , A61N1/0541 , A61N1/056
摘要： Selective sensing implantable medical leads include pulsing and sensing portions and pulsing and not sensing portion. Leads and electrodes may be used in defibrillation and as integrated bipolar defibrillation electrodes. An entire electrode can pass charge while a valve metal or valve metal oxide portion of the electrode prevents the entire electrode from sensing, effectively rejecting unwanted signals. Differential conduction pathways, due to the valve metal and/or oxides thereof, cause the portions of the electrodes to conduct differently when used anodically and cathodically. Complex intracardiac electrical gradient can be formed along with a number of virtual electrodes within the tissue. Reentrant loops can thereby be pinned following defibrillation shock.
摘要翻译： 选择性感测可植入医疗引线包括脉冲和感测部分以及脉冲和不感测部分。 引线和电极可用于除颤和作为集成的双极除颤电极。 整个电极可以通过电荷，同时电极的阀金属或阀金属氧化物部分防止整个电极感测，有效地排除不需要的信号。 由于阀门金属和/或其氧化物导致的差动传导路径导致当阳极和阴极使用时，电极的部分不同地传导。 可以与组织内的多个虚拟电极一起形成复杂的心内电梯度。 因此，除颤休克后可以固定可重入环。
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公开(公告)号：US08831748B2
公开(公告)日：2014-09-09
申请号：US12414265
申请日：2009-03-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , Y10T29/49117
摘要： A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.
摘要翻译： 医疗电极包括位于引线主体上方的细长导电线圈和与引线主体接触并位于细长导电线圈的各个线圈之间的导电聚合物材料。 在某些实施方案中，导电聚合物是注入导电填料（例如炭黑）的聚合物（例如硅酮）。 在某些实施例中，导电聚合物材料通常是等距的，细长导电线圈的各个线圈的外径。 通过在引线体的长度上滑动细长导电线圈来制造医用电极，将导电聚合物分散在螺旋线圈上，将管插入细长导电线圈上，将聚合物材料分布在细长导电线圈 ，加热管道，使管道围绕细长的导电线圈收缩，并取出管道。
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33.发明授权公开(公告)号：US08538523B2
公开(公告)日：2013-09-17
申请号：US13616300
申请日：2012-09-14
申请人： John L. Sommer , David Wayne Bourn , Mark T. Marshall , Michael D. Eggen , Gabriela C. Miyazawa
发明人： John L. Sommer , David Wayne Bourn , Mark T. Marshall , Michael D. Eggen , Gabriela C. Miyazawa
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/056 , A61N1/36114 , A61N1/36185 , A61N1/3684 , A61N1/3686 , A61N2001/0585
摘要： A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.
摘要翻译： 医疗系统包括多个电极; 至少一个传感器被配置为基于患者的至少一个生理参数输出至少一个信号; 和处理器。 处理器被配置为使用多个电极配置来控制对患者的刺激递送。 每个电极配置包括多个电极中的至少一个。 对于每个电极配置，处理器被配置为基于信号来确定目标组织对刺激的第一响应，以及基于该信号来确定非目标组织对刺激的第二响应。 处理器还被配置为基于电极配置的第一和第二响应来选择用于将刺激递送到患者的电极配置中的至少一个。 作为示例，靶组织可以是左心室或迷走神经。
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公开(公告)号：US07933662B2
公开(公告)日：2011-04-26
申请号：US11380259
申请日：2006-04-26
IPC分类号： A61N1/04
CPC分类号： A61N1/16 , A61N1/0573 , A61N1/086
摘要： A medical electrical lead includes an inductance augmenter assembly. The assembly includes an inductor coil formed of an insulated wire, which is wound about a non-conductive core and is electrically coupled in series between a conductor coil of the lead and an electrode of the lead.
摘要翻译： 医用电线包括电感增强器组件。 组件包括由绝缘电线形成的电感线圈，其缠绕在非导电芯上并且串联地电连接在引线的导体线圈和引线的电极之间。
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公开(公告)号：US20100030147A1
公开(公告)日：2010-02-04
申请号：US12431926
申请日：2009-04-29
IPC分类号： A61M5/42
CPC分类号： A61B17/3468 , A61B17/3462 , A61B17/3472 , A61B2017/00026 , A61B2017/0003 , A61B2017/00561 , A61B2017/306 , A61B2017/320044 , A61B2017/320056 , A61M5/425 , A61M5/427 , A61M2005/1586 , A61N1/046 , A61N1/0504
摘要： An apparatus for guiding the placement of a subcutaneous device that includes a strap having an indentation configured for a fold of skin and fat layer to be positioned within the indentation as the subcutaneous device is advanced to a desired implantation site.
摘要翻译： 一种用于引导皮下装置的放置的装置，所述装置包括当皮下装置前进到期望的植入部位时，所述带具有构造成用于皮肤和脂肪层折叠的凹陷，以定位在凹陷内。
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公开(公告)号：US6066166A
公开(公告)日：2000-05-23
申请号：US143504
申请日：1998-08-28
IPC分类号： A61N1/05
CPC分类号： A61N1/0563
摘要： An implantable cardioversion/defibrillation lead having an elongated insulative lead body carrying a tip electrode located at its distal end and a cardioversion/defibrillation electrode located on the lead body, proximal to the tip electrode. An elongated conductor coupled to the tip electrode extends proximally within the lead body. At the proximal end of the lead body is a first connector assembly carrying a first connector and a second connector assembly carrying a second connector. An elongated, stranded or cabled conductor is coupled to the cardioversion/defibrillation electrode and to the second connector and extends uninterrupted therebetween. A cylindrical transition member is coupled to the first connector by means of a coiled conductor. A press-fit sleeve having a longitudinal lumen extending therethrough compresses the stranded or conductor between the press-fit sleeve and the transition member to provide electrical interconnection between the stranded or cabled conductor and the transition member.
摘要翻译： 植入式心脏复律/除颤引线，其具有承载位于其远端的尖端电极的细长绝缘引线体和位于所述引线主体上的靠近所述尖端电极的心脏复律/除颤电极。 耦合到尖端电极的细长导体在引线体内向近侧延伸。 在引线体的近端处是承载第一连接器的第一连接器组件和承载第二连接器的第二连接器组件。 细长的，绞合的或有线的导体耦合到心脏复律/除颤电极和第二连接器并且在它们之间不间断地延伸。 圆柱形过渡构件通过线圈导体连接到第一连接器。 具有延伸通过其延伸的纵向内腔的压入套筒压缩压配合套筒和过渡构件之间的绞合或导体，以提供绞合或电缆导体与过渡构件之间的电互连。
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公开(公告)号：US09126037B2
公开(公告)日：2015-09-08
申请号：US13093115
申请日：2011-04-25
CPC分类号： A61N1/16 , A61N1/0573 , A61N1/086
摘要： A medical electrical lead includes an inductance augmenter assembly. The assembly includes an inductor coil formed of an insulated wire, which is wound about a non-conductive core and is electrically coupled in series between a conductor coil of the lead and an electrode of the lead.
摘要翻译： 医用电线包括电感增强器组件。 组件包括由绝缘电线形成的电感线圈，其缠绕在非导电芯上并且串联地电连接在引线的导体线圈和引线的电极之间。
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公开(公告)号：US08103357B2
公开(公告)日：2012-01-24
申请号：US11854627
申请日：2007-09-13
IPC分类号： A61N1/00
CPC分类号： A61B5/0215 , A61N1/056
摘要： An implantable medical lead includes an adaptor coupled to a body of the lead. The adaptor holds a sensor capsule between a first portion and a second portion of the lead body.
摘要翻译： 可植入医疗引线包括耦合到引线主体的适配器。 适配器将传感器囊保持在引线主体的第一部分和第二部分之间。
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公开(公告)号：US20100305675A1
公开(公告)日：2010-12-02
申请号：US12474645
申请日：2009-05-29
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , A61B5/042 , A61N1/0534 , A61N1/0541 , A61N1/056
摘要： Selective sensing implantable medical leads include pulsing and sensing portions and pulsing and not sensing portion. Leads and electrodes may be used in defibrillation and as integrated bipolar defibrillation electrodes. An entire electrode can pass charge while a valve metal or valve metal oxide portion of the electrode prevents the entire electrode from sensing, effectively rejecting unwanted signals. Differential conduction pathways, due to the valve metal and/or oxides thereof, cause the portions of the electrodes to conduct differently when used anodically and cathodically. Complex intracardiac electrical gradient can be formed along with a number of virtual electrodes within the tissue. Reentrant loops can thereby be pinned following defibrillation shock.
摘要翻译： 选择性感测可植入医疗引线包括脉冲和感测部分以及脉冲和不感测部分。 引线和电极可用于除颤和作为集成的双极除颤电极。 整个电极可以通过电荷，同时电极的阀金属或阀金属氧化物部分防止整个电极感测，有效地排除不需要的信号。 由于阀门金属和/或其氧化物导致的差动传导路径导致当阳极和阴极使用时，电极的部分不同地传导。 可以与组织内的多个虚拟电极一起形成复杂的心内电梯度。 因此，除颤休克后可以固定可重入环。
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公开(公告)号：US20090259282A1
公开(公告)日：2009-10-15
申请号：US12423428
申请日：2009-04-14
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N1/056
摘要： An extendable medical lead comprises a lead body and a sheath defining a cavity that encloses a length of the lead body. The length of the lead body enclosed within the sheath may be coiled or otherwise gathered such that when extended, the length of the enclosed section of the lead body is greater than the length of the sheath. The sheath may include a seal to help prevent contaminant entry into the cavity in order to help reduce tissue in growth around the length of the lead body disposed within the sheath. A portion of the length of the lead body enclosed within the sheath exits the cavity through an aperture defined by the seal when a tensile force is applied to the lead body.
摘要翻译： 可延伸的医用引线包括引线主体和限定封闭引线主体长度的空腔的护套。 封装在护套内的引线体的长度可以被卷绕或以其他方式聚集，使得当延伸时，引线主体的封闭部分的长度大于护套的长度。 护套可以包括密封件，以帮助防止污染物进入空腔，以帮助减少围绕设置在护套内的引线体的长度周围的组织的生长。 封闭在护套内的引线主体长度的一部分，当拉力施加到引线主体上时，通过由密封件限定的孔隙离开空腔。
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