公开(公告)号：US07223417B2

公开(公告)日：2007-05-29

申请号：US10421093

申请日：2003-04-23

申请人： Gary J. Calton ,  Louis L. Wood

发明人： Gary J. Calton ,  Louis L. Wood

IPC分类号： A61K47/00 ,  A61K31/70 ,  A23L1/00

CPC分类号： A61K31/731 ,  A23L33/17 ,  A23L33/175 ,  A23V2002/00 ,  A23V2250/50366 ,  A23V2250/06 ,  A23V2250/044 ,  A23V2250/2482 ,  A23V2250/0606 ,  A23V2250/264 ,  A23V2250/6406 ,  A23V2250/032

摘要： Nutrient formulations are provided having a high content of carrageenan and a low liquid content. The nutrient formulation also contains at least one nutritional and/or pharmaceutical component such as flavorings, sweeteners, amino acids, fruit solids, protein and carbohydrates. The formulations are produced by mixing at least one carrageenan at a minimum of 5% by weight, and the desired nutritional and/or pharmaceutical component with no more than 50% by weight of a liquid.

摘要翻译： 提供具有高含量角叉菜胶和低液体含量的营养制剂。 营养成分还含有至少一种营养和/或药物组分，例如调味剂，甜味剂，氨基酸，水果固体，蛋白质和碳水化合物。 通过将至少一种至少5重量％的角叉菜聚糖和所需的营养和/或药物组分与不超过50重量％的液体混合来制备制剂。

公开(公告)号：US5833972A

公开(公告)日：1998-11-10

申请号：US911948

申请日：1997-08-15

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： A61F13/15 ,  A01N37/18 ,  A61F13/472 ,  A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/11 ,  A61K8/41 ,  A61K8/49 ,  A61K8/66 ,  A61K8/88 ,  A61L9/00 ,  A61L9/01 ,  A61L9/04 ,  A61L11/00 ,  A61L15/46 ,  A61Q15/00 ,  A01N25/12

CPC分类号： A61Q15/00 ,  A61K8/0208 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/4913 ,  A61K8/88 ,  A61L15/46 ,  A61K2800/622 ,  A61L2300/204

摘要： Imides reduce odors. Imides are especially efficient at reducing the odors of odoriferous an amine or ammonia. The imides may be incorporated in pads which are the recipients of odoriferous waste materials, dispersed in holding tanks or lagoons or dispersed over human and animal wastes. Polysuccinimide, copolymers of polysuccinimide, polyglutarimide and mixtures thereof are especially useful for the reduction of odors, especially of ammonia and an amine.

公开(公告)号：US5708126A

公开(公告)日：1998-01-13

申请号：US421485

申请日：1995-04-13

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C08G69/00 ,  C08G69/10 ,  C08G69/36 ,  C08G73/02 ,  C08G73/10 ,  C11D3/37 ,  C08G73/00

CPC分类号： C08G69/00 ,  C08G69/10 ,  C08G69/36 ,  C08G73/02 ,  C08G73/1092 ,  C11D3/3719

摘要： Copolymers of polyaspartic acid which are suitable for the inhibition of scale deposition were obtained by reacting maleic acid, an additional polycarboxylic acid and ammonia in a stoichiometric excess, at 120.degree.-350.degree. C., preferably 180.degree.-300.degree. C., to provide copolymers of polysuccinimide. In a second embodiment, a polyamine was added to the reaction mix. These intermediate polysuccinimide copolymers could then be converted to the salts of copolymers of polyaspartic acid by hydrolysis with a hydroxide. Such copolymers are useful in preventing deposition of scale from water and find applications in treating water. Other applications include scale prevention additives for detergents. In addition, such copolymers inhibit dental tartar and plaque formation.

摘要翻译： 通过使马来酸，额外的多元羧酸和化学计量过量的氨在120-350℃，优选180-300℃反应，得到适用于抑制垢沉积的聚天冬氨酸的共聚物，得到 提供聚琥珀酰亚胺的共聚物。 在第二个实施方案中，将多胺加入到反应混合物中。 然后可以用氢氧化物水解将这些中间体聚琥珀酰亚胺共聚物转化成聚天冬氨酸的共聚物的盐。 这种共聚物可用于防止水垢沉积，并用于处理水。 其他应用包括用于洗涤剂的防垢添加剂。 此外，这种共聚物抑制牙垢和斑块形成。

公开(公告)号：US5688904A

公开(公告)日：1997-11-18

申请号：US724417

申请日：1996-10-01

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C08G69/10 ,  C08G73/10

CPC分类号： C08G73/1092

摘要： Polysuccinimide, polyaspartic acid and salts of polyaspartic acid may be prepared by means of heating aspartic acid in the presence of sodium bisulfate. The molecular weight of the polymers may be increased from that obtained without the use of sodium bisulfate. The polysuccinimide, polyaspartic acid or salt of polyaspartic acid obtained have low color. Polyaspartic acid may be obtained in this manner directly from the effluent of an immobilized cell or enzyme column which catalyzes the production of L-aspartic acid without the necessity of intermediate isolation steps.

摘要翻译： 聚琥珀酰亚胺，聚天冬氨酸和聚天冬氨酸的盐可以通过在硫酸氢钠存在下加热天冬氨酸来制备。 聚合物的分子量可以从不使用硫酸氢钠获得的分子量增加。 得到的聚琥珀酰亚胺，聚天冬氨酸或聚天冬氨酸的盐具有低的颜色。 聚天冬氨酸可以直接从催化L-天冬氨酸生产的固定化细胞或酶柱的流出物获得，而不需要中间分离步骤。

公开(公告)号：US5610264A

公开(公告)日：1997-03-11

申请号：US559049

申请日：1995-11-16

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C08G73/10 ,  C08G69/10 ,  C08G63/44

CPC分类号： C08G73/1092

摘要： Polysuccinimide, polyaspartic acid and salts of polyaspartic acid may be prepared by means of heating aspartic acid in the presence of sodium bisulfate. The molecular weight of the polymers may be increased from that obtained without the use of sodium bisulfate. The polysuccinimide, polyaspartic acid or salt of polyaspartic acid obtained have low color. Polyaspartic acid may be obtained in this manner directly from the effluent of an immobilized cell or enzyme column which catalyzes the production of L-aspartic acid without the necessity of intermediate isolation steps.

摘要翻译： 聚琥珀酰亚胺，聚天冬氨酸和聚天冬氨酸的盐可以通过在硫酸氢钠存在下加热天冬氨酸来制备。 聚合物的分子量可以从不使用硫酸氢钠获得的分子量增加。 得到的聚琥珀酰亚胺，聚天冬氨酸或聚天冬氨酸的盐具有低的颜色。 聚天冬氨酸可以直接从催化L-天冬氨酸生产的固定化细胞或酶柱的流出物获得，而不需要中间分离步骤。

公开(公告)号：US5587146A

公开(公告)日：1996-12-24

申请号：US421482

申请日：1995-04-13

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C08G69/00 ,  C08G69/10 ,  C08G69/36 ,  C08G73/02 ,  C08G73/10 ,  C11D3/37 ,  A61K7/16 ,  A61K7/22

CPC分类号： C08G69/00 ,  C08G69/10 ,  C08G69/36 ,  C08G73/02 ,  C08G73/1092 ,  C11D3/3719

摘要： Copolymers of polyaspartic acid which are suitable for the inhibition of scale deposition were obtained by reacting maleic acid, an additional polycarboxylic acid and ammonia in a stoichiometric excess, at 120.degree.-350.degree. C., preferably 180.degree.-300.degree. C., to provide copolymers of polysuccinimide. In a second embodiment, a polyamine was added to the reaction mix. These intermediate polysuccinimide copolymers could then be converted to the salts of copolymers of polyaspartic acid by hydrolysis with a hydroxide.Such copolymers are useful in preventing deposition of scale from water and find applications in treating water. Other applications include scale prevention additives for detergents. In addition, such copolymers inhibit dental tartar and plaque formation.

摘要翻译： 通过使马来酸，额外的多元羧酸和化学计量过量的氨在120-350℃，优选180-300℃反应，得到适用于抑制垢沉积的聚天冬氨酸的共聚物，得到 提供聚琥珀酰亚胺的共聚物。 在第二个实施方案中，将多胺加入到反应混合物中。 然后可以用氢氧化物水解将这些中间体聚琥珀酰亚胺共聚物转化成聚天冬氨酸的共聚物的盐。 这种共聚物可用于防止水垢沉积，并用于处理水。 其他应用包括用于洗涤剂的防垢添加剂。 此外，这种共聚物抑制牙垢和斑块形成。

公开(公告)号：US5527878A

公开(公告)日：1996-06-18

申请号：US445343

申请日：1995-05-19

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： A61K8/00 ,  A61K8/64 ,  A61K8/88 ,  A61Q11/00 ,  C08G69/00 ,  C08G69/10 ,  C08G69/48 ,  C08G73/10 ,  C08L77/00 ,  C08L77/04 ,  C09K3/00

CPC分类号： C08G69/00 ,  A61K8/88 ,  A61Q11/00 ,  C08G73/1092

摘要： Polymers of maleic, fumaric or malic acids or maleic, fumaric or malic acid and ammonia with amino acids are prepared by heating at 180.degree.-350.degree. C., preferably 200.degree.-300.degree. C. The polymer formed may be converted to a salt by hydrolysis with a metal hydroxide or ammonium hydroxide.

公开(公告)号：US5442038A

公开(公告)日：1995-08-15

申请号：US132246

申请日：1993-10-06

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： A61K8/81 ,  A61K8/88 ,  A61Q11/00 ,  C08G69/00 ,  C08G73/06 ,  C08G73/10 ,  C11D3/37

CPC分类号： C11D3/3719 ,  A61K8/8164 ,  A61K8/88 ,  A61Q11/00 ,  C08G69/00 ,  C08G73/0611 ,  C08G73/1092

摘要： Polymers of maleic acid may be prepared by thermally polymerizing malic acid, maleic acid or fumaric acid with less than one equivalent of ammonia. The polymers are modified by the incorporation of amines, carboxylic acids or combinations thereof. The polymers formed are excellent inhibitors of alkaline earth salt deposition, dispersants, tartar control additives, detergent additives, and water treatment agents.

摘要翻译： 马来酸的聚合物可以通过用少于1当量的氨将苹果酸，马来酸或富马酸热聚合来制备。 通过引入胺，羧酸或其组合来改性聚合物。 形成的聚合物是碱土盐沉积的优异抑制剂，分散剂，牙垢控制添加剂，洗涤剂添加剂和水处理剂。

公开(公告)号：US5389303A

公开(公告)日：1995-02-14

申请号：US118588

申请日：1993-09-10

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C11D7/22 ,  C02F5/10 ,  C02F5/12 ,  C08G69/10 ,  C08G73/10 ,  C11D3/20 ,  C11D3/37 ,  C11D7/26 ,  C11D7/32 ,  C11D1/10 ,  C11D3/33

CPC分类号： C11D3/3719 ,  C02F5/10 ,  C02F5/12 ,  C08G69/10 ,  C08G73/1092 ,  C11D3/2086

摘要： Polyamino acids or their salts mixed with citric acid or its salts, in a ratio of 75:25 to 0.1:99.9, polyamino acid or its salt to citric acid or its salts, and especially in a ratio of 1:1 to 1:99 polyamino acids or their salts to citric acid or its salts, provide a much higher rate of chelation of calcium ion than expected on the basis of the addition of the polyamino acid to citric acid. Such mixtures may be used in high volume water applications such as boiler, cooling, oil well, agricultural sprays and irrigation water. They are also useful in preventing scale formation on fabrics when formulated with laundry detergents and in preventing scale formation on glassware when formulated in dishwashing detergents.

摘要翻译： 将聚氨基酸或其盐与柠檬酸或其盐以75:25至0.1:99.9的比例混合，聚氨基酸或其盐与柠檬酸或其盐，特别是1:1至1:99的比例混合 聚氨基酸或其盐与柠檬酸或其盐相比，基于将聚氨基酸加入到柠檬酸中提供比预期更高的钙离子螯合速率。 这种混合物可用于大量水分应用中，例如锅炉，冷却，油井，农用喷雾和灌溉水。 它们也可用于防止在用洗衣洗涤剂配制时在织物上形成水垢，并且在配制在餐具洗涤剂中时防止玻璃器皿上的结垢形成。

公开(公告)号：US5306429A

公开(公告)日：1994-04-26

申请号：US968319

申请日：1992-10-29

申请人： Louis L. Wood ,  Gary J. Calton

发明人： Louis L. Wood ,  Gary J. Calton

IPC分类号： C02F5/00 ,  C02F5/10 ,  C02F5/12 ,  C08G73/10 ,  C11D3/37

CPC分类号： C08G73/1092 ,  C02F5/12 ,  C11D3/3719

摘要： Copolymers of polyamino acids formed by reaction of polysuccinimide with alkyl, alkenyl, aromatic amines or alkyl and alkenyl polyamines are useful as inhibitors of mineral scale deposition. Such compounds may be used in high volume water applications such as boiler, cooling, oil well, agricultural sprays and irrigation water. They are also useful in preventing scale formation on fabrics when formulated with laundry detergents and in preventing scale formation on glassware when formulated in dishwashing detergents.

摘要翻译： 通过聚琥珀酰亚胺与烷基，烯基，芳香胺或烷基和烯基多胺的反应形成的聚氨基酸的共聚物可用作矿物垢沉积的抑制剂。 这种化合物可以用于大量水的应用中，例如锅炉，冷却，油井，农用喷雾和灌溉水。 它们也可用于防止在用洗衣洗涤剂配制时在织物上形成水垢，并且在配制在餐具洗涤剂中时防止玻璃器皿上的结垢形成。