公开(公告)号：US20120021300A1

公开(公告)日：2012-01-26

申请号：US13057035

申请日：2009-08-04

申请人： Koji Abe ,  Masahide Kondo

发明人： Koji Abe ,  Masahide Kondo

IPC分类号： H01M10/056

CPC分类号： H01M10/0567 ,  H01M6/166 ,  H01M6/168 ,  H01M10/052 ,  H01M10/0568 ,  H01M10/0569 ,  H01M2300/0042 ,  Y02E60/12 ,  Y02T10/7011

摘要： A nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, containing a hydantoin compound represented by the following general formula (I) in an amount of from 0.01 to 5% by mass of the nonaqueous electrolytic solution, and excellent in battery characteristics such as high-temperature storage property and cycle property. (In the formula, R1 and R2 each represent a methyl group or an ethyl group; R3 and R4 each represent a hydrogen atom, a methyl group or an ethyl group.)

摘要翻译： 溶解在非水溶剂中的电解质盐的非水电解液含有由以下通式（I）表示的乙内酰脲化合物，其量为非水电解液的0.01〜5质量％，电池特性优异 作为高温储存性能和循环性能。 （式中，R 1和R 2各自表示甲基或乙基; R 3和R 4各自表示氢原子，甲基或乙基。）

公开(公告)号：US5986062A

公开(公告)日：1999-11-16

申请号：US538471

申请日：1995-10-03

申请人： Takao Ohmura ,  Akinori Sumi ,  Wataru Ohtani ,  Naoto Furuhata ,  Kazuya Takeshima ,  Kaeko Kamide ,  Munehiro Noda ,  Masahide Kondo ,  Syoichi Ishikawa ,  Kazuhiro Oohara ,  Kazumasa Yokoyama ,  Nagatoshi Fujiwara

发明人： Takao Ohmura ,  Akinori Sumi ,  Wataru Ohtani ,  Naoto Furuhata ,  Kazuya Takeshima ,  Kaeko Kamide ,  Munehiro Noda ,  Masahide Kondo ,  Syoichi Ishikawa ,  Kazuhiro Oohara ,  Kazumasa Yokoyama ,  Nagatoshi Fujiwara

IPC分类号： A61K38/00 ,  C07K14/765

CPC分类号： C07K14/765 ,  A61K2039/545 ,  A61K38/00

摘要： Human serum albumin obtained by gene manipulation techniques can be purified by a combination of specified steps in which a culture supernatant obtained from a human serum albumin-producing host is subjected to ultrafiltration, heat treatment, acid treatment and another ultrafiltration, followed by subsequent treatments with a cation exchanger, a hydrophobic chromatography carrier and an anion exchanger, and by salting-out to thereby obtain a pure form of human serum albumin which contains substantially no proteinous and polysaccharide contaminants, which is formulated into a pharmaceutical preparation. The thus obtained human serum albumin can further be purified by treating recombinant human serum albumin with a hydrophobic chromatography carrier at pH of 2 to 5 and a salt concentration of 0.4 to 1 and exposing the carrier to a pH of 6 to 8 and a salt concentration of 0.01 to 0.3 M, or treating the culture supernatant with boric acid or a salt thereof at pH 8 to 11 for 1 to 10 hours and recovering the supernatant. This process makes it possible to effeciently purify recombinant human serum albumin and to provide substantially pure human serum albumin which does not contain producer host-related substances and other contaminants and is sufficiently free from coloration.

摘要翻译： 通过基因操作技术获得的人血清白蛋白可以通过特定步骤的组合来纯化，其中将得自人血清白蛋白的宿主的培养上清液进行超滤，热处理，酸处理和另一次超滤，然后用 阳离子交换剂，疏水性色谱载体和阴离子交换剂，并通过盐析，从而获得纯的形式的人血清白蛋白，其基本上不含有配制成药物制剂的蛋白质和多糖污染物。 由此获得的人血清白蛋白可以进一步通过用pH为2至5和盐浓度为0.4至1的疏水色谱载体处理重组人血清白蛋白并将载体暴露于pH6至8和盐浓度 为0.01〜0.3M，或用硼酸或其盐在pH8〜11处理培养上清1〜10小时，回收上清液。 该方法使得可以有效地纯化重组人血清白蛋白并提供基本上纯的人血清白蛋白，其不含生产者宿主相关物质和其它污染物，并且没有着色。

公开(公告)号：US4841113A

公开(公告)日：1989-06-20

申请号：US259828

申请日：1988-10-19

申请人： Akio Hamada ,  Gen Tsujii ,  Genzo Fuse ,  Masahide Kondo

发明人： Akio Hamada ,  Gen Tsujii ,  Genzo Fuse ,  Masahide Kondo

IPC分类号： B23K11/11 ,  B23K11/25 ,  B23K11/31

CPC分类号： B23K11/253 ,  B23K11/115 ,  B23K11/314

摘要： A welding control apparatus and a method for controlling thereof for automatic welding machines having a welding gun successively moved by a robot to a plurality of welding spots on a work object for welding is disclosed. The welding control apparatus and the method for controlling thereof detect any abnormal conditions for preventing damages to the gun or undesired occurrence of holes in the work object.

摘要翻译： 公开了一种焊接控制装置及其控制方法，该自动焊接机具有由机器人连续移动到焊接工件上的多个焊接点的焊枪。 焊接控制装置及其控制方法检测任何异常情况，以防止对枪的损坏或工作物体中不希望有的孔的出现。