公开(公告)号：US20150225708A1

公开(公告)日：2015-08-13

申请号：US14696979

申请日：2015-04-27

Applicant: NOVOZYMES A/S

Inventor： Carsten Andersen ,  Thomas Agersten Poulsen

IPC: C12N9/26 ,  C11D3/386 ,  C12P7/14

CPC classification number: C12N9/2417 ,  C11D3/386 ,  C11D3/38681 ,  C12N9/2414 ,  C12N15/8257 ,  C12P7/06 ,  C12P7/14 ,  C12P19/02 ,  C12P19/04 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01001 ,  Y02E50/17

Abstract: The present invention relates to alpha-amylases, nucleic acids encoding the alpha-amylases, methods of producing the alpha-amylases, and methods of using the alpha-amylases.

Abstract translation: 本发明涉及α-淀粉酶，编码α-淀粉酶的核酸，α-淀粉酶的生产方法和使用α-淀粉酶的方法。

公开(公告)号：US20150218545A1

公开(公告)日：2015-08-06

申请号：US14690937

申请日：2015-04-20

Applicant: NOVOZYMES A/S

Inventor： Tomoko Matsui ,  Allan Noergaard ,  Thomas Agersten Poulsen ,  John Matthews

IPC: C12N9/58 ,  C12P7/06

CPC classification number: C12N9/58 ,  C12P7/06 ,  C12Y304/24 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to proteases having at least 75% identity to a protease derived from Thermoascus aurantiacus and comprises at least one modification in the amino acid sequence thereof. These protease variants have improved thermostability. The invention also relates to DNA encoding these proteases, methods of their production, as well as the use thereof.

Abstract translation: 本发明涉及与衍生自嗜热嗜铬鱼的蛋白酶具有至少75％同一性的蛋白酶，并且包含其氨基酸序列中的至少一个修饰。 这些蛋白酶变体具有改善的热稳定性。 本发明还涉及编码这些蛋白酶的DNA，其生产方法及其用途。

公开(公告)号：US20130203126A1

公开(公告)日：2013-08-08

申请号：US13857431

申请日：2013-04-05

Applicant: NOVOZYMES A/S

Inventor： Carsten Andersen ,  Thomas Agersten Poulsen

IPC: C12N9/24

CPC classification number: C12N9/2417 ,  C11D3/386 ,  C11D3/38681 ,  C12N9/2414 ,  C12N15/8257 ,  C12P7/06 ,  C12P7/14 ,  C12P19/02 ,  C12P19/04 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01001 ,  Y02E50/17

Abstract: The present invention relates to alpha-amylases, nucleic acids encoding the alpha-amylases, methods of producing the alpha-amylases, and methods of using the alpha-amylases.

Abstract translation: 本发明涉及α-淀粉酶，编码α-淀粉酶的核酸，α-淀粉酶的生产方法和使用α-淀粉酶的方法。

公开(公告)号：US12252720B2

公开(公告)日：2025-03-18

申请号：US18165023

申请日：2023-02-06

Applicant: Novozymes A/S ,  Novozymes North America, Inc.

Inventor： Carsten Andersen ,  Randall Deinhammer ,  Thomas Agersten Poulsen ,  Miguel Duarte Toscano ,  Peter Kamp Hansen ,  Henrik Friis-Madsen ,  Anders Viksoe-Nielsen ,  Signe Eskildsen Larsen ,  Lars L. H. Christensen

IPC: C12N9/28 ,  C11D3/386 ,  C12N9/26 ,  C12N15/82 ,  C12P7/06 ,  C12P7/14 ,  C12P19/02 ,  C12P19/04 ,  C12P19/14

Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.

公开(公告)号：US11661592B2

公开(公告)日：2023-05-30

申请号：US17041631

申请日：2019-04-12

Applicant: Novozymes A/S

Inventor： Svend Gunnar Kaasgaard ,  Frank Winther Rasmussen ,  Roland Alexander Pache ,  Lars Anderson ,  Mette Louise Dissing Overgaard ,  Thomas Agersten Poulsen ,  Lars Giger

IPC: C12N9/42 ,  C11D3/386 ,  C12N9/50 ,  C12N15/80

CPC classification number: C12N9/2437 ,  C11D3/38618 ,  C11D3/38645 ,  C12N9/50 ,  C12N15/80 ,  C12Y302/01004

Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.

公开(公告)号：US11566239B2

公开(公告)日：2023-01-31

申请号：US17041588

申请日：2019-04-12

Applicant: Novozymes A/S

Inventor： Svend Gunnar Kaasgaard ,  Frank Winther Rasmussen ,  Roland Alexander Pache ,  Lars Anderson ,  Mette Louise Dissing Overgaard ,  Thomas Agersten Poulsen ,  Dorte Marie Koefoed Klitgaard ,  Christian Isak Joergensen ,  Lars Giger

IPC: C12N9/42 ,  C11D3/386

Abstract: Disclosed is variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.

公开(公告)号：US11332725B2

公开(公告)日：2022-05-17

申请号：US16645914

申请日：2018-09-25

Applicant: Novozymes A/S

Inventor： Miguel Duarte Guilherme Pereira Toscano ,  Thomas Agersten Poulsen ,  Carsten Horslev Hansen ,  Lone Baunsgaard ,  Keith Gibson

IPC: C12N9/20 ,  C11D3/386

Abstract: The present invention relates to variants of a parent lipase which has lipase activity and comprise one or more substitutions corresponding to G23S, D27N, A40I, F51I,L, E56R, D57N, V60E,K, K98I, N101D, R118F, G163S, T231R, N233R, Y220F, T244E, and P256T using SEQ ID NO: 2 for numbering. The present invention also relates to compositions or microcapsule compositions comprising a lipase variant of the invention and to liquid products comprising a microcapsule composition of the invention as well as the use of said microcapsule composition for stabilizing lipase variants of the invention.

公开(公告)号：US20220145273A1

公开(公告)日：2022-05-12

申请号：US17583269

申请日：2022-01-25

Applicant: Novozymes A/S

Inventor： Christian Lundager Gylstorff ,  Christian Jackel ,  Jesper Vind ,  Allan Svendsen ,  Marco Malten ,  Thomas Agersten Poulsen

IPC: C12N9/20 ,  C11D3/386

Abstract: The present invention relates to a variant of a parent lipase, which parent lipase has the amino acid sequence of SEQ ID NO: 2, wherein the variant has lipase activity, comprises a substitution at a position corresponding to position 51 and comprises a substitution or remains unaltered at a position corresponding to position 96 of SEQ ID NO: 2. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US11312946B2

公开(公告)日：2022-04-26

申请号：US16423866

申请日：2019-05-28

Applicant: NOVOZYMES A/S

Inventor： Marco Malten ,  Kim Borch ,  Lise Munch Mikkelsen ,  Thomas Agersten Poulsen ,  Luise Erlandsen ,  Hanne Philbert Nielsen ,  Carsten Horslev Hansen ,  Allan Svendsen ,  Christian Lundager Gylstorff ,  Jesper Vind ,  Christian Jackel

IPC: C12N9/20 ,  C12N9/18 ,  C11D17/04 ,  C11D3/386 ,  B65D65/46 ,  A61K8/66

Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.

公开(公告)号：US20210363510A1

公开(公告)日：2021-11-25

申请号：US17041588

申请日：2019-04-12

Applicant: Novozymes A/S

Inventor： Svend Gunnar Kaasgaard ,  Frank Winther Rasmussen ,  Roland Alexander Pache ,  Lars Anderson ,  Mette Louise Dissing Overgaard ,  Thomas Agersten Poulsen ,  Dorte Marie Koefoed Klitgaard ,  Christian Isak Joergensen ,  Lars Giger

IPC: C12N9/42 ,  C11D3/386

Abstract: Disclosed is variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.