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公开(公告)号：US11312946B2
公开(公告)日：2022-04-26
申请号：US16423866
申请日：2019-05-28
Applicant: NOVOZYMES A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.-
公开(公告)号：US20210024857A1
公开(公告)日：2021-01-28
申请号：US17039395
申请日：2020-09-30
Applicant: Novozymes A/S
Inventor： Ole Simonsen , Carsten Hoerslev Hansen , Luise Erlandsen
Abstract: Enzymes tend to be inactivated during wash by a bleach catalyst in combination with a source of organic peroxyacids. The risk of enzyme inactivation by active bleach catalyst is reduced when the release of the enzyme into the wash solution is delayed. The enzyme stability during washing together with a bleach catalyst can be improved by applying a delayed-release coating to cores which comprise the enzyme.
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公开(公告)号：US10119128B2
公开(公告)日：2018-11-06
申请号：US15177879
申请日：2016-06-09
Applicant: NOVOZYMES A/S
Inventor： Luise Erlandsen , Carsten Hoerslev Hansen , Jesper Vind , Allan Svendsen , Carsten Peter Sonksen
Abstract: The present invention relates to lipase variants and methods of obtaining them. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号：US20170306269A1
公开(公告)日：2017-10-26
申请号：US15513435
申请日：2015-09-28
Applicant: Novozymes A/S
Inventor： Carsten Hoerslev Hansen , Jesper Vind , Luise Erlandsen , Bitten Plesner , Anna Catharina Olsen Stenholm
CPC classification number: C11D3/386 , C11D3/38627 , C11D3/38681 , C11D3/392 , C12N9/00 , C12N9/16 , C12N9/20 , C12Y301/00
Abstract: The present invention relates to lipase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号：US20130337111A1
公开(公告)日：2013-12-19
申请号：US13964166
申请日：2013-08-12
Applicant: Novozymes A/S
Inventor： Christel Thea Jorgensen , Luise Erlandsen , Lone Dybdal Nilsson , Kim Borch , Jesper Vind
CPC classification number: A21D8/042 , C12Q1/44 , G01N2333/918
Abstract: Lipolytic enzymes which improve the properties of dough or baked products generally have a high activity towards lipids which are capable of forming a hexagonal phase, and a screening method was developed on this basis. The improved properties may include a larger loaf volume, an improved shape factor, an improved crumb structure, reduced dough stickiness, improved dough stability and/or improved tolerance towards extended proofing.
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Patent Agency Ranking
公开(公告)号：US20190284541A1
公开(公告)日：2019-09-19
申请号：US16423866
申请日：2019-05-28
Applicant: NOVOZYMES A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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公开(公告)号：US10351833B2
公开(公告)日：2019-07-16
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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公开(公告)号：US09394530B2
公开(公告)日：2016-07-19
申请号：US14372858
申请日：2013-01-25
Applicant: Novozymes A/S
Inventor： Luise Erlandsen , Carsten Hoerslev Hansen , Jesper Vind , Allan Svendsen , Carsten Peter Sonksen
CPC classification number: C12N9/20 , C11D3/38627 , C11D3/392 , C12N9/18 , C12Y301/01
Abstract: The present invention relates to lipase variants and methods of obtaining them. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Abstract translation: 本发明涉及脂肪酶变体及其获得方法。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。
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公开(公告)号：US20160076012A1
公开(公告)日：2016-03-17
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Glystorff , Jesper Vind , Christian Jackel
CPC classification number: C12N9/18 , A61K8/66 , B65D65/46 , C11D3/38627 , C11D17/042 , C11D17/043 , C12N9/20 , C12Y301/01 , C12Y301/01003
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
Abstract translation: 本发明涉及包含变体具有脂肪酶活性的母体脂肪酶的变体的洗涤剂组合物与SEQ ID NO：2具有至少60％但小于100％的序列同一性，并且包括在对应于T231R + N233R的位置和 SEQ ID NO：2的D96E，D111A，D254S，G163K，P256T，G91T和G38A的至少一个或多个（例如数个）。本发明还涉及组合物的用途， 清洁方法 本发明还涉及编码变体的变体和多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞。
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公开(公告)号：US20130045302A1
公开(公告)日：2013-02-21
申请号：US13658930
申请日：2012-10-24
Applicant: NOVOZYMES A/S
Inventor： Christel Thea Jorgensen , Luise Erlandsen , Lone Dybdal Nilsson , Kim Borch , Jesper Vind
CPC classification number: A21D8/042 , C12Q1/44 , G01N2333/918
Abstract: Lipolytic enzymes which improve the properties of dough or baked products generally have a high activity towards lipids which are capable of forming a hexagonal phase, and a screening method was developed on this basis. The improved properties may include a larger loaf volume, an improved shape factor, an improved crumb structure, reduced dough stickiness, improved dough stability and/or improved tolerance towards extended proofing.
Abstract translation: 改善面团或烘焙产品性质的脂肪分解酶通常对能够形成六方相的脂质具有高活性，并且在此基础上开发了筛选方法。 改进的性能可以包括更大的面包体积，改进的形状因子，改进的面包屑结构，减少的面团粘性，改善的面团稳定性和/或改进的对延伸打样的耐受性。
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