摘要:
A process for producing 1-bromo-4-phenylbutane of the formula (1): ##STR1## which is characterized by the steps of; reacting 4-bromobutyryl halide of the formula (2): ##STR2## where X is a halogen atom, with benzene in the presence of a Lewis acid to give a 4-bromobutyrophenone of the formula (3): ##STR3## and reacting 4-bromobutyrophenone compound of the formula (3) with hydrogen in the presence of a metal catalyst.
摘要:
There is disclosed a process for producing hexahydrothieno[3,4-d]imidazole-2,4-diones of the formula (1): wherein R is the same or different and represents a lower alkyl group, an alkenyl group, an aryl group or an aralkyl group all of which may be substituted, which is characterized by the step of reacting hexahydrofuro[3,4-d]imidazole-2,4-diones of the formula (2): ##STR1## wherein R has the same meaning as described above with hydrogen sulfide in the presence of a basic compound and sulfur.
摘要:
A process for producing an aminonitropyridine represented by the general formula [1], which comprises reacting a nitropyridine represented by the general formula [2] (wherein X.sup.1, X.sup.2 and X.sup.3 indicate a hydrogen atom, a halogen atom, a nitro group, a cyano group, an aryl group, an aromatic heterocycle or an alkyl group, etc.; Y is an oxygen atom; and n is 0 or 1) with an O-substituted hydroxylamine represented by the general formula [3] (wherein R.sup.4 is a hydrogen atom, an alkyl group, a cycloalkyl group or an aralkyl group; and R.sup.5 is an alkyl group or an aralkyl group) or a salt thereof in the presence of a base and a metal catalyst. ##STR1##
摘要:
An object of the present invention is to industrially advantageously produce N-nitroisoureas or a salt thereof which is useful as a synthetic intermediate for pharmaceuticals and pesticides. The present invention relates to a process for producing a compound represented by the formula (2): wherein R1, R2 and R3 are as defined below, or a salt thereof, which comprises reacting a compound represented by the formula (1): wherein R1 represents an optionally substituted straight-chain or branched C1 to C6 alkyl group, R2 and R3 are the same or different and represent an optionally substituted straight-chain or branched C1 to C6 alkyl group, a cycloalkyl group or a substituted aryl group, or R2 and R3 simultaneously represent a hydrogen atom, or a salt thereof with a nitrating agent in the presence of sulfur trioxide.
摘要:
There are disclosed a disulfone compound of formula (1): wherein Ar denotes an aryl group that may have a substituent, R1 denotes a hydrogen atom or a protective group of a hydroxyl group and the wavy line means that the disulfone compound is an E or Z geometrical isomer or a mixture thereof, a method for producing the same, intermediate compounds therefore and a process for producing retinol through the disulfone compound.
摘要:
There are provided a dihalogen derivative represented by formula (2): wherein X represents a halogen atom and R2 represents a protective group for a hydroxyl group; a process for producing the same; and a process for producing vitamin A by use of said dihalogen derivative.
摘要:
There is provided a ketosulfone derivative represented by the formula (I): wherein Ar represents an aryl group which may be substituted, and R1′ and R2′ represent a hydrogen atom or a protective group of a hydroxyl group and processes for producing the same.
摘要:
There are disclosed: a hydroxyaldehyde derivative of formula (1): wherein the wavy line depicted by indicates a single bond and the compound having a double bond to which said single bond is attached represents E or Z isomer or a mixture thereof, a methoxy alcohol derivative of formula (2): wherein the wavy line depicted by indicates a single bond and the compound having a double bond to which said single bond is attached represents E or Z isomer or a mixture thereof, processes for producing the same, and a process for producing a retinal using the same.
摘要:
There is provided a method for producing arylvinylsulfone of the formula: ##STR1## wherein, R.sup.1 and R.sup.2 denote each independently a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group,a nitro group, an amino group, a lower alkylamino group anda lower di(alkylamino) group,which comprises reacting .beta.-haloethylarylsulfone of the formula: ##STR2## wherein, R.sup.1 and R.sup.2 are as defined above and X denotes a halogen atom, with an alkali metal carbonate or an alkali metal hydrogencarbonate in the presence of a catalytic amount of an amine or its inorganic acid salt or a quaternary ammonium salt.
摘要:
There is disclosed a process for the production of 2-thiophene aldehydes, in which the 2-thiophene aldehydes are obtained by the formylation of thiophene or derivatives thereof with formamides and phosgene.