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公开(公告)号：US20220213561A1
公开(公告)日：2022-07-07
申请号：US17692469
申请日：2022-03-11
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
IPC: C12Q1/6886 , G06N7/00 , G06N20/00 , G16B15/00 , G16B20/00 , G16B20/10 , G16B20/20 , G16B25/00 , G16B40/00 , G16B40/20 , G16H10/40 , G16H50/20 , G16Z99/00 , C12Q1/6869
Abstract: The invention provides methods, systems, and computer readable medium for detecting ploidy of chromosome segments or entire chromosomes, for detecting single nucleotide variants and for detecting both ploidy of chromosome segments and single nucleotide variants. In some aspects, the invention provides methods, systems, and computer readable medium for detecting cancer or a chromosomal abnormality in a gestating fetus.
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公开(公告)号：US20210198743A1
公开(公告)日：2021-07-01
申请号：US17196722
申请日：2021-03-09
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
IPC: C12Q1/6883 , C12Q1/6811 , C12Q1/6848 , C12Q1/6809 , C12Q1/6851 , C12Q1/6844 , C12Q1/6869 , C12Q1/6855 , C12Q1/6874
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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Patent Agency Ranking
公开(公告)号：US20200157629A1
公开(公告)日：2020-05-21
申请号：US16777700
申请日：2020-01-30
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
IPC: C12Q1/6883 , C12Q1/6811 , C12Q1/6848 , C12Q1/6809 , C12Q1/6851 , C12Q1/6855 , C12Q1/6874
Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
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公开(公告)号：US20190211406A1
公开(公告)日：2019-07-11
申请号：US16359917
申请日：2019-03-20
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
IPC: C12Q1/6886 , G16B40/00 , G16B25/00 , G16B15/00 , G06N20/00 , G06N7/00 , G16H50/20 , G16H10/40 , C12Q1/6869
CPC classification number: C12Q1/6886 , C12Q1/6869 , C12Q2539/10 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172 , G06F19/00 , G06N7/005 , G06N20/00 , G16B15/00 , G16B25/00 , G16B40/00 , G16H10/40 , G16H50/20
Abstract: The invention provides methods, systems, and computer readable medium for detecting ploidy of chromosome segments or entire chromosomes, for detecting single nucleotide variants and for detecting both ploidy of chromosome segments and single nucleotide variants. In some aspects, the invention provides methods, systems, and computer readable medium for detecting cancer or a chromosomal abnormality in a gestating fetus.
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公开(公告)号：US20190211402A1
公开(公告)日：2019-07-11
申请号：US16288462
申请日：2019-02-28
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
IPC: C12Q1/6886 , G16B40/00 , G16B25/00 , G16B15/00 , G06N20/00 , G06N7/00 , G16H50/20 , G16H10/40 , C12Q1/6869
CPC classification number: C12Q1/6886 , C12Q1/6869 , C12Q2539/10 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172 , G06F19/00 , G06N7/005 , G06N20/00 , G16B15/00 , G16B25/00 , G16B40/00 , G16H10/40 , G16H50/20
Abstract: The invention provides methods, systems, and computer readable medium for detecting ploidy of chromosome segments or entire chromosomes, for detecting single nucleotide variants and for detecting both ploidy of chromosome segments and single nucleotide variants. In some aspects, the invention provides methods, systems, and computer readable medium for detecting cancer or a chromosomal abnormality in a gestating fetus.
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公开(公告)号：US20190106751A1
公开(公告)日：2019-04-11
申请号：US16092436
申请日：2017-04-17
Applicant: Natera, Inc. , UCL BUSINESS PLC
Inventor： Bernhard ZIMMERMANN , Tudor Pompiliu CONSTANTIN , Raheleh SALARI , Huseyin Eser KIRKIZLAR , Robert Charles SWANTON , Mariam JAMAL-HANJANI , Christopher ABBOSH , Gareth WILSON
IPC: C12Q1/6886 , C12Q1/6858
Abstract: The invention provides methods for detecting single nucleotide variants in lung cancer, especially stage 3a lung adenocarcinoma and lung squamous cell carcinoma. Additional methods and compositions, such as reaction mixtures and solid supports comprising clonal populations of nucleic acids, are provided.
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公开(公告)号：US20180171420A1
公开(公告)日：2018-06-21
申请号：US15898145
申请日：2018-02-15
Applicant: Natera, Inc.
Inventor： Joshua BABIARZ , Tudor Pompiliu CONSTANTIN , Lane A. EUBANK , George GEMELOS , Matthew Micah HILL , Huseyin Eser KIRKIZLAR , Matthew RABINOWITZ , Onur SAKARYA , Styrmir SIGURJONSSON , Bernhard ZIMMERMANN
CPC classification number: C12Q1/6886 , C12Q1/6869 , C12Q2539/10 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172 , G06F19/00 , G06N7/005 , G06N20/00 , G16B15/00 , G16B25/00 , G16B40/00 , G16H10/40 , G16H50/20
Abstract: The invention provides methods, systems, and computer readable medium for detecting ploidy of chromosome segments or entire chromosomes, for detecting single nucleotide variants and for detecting both ploidy of chromosome segments and single nucleotide variants. In some aspects, the invention provides methods, systems, and computer readable medium for detecting cancer or a chromosomal abnormality in a gestating fetus.
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