公开(公告)号：US20140037046A1

公开(公告)日：2014-02-06

申请号：US14112047

申请日：2012-04-17

申请人： Michael Grass ,  Holger Schmitt

发明人： Michael Grass ,  Holger Schmitt

IPC分类号： A61B6/00

CPC分类号： A61B6/481 ,  A61B6/00 ,  A61B6/486 ,  A61B6/503 ,  A61B6/507 ,  A61B6/5217 ,  A61B6/542 ,  A61B6/545 ,  F04C2270/0421

摘要： A method includes scanning a region of interest, during a contrast agent based perfusion scan, at a predetermined temporal sampling rate during contrast agent uptake in the region of interest, and generating time frame data indicative of the scanned region of interest. The method further includes identifying a predetermined change in an amount of the contrast agent in the region of interest from the time frame data. The method further includes scanning the region of interest at a lower temporal sampling rate, which is lower than the temporal sampling rate during the contrast agent uptake, in response to identifying the predetermined change in the amount of the contrast agent in the region of interest.

摘要翻译： 一种方法包括在造影剂基于灌注扫描期间以感兴趣区域中造影剂摄取期间的预定时间采样率扫描感兴趣区域，以及生成指示所扫描的感兴趣区域的时间帧数据。 所述方法还包括从所述时间帧数据中识别所述感兴趣区域中的造影剂的量的预定变化。 该方法还包括响应于识别感兴趣区域中的造影剂的量的预定变化，以较低的时间采样速率扫描感兴趣区域，其低于造影剂摄取期间的时间采样率。

公开(公告)号：US20130251286A1

公开(公告)日：2013-09-26

申请号：US13990450

申请日：2011-11-25

申请人： Bernhard Johannes Brendel ,  Thomas Koehler ,  Holger Schmitt ,  Rolf Dieter Bippus ,  Roland Proksa

发明人： Bernhard Johannes Brendel ,  Thomas Koehler ,  Holger Schmitt ,  Rolf Dieter Bippus ,  Roland Proksa

IPC分类号： G06T11/00

CPC分类号： G06T11/003 ,  G06T11/006 ,  G06T2211/424

摘要： A method includes reconstructing measured projection data using an iterative statistical reconstruction algorithm that reduces image artifact caused by differences in variances in projections of the measured projection data used to update a voxel of the image for one or more voxels of the image. A reconstructor includes a processor that reconstructs measured projection data using an iterative statistical reconstruction algorithm that reduces or mitigates image artifact caused by differences in variances in projections used to update a voxel of the image for one or more voxels of the image. A computer readable storage medium encoded with computer executable instructions, which, when executed by a processor of a computer, cause the processor to: reduce image artifact caused by differences in variances in projections used to update a voxel of an image for one or more voxels of the image using an iterative statistical reconstruction algorithm.

摘要翻译： 一种方法包括使用迭代统计重建算法来重建测量的投影数据，所述迭代统计重构算法减少由用于更新图像的一个或多个体素的图像的体素的测量投影数据的投影方差的差异引起的图像伪像。 重构器包括使用迭代统计重建算法来重建测量的投影数据的处理器，其减少或减轻由用于更新图像的一个或多个体素的图像的体素的投影方差的差异引起的图像伪像。 一种用计算机可执行指令编码的计算机可读存储介质，其在由计算机的处理器执行时使处理器能够：减少由用于更新一个或多个体素的图像的体素的投影差异的差异引起的图像伪像 的图像使用迭代统计重建算法。

公开(公告)号：US20080192997A1

公开(公告)日：2008-08-14

申请号：US11910477

申请日：2006-04-03

申请人： Michael Grass ,  Holger Schmitt

发明人： Michael Grass ,  Holger Schmitt

IPC分类号： G06K9/00

CPC分类号： G06T11/008 ,  G06T2211/404 ,  G06T2211/412

摘要： The present invention relates to image processing device (5) for generating a time series of 3D volume images showing the blood flow in a vascular tree of an object (40), based on a first series of X-ray projection images (D) of the object acquired from different projection directions and a second and a third series of X-ray projections images (E, F) of the object acquired alternately at a first or second fixed projection plane, respectively, during inflow of contrast agent into the vascular tree of the object. In order to allow image reconstruction of unambiguous structures in the object of interest, and, in particular, the generation of 3D volume images showing the blood flow in a vascular tree of an object even if that vascular tree comprises non-tubular structures, such as aneurysms, an image processing device is proposed comprising: a reconstruction unit (51) for reconstruction of a 3D volume image of said object from said first series of X-ray projection images (D), a segmentation unit (52) for segmentation of the vessel tree from said 3D volume image, —a forward projection unit (54) for forward projection of the segmented vessel tree onto said first and projection plane (R1, R2), respectively, and a mapping unit (55) for mapping of the image values of pixels of the vessel tree in said second and third, respectively, series of X-ray projection images onto corresponding voxels of said 3D volume image to obtain said time series of 3D volume images showing the blood flow in the vascular tree of the object.

摘要翻译： 本发明涉及一种图像处理装置（5），用于基于第一系列X射线投影图像（D）产生示出物体（40）的血管树中的血流的3D体积图像的时间序列， 在造影剂流入维管束期间，分别在第一或第二固定投影平面上交替地获取的物体从不同的投影方向获取的物体和第二和第三系列的X射线投影图像（E，F） 的对象。 为了允许感兴趣对象中的明确结构的图像重建，并且特别地，生成显示血液流在物体的血管树中的3D体积图像，即使该血管树包括非管状结构，例如 动脉瘤，提出了一种图像处理装置，包括：重建单元（51），用于从所述第一系列X射线投影图像（D）重建所述物体的3D体积图像，分割单元（52），用于分割 所述3D体积图像的容器树， - 用于将分割的血管树向前投影到所述第一和投影平面（R 1，R 2）上的前向投影单元（54） ）和映射单元（55），用于将所述第二和第三分支X射线投影图像中的血管树的像素的图像值映射到所述3D体积图像的相应体素上，以获得所述时间 系列3D体积图像显示 血液中血液流动的物体血管。

公开(公告)号：US20060293579A1

公开(公告)日：2006-12-28

申请号：US10553770

申请日：2004-04-21

申请人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

发明人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

IPC分类号： A61B5/05 ,  A61B6/00

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/504

摘要： The invention relates to an X-ray imaging device for visualizing the blood flow in a coronary vascular tree of a patient. According to the invention a first set (1) of X-ray projection images of the vascular tree is recorded during various phases of the heart cycle with simultaneous recording of the ECG (2) of the patient. By means of a suitable program control, computer means (17) of the device according to the invention a reconstruction then follows of the three-dimensional structure of the vascular tree during the various phases of the heart cycle. The invention proposes, to determine the time-dependent concentration of contrast agent within the reconstructed three-dimensional structure of the vascular tree, that local image areas within the X-ray projection images of the second set (6) assigned to individual vascular segments (5, 8) are located in accordance with the spatial positions of the vascular segments (5, 8) in the relevant phase of the heart cycle. The concentration of contrast agent in the area of the vascular segments (5, 8) is then determined by evaluation of the X-ray absorption within the local image areas found.

摘要翻译： 本发明涉及用于使患者的冠状动脉血管树中的血流可视化的X射线成像装置。 根据本发明，在心脏周期的各个阶段记录血管树的X射线投影图像的第一组（1），同时记录患者的ECG（2）。 通过合适的程序控制，根据本发明的装置的计算机装置（17）在心脏周期的各个阶段期间重建血管树的三维结构。 本发明提出，为了确定造影剂在血管树的重建三维结构内的时间依赖性浓度，将第二组（6）的X射线投影图像内的局部图像区域分配给各个血管节段 5,8）根据心脏周期的相关阶段中血管段（5,8）的空间位置来定位。 然后通过评估所发现的局部图像区域内的X射线吸收来确定血管片段（5,8）区域中造影剂的浓度。

公开(公告)号：US09468974B2

公开(公告)日：2016-10-18

申请号：US13318521

申请日：2010-05-05

申请人： Holger Schmitt ,  Thomas Enghof ,  Daniel Meister

发明人： Holger Schmitt ,  Thomas Enghof ,  Daniel Meister

IPC分类号： C22C9/00 ,  F16C33/06 ,  B32B15/01 ,  C22C32/00 ,  B22F7/08 ,  C22C1/04 ,  F16C33/12

CPC分类号： B22F7/08 ,  B32B15/015 ,  C22C1/0425 ,  C22C9/00 ,  C22C32/0089 ,  F16C33/121 ,  F16C2204/10

摘要： CuFe2P is used in a plain bearing or as a plain bearing material. A plain bearing composite material which comprises a supporting layer is provided with a bearing metal layer based on CuFe2P.

摘要翻译： CuFe2P用于滑动轴承或滑动轴承材料。 包括支撑层的滑动轴承复合材料设置有基于CuFe 2 P的支承金属层。

公开(公告)号：US09439606B2

公开(公告)日：2016-09-13

申请号：US13992421

申请日：2011-11-25

申请人： Holger Schmitt ,  Michael Grass

发明人： Holger Schmitt ,  Michael Grass

IPC分类号： A61B6/03 ,  A61B6/00 ,  A61B5/00 ,  A61B5/055 ,  A61B8/08 ,  A61B8/00 ,  A61B6/12 ,  A61M25/01 ,  A61M25/00

CPC分类号： A61B6/032 ,  A61B5/0084 ,  A61B5/055 ,  A61B5/742 ,  A61B6/037 ,  A61B6/12 ,  A61B6/4423 ,  A61B6/463 ,  A61B6/542 ,  A61B6/547 ,  A61B8/0841 ,  A61B8/463 ,  A61B34/20 ,  A61B90/98 ,  A61B2034/2055 ,  A61B2034/2059 ,  A61B2034/2065 ,  A61B2090/3945 ,  A61M25/0108 ,  A61M25/0113 ,  A61M25/0127 ,  A61M2025/0008 ,  A61M2025/0166

摘要： A system (100) includes an interventional apparatus (102) and an imaging scanner (101). The interventional apparatus includes a interventional instrument (204) configured to perform an image-guided interventional procedure for a patient. The interventional apparatus includes a position detector (122) that detects a position of the interventional instrument within a region of the patient at which the image-guided interventional procedure is performed from outside of the region of interest and generates a signal indicative of the detected position. The imaging scanner includes a controller (114) that activates the imaging scanner to scan the region of interest and the interventional instrument therein for one or more data acquisition cycles based on the movement signal.

摘要翻译： 系统（100）包括介入装置（102）和成像扫描器（101）。 介入装置包括被配置为对患者执行图像引导介入手术的介入器械（204）。 介入装置包括位置检测器（122），其检测介入器械在患者的区域内的位置，在该区域内从感兴趣区域外部执行图像引导的介入程序，并产生指示检测位置的信号 。 成像扫描器包括控制器（114），其基于移动信号激活成像扫描器以扫描感兴趣区域和其中的介入仪器用于一个或多个数据采集周期。

公开(公告)号：US09299169B2

公开(公告)日：2016-03-29

申请号：US13990450

申请日：2011-11-25

申请人： Bernhard Johannes Brendel ,  Thomas Koehler ,  Holger Schmitt ,  Rolf Dieter Bippus ,  Roland Proksa

发明人： Bernhard Johannes Brendel ,  Thomas Koehler ,  Holger Schmitt ,  Rolf Dieter Bippus ,  Roland Proksa

IPC分类号： G06T11/00

CPC分类号： G06T11/003 ,  G06T11/006 ,  G06T2211/424

摘要： A method includes reconstructing measured projection data using an iterative statistical reconstruction algorithm that reduces image artifact caused by differences in variances in projections of the measured projection data used to update a voxel of the image for one or more voxels of the image. A reconstructor includes a processor that reconstructs measured projection data using an iterative statistical reconstruction algorithm that reduces or mitigates image artifact caused by differences in variances in projections used to update a voxel of the image for one or more voxels of the image. A computer readable storage medium encoded with computer executable instructions, which, when executed by a processor of a computer, cause the processor to: reduce image artifact caused by differences in variances in projections used to update a voxel of an image for one or more voxels of the image using an iterative statistical reconstruction algorithm.

摘要翻译： 一种方法包括使用迭代统计重建算法来重建测量的投影数据，所述迭代统计重构算法减少由用于更新图像的一个或多个体素的图像的体素的测量投影数据的投影方差的差异引起的图像伪像。 重构器包括使用迭代统计重建算法来重建测量的投影数据的处理器，其减少或减轻由用于更新图像的一个或多个体素的图像的体素的投影方差的差异引起的图像伪像。 一种用计算机可执行指令编码的计算机可读存储介质，其在由计算机的处理器执行时使处理器能够：减少由用于更新一个或多个体素的图像的体素的投影差异的差异引起的图像伪像 的图像使用迭代统计重建算法。

公开(公告)号：US09047702B2

公开(公告)日：2015-06-02

申请号：US13977042

申请日：2012-01-04

申请人： Holger Schmitt ,  Michael Grass

发明人： Holger Schmitt ,  Michael Grass

IPC分类号： G06K9/00 ,  G06T11/00 ,  A61B6/03 ,  A61B6/00

CPC分类号： G06T11/008 ,  A61B6/032 ,  A61B6/469 ,  A61B6/481 ,  A61B6/488 ,  A61B6/504

摘要： The present invention relates to a computed tomography system (10) and a corresponding method which enable tracking of a contrast material bolus and which involve a reduced radiation dose. The proposed computed tomography system (10) comprises an acquisition unit including an X-ray source (18) and an X-ray detector (30) for acquiring projection data sets (42, 44, 46), a reconstruction unit (41) for reconstructing a planning image (48) from a first projection data set (42), an identification unit (52) for identifying a region of interest (40) in the planning image (48), a selection unit (54) for selecting a projection angle (60) through the region of interest (40), a calculator (62) for calculating a target projection value (64) for a projection of said region of interest (40) with the selected projection angle (60), a control unit (32) for controlling said acquisition unit to acquire a second, reduced projection data set (44) including projection data from projections of said region of interest (40) with the selected projection angle (60), and a comparator (68) for comparing projection values of the second projection data set (44) with the target projection value (64), wherein the control unit (32) is adapted to control the acquisition unit to initiate the acquisition of a third projection data set (46) based on the comparison result (70) and to reconstruct a diagnostic image (50) from the third projection data set (46).

摘要翻译： 本发明涉及计算机断层摄影系统（10）和相应的方法，其能够跟踪造影剂推注并涉及降低的辐射剂量。 所提出的计算机断层摄影系统（10）包括：采集单元，包括用于获取投影数据组（42,44,46）的X射线源（18）和X射线检测器（30）;重建单元（41），用于 从第一投影数据集（42）重建规划图像（48）;识别单元（52），用于识别所述规划图像（48）中的感兴趣区域（40）;选择单元（54），用于选择投影 通过感兴趣区域（40）的角度（60）;计算器（62），用于计算用于所选择的投影角度（60）的所述感兴趣区域（40）的投影的目标投影值（64）;控制单元 （32），用于控制所述获取单元以选择的投影角度（60）获取包括来自所述感兴趣区域（40）的投影的投影数据的第二缩小投影数据集（44），以及比较器 第二投影数据集（44）的投影值与目标投影值（64），w 这里，控制单元（32）适于控制采集单元基于比较结果（70）开始获取第三投影数据集（46），并且从第三投影数据集重建诊断图像（50） （46）。

公开(公告)号：US09044187B2

公开(公告)日：2015-06-02

申请号：US13992302

申请日：2011-12-02

申请人： Thomas Koehler ,  Holger Schmitt ,  Roland Proksa

发明人： Thomas Koehler ,  Holger Schmitt ,  Roland Proksa

IPC分类号： A61B6/00 ,  A61B6/03 ,  G21K1/10 ,  A61B6/06

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4241 ,  A61B6/4291 ,  A61B6/488 ,  A61B6/544 ,  G21K1/10

摘要： An imaging system includes a radiation source (310) configured to rotate around an examination region about a z-axis and having a focal spot that emits a radiation beam that traverses the examination region. The system further includes a radiation sensitive detector array (314) with a plurality of detector pixels that detects radiation traversing the examination region and generates projection data indicative of the detected radiation. The system further includes a dynamic post-patient filter (316) including one or more filter segments (402, 802, 902, 1004, 1102). The filter is configured to selectively and dynamically move in front of the detector array between the detector array and the examination region and into and out of a path of the radiation beam illuminating the detector pixels during scanning an object or subject based on a shape of the object or subject, thereby filtering unattenuated radiation and radiation traversing a periphery of the object or subject.

摘要翻译： 成像系统包括被配置为围绕z轴围绕检查区域旋转并具有发射穿过检查区域的辐射束的焦点的辐射源（310）。 该系统还包括具有多个检测器像素的辐射敏感检测器阵列（314），其检测穿过检查区域的辐射，并产生指示检测到的辐射的投影数据。 该系统还包括动态的患者后过滤器（316），其包括一个或多个过滤器段（402,802,902,1004,1102）。 滤波器被配置为在检测器阵列和检查区域之间选择性地和动态地在检测器阵列之前移动，并且在扫描对象或被摄体期间，在扫描对象或被摄体期间进入和离开照射检测器像素的辐射束的路径， 物体或物体，从而过滤未被衰减的辐射和穿过物体或物体的周边的辐射。

公开(公告)号：US09002090B2

公开(公告)日：2015-04-07

申请号：US13988349

申请日：2011-11-16

申请人： Thomas Koehler ,  Bernhard Johannes Brendel ,  Holger Schmitt ,  Rolf Dieter Bippus

发明人： Thomas Koehler ,  Bernhard Johannes Brendel ,  Holger Schmitt ,  Rolf Dieter Bippus

IPC分类号： G06K9/00 ,  G06T11/00

CPC分类号： G06T11/005 ,  G06T11/008 ,  G06T2211/424

摘要： The invention relates to a forward projection apparatus for performing a forward projection through an image (22), wherein at least one of a number of rays (20, 21) for performing the forward projection, a ray spacing between the rays and a kernel width of an interpolation kernel for calculating interpolated values located on the rays is varied depending on the ray width relative to an effective image element spacing between image elements (24) of the image. This allows reducing artifacts in simulated projection data and, thus, in an image, which is iteratively reconstructed by using the simulated projection data. For example, if the number of provided rays and/or the ray spacing between the provided rays is varied, aliasing artifacts can be reduced. Moreover, if the ray spacing between the provided rays and/or the kernel width of the interpolation kernel is varied, artifacts caused by varying effective kernel widths may be reduced.

摘要翻译： 本发明涉及一种用于通过图像（22）进行向前投影的前投影装置，其中，用于执行向前投影的多个光线（20,21）中的至少一个，光线之间的光线间隔和核宽度 用于计算位于光线上的内插值的插值内核根据相对于图像的图像元素（24）之间的有效图像元素间隔的光线宽度而变化。 这允许减少模拟投影数据中的伪影，并因此减少通过使用模拟投影数据迭代重建的图像。 例如，如果提供的光线的数量和/或所提供的光线之间的光线间隔变化，则可以减少混叠伪影。 此外，如果所提供的光线之间的光线间距和/或内插核的内核宽度发生变化，则可能会降低由变化的有效内核宽度引起的伪影。