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55 条记录 (耗时 0.022 秒)

    Method and apparatus for acquiring a synchronization signal
    31.
    发明授权
    Method and apparatus for acquiring a synchronization signal 有权

    公开(公告)号：US07042854B2

    公开(公告)日：2006-05-09

    申请号：US09768726

    申请日：2001-01-24

    申请人： Bassel Beidas ,  Olga Ritterbush ,  Stanley Kay ,  Yezdi Antia ,  Bala Subramaniam

    发明人： Bassel Beidas ,  Olga Ritterbush ,  Stanley Kay ,  Yezdi Antia ,  Bala Subramaniam

    IPC分类号： H04B7/212

    CPC分类号： H04J3/0611 ,  H04B7/2125 ,  H04L7/0004

    摘要： A method and system for acquiring a time division multiplexed synchronization signal in a satellite communication system is provided. The signal is provided as a series of frames with beacon signals time division multiplexed into at least one time slot of each frame. The beacon signal in each frame comprises a unique word sequence, which is the same in each frame, and a portion of a PN sequence. The entire PN sequence is distributed into a plurality of frames forming a superframe. Initially, the power level of the incoming signal is determined by locating the maximum power received in half time slot intervals. Next a series of frames are correlated against the expected unique word, each at one of a plurality of possible frequencies. The frequency generating the maximum correlation with the unique word is selected. The frequency is fine tuned by comparing the actual arrival time of the unique word in each frame with the estimated arrival time based on the current frequency, and adjusting the frequency accordingly. Also, the start of the superframe is located by correlating the PN sequence portion of each beacon signal against a known PN sequence until a match is found. Once the frequency offset is reduced below a threshold value, and the start of the PN sequence of the incoming signal is located, acquisition is completed.

    Precipitation of proteins from organic solutions
    32.
    发明授权
    Precipitation of proteins from organic solutions 失效
    从有机溶液中沉淀蛋白质

    公开(公告)号：US06562952B1

    公开(公告)日：2003-05-13

    申请号：US09703221

    申请日：2000-10-31

    申请人： Roger A. Rajewski ,  Bala Subramaniam ,  William K. Snavely ,  Fenghui Niu

    发明人： Roger A. Rajewski ,  Bala Subramaniam ,  William K. Snavely ,  Fenghui Niu

    IPC分类号： A23J100

    CPC分类号： A61K9/1688

    摘要： A process for forming small micron-sized (1-10 &mgr;m) protein particles is provided wherein a protein, a solvent system for the protein and an antisolvent for the protein solvent system are contacted under conditions to at least partially dissolve the protein solvent system in the antisolvent, thereby causing precipitation of the protein. The solvent system is made up of at least in part of a halogenated organic alcohol, most preferably 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP). Preferably, a solution of the protein in the solvent system is sprayed through a nozzle into a precipitation zone containing the antisolvent (preferably CO2) under near- or supercritical conditions.

    摘要翻译： 提供了形成小微米尺寸（1-10μm）蛋白质颗粒的方法，其中蛋白质，用于蛋白质的溶剂体系和蛋白质溶剂体系的抗溶剂在至少部分溶解蛋白质溶剂体系的条件下接触 抗溶剂，从而引起蛋白质的沉淀。 溶剂系统由至少部分卤代有机醇，最优选1,1,1,3,3,3-六氟-2-丙醇（HFIP）组成。 优选地，在近或超临界条件下，将蛋白质在溶剂系统中的溶液通过喷嘴喷射到含有抗溶剂（优选CO 2）的沉淀区中。

    Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
    33.
    发明授权
    Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent 失效
    通过从喷射到压缩抗溶剂中的有机溶液重结晶进行颗粒微粉化和纳米化的方法

    公开(公告)号：US5874029A

    公开(公告)日：1999-02-23

    申请号：US723463

    申请日：1996-10-09

    申请人： Bala Subramaniam ,  Said Saim ,  Roger A. Rajewski ,  Valentino Stella

    发明人： Bala Subramaniam ,  Said Saim ,  Roger A. Rajewski ,  Valentino Stella

    IPC分类号： A61K9/16 ,  A61K9/50 ,  B01J2/04 ,  B05D1/02 ,  B29B9/00

    CPC分类号： B05D1/025 ,  A61K9/1676 ,  A61K9/1688 ,  B01J2/04 ,  A61K9/1694 ,  A61K9/5089 ,  B05D2401/90 ,  Y10S977/773

    摘要： A method and an apparatus useful for the production of microparticles and nanoparticles are disclosed in which a compressed fluid and a solution including a solvent and a solute are introduced into a nozzle to produce a mixture. The mixture is then passed out of the nozzle to produce a spray of atomized droplets. The atomized droplets are contacted with a supercritical antisolvent to cause depletion of the solvent in the droplets so that particles are produced from the solute. Preferably, these particles have an average diameter of 0.6 .mu.m or less. The invention can be used in the pharmaceutical, food, chemical, electronics, catalyst, polymer, pesticide, explosives, and coating industries, all of which have a need for small-diameter particles.

    摘要翻译： 公开了一种用于生产微粒和纳米颗粒的方法和装置，其中将压缩流体和包含溶剂和溶质的溶液引入喷嘴中以产生混合物。 然后将混合物从喷嘴中排出以产生雾化液滴的喷雾。 雾化的液滴与超临界反溶剂接触以引起液滴中溶剂的消耗，使得从溶质中产生颗粒。 优选地，这些颗粒的平均直径为0.6μm以下。 本发明可用于制药，食品，化工，电子，催化剂，聚合物，农药，爆炸物和涂料工业，所有这些都需要小直径颗粒。

    Spray Process for Selective Oxidation
    36.
    发明申请
    Spray Process for Selective Oxidation 有权
    选择氧化喷涂工艺

    公开(公告)号：US20120022287A1

    公开(公告)日：2012-01-26

    申请号：US13258159

    申请日：2010-03-23

    申请人： Bala Subramaniam ,  Daryle H. Busch ,  Fenghul Niu

    发明人： Bala Subramaniam ,  Daryle H. Busch ,  Fenghul Niu

    IPC分类号： C07C51/265

    CPC分类号： C07C51/255 ,  B01J4/002 ,  B01J10/007 ,  B01J2219/00006 ,  B01J2219/00063 ,  B01J2219/00065 ,  B01J2219/00162 ,  C07C51/265 ,  C07C63/00

    摘要： Oxidation process can include: introducing small droplets of liquid reaction mixture having oxidizable reactant, catalyst, and solvent into a reaction zone containing oxygen and diluent gas; and oxidizing the reactant with the oxygen at a suitable reaction temperature and a suitable reaction pressure to produce an oxidized product. The liquid reaction mixture can have an aromatic feedstock having an oxidizable substituent as the oxidizable reactant. The oxidized product can include an aromatic compound having at least one carboxylic acid. For example, the aromatic feedstock can include a benzene ring having at least one oxidizable alkyl substituent, furan hetero-ring having at least one oxidizable alkyl substituent, a naphthalene poly-ring having at least one oxidizable alkyl substituent, derivatives thereof, and mixtures thereof.

    摘要翻译： 氧化过程可以包括：将具有可氧化反应物，催化剂和溶剂的小液滴的液体反应混合物引入含有氧气和稀释气体的反应区; 并在合适的反应温度和合适的反应压力下用氧氧化反应物以产生氧化产物。 液体反应混合物可具有具有可氧化取代基的芳族原料作为可氧化反应物。 氧化产物可以包括具有至少一个羧酸的芳族化合物。 例如，芳族原料可以包括具有至少一个可氧化烷基取代基的苯环，具有至少一个可氧化烷基取代基的呋喃异环，具有至少一个可氧化烷基取代基的萘多环，其衍生物及其混合物 。

    METHOD FOR PRECIPITATION OF SMALL MEDICAMENT PARTICLES INTO USE CONTAINERS
    39.
    发明申请
    METHOD FOR PRECIPITATION OF SMALL MEDICAMENT PARTICLES INTO USE CONTAINERS 有权
    将小剂量颗粒降解成使用容​​器的方法

    公开(公告)号：US20080089944A1

    公开(公告)日：2008-04-17

    申请号：US11870554

    申请日：2007-10-11

    申请人： Roger A. Rajewski ,  Bala Subramaniam ,  Fenghui Niu

    发明人： Roger A. Rajewski ,  Bala Subramaniam ,  Fenghui Niu

    IPC分类号： A61K9/14

    CPC分类号： A61K9/1688 ,  B01J2/02 ,  B01J2/04 ,  B01J2/18

    摘要： Commercially feasible methods for lyophobic precipitation of liquid-dispersed or dissolved material (e.g., medicaments) are provided wherein a plurality of individual, open containers (22) each containing a quantity (84) of a solution or dispersion are treated within a common pressurizable chamber (12). In this process, desired near-supercritical or supercritical temperature and pressure conditions are established for a selected antisolvent gas such as carbon dioxide, and an ultrasonic device (14) is actuated to generate high energy ultrasonic waves in the chamber (12). This leads to intense mixing of the antisolvent with the liquid solution or dispersion within the containers (22), with consequent solvent removal and material precipitation.

    摘要翻译： 提供了用于液体分散或溶解的材料（例如药物）的疏液沉淀的商业上可行的方法，其中每个含有（84）溶液或分散体的多个单独的开放容器（22）在共同的可加压室 （12）。 在这个过程中，为所选择的反溶剂气体例如二氧化碳建立了所需的近临界或超临界温度和压力条件，并且致动超声波装置（14）以在腔室（12）中产生高能超声波。 这导致抗溶剂与容器（22）内的液体溶液或分散体的强烈混合，随后进行溶剂去除和材料沉淀。