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公开(公告)号：US08403980B2
公开(公告)日：2013-03-26
申请号：US12717425
申请日：2010-03-04
IPC分类号： A61F2/82
CPC分类号： C22C27/02 , A61L27/047 , A61L31/022 , A61L31/18 , C22C27/00 , C22C30/00
摘要： The present invention relates to a medical device or implant made at least in part of a high strength, low modulus metal alloy comprising Niobium, Tantalum, and at least one element selected from the group consisting of Zirconium, Tungsten, and Molybdenum. The medical devices according to the present invention provide superior characteristics with regard to bio-compatibility, radio-opacity and MRI compatibility.
摘要翻译： 本发明涉及至少部分由包含铌，钽以及选自锆，钨和钼的至少一种元素的高强度低模量金属合金制成的医疗器械或植入物。 根据本发明的医疗装置在生物相容性，无线电透明性和MRI兼容性方面提供优异的特性。
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公开(公告)号：US08292913B2
公开(公告)日：2012-10-23
申请号：US13152081
申请日：2011-06-02
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译： 根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。 一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。 然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。 气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。 材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。 此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。 袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。
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公开(公告)号：US08246670B2
公开(公告)日：2012-08-21
申请号：US11844313
申请日：2007-08-23
申请人： Randolf Von Oepen , Thomas Michael Rieth , Lorcan James Coffey , Richard Roy Newhauser , Travis Richard Yribarren
发明人： Randolf Von Oepen , Thomas Michael Rieth , Lorcan James Coffey , Richard Roy Newhauser , Travis Richard Yribarren
IPC分类号： A61F2/06
CPC分类号： A61M25/1011 , A61F2/86 , A61F2/954 , A61F2/958 , A61F2002/065 , A61M25/0071 , A61M2025/018 , A61M2025/1045 , A61M2025/1081 , A61M2025/1093
摘要： A system for delivering a medical device, such as an angioplasty balloon, includes two catheter shafts. The distal portion of a first shaft includes a first balloon and is narrower than the proximal portion. A second catheter shaft includes a second balloon and is connected to a medial portion of the first shaft. The second shaft includes a guidewire passageway which is in communication with the passageway of a third shaft that is removably connected to the first shaft. The distal tips of the first and second balloons are connected together to allow the system to be advanced to an anatomical site using a single guidewire. A second guidewire may be used to separate the distal ends of the balloons and to position the balloons at vascular bifurcation. A stent can be crimped onto the balloons such that inflation of the balloons implants the stent within the bifurcation.
摘要翻译： 用于递送诸如血管成形术气囊的医疗装置的系统包括两个导管轴。 第一轴的远侧部分包括第一球囊并且比近侧部分窄。 第二导管轴包括第二球囊并连接到第一轴的中间部分。 第二轴包括导丝通道，其与第三轴的通道连通，该第三轴可移除地连接到第一轴。 第一和第二气囊的远侧末端连接在一起，以允许系统使用单个导丝进入解剖部位。 可以使用第二导丝来分离气囊的远端并将气囊定位在血管分叉处。 支架可以卷曲到气囊上，使得气囊的充气将支架植入分叉内。
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34.发明申请公开(公告)号：US20120027872A1
公开(公告)日：2012-02-02
申请号：US13174049
申请日：2011-06-30
申请人： Stevan Nielsen , Bodo Quint , Randolf Von Oepen , Kenneth J. Michlitsch , Gerd Seibold , Tommy Conzelmann , Ib Erling Joergensen
发明人： Stevan Nielsen , Bodo Quint , Randolf Von Oepen , Kenneth J. Michlitsch , Gerd Seibold , Tommy Conzelmann , Ib Erling Joergensen
CPC分类号： A61B17/00491 , A61B17/0057 , A61B2017/00654 , A61B2017/0472
摘要： Apparatus is provided for sealing a vascular puncture by causing a reduction in the circumference of the puncture tract through delivery of a closure agent into tissue surrounding the puncture tract. A resultant inflammatory response and volumetric increase cause the tissue to swell into the puncture tract, thereby sealing it.
摘要翻译： 提供了用于通过将封闭剂递送到穿刺道周围的组织中引起穿刺道周围的减少来密封血管穿刺的装置。 产生的炎症反应和体积增加导致组织溶胀到穿刺道中，从而将其密封。
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35.发明授权Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation 有权用于支架置入的方法和装置包括增强的栓塞保护以及改进的针对再狭窄和血栓形成的保护公开(公告)号：US08088157B2
公开(公告)日：2012-01-03
申请号：US11731882
申请日：2007-03-30
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
摘要翻译： 提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。 提供优选的支架设计，以及优选的制造技术。 还提供了用于血管分支的装置和方法。 此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。 预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。
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36.发明授权Catheter having an auxiliary lumen for use with a functional measurement wire 有权导管具有与功能测量线一起使用的辅助流明公开(公告)号：US08075549B2
公开(公告)日：2011-12-13
申请号：US12652650
申请日：2010-01-05
IPC分类号： A61M31/00
CPC分类号： A61M25/0029 , A61M25/10 , A61M2025/0183 , C09J151/06
摘要： The present invention relates to a surgical catheter, and more particularly, a balloon catheter having an auxiliary lumen configured to permit the advancement of a functional measurement wire to a treatment site. The auxiliary lumen communicates with a working lumen that is configured to permit the advancement of a guidewire and the functional measurement wire, so that the guidewire and functional measurement wire may selectively be advanced to the treatment site during a surgical procedure.
摘要翻译： 技术领域本发明涉及一种外科导管，更具体地说，涉及具有配置为允许将功能测量导线推进到治疗部位的辅助腔的球囊导管。 辅助管腔与被配置为允许推进导丝和功能测量线的工作腔连通，使得导引线和功能测量线可以在外科手术期间选择性地前进到治疗部位。
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公开(公告)号：US20110213451A1
公开(公告)日：2011-09-01
申请号：US13037008
申请日：2011-02-28
CPC分类号： A61F2/0095 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665
摘要： Device shields for packaging and protecting medical devices during storage and deployment. A device shield includes a housing configured to maintain a medical device and at least a portion of a medical device delivery apparatus within the housing, and a limit element having a first constraining position and a second open position.
摘要翻译： 在存储和部署期间用于包装和保护医疗设备的设备屏蔽。 设备屏蔽包括被配置为将医疗设备和医疗设备传送设备的至少一部分保持在壳体内的壳体，以及具有第一约束位置和第二打开位置的限制元件。
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38.发明申请APPARATUS FOR DELIVERY AND DEPLOYMENT OF AN EXPANDABLE STENT WITHIN A BLOOD VESSEL 有权用于在血管中输送和释放可膨胀的血栓的装置公开(公告)号：US20110160847A1
公开(公告)日：2011-06-30
申请号：US13012587
申请日：2011-01-24
申请人： Randolf Von Oepen , Volker Trösken , Volker Marx , Armin Stopper , Louise Balfe , Lorcan James Coffey
发明人： Randolf Von Oepen , Volker Trösken , Volker Marx , Armin Stopper , Louise Balfe , Lorcan James Coffey
IPC分类号： A61F2/82
CPC分类号： A61F2/958
摘要： An improved apparatus for delivering and deployment of an expandable stent with a protection sheath within a blood vessel is provided. The system comprises a fluid pressure device which is coupled with a retraction device for the protection sheath such that after retraction of the protection sheath the stent is automatically deployed by the fluid pressure device. The advantage of the invention is an easy and simple operation of the apparatus.
摘要翻译： 提供了一种用于在血管内输送和展开具有保护护套的可扩张支架的改进装置。 该系统包括流体压力装置，该流体压力装置与用于保护护套的收回装置相耦合，使得在保护护套收回之后，支架由流体压力装置自动展开。 本发明的优点是装置的简单和简单的操作。
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公开(公告)号：US07942854B1
公开(公告)日：2011-05-17
申请号：US12022047
申请日：2008-01-29
申请人： Randolf Von Oepen , Greg Chan
发明人： Randolf Von Oepen , Greg Chan
IPC分类号： A61M5/178
CPC分类号： A61M39/0208 , A61B17/3478 , A61B2017/00243 , A61B2017/00247 , A61B2017/00349 , A61B2018/00392 , A61M25/0084 , A61M25/0136 , A61M25/0147 , A61M25/04 , A61M25/0662 , A61M39/0247 , A61M2025/0092 , A61M2025/0681 , A61M2039/0223 , A61M2039/0261
摘要： An agent delivery catheter that uses an anchoring needle and injection needle for treating tissue, such as infarcted heart tissue, includes a first needle, a second needle extendable through the first needle and a control unit for displacing and adjusting the position of both the first and second needles relative to a distal end of the delivery catheter.
摘要翻译： 使用锚定针和注射针来治疗组织的药剂递送导管，例如梗死心脏组织，包括第一针，可穿过第一针的第二针和用于移位和调节第一和第二针的位置的控制单元 第二针相对于输送导管的远端。
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公开(公告)号：US07887577B2
公开(公告)日：2011-02-15
申请号：US10903080
申请日：2004-07-30
申请人： Randolf Von Oepen , Gerd Seibold
发明人： Randolf Von Oepen , Gerd Seibold
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558
摘要： The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected by connection elements. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.
摘要翻译： 本发明提供了一种支架，其包括管状柔性体，其具有壁，所述壁具有可从收缩输送构型扩展到展开构造的腹板结构。 网状结构包括多个相邻的网状图案，其中每个网状图案由邻接的网构成，并且网状图案通过连接元件互连。 每个邻接的腹板包括插入在两个横向部分之间以形成凹形或凸形构造的中心部分。
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