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    Automated extraction and purification of samples using optical tweezers
    36.
    发明授权
    Automated extraction and purification of samples using optical tweezers 失效
    使用光学镊子自动提取和纯化样品

    公开(公告)号：US07875845B2

    公开(公告)日：2011-01-25

    申请号：US11298565

    申请日：2005-12-12

    申请人： Joseph S. Plewa ,  Evan B. Tanner ,  Daniel M. Mueth ,  Crystal J. Duke ,  Kevin J. Ehrenreich

    发明人： Joseph S. Plewa ,  Evan B. Tanner ,  Daniel M. Mueth ,  Crystal J. Duke ,  Kevin J. Ehrenreich

    IPC分类号： H01S1/00 ,  C12Q1/00 ,  G01N1/18 ,  G01N21/00

    CPC分类号： G02B21/32 ,  B01L3/502761 ,  G01N1/34 ,  G01N15/1463 ,  G01N2001/007 ,  G01N2015/1454 ,  G01N2015/149 ,  G02B5/32 ,  Y10T436/25375

    摘要： An apparatus and method for purifying a forensic sample using an automated extraction and purification system includes optical tweezers; an input channel through which the sample is introduced; a chamber which receives the sample from the input channel; a collection channel through which selected particles of the sample are removed; and an output through which unselected particles of the sample are removed. At least one buffer input channel is provided. The input channel may allow sedimentation of the sample into the chamber by gravity. In another arrangement, the system includes an optical trapping system; a first channel through which the sample is introduced; a second channel through which buffer is introduced; wherein the optical tweezers are used to move selected particles of the sample from the first channel to the second channel. The selected particles may be sperm. The optical tweezers preferably utilize holographic optical trapping.

    摘要翻译： 使用自动提取和净化系统来净化法医样品的装置和方法包括光学镊子; 导入样品的输入通道; 从输入通道接收样品的室; 取出样品的所选粒子的收集通道; 以及去除样品的未选择的颗粒的输出。 提供至少一个缓冲器输入通道。 输入通道可以允许样品通过重力沉降到室中。 在另一种布置中，该系统包括光学捕获系统; 引入样品的第一通道; 引入缓冲液的第二通道; 其中所述光学镊子用于将所述样品的选定颗粒从所述第一通道移动到所述第二通道。 所选择的颗粒可能是精子。 光学镊子优选利用全息光学捕获。

    Reperfusion balloon inflation device
    38.
    发明授权
    Reperfusion balloon inflation device 有权
    再灌注气球充气装置

    公开(公告)号：US08366659B2

    公开(公告)日：2013-02-05

    申请号：US13032743

    申请日：2011-02-23

    申请人： Kevin J. Ehrenreich ,  Jesus Magana

    发明人： Kevin J. Ehrenreich ,  Jesus Magana

    IPC分类号： A61M29/00

    CPC分类号： A61M25/1002 ,  A61M25/10186 ,  A61M25/10187 ,  A61M39/105 ,  A61M39/22 ,  A61M2025/004 ,  A61M2025/0059

    摘要： An ischemic postconditioning system and related method comprising a catheter including a plurality of lumens and at least one expandable member with at least one chamber including a moveable plunger and a return mechanism operatively engaged with the plunger. The moveable plunger divides the at least one chamber into first and second volumes. A first pressure source is provided having a first fluid at a first pressure and is disposed in fluid communication with the first volume of the chamber. Further, a second pressure source is provided having a second fluid at a second pressure and is disposed in fluid communication with the second volume of the chamber. Similarly, the at least one expandable member is disposed in fluid communication with the second volume of the chamber. The first fluid supplied by the first pressure source displaces the plunger in a first direction delivering at least a portion of the second fluid into the at least one expandable member. Also, the return mechanism displaces the plunger in a second direction delivering the second fluid from the second pressure source to the second volume of the chamber.

    摘要翻译： 缺血后处理系统和相关方法包括包括多个管腔的导管和至少一个具有至少一个腔室的可扩张构件，所述至少一个腔室包括可移动柱塞和与柱塞可操作地接合的返回机构。 可移动柱塞将至少一个室分成第一和第二体积。 提供第一压力源，其具有在第一压力下的第一流体并且与腔室的第一体积流体连通地设置。 此外，提供第二压力源，其具有在第二压力下的第二流体并且设置成与腔室的第二体积流体连通。 类似地，至少一个可膨胀构件设置成与腔室的第二体积流体连通。 由第一压力源供应的第一流体沿第一方向移动柱塞，将第二流体的至少一部分输送到至少一个可扩张构件中。 此外，返回机构使第二流体从第二压力源向腔室的第二体积传递的第二方向移位柱塞。