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公开(公告)号：US08512727B2
公开(公告)日：2013-08-20
申请号：US10784900
申请日：2004-02-24
申请人： Eugene R. Cooper , Tuula Ryde , John Pruitt , Laura Kline
发明人： Eugene R. Cooper , Tuula Ryde , John Pruitt , Laura Kline
CPC分类号： A61K9/145 , A61K9/0019 , A61K9/0056 , A61K9/0095 , A61K9/146 , A61K9/2059 , Y10T428/2982 , Y10T428/2985 , Y10T428/2987
摘要： The present invention is directed to nanoparticulate compositions comprising meloxicam. The meloxicam particles of the composition have an effective average particle size of less than about 2000 nm.
摘要翻译： 本发明涉及包含美洛昔康的纳米颗粒组合物。 组合物的美洛昔康颗粒具有小于约2000nm的有效平均粒度。
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公开(公告)号：US20100266705A1
公开(公告)日：2010-10-21
申请号：US12826557
申请日：2010-06-29
申请人： Douglas Hovey , John Pruitt , Tuula Ryde
发明人： Douglas Hovey , John Pruitt , Tuula Ryde
CPC分类号： A61K9/14 , A61K9/0095 , A61K9/08 , A61K9/10 , A61K9/145 , A61K9/146 , A61K9/5123 , A61K9/5138 , A61K9/5161 , A61K9/5169 , A61K31/57 , A61K31/573 , A61K45/06 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/42 , A61K2300/00
摘要： The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
摘要翻译： 本发明涉及包含甲孕酮的纳米颗粒组合物。 组合物的甲孕酮颗粒具有小于约2000nm的有效平均粒度。
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33.发明申请公开(公告)号：US20080213378A1
公开(公告)日：2008-09-04
申请号：US11980586
申请日：2007-10-31
申请人： Eugene R. Cooper , Douglas Hovey , Greta Cary , Marie Lindner , Elaine Liversidge , Gary G. Liversidge , Tuula Ryde
发明人： Eugene R. Cooper , Douglas Hovey , Greta Cary , Marie Lindner , Elaine Liversidge , Gary G. Liversidge , Tuula Ryde
IPC分类号： A61K9/14 , A61K31/366 , A61P3/06
CPC分类号： A61K9/145 , A61K9/146 , A61K31/045 , A61K31/185 , A61K31/216 , A61K31/366 , A61K31/40 , A61K31/4025 , A61K31/405 , A61K31/4164 , A61K31/44 , A61K45/06
摘要： The present invention is directed to nanoparticulate compositions comprising statin such as lovastatin or simvastatin. The statin particles of the composition have an effective average particle size of less than about 2000 nm. In another aspect of this invention, novel combinations of statins and other cholesterol lowering agents are described and methods of using same are taught.
摘要翻译： 本发明涉及包含他汀类药物如洛伐他汀或辛伐他汀的纳米颗粒组合物。 组合物的他汀类颗粒具有小于约2000nm的有效平均粒度。 在本发明的另一方面，描述了他汀类和其它降胆固醇剂的新组合，并教导了其使用方法。
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公开(公告)号：US20080107741A1
公开(公告)日：2008-05-08
申请号：US11928278
申请日：2007-10-30
申请人： Elaine Merisko-Liversidge , H. Bosch , Greta Cary , John Pruitt , Tuula Ryde , Rajeev Jain , Amy Walters
发明人： Elaine Merisko-Liversidge , H. Bosch , Greta Cary , John Pruitt , Tuula Ryde , Rajeev Jain , Amy Walters
CPC分类号： A61K31/00 , A61K9/145 , A61K9/146 , A61K9/148 , A61K31/565
摘要： Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.
摘要翻译： 描述包含至少一种难溶性血管发生抑制剂和至少一种表面稳定剂的纳米颗粒组合物。 纳米颗粒组合物具有小于约2000nm的平均粒度。 本发明还描述了制备和使用这些组合物的方法。
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公开(公告)号：US07101576B2
公开(公告)日：2006-09-05
申请号：US10412669
申请日：2003-04-14
申请人： Douglas Hovey , John Pruitt , Tuula Ryde
发明人： Douglas Hovey , John Pruitt , Tuula Ryde
CPC分类号： A61K9/0095 , A61K9/145 , A61K9/146 , A61K31/57 , A61K45/06 , A61K47/20 , A61K47/32 , A61K47/38 , A61K2300/00
摘要： The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
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