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公开(公告)号：US20070293922A1
公开(公告)日：2007-12-20
申请号：US11424349
申请日：2006-06-15
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： Medical electrical leads are provided including fixation features for acute and chronic fixation of a portion of the respective leads within the cardiac venous system. The medical electrical lead includes an elongate body having proximal and distal regions. Tissue contacting portions are selectively located in the distal region to contact an inner surface of the cardiac vessel when the lead is in an implanted position. The tissue contacting portion(s) include fixation features adapted to frictionally engage the inner surface of the cardiac vessel and promote tissue in-growth for chronic fixation. In some embodiments, the fixation features are detachable from the lead such that the lead can be extracted from its implanted position after tissue in-growth occurs.
摘要翻译： 提供了医疗电引线，其包括用于心脏静脉系统内的各个引线的一部分的急性和慢性固定的固定特征。 医疗电线包括具有近端和远端区域的细长体。 当引线处于植入位置时，组织接触部分选择性地位于远端区域中以接触心脏血管的内表面。 组织接触部分包括适于摩擦地接合心脏血管的内表面并促进用于慢性固定的组织生长的固定特征。 在一些实施例中，固定特征可从铅脱离，使得在组织生长发生之后，引线可以从其植入位置提取。
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公开(公告)号：US20070282412A1
公开(公告)日：2007-12-06
申请号：US11421990
申请日：2006-06-02
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , A61B18/1492 , A61N1/056 , A61N2001/0585
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译： 适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。 腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。 在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。 在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。
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公开(公告)号：US07174222B2
公开(公告)日：2007-02-06
申请号：US10675932
申请日：2003-09-30
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A system and method facilitates inserting a cardiac lead into a patient's vasculature. The cardiac lead system includes a cardiac lead having a lumen, and a guide member displaceable within the lumen. The guide member includes a guide wire extension that extends distal to the elongated body of the guide member. The guide wire extension is dimensioned to pass through an external distal opening of the cardiac lead lumen. Engagement of stop features or a stop mechanism of the cardiac lead system provides a push point for advancing the cardiac lead system through the patient's anatomy.
摘要翻译： 系统和方法有助于将心脏铅插入患者的脉管系统中。 心脏引导系统包括具有内腔的心脏引线和可在内腔内移位的引导部件。 引导构件包括在引导构件的细长主体的远侧延伸的导丝延伸部。 引导线延伸部的尺寸设计成穿过心脏引流管腔的外部远端开口。 心脏引导系统的停止特征或停止机制的接合为心脏引导系统通过患者的解剖结构提供了推动点。
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公开(公告)号：US07089065B2
公开(公告)日：2006-08-08
申请号：US10730269
申请日：2003-12-09
申请人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
发明人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A finishing wire having temporary locking means to lock the finishing wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
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公开(公告)号：US06129750A
公开(公告)日：2000-10-10
申请号：US274620
申请日：1999-03-23
申请人： Bruce A. Tockman , Randy W. Westlund , Stuart R. Chastain , Brian D. Soltis , Dwight A. Skinner
发明人： Bruce A. Tockman , Randy W. Westlund , Stuart R. Chastain , Brian D. Soltis , Dwight A. Skinner
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： An apparatus for fixing a cardiac lead in place within the vasculature of the heart includes a coil having a normal helical shape and a stylet for holding the coil straight during insertion of the coil through a lumen of the lead. Upon retraction of the stylet, the coil returns to its helical shape along with the lead, forcing portions of the lead into contact with the vessel wall.
摘要翻译： 用于将心脏引线固定在心脏脉管内的设备包括具有正常螺旋形状的线圈和用于在线圈插入线圈的内腔期间将线圈保持直线的探针。 当探针回缩时，线圈与引线一起返回其螺旋形状，迫使引线的部分与血管壁接触。
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公开(公告)号：US5925073A
公开(公告)日：1999-07-20
申请号：US27821
申请日：1998-02-23
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： An intravenous lead for use with a cardiac device for implantation in the coronary venous system of the heart includes a lead body that is adapted to be routed through the vascular system into the coronary sinus with the distal end portion of the lead placed in the great cardiac vein or branch vein. The lead body includes a preformed section disposed just proximal of its tip so that the lead body exhibits a two-dimensional wave having peaks and valleys for contacting the endothelial layer of the vein at discrete, longitudinally spaced points to stabilize the electrode against displacement.
摘要翻译： 用于心脏装置用于植入心脏冠状静脉系统的静脉导管包括引线体，其适于通过血管系统引导到冠状窦中，将引线的远端部分放置在大心脏中 静脉或分支静脉。 引线体包括设置在其尖端附近的预成型部分，使得引线体呈现出具有峰和谷的二维波，用于在离散的纵向间隔的点处接触静脉的内皮层，以使电极抵抗位移。
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37.发明授权公开(公告)号：US08694129B2
公开(公告)日：2014-04-08
申请号：US12686050
申请日：2010-01-12
申请人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
发明人： Dan Li , Allan C. Shuros , Andrea Acuna , Bruce A. Tockman
IPC分类号： A61B5/02
CPC分类号： A61N1/056 , A61B5/042 , A61B5/6846 , A61B5/6852 , A61M25/0082 , A61M25/01 , A61M25/0102 , A61M25/0662 , A61M2025/0681 , A61N1/37211 , A61N2001/0585
摘要： Systems and methods for deploying a sensor assembly onto a cardiac lead are disclosed. The sensor assembly can include a resilient cuff having one or more sensor modules for sensing physiological parameters within the body. The resilient cuff may have a substantially cylindrical shape having an inner diameter that is smaller than an outer diameter of the lead body onto which the cuff is deployed such that the cuff is retained on the lead body by frictional forces. The sensor assembly may be deployed in conjunction with a new lead to be implanted within a chamber of the patient's heart or a body vessel, or may be deployed onto an existing, implanted lead implanted within the patient's body.
摘要翻译： 公开了将传感器组件部署到心脏引线上的系统和方法。 传感器组件可以包括具有用于感测身体内的生理参数的一个或多个传感器模块的弹性袖带。 弹性箍可以具有基本上圆柱形的形状，其内径小于引导体的外径，袖带在其上展开，使得袖带通过摩擦力保持在引线体上。 传感器组件可以与将要植入患者心脏或身体容器的腔室内的新导线一起部署，或者可以部署到植入患者体内的现有植入的导线上。
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公开(公告)号：US08603031B2
公开(公告)日：2013-12-10
申请号：US13540362
申请日：2012-07-02
申请人： Peter Callas , Gary L. Hague , John S. Greenland , Bruce A. Tockman , Peter T. Kelley , Jason A. Shiroff , David B. Yingling , Theodore J. Schulte
发明人： Peter Callas , Gary L. Hague , John S. Greenland , Bruce A. Tockman , Peter T. Kelley , Jason A. Shiroff , David B. Yingling , Theodore J. Schulte
CPC分类号： A61B17/3478 , A61B2017/306 , A61M25/0084
摘要： A device and method for accessing a pericardial space of the heart includes a shaft having a cavity at a distal end, a suction lumen terminating in a distal port within the cavity and a hollow needle having a distal tip extending into the cavity. The cavity may be a recess in the shaft into which the distal tip of the needle fixedly protrudes. In other embodiments, the cavity is formed by an inflatable member positioned at the distal end of the shaft and the needle is slidable relative to the shaft. Suction is applied at the cavity to draw a pericardial bleb. The needle pierces the pericardial bleb for accessing the pericardial space and also facilitates delivery of payloads into the pericardial space.
摘要翻译： 用于访问心脏心包空间的装置和方法包括：具有在远端处的空腔的轴，位于空腔内的远端端口中的抽吸腔，以及具有延伸到空腔中的远端的中空针。 空腔可以是轴中的凹部，其中针的远侧末端固定地突出。 在其他实施例中，空腔由位于轴的远端处的可充气构件形成，并且针可相对于轴滑动。 在空腔处抽取吸入心包泡。 针刺穿心包泡，用于进入心包空间，并且还有助于将载荷递送到心包空间中。
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39.发明申请公开(公告)号：US20130090701A1
公开(公告)日：2013-04-11
申请号：US13690068
申请日：2012-11-30
申请人： Lili Liu , Mohan Krishnan , Bruce A. Tockman , David R. Wulfman
发明人： Lili Liu , Mohan Krishnan , Bruce A. Tockman , David R. Wulfman
IPC分类号： A61N1/365
CPC分类号： A61N1/36564 , A61M25/0041 , A61M2025/0002 , A61M2205/3344 , A61N1/056 , A61N1/3627 , A61N1/36585 , A61N2001/0585
摘要： A cardiac rhythm management system comprises a medical electrical lead, a pressure sensing element, and an implantable pulse generator. The lead is sized to be advanced through the right atrium and coronary sinus into a coronary vein adjacent to the left ventricle. The lead includes an opening intermediate its proximal and distal ends, and a lumen extending longitudinally within the body in communication with the opening. The pressure sensing element is movably disposed in lead lumen and is dimensioned to extend through the opening in the lead, and includes a flexible, elongated conductive member having a distal end, and a pressure transducer coupled to the distal end of the conductive member. The pulse generator is configured to receive cardiac rhythm signals from the electrode and fluid pressure signals from the pressure transducer.
摘要翻译： 心律管理系统包括医疗电引线，压力感测元件和可植入脉冲发生器。 铅的大小可以通过右心房和冠状窦进入与左心室相邻的冠状静脉。 引线包括在其近端和远端之间的开口，以及在主体内与开口连通的纵向延伸的内腔。 压力感测元件可移动地设置在引导腔中，并且其尺寸设计成延伸穿过引线中的开口，并且包括具有远端的柔性细长导电构件和耦合到导电构件的远端的压力传感器。 脉冲发生器被配置为从电极接收心律信号和来自压力传感器的流体压力信号。
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公开(公告)号：US08313478B2
公开(公告)日：2012-11-20
申请号：US12984965
申请日：2011-01-05
IPC分类号： A61M25/01
CPC分类号： A61M25/0041 , A61M25/0105 , A61M25/0136
摘要： A catheter assembly for cannulating an ostium of a coronary sinus of a heart comprises an outer catheter member and an inner catheter member. The outer catheter member has a distal end portion including a deflectable distal end and a lumen extending through the deflectable distal end, wherein the distal end portion includes regions of varying stiffness and has a pre-formed curvature. The inner catheter member is slidably and rotatably disposed within the lumen of the outer catheter member, and has a distal end portion including a distal end, and a lumen extending through the distal end. The distal end portion of the inner catheter member has regions of varying stiffness and a pre-formed curvature. The outer and inner catheter members are configured such that relative translation and rotation of the outer and inner catheter members causes the distal end of the outer catheter member to assume a plurality of two and three dimensional shapes.
摘要翻译： 用于插入心脏冠状窦口的导管组件包括外导管构件和内导管构件。 外导管构件具有包括可偏转远端和延伸穿过可偏转远端的内腔的远端部分，其中远端部分包括具有变化刚度的区域并且具有预先形成的曲率。 内导管构件可滑动地且可旋转地设置在外导管构件的内腔内，并且具有包括远端的远端部分和延伸穿过远端的内腔。 内导管构件的远端部分具有变化的刚度和预先形成的曲率的区域。 外导管构件和内导管构件被构造成使得外导管构件和内导管构件的相对平移和旋转导致外导管构件的远端呈现多个二维和三维形状。
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