公开(公告)号：US20090047706A1

公开(公告)日：2009-02-19

申请号：US11817905

申请日：2006-03-17

申请人： Kuniki Kino ,  Yuji Nakazawa ,  Makoto Yagasaki

发明人： Kuniki Kino ,  Yuji Nakazawa ,  Makoto Yagasaki

IPC分类号： C12P21/02 ,  C07K14/00 ,  C12N9/10 ,  C07H21/04 ,  C12N15/54 ,  C12N1/21

CPC分类号： G02B21/26 ,  C12N9/93 ,  G02B21/362

摘要： The present invention provides: a protein having dipeptide-synthesizing activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant transformed with the recombinant DNA; a process for producing the protein having dipeptide-synthesizing activity using the transformant or the like; a process for producing a dipeptide using the protein having dipeptide-synthesizing activity; and a process for producing a dipeptide using, as an enzyme source, a culture of a transformant or a microorganism which produces the protein having dipeptide-synthesizing activity or the like.

公开(公告)号：US5695972A

公开(公告)日：1997-12-09

申请号：US653042

申请日：1996-05-24

申请人： Yasuichiro Suga ,  Masato Ikeda ,  Kuniki Kino

发明人： Yasuichiro Suga ,  Masato Ikeda ,  Kuniki Kino

IPC分类号： C12N1/20 ,  C12P13/06 ,  C12R1/19 ,  C12N1/00 ,  C12P13/08

CPC分类号： C12N1/20 ,  C12P13/06 ,  Y10S435/849

摘要： The present invention provide a method for the industrial production of L-isoleucine which is useful as pharmaceuticals, foods, feed additives and the like. The method comprises cultivating in a nutrient medium a microorganism belonging to the genus Escherichia which is capable of rapidly growing in a medium containing L-homoserine as the single nitrogen source and has an ability to produce L-isoleucine in the medium, producing and accumulate L-isoleucine in a culture and recovering L-isoleucine therefrom.

摘要翻译： 本发明提供了用作药物，食品，饲料添加剂等的L-异亮氨酸工业化生产的方法。 该方法包括在营养培养基中培养属于埃希氏菌属的微生物，其能够在含有L-高丝氨酸的培养基中作为单一氮源快速生长，并且具有在培养基中产生L-异亮氨酸的能力，产生和积累L - 异亮氨酸，从其中回收L-异亮氨酸。

公开(公告)号：US4725541A

公开(公告)日：1988-02-16

申请号：US583378

申请日：1984-02-24

申请人： Yukinobu Kotani ,  Kuniki Kino

发明人： Yukinobu Kotani ,  Kuniki Kino

IPC分类号： C12P13/24 ,  C12R1/15 ,  C12N1/20

CPC分类号： C12R1/15 ,  C12P13/24 ,  Y10S435/843

摘要： L-histidine is produced by culturing, in a nutrient medium, an L-histidine producing mutant microorganism belonging to the genus Corynebacterium. The mutant is resistant to a precursor for ubiquinone biosynthesis. L-histidine is accumulated in the culture liquor and is recovered therefrom.

摘要翻译： 通过在营养培养基中培养属于棒杆菌属的L-组氨酸产生突变体微生物来产生L-组氨酸。 突变体对泛醌生物合成的前体具有抗性。 L-组氨酸在培养液中积聚并从中回收。