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31.发明授权公开(公告)号：US08538538B2
公开(公告)日：2013-09-17
申请号：US12829108
申请日：2010-07-01
IPC分类号： A61N1/05
CPC分类号： A61N1/3605 , A61N1/0534 , A61N1/0553 , A61N1/36017 , A61N1/36025 , A61N1/37247
摘要： This disclosure describes delivery of omnipolar electrical stimulation with an external electrical stimulator. Omnipolar electrical stimulation may involve stimulation with an electrode carried on the housing of an implantable medical device (IMD) while substantially simultaneously delivering stimulation via one or more implanted electrodes having the same polarity as the electrode on the housing. An external medical device (EMD) may simulate the IMD housing electrode with an electrode separate from the electrodes carried on leads implanted near target tissue. This electrode may be an external electrode carried on the external housing of the EMD or an external patch electrode. Alternatively, the electrode may be an implantable electrode coupled to the EMD. The conductivity of the external or implantable electrode may also be optimized to approximate the conductivity of the IMD housing electrode. This electrode coupled to the EMD may be utilized during trial stimulation or chronic, external, stimulation.
摘要翻译： 本公开描述了用外部电刺激器递送全极电刺激。 全极性电刺激可涉及利用携带在可植入医疗装置（IMD）的壳体上的电极进行刺激，同时通过一个或多个与壳体上的电极极性相同的注入电极输送刺激。 外部医疗设备（EMD）可以模拟IMD外壳电极，其中电极与植入靶组织附近的导线上携带的电极分开。 该电极可以是承载在EMD的外壳上的外部电极或外部贴片电极。 或者，电极可以是耦合到EMD的可植入电极。 外部或可植入电极的导电性也可以被优化以接近IMD外壳电极的导电性。 耦合到EMD的该电极可以在试验刺激或慢性，外部刺激期间使用。
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32.发明授权Multi-stage testing of electrodes of implantable medical device, system and method 有权可植入医疗器械电极的多级测试，系统和方法公开(公告)号：US08195294B2
公开(公告)日：2012-06-05
申请号：US12112460
申请日：2008-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/36521 , A61N1/36185 , A61N1/37247
摘要： Method, controller and system for an implantable medical device capable of delivering therapeutic stimulation through a plurality of electrodes. A control module is operable to conduct a plurality of measurements of impedance values creating a plurality of measured impedance values for a plurality of selected sets of individual ones of the plurality of electrodes based on a plurality of active parameters. The control module conducts the plurality of measurements of impedance values in a plurality of stages in which at least one of said plurality of active parameters is varied between individual ones of the plurality of stages.
摘要翻译： 一种能够通过多个电极传递治疗刺激的可植入医疗装置的方法，控制器和系统。 控制模块可操作以基于多个有效参数进行阻抗值的多个测量，从而产生多个选定组的多个电极中的多个测量的阻抗值。 所述控制模块在所述多个级中的各个阶段之间变化所述多个有效参数中的至少一个有效参数的多个级中进行阻抗值的多个测量。
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33.发明申请FLAGGING OF ELECTRODES OF AN IMPLANTABLE MEDICAL DEVICE, CONTROLLER, SYSTEM AND METHOD THEREFORE 有权可植入医疗装置的电极的标记，控制器，系统和方法公开(公告)号：US20090276010A1
公开(公告)日：2009-11-05
申请号：US12112612
申请日：2008-04-30
IPC分类号： A61N1/08
CPC分类号： A61N1/08 , A61N1/36071 , A61N1/36185
摘要： Method, controller and system for an implantable medical device having a plurality of electrodes, the implantable medical device capable of delivering therapeutic stimulation to a patient, comprising a control module, a user interface operatively coupled to the control module, the user interface providing control of the control module by a medical professional or other user, and an electrode interface operatively coupled between the plurality of electrodes and the control module. The control module uses the electrode interface to obtain a plurality of measurements of impedance values for a plurality of selected pairs of individual ones of the plurality of electrodes. The control module flags electrodes using the plurality of measurements of impedance values of the selected pairs of individual ones of the plurality of electrodes comparative to a range, and the delivery of therapy on flagged electrodes is inhibited.
摘要翻译： 用于具有多个电极的可植入医疗装置的方法，控制器和系统，所述可植入医疗装置能够向患者递送治疗刺激，所述可植入医疗装置包括控制模块，可操作地耦合到所述控制模块的用户界面，所述用户界面提供 医疗专业人员或其他用户的控制模块以及可操作地耦合在多个电极和控制模块之间的电极接口。 所述控制模块使用所述电极接口来获得所述多个电极中的多个所选择的对中的多个所选对的多个测量值。 控制模块使用多个电极中所选择的多个电极对的多个阻抗值的测量来标记电极，与一个范围相比较，并且禁止在标记的电极上进行治疗。
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公开(公告)号：US09320901B2
公开(公告)日：2016-04-26
申请号：US12769149
申请日：2010-04-28
CPC分类号： A61N1/36082 , A61N1/08 , A61N1/36071
摘要： This disclosure describes techniques that support delivering electrical stimulation current via at least two user-selected electrodes of an implantable medical device (IMD) and automatically delivering balancing current below via at least one non-selected electrode. Balancing currents delivered via the at least one non-selected electrode may be configured with an amplitude below a perception threshold of a patient. Delivery of balancing current via the at least one third electrode may allow an implantable medical device to automatically balance the total current delivered to a patient.
摘要翻译： 本公开描述了支持通过可植入医疗装置（IMD）的至少两个用户选择的电极传递电刺激电流并且经由至少一个未选择的电极自动递送平衡电流的技术。 经由至少一个未选择的电极传送的平衡电流可以被配置为具有低于患者感知阈值的幅度。 通过至少一个第三电极传送平衡电流可以允许可植入医疗装置自动平衡递送给患者的总电流。
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公开(公告)号：US08744591B2
公开(公告)日：2014-06-03
申请号：US12771652
申请日：2010-04-30
申请人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Wende L. Dewing , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Brent A. Huhta
发明人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Wende L. Dewing , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Brent A. Huhta
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/372 , A61N1/37211 , A61N1/37264
摘要： This disclosure describes techniques for obtaining an image of an anatomical implant region where leads associated with an implantable medical device are implanted in a patient, manipulating the image to show lead locations and placements, performing necessary image compression and manipulations, adjusting the image to associate it with information (e.g., patient, metadata, annotations, etc.) useful to a subsequent programmer retrieving the image, and transferring a copy of the captured image to the implantable medical device. The image stored in the implantable medical device may be retrieved at a later time by a user of programmer, where the user can use the image and other associated information to program subsequent therapy.
摘要翻译： 本公开描述了用于获得解剖植入区域的图像的技术，其中与植入式医疗装置相关联的引线植入患者体内，操纵图像以显示引导位置和放置，执行必要的图像压缩和操作，调整图像以使其相关联 具有对随后的程序员检索图像有用的信息（例如，患者，元数据，注释等），以及将捕获的图像的副本传送到可植入医疗装置。 存储在可植入医疗装置中的图像可以在稍后由编程器的用户检索，其中用户可以使用图像和其他相关信息来编程后续治疗。
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36.发明授权公开(公告)号：US08571677B2
公开(公告)日：2013-10-29
申请号：US12696992
申请日：2010-01-29
IPC分类号： A61N1/00
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0551 , A61N1/0553 , A61N1/37247
摘要： This disclosure describes techniques that support delivering electrical stimulation via an electrode on a housing of an implantable medical device (IMD) while substantially simultaneously delivering electrical stimulation via one or more electrodes, having the same polarity as the electrode on the housing, on one or more leads engaged to the IMD. The stimulation may be constant current-based or constant voltage-based stimulation in the form of pulses or continuous waveforms. Delivery of stimulation via both a housing anode and one or more lead anodes, for example, may allow a user to control current paths between the housing electrode and the lead electrode(s) in a relative manner to achieve different electric or stimulation field shapes.
摘要翻译： 本公开描述了支持通过可植入医疗装置（IMD）的壳体上的电极传送电刺激的技术，同时基本上同时通过一个或多个电极（其具有与壳体上的电极相同的极性）在一个或多个 领导从事IMD。 刺激可以是以脉冲或连续波形的形式的恒定的基于电流或恒定电压的刺激。 例如，通过壳体阳极和一个或多个引线阳极传送刺激可允许用户以相对的方式控制外壳电极和引线电极之间的电流路径，以实现不同的电场或刺激场的形状。
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公开(公告)号：US08543202B2
公开(公告)日：2013-09-24
申请号：US12829089
申请日：2010-07-01
IPC分类号： A61N1/05
CPC分类号： A61N1/3605 , A61N1/0534 , A61N1/0553 , A61N1/36017 , A61N1/36025 , A61N1/37247
摘要： This disclosure describes delivery of omnipolar electrical stimulation with an external electrical stimulator. Omnipolar electrical stimulation may involve stimulation with an electrode carried on the housing of an implantable medical device (IMD) while substantially simultaneously delivering stimulation via one or more implanted electrodes having the same polarity as the electrode on the housing. An external medical device (EMD) may simulate the IMD housing electrode with an electrode separate from the electrodes carried on leads implanted near target tissue. This electrode may be an external electrode carried on the external housing of the EMD or an external patch electrode. Alternatively, the electrode may be an implantable electrode coupled to the EMD. The conductivity of the external or implantable electrode may also be optimized to approximate the conductivity of the IMD housing electrode. This electrode coupled to the EMD may be utilized during trial stimulation or chronic, external, stimulation.
摘要翻译： 本公开描述了用外部电刺激器递送全极电刺激。 全极性电刺激可涉及利用携带在可植入医疗装置（IMD）的壳体上的电极进行刺激，同时通过一个或多个与壳体上的电极极性相同的注入电极输送刺激。 外部医疗设备（EMD）可以模拟IMD外壳电极，其中电极与植入靶组织附近的导线上携带的电极分开。 该电极可以是承载在EMD的外壳上的外部电极或外部贴片电极。 或者，电极可以是耦合到EMD的可植入电极。 外部或可植入电极的导电性也可以被优化以接近IMD外壳电极的导电性。 耦合到EMD的该电极可以在试验刺激或慢性，外部刺激期间使用。
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公开(公告)号：US20110093047A1
公开(公告)日：2011-04-21
申请号：US12771652
申请日：2010-04-30
申请人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Wende L. Dewing , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Brent A. Huhta
发明人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Wende L. Dewing , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Brent A. Huhta
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/372 , A61N1/37211 , A61N1/37264
摘要： This disclosure describes techniques for obtaining an image of an anatomical implant region where leads associated with an implantable medical device are implanted in a patient, manipulating the image to show lead locations and placements, performing necessary image compression and manipulations, adjusting the image to associate it with information (e.g., patient, metadata, annotations, etc.) useful to a subsequent programmer retrieving the image, and transferring a copy of the captured image to the implantable medical device. The image stored in the implantable medical device may be retrieved at a later time by a user of programmer, where the user can use the image and other associated information to program subsequent therapy.
摘要翻译： 本公开描述了用于获得解剖植入区域的图像的技术，其中与植入式医疗装置相关联的引线植入患者体内，操纵图像以显示引导位置和放置，执行必要的图像压缩和操作，调整图像以使其相关联 具有对随后的程序员检索图像有用的信息（例如，患者，元数据，注释等），以及将捕获的图像的副本传送到可植入医疗装置。 存储在可植入医疗装置中的图像可以在稍后由编程器的用户检索，其中用户可以使用图像和其他相关信息来编程后续治疗。
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公开(公告)号：US20110093042A1
公开(公告)日：2011-04-21
申请号：US12696988
申请日：2010-01-29
CPC分类号： A61N1/37247 , A61N1/0553 , A61N1/36185 , A61N1/3756
摘要： This disclosure describes techniques that support delivering electrical stimulation via an electrode on a housing of an implantable medical device (IMD) while substantially simultaneously delivering electrical stimulation via one or more electrodes, having the same polarity as the electrode on the housing, on one or more leads engaged to the IMD. The stimulation may be constant current-based or constant voltage-based stimulation in the form of pulses or continuous waveforms. Delivery of stimulation via both a housing anode and one or more lead anodes, for example, may allow a user to control current paths between the housing electrode and the lead electrode(s) in a relative manner to achieve different electric or stimulation field shapes.
摘要翻译： 本公开描述了支持通过可植入医疗装置（IMD）的壳体上的电极传送电刺激的技术，同时基本上同时通过一个或多个电极（其具有与壳体上的电极相同的极性）在一个或多个 领导从事IMD。 刺激可以是以脉冲或连续波形的形式的恒定的基于电流或恒定电压的刺激。 例如，通过壳体阳极和一个或多个引线阳极传送刺激可允许用户以相对的方式控制外壳电极和引线电极之间的电流路径，以实现不同的电场或刺激场的形状。
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40.发明申请MULTI-STAGE TESTING OF ELECTRODES OF IMPLANTABLE MEDICAL DEVICE, SYSTEM AND METHOD 有权可植入医疗器械电极的多级测试，系统和方法公开(公告)号：US20090276007A1
公开(公告)日：2009-11-05
申请号：US12112460
申请日：2008-04-30
IPC分类号： A61N1/08
CPC分类号： A61N1/36521 , A61N1/36185 , A61N1/37247
摘要： Method, controller and system for an implantable medical device capable of delivering therapeutic stimulation through a plurality of electrodes. A control module is operable to conduct a plurality of measurements of impedance values creating a plurality of measured impedance values for a plurality of selected sets of individual ones of the plurality of electrodes based on a plurality of active parameters. The control module conducts the plurality of measurements of impedance values in a plurality of stages in which at least one of said plurality of active parameters is varied between individual ones of the plurality of stages.
摘要翻译： 一种能够通过多个电极传递治疗刺激的可植入医疗装置的方法，控制器和系统。 控制模块可操作以基于多个有效参数进行阻抗值的多个测量，从而产生多个选定组的多个电极中的多个测量的阻抗值。 所述控制模块在所述多个级中的各个阶段之间变化所述多个有效参数中的至少一个有效参数的多个级中进行阻抗值的多个测量。
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