Encapsulated stent
    31.
    发明授权
    Encapsulated stent 有权
    封装支架

    公开(公告)号:US06383214B1

    公开(公告)日:2002-05-07

    申请号:US09531833

    申请日:2000-03-21

    IPC分类号: A61F206

    摘要: An encapsulated stent having a stent or structural support layer sandwiched between two biocompatible flexible layers. One preferred embodiment has a stent cover which includes a tubular shaped stent that is concentrically retained between two tubular shaped grafts comprised of expanded polytetrafluoroethylene. Another preferred embodiment has a stent graft which includes at least one stent sandwiched between the ends of two tubular shaped grafts wherein at least a portion of the grafts are unsupported by the stent. Still another embodiment includes an articulating stented graft which includes a plurality of stents spaced apart from one another at a predetermined distance wherein each stent is contained between two elongated biocompatible tubular members. The graft/stent/graft assemblies all have inseparable layers.

    摘要翻译: 具有夹在两个生物相容性柔性层之间的支架或结构支撑层的胶囊化支架。 一个优选实施例具有支架盖,其包括同心地保持在由膨胀聚四氟乙烯构成的两个管状移植物之间的管状支架。 另一优选实施例具有支架移植物,其包括夹在两个管状移植物的端部之间的至少一个支架,其中移植物的至少一部分不被支架支撑。 另一个实施例包括铰接式支架移植物,其包括以预定距离彼此间隔开的多个支架,其中每个支架包含在两个细长的生物相容性管状构件之间。 移植物/支架/移植物组件都具有不可分离的层。

    Endoluminal encapsulated stent and methods of manufacture and
endoluminal delivery
    34.
    发明授权
    Endoluminal encapsulated stent and methods of manufacture and endoluminal delivery 失效
    腔内胶囊支架及其制造方法和腔内输送

    公开(公告)号:US6004348A

    公开(公告)日:1999-12-21

    申请号:US67158

    申请日:1998-04-27

    IPC分类号: A61F2/82 A61F2/06

    摘要: An radially expandable stent-graft and method of making the same, including at least one a stent member encapsulated between at least two longitudinally expanded polytetrafluoroethylene (ePTFE) coverings. The at least one stent member has openings through wall surfaces of the stent to permit radial expansion. The at least two longitudinally expanded ePTFE coverings are circumferentially applied over the at least one stent member in their unsintered state, and sintered during application of a circumferential pressure to bond the ePTFE around and through the wall surfaces of the stent. The sintered ePTFE forms a substantially continuous, monolithic and integral encapsulation of the at least one stent. Upon radial expansion of the stent-graft, the stent and the ePTFE node-fibril microstructure radially deform. Radial deformation of the ePTFE encapsulation results in nodal elongation in the axis of radial expansion. After radial expansion of the stent-graft, a substantial bonded area remains intact and maintains the encapsulation of the stent in vivo.

    摘要翻译: 一种可径向扩张的支架移植物及其制造方法,包括至少一个封装在至少两个纵向膨胀的聚四氟乙烯(ePTFE)覆盖物之间的支架构件。 至少一个支架构件具有通过支架的壁表面的开口以允许径向膨胀。 所述至少两个纵向膨胀的ePTFE覆盖物在其未烧结状态下周向地施加在所述至少一个支架构件上,并且在施加周向压力下烧结以将ePTFE结合在支架的壁表面上并通过支架的壁表面。 烧结的ePTFE形成至少一个支架的基本上连续的,整体的和整体的包封。 在支架移植物的径向膨胀时,支架和ePTFE节点 - 原纤维微结构径向变形。 ePTFE封装的径向变形导致径向膨胀轴的节点伸长。 在支架移植物的径向膨胀之后,实质的结合区域保持完整并且将体内的支架保持在囊内。

    Fluid containing endoluminal stent
    36.
    发明授权

    公开(公告)号:US06358276B1

    公开(公告)日:2002-03-19

    申请号:US09321496

    申请日:1999-05-27

    申请人: Tarun J. Edwin

    发明人: Tarun J. Edwin

    IPC分类号: A61F206

    摘要: An endoluminal stent contains a hollow passageway for the circulation of fluids to treat vascular walls affected with malignant growths or experiencing restenosis. The hollow passageway stent can have one or a plurality of passageways and is configured in a tubular shape with numerous coils, providing an empty tubular lumen through the center of the stent to allow blood flow. The stent is connected to a removable catheter that conducts fluid to the stent. Fluid flow may be regulated by valves incorporated in either the stent and/or the catheter. The stent and catheter are connected to avoid leakage of the fluid. Cryogenic, heated or radioactive fluids are circulated through the stent to treat the affected sites. A method of delivering drugs to the vascular wall is also provided by creating a stent with porous outer walls to allow diffusion of the drug.

    Method of making expanded polytetrafluoroethylene products
    38.
    发明授权
    Method of making expanded polytetrafluoroethylene products 失效
    制造膨胀聚四氟乙烯产品的方法

    公开(公告)号:US06203735B1

    公开(公告)日:2001-03-20

    申请号:US08792780

    申请日:1997-02-03

    IPC分类号: B29C6902

    摘要: A method of shaping three-dimensional products by manipulating an expanded polytetrafluoroethylene tubular body into a desired three-dimensional conformation. The present invention entails radially expanding a longitudinally expanded polytetrafluoroethylene (ePTFE) tube to form a radially expanded ePTFE (rePTFE) tube, engaging the rePTFE tube circumferentially about a shaping mandrel, heating the assembly to a temperature below the crystalline melt point temperature, or sintering temperature, of polytetrafluoroethylene to radially shrink the diameter of the rePTFE tube into intimate contact with the shaping mandrel, and heating the assembly to a temperature above the crystalline melt point temperature of polytetrafluoroethylene to amorphously lock the microstructure of the shaped polytetrafluoroethylene body.

    摘要翻译: 通过将膨胀的聚四氟乙烯管体操纵成所需的三维构象来形成三维产品的方法。 本发明需要径向膨胀纵向膨胀的聚四氟乙烯(ePTFE)管,以形成径向膨胀的ePTFE(rePTFE)管,其在成形心轴周围接合rePTFE管,将组件加热到低于结晶熔点温度的温度,或烧结 聚四氟乙烯的温度以径向收缩rePTFE管的直径与成形心轴紧密接触,并将组件加热到高于聚四氟乙烯的结晶熔点温度的温度,以非晶态地锁定成形聚四氟乙烯体的微观结构。