Nucleic Acids Encoding Humanized Immunoglobulin That Binds Alpha4Beta7 Integrin
    31.
    发明申请
    Nucleic Acids Encoding Humanized Immunoglobulin That Binds Alpha4Beta7 Integrin 审中-公开
    编码结合α4Beta7整合素的人源化免疫球蛋白的核酸

    公开(公告)号:US20100297699A1

    公开(公告)日:2010-11-25

    申请号:US12531534

    申请日:2008-03-19

    申请人: Ping Li Marcus Graf

    发明人: Ping Li Marcus Graf

    CPC分类号: C07K16/2839 C07K2317/24

    摘要: The invention relates to an isolated nucleic acid encoding a humanized immunoglobulin that has binding specificity for α4β7 integrin and comprises the complementarity determining regions (CDRs) of mouse Act-1 antibody. The present invention further relates to an isolated nucleic acid encoding a humanized heavy chain and an isolated nucleic acid encoding a humanized light chain. The invention also relates to recombinant vectors and host cells that comprise a nucleic acid which encodes a humanized immunoglobulin, humanized immunoglobulin heavy chain or a humanized immunoglobulin light chain, and to methods of preparing a humanized immunoglobulin.

    摘要翻译: 本发明涉及编码对α4和bgr7整联蛋白具有结合特异性并包含小鼠Act-1抗体的互补决定区(CDR)的人源化免疫球蛋白的分离的核酸。 本发明还涉及编码人源化重链的分离的核酸和编码人源化轻链的分离的核酸。 本发明还涉及包含编码人源化免疫球蛋白,人源化免疫球蛋白重链或人源化免疫球蛋白轻链的核酸的重组载体和宿主细胞,以及制备人源化免疫球蛋白的方法。

    METHOD, SYSTEM, RELAY STATION AND BASE STATION FOR TRANSMITTING DATA MOBILE COMMUNICATION
    32.
    发明申请
    METHOD, SYSTEM, RELAY STATION AND BASE STATION FOR TRANSMITTING DATA MOBILE COMMUNICATION 有权
    方法,系统,移动站和基站在移动通信中传输数据

    公开(公告)号:US20100285743A1

    公开(公告)日:2010-11-11

    申请号:US12449247

    申请日:2008-01-30

    IPC分类号: H04B7/14

    摘要: A mobile communication data transmission method for a cell having one base station and more than one relay station involves switching the relay stations between at least two operating modes of signaling transmission under the control of the base station. A system transmits mobile communication data in a cell having one base station and more than one relay station. When transmitting an uplink signaling or a downlink signaling, the relay stations switch between at least two operating modes under the control of the base station. By using the method, network, relay station, and base station, data transmission in multiple modes can be achieved, so as to achieve a flexible relay scheme.

    摘要翻译: 用于具有一个基站和多于一个中继站的小区的移动通信数据传输方法包括在基站的控制下在至少两个信令传输的操作模式之间切换中继站。 系统在具有一个基站和多于一个中继站的小区中发送移动通信数据。 当发送上行链路信令或下行链路信令时,中继站在基站的控制下在至少两个操作模式之间切换。 通过使用方法,网络,中继站和基站,可以实现多种模式的数据传输,从而实现灵活的中继方案。

    INTELLIGENT ROUTING OF COORDINATED AUDIO, VIDEO, WEB SERVICES AND MEASUREMENT DATA STREAMS
    33.
    发明申请
    INTELLIGENT ROUTING OF COORDINATED AUDIO, VIDEO, WEB SERVICES AND MEASUREMENT DATA STREAMS 有权
    协调音频,视频,WEB服务和测量数据流的智能路由

    公开(公告)号:US20100235517A1

    公开(公告)日:2010-09-16

    申请号:US12720335

    申请日:2010-03-09

    IPC分类号: G06F15/16

    摘要: A system may receive a request from a client station to communicate with any available expert that matches at least one criterion. The system determines an identity of an expert station associated with an expert matching the at least one criterion. The system may then establish a session between the client station and the expert station, where the session includes a first connection and a second connection, the first connection is for transmission of audio/video, and the second connection is for transmission of telemetry data during the transmission of the audio/video. The telemetry data is measured at the client station.

    摘要翻译: 系统可以从客户端接收到与至少一个标准匹配的任何可用专家通信的请求。 系统确定与与至少一个标准相匹配的专家相关联的专家站的身份。 然后,系统可以在客户端站和专家站之间建立会话,其中会话包括第一连接和第二连接,第一连接用于音频/视频的传输,第二连接用于在遥控数据期间传输遥测数据 传输音频/视频。 在客户端测量遥测数据。

    14-3-3 Zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer type
    34.
    发明授权
    14-3-3 Zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer type 失效
    14-3-3 Zeta过表达作为不良预后因素,是多种癌症类型的治疗靶点

    公开(公告)号:US07709205B2

    公开(公告)日:2010-05-04

    申请号:US11950264

    申请日:2007-12-04

    IPC分类号: C12Q1/68

    摘要: Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.

    摘要翻译: 公开了确定患有过度增生性疾病的受试者的预后的方法,包括确定受试者中14-3-3ζ的表达和/或功能。 还公开了制备调节凋亡的药剂的方法,包括获得一种或多种候选物的步骤,测试一种或多种候选物质以确定其调节14-3-3ζ的表达和/或功能的能力, 选择确定调节14-3-3ζ的表达和/或功能的候选物质,并制备包含所选候选物质的药物组合物。 此外,公开了通过本发明所述的方法制备药剂并且将药剂施用于受试者的治疗患有过度​​增殖性疾病的受试者的方法。 过度增生性疾病可以是癌症,例如乳腺癌。

    Apparatus and method for presenting data and sending a message
    37.
    发明授权
    Apparatus and method for presenting data and sending a message 有权
    用于呈现数据和发送消息的装置和方法

    公开(公告)号:US07526529B2

    公开(公告)日:2009-04-28

    申请号:US11142342

    申请日:2005-06-02

    IPC分类号: G06F15/16

    摘要: An apparatus and method for receiving relevant data, presenting the relevant data to users, and enabling users to construct and route an outgoing message. Using this apparatus and method, hospitals can provide efficient and personalized service by viewing up-to-date information about each admitted patient and, if necessary, routing relevant portions of the information, via a text message, to those responsible for patient care.

    摘要翻译: 一种用于接收相关数据的装置和方法,向用户呈现相关数据,并使用户能够构建和路由一个外发消息。 使用这种设备和方法,医院可以通过查看关于每个被接纳的患者的最新信息来提供有效和个性化的服务,并且如果需要,通过文本消息将信息的相关部分路由到负责患者护理的那些人。

    Hardware and Software Co-test Method for FPGA
    38.
    发明申请
    Hardware and Software Co-test Method for FPGA 审中-公开
    FPGA的硬件和软件协同测试方法

    公开(公告)号:US20090100304A1

    公开(公告)日:2009-04-16

    申请号:US12238674

    申请日:2008-09-26

    IPC分类号: G01R31/3177 G06F11/25

    CPC分类号: G01R31/318516

    摘要: A hardware and software co-test method for FPGA comprises the following steps of: setting up a HW/SW co-test system comprising a PC, a software part, HW/SW communication modules, a hardware accelerator for testing a DUT FPGA which is mapped with a configuration file of DUT; predefining a table of test vectors for FPGA by software part in PC; generating configuration files based on the tables of test vector for I/O module, CLB and routing matrix, and then sending the configuration file into DUT FPGA to configure the FPGA; testing DUT FPGA in terms of the tables of test vector for lo I/O module, CLB and routing matrix, and returning results to the software part; and comparing the test results with expected data in the software part, generating a test report, and during the above steps, the error cells in the FPGA are capable of being automatically positioned.

    摘要翻译: FPGA的硬件和软件协同测试方法包括以下步骤:建立包括PC,软件部分,HW / SW通信模块,用于测试DUT FPGA的硬件加速器的HW / SW协同测试系统, 用DUT的配置文件映射; 通过PC中的软件部分预先定义FPGA测试向量表; 根据I / O模块,CLB和路由矩阵的测试向量表生成配置文件,然后将配置文件发送到DUT FPGA配置FPGA; 根据Lo I / O模块,CLB和路由矩阵的测试向量表,测试DUT FPGA,并将结果返回到软件部分; 并将测试结果与软件部分中的预期数据进行比较,生成测试报告,并且在上述步骤中,FPGA中的错误单元能够自动定位。