摘要:
The invention relates to an isolated nucleic acid encoding a humanized immunoglobulin that has binding specificity for α4β7 integrin and comprises the complementarity determining regions (CDRs) of mouse Act-1 antibody. The present invention further relates to an isolated nucleic acid encoding a humanized heavy chain and an isolated nucleic acid encoding a humanized light chain. The invention also relates to recombinant vectors and host cells that comprise a nucleic acid which encodes a humanized immunoglobulin, humanized immunoglobulin heavy chain or a humanized immunoglobulin light chain, and to methods of preparing a humanized immunoglobulin.
摘要:
A mobile communication data transmission method for a cell having one base station and more than one relay station involves switching the relay stations between at least two operating modes of signaling transmission under the control of the base station. A system transmits mobile communication data in a cell having one base station and more than one relay station. When transmitting an uplink signaling or a downlink signaling, the relay stations switch between at least two operating modes under the control of the base station. By using the method, network, relay station, and base station, data transmission in multiple modes can be achieved, so as to achieve a flexible relay scheme.
摘要:
A system may receive a request from a client station to communicate with any available expert that matches at least one criterion. The system determines an identity of an expert station associated with an expert matching the at least one criterion. The system may then establish a session between the client station and the expert station, where the session includes a first connection and a second connection, the first connection is for transmission of audio/video, and the second connection is for transmission of telemetry data during the transmission of the audio/video. The telemetry data is measured at the client station.
摘要:
Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.
摘要:
A process for removing DOC (dissolved organic carbon) from a concentrated salt solution containing DOC by contacting the salt solution with a coagulant/flocculant such that the DOC becomes insoluble and removing the insoluble DOC from the salt solution.
摘要:
An apparatus and method for receiving relevant data, presenting the relevant data to users, and enabling users to construct and route an outgoing message. Using this apparatus and method, hospitals can provide efficient and personalized service by viewing up-to-date information about each admitted patient and, if necessary, routing relevant portions of the information, via a text message, to those responsible for patient care.
摘要:
A hardware and software co-test method for FPGA comprises the following steps of: setting up a HW/SW co-test system comprising a PC, a software part, HW/SW communication modules, a hardware accelerator for testing a DUT FPGA which is mapped with a configuration file of DUT; predefining a table of test vectors for FPGA by software part in PC; generating configuration files based on the tables of test vector for I/O module, CLB and routing matrix, and then sending the configuration file into DUT FPGA to configure the FPGA; testing DUT FPGA in terms of the tables of test vector for lo I/O module, CLB and routing matrix, and returning results to the software part; and comparing the test results with expected data in the software part, generating a test report, and during the above steps, the error cells in the FPGA are capable of being automatically positioned.
摘要:
Pharmaceutical concentrate formulations comprising 2-amino-1,3-propanediol compounds, analogs thereof and salts thereof, particularly 2-amino-2-[2-(4-octylphenyl)ethyl]-propane-1,3-diol or a pharmaceutically acceptable salt thereof in an organic solvent or semi-aqueous solvent and methods for administration of the undiluted and diluted concentrate are provided.
摘要:
A spontaneously dispersible pharmaceutical composition comprising a poorly soluble drug and a carrier medium comprising (1) a lipophilic component, (2) a surfactant, and optionally (3) a hydrophilic component, wherein at least one of the components (1) to (3) is solid at room temperature. A particularly useful hydrophilic component in the system is a polymer that is solid at room temperature, e.g., solid PEG.