PHARMACEUTICAL COMPOSITIONS
    5.
    发明申请
    PHARMACEUTICAL COMPOSITIONS 审中-公开
    药物组合物

    公开(公告)号:US20130245061A1

    公开(公告)日:2013-09-19

    申请号:US13989250

    申请日:2011-12-01

    IPC分类号: C07D471/04

    摘要: A pharmaceutical composition for the oral administration of a therapeutic compound of formula (I), comprising granules that comprise at least therapeutic compound of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt, or a hydrate or solvate thereof; at least one non-ionic surfactant that is Vitamin E-TPGS in an amount ranging from about 15 to about 80% by weight of the composition; and at least one a dissolution enhancing agent selected from polyethylene glycol, polyethylene oxide, and any combination of the foregoing; processes for making such pharmaceutical compositions; a kit comprising such pharmaceutical composition and the instructions for administration thereof; and related uses and methods of treatment.

    摘要翻译: 口服给药式(I)治疗性化合物的药物组合物,其包含至少包含治疗性式(I)化合物或其互变异构体或其药学上可接受的盐或其水合物或溶剂合物的颗粒剂; 至少一种非离子表面活性剂,其量为所述组合物的约15至约80重量%的量的维生素E-TPGS; 和至少一种选自聚乙二醇,聚环氧乙烷和前述的任何组合的溶解增强剂; 制备这种药物组合物的方法; 包含该药物组合物的试剂盒及其施用说明书; 及相关用途及治疗方法。

    Systems and methods for signaling for semi-static configuration in grant-free uplink transmissions

    公开(公告)号:US11516826B2

    公开(公告)日:2022-11-29

    申请号:US16544274

    申请日:2019-08-19

    摘要: Methods and systems are provided for signaling for semi-static configuration in grant free uplink transmissions. Radio resource control (RRC) signaling is used to provide information from a base station to a user equipment (UE) that configure the grant free transmission resource to be used by the UE. In some implementations, the RRC signaling may be used in conjunction with system information that is transmitted to all UEs and/or Downlink Control Information (DCI) that the UE needs to access subsequent to the RRC signaling. In some implementations, the DCI includes an activation or deactivation indicator that the UE monitors to determine when the UE is allowed to transmit to the BS or should stop transmitting. Implementations allow for grant free transmission resources to be configured on an individual user based and a group basis.

    Methods and apparatus for sidelink communications and resource allocation

    公开(公告)号:US11044748B2

    公开(公告)日:2021-06-22

    申请号:US16392827

    申请日:2019-04-24

    IPC分类号: H04W72/14 H04W4/40 H04W72/12

    摘要: A user equipment (UE) receives a message that indicates a sidelink (SL) communication resource configuration to be used by the UE for communicating SL control information and SL data between the UE and another UE. The UE transmits SL control information according to the SL communication resource configuration, and transmits SL data according to the SL communication resource configuration. The SL control information and the SL data are transmitted by the UE without the UE receiving, in a downlink control information (DCI), a grant of communication resources.

    HARQ systems and methods for grant-free uplink transmissions

    公开(公告)号:US10651980B2

    公开(公告)日:2020-05-12

    申请号:US16151920

    申请日:2018-10-04

    申请人: Yu Cao Liqing Zhang

    发明人: Yu Cao Liqing Zhang

    IPC分类号: H04L1/18 H04L1/00

    摘要: Systems and methods are disclosed for performing hybrid automatic repeat request (HARQ) for grant-free uplink transmissions. Some of the systems and methods disclosed herein may address problems such as how to perform acknowledgement (ACK) and/or negative acknowledgement (NACK), how to determine and signal retransmission timing, how to determine the transmission/retransmission attempt and the redundancy version (RV), and/or how to perform the HARQ combining.