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公开(公告)号：US07670828B2
公开(公告)日：2010-03-02
申请号：US11499705
申请日：2006-08-07
CPC分类号： C12N15/1034 , C07K14/395 , C12C12/004 , C12C12/006 , C12N1/18 , C12P7/06 , C12Q1/6895 , C12Q2600/156 , C12Q2600/158 , Y02E50/17
摘要： Provided herein are a method for selecting a gene participating in the desired brewing character and compiling a database of the whole genome sequence of industrial yeast; identifying a gene participating in a brewing characteristic from the database; functional analysis of the gene; and a DNA array of the whole genome sequences of an industrial yeast. Also provided are a method for yeast breeding; a method of producing an alcoholic beverage with improved quality; and a screening method to identify genes that increase productivity and/or improve flavor in the production of an alcohol or an alcoholic beverage by (A) analyzing a whole industrial yeast genome sequence, (B) comparing the genome sequence with the genome sequence of S. cerevisiae, (C) selecting a gene of the industrial yeast encoding having 70 to 97% identity to an amino acid sequence of S. cerevisiae; and (D) analyzing the selected gene.
摘要翻译： 本文提供了选择参与所需酿造性状的基因并编辑工业酵母的全基因组序列的数据库的方法; 从数据库中鉴定参与酿造特性的基因; 基因的功能分析; 以及工业酵母的全基因组序列的DNA阵列。 还提供了酵母育种的方法; 一种生产具有提高质量的酒精饮料的方法; （A）分析整个工业酵母基因组序列，（B）将基因组序列与S基因组序列进行比较，鉴定提高生产力和/或改善酒精或酒精饮料生产风味的基因的筛选方法 （C）选择与酿酒酵母的氨基酸序列具有70〜97％同一性的工业酵母的基因; 和（D）分析所选择的基因。
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公开(公告)号：US20090304858A1
公开(公告)日：2009-12-10
申请号：US11988739
申请日：2006-08-08
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
IPC分类号： C12G1/00 , C07H21/04 , C07H21/00 , C07K14/00 , C12N15/74 , C12N1/16 , C12Q1/68 , G01N33/53 , C12C11/00 , C12G1/022 , A23L1/28 , C12G1/04
CPC分类号： C12N9/0051
摘要： The present invention relates to a brewery yeast having controlled sulfite-producing capability, a process for producing alcoholic beverages with controlled sulfite amount. More particularly, the present invention relates to a yeast whose sulfite-producing capability that contribute to the product flavor is controlled by controlling the expression level of MET16 gene encoding brewery yeast phosphoadenylyl sulfate reductase Met16p, particularly non-ScMET16 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with said yeast.
摘要翻译： 本发明涉及具有受控亚硫酸盐生产能力的啤酒酵母，一种生产受控亚硫酸盐含量的酒精饮料的方法。 更具体地说，本发明涉及通过控制编码啤酒厂酵母磷酸腺苷酸硫酸还原酶Met16p的MET16基因，特别是对大啤酒酵母特异性的非ScMET16基因的表达水平来控制有助于产品香味的亚硫酸盐产生能力的酵母， 以及用所述酵母生产酒精饮料的方法。
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公开(公告)号：US20090233278A1
公开(公告)日：2009-09-17
申请号：US11887117
申请日：2006-09-12
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
IPC分类号： C12Q1/68 , C07H21/00 , C07H21/04 , C07H21/02 , C12N9/10 , C12N15/63 , C12N1/19 , C12Q1/02 , C12C11/09 , C12C11/00 , C12G1/022 , C12H1/14
CPC分类号： C12N9/1096 , C12P7/16 , C12P7/62 , C12R1/865 , Y02E50/10
摘要： The present invention relates to a branched-chain amino acid aminotransferase gene and a use thereof, particularly, to a brewery yeast for producing alcoholic drinks with enhanced flavor, to alcoholic drinks produced with said yeast and to a method for producing said drinks. More particularly, the present invention relates to a yeast whose capacity of producing amyl alcohol and/or isobutanol and/or isoamyl acetate that contribute to the product flavor is controlled by controlling the expression levels of BAT1 and BAT2 genes coding for brewery yeast branched-chain amino acid aminotransferases Bat1p and Bat2p, respectively, particularly nonScBAT1 or nonScBAT2 gene specific to lager brewing yeast, and to a method for producing alcoholic drinks using said yeast.
摘要翻译： 本发明涉及一种支链氨基酸氨基转移酶基因及其用途，特别是涉及用于生产具有增强的风味的酒精饮料的啤酒酵母，用所述酵母生产的酒精饮料以及所述饮料的制备方法。 更具体地，本发明涉及通过控制编码啤酒酵母支链的BAT1和BAT2基因的表达水平来控制有助于产品风味的生产戊醇和/或异丁醇和/或乙酸异戊酯的能力的酵母 氨基酸氨基转移酶Bat1p和Bat2p，特别是对大啤酒酵母特异性的nonScBAT1或nonScBAT2基因，以及使用所述酵母生产酒精饮料的方法。
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34.发明申请Solid-state image pickup device and electronic device comprising the same 审中-公开固态图像拾取装置和包括该固态图像拾取装置的电子装置公开(公告)号：US20090153707A1
公开(公告)日：2009-06-18
申请号：US12316394
申请日：2008-12-12
申请人： Yoshihiro Nakao
发明人： Yoshihiro Nakao
IPC分类号： H04N5/335
CPC分类号： G02B27/0006 , G02B7/021 , H04N5/2254 , H04N5/2257
摘要： A camera module 100 comprises at the bottom of a lens unit 4, a flange unit 43 being extended beyond a contact portion C between the lens unit 4 and a lens holder 3. Debris D produced by contact between the lens holder 3 and the lens unit 4 is collected on the flange unit 43. This can prevent poor imaging caused by the debris D. Therefore, it is possible to provide a simply-configured camera module 100 in which poor imaging due to debris is prevented but miniaturization is not hindered.
摘要翻译： 相机模块100包括在透镜单元4的底部，凸缘单元43延伸超过透镜单元4和透镜保持器3之间的接触部分C.通过透镜保持器3和透镜单元之间的接触而产生的碎屑D 这可以防止由碎屑D引起的不良成像。因此，可以提供简单配置的相机模块100，其中防止由于碎片造成的不良成像，但是小型化不受阻碍。
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公开(公告)号：US20090148555A1
公开(公告)日：2009-06-11
申请号：US11988453
申请日：2006-08-11
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
CPC分类号： C12N9/88
摘要： The present invention relates to an dihydroxy-acid dehydratase gene and use thereof, in particular, a brewery yeast for producing alcoholic beverages having superior flavor, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast whose level of producing total vicinal diketones, especially level of producing diacetyl, that are responsible off-flavor of the product, is reduced by amplifying the expression level of ILV3 gene encoding brewery yeast dihydroxy-acid dehydratase ILV3p, particularly non-ScILV3 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with said yeast.
摘要翻译： 本发明涉及二羟基酸脱水酶基因及其用途，特别是用于生产具有优良风味的酒精饮料的啤酒酵母，用所述酵母生产的酒精饮料及其制备方法。 更具体地，本发明涉及通过扩增编码啤酒酵母二羟基酸的ILV3基因的表达水平来降低产生负责产品脱味的总连位二酮，特别是产生二乙酰水平的水平的酵母 脱水酶ILV3p，特别是对大型酿造酵母特异性的非scILV3基因，以及用所述酵母生产酒精饮料的方法。
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公开(公告)号：US20090130255A1
公开(公告)日：2009-05-21
申请号：US11919226
申请日：2006-12-22
CPC分类号： C12C12/006 , C12C12/004 , C12G1/0203 , C12N9/0065 , C12Y111/01006
摘要： The present invention relates to a gene encoding a catalase and use thereof, in particular, a brewery yeast having high sulfite-producing capability, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast, whose capability of producing sulfite, that contribute to stability of flavor in products, is enhanced by amplifying expression level of CTT1 gene encoding a catalase Ctt1p, especially non-ScCTT1 gene or ScCTT1 gene specific to a lager brewing yeast, and to a method for producing alcoholic beverages with said yeast.
摘要翻译： 本发明涉及编码过氧化氢酶的基因及其用途，特别是具有高亚硫酸盐生产能力的啤酒酵母，用该酵母生产的酒精饮料及其制造方法。 更具体地，本发明涉及通过扩增编码过氧化氢酶Ctt1p的CTT1基因，特别是非ScCTT1基因或ScCTT1基因特异性的ScCTT1基因的表达水平来提高其产生亚硫酸盐的能力，其有助于产品中风味稳定性的酵母 啤酒酿造酵母，以及用所述酵母生产酒精饮料的方法。
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37.发明申请Gene Encoding Protein Responsible for Flocculation Property of Yeast and Use Thereof 审中-公开负责酵母絮凝性能的基因编码蛋白及其应用公开(公告)号：US20090074913A1
公开(公告)日：2009-03-19
申请号：US11918496
申请日：2006-12-27
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
CPC分类号： C07K14/395
摘要： The present invention relates to a gene encoding a protein responsible for flocculation property of yeast and use thereof, in particular, a brewery yeast with appropriate flocculation property for producing desired alcoholic beverages, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast to which suitable flocculation property for brewing desired alcoholic beverages was imparted by controlling expression level of MHP1 gene encoding a protein responsible for flocculation property of brewery yeast, especially non-ScMHP1 gene specific to a lager brewing yeast, to alcoholic beverages produced with said yeast and to a method for producing said beverages.
摘要翻译： 本发明涉及编码负责酵母的絮凝性的蛋白质及其用途的基因，特别是具有适当的絮凝性的酿造酵母，用于生产所需的酒精饮料，用所述酵母生产的酒精饮料，以及所述饮料的制造方法 。 更具体地，本发明涉及通过控制编码负责啤酒酵母的絮凝特性的蛋白质的MHP1基因的表达水平，特别是对大啤酒特异性的非ScMHP1基因来赋予用于酿造所需酒精饮料的合适的絮凝性能的酵母 酵母，用所述酵母生产的酒精饮料和生产所述饮料的方法。
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公开(公告)号：US20090053360A1
公开(公告)日：2009-02-26
申请号：US12279210
申请日：2007-02-01
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
CPC分类号： C12G1/0203 , C12C12/004 , C12C12/006 , C12N1/04 , C12N9/1051
摘要： The present invention relates to a gene encoding glycogen synthase and use thereof, in particular, a yeast for practical use with superior resistance property to dryness and/or low-temperature storage, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast, whose resistance property to dryness and/or resistance property to low-temperature storage is enhanced by amplifying expression level of GSY1 or GSY2 gene encoding a Gsy1p or Gsy2p which is a glycogen synthase in brewer's yeast, especially non-ScGSY1 gene or non-ScGSY2 gene specific to a lager brewing yeast and to a method for producing alcoholic beverages with said yeast, etc.
摘要翻译： 本发明涉及编码糖原合成酶的基因及其用途，特别是具有优异的耐干燥性和/或低温储存性的实际用途的酵母，所述酵母生产的酒精饮料及其制备方法 。 更具体地说，本发明涉及通过扩增酿酒酵母中作为糖原合成酶的Gsy1p或Gsy2p的GSY1或GSY2基因的表达水平来提高其耐低温性和耐耐性的酵母， ，特别是对于大型酿造酵母特异性的非ScGSY1基因或非ScGSY2基因，以及用所述酵母等生产酒精饮料的方法。
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公开(公告)号：US20090047381A1
公开(公告)日：2009-02-19
申请号：US12278995
申请日：2006-12-05
申请人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
发明人： Yoshihiro Nakao , Yukiko Kodama , Tomoko Shimonaga
CPC分类号： C07K14/705 , C12C12/004 , C12C12/006 , C12G1/0203
摘要： The present invention relates to ammonia transporter genes and use thereof. The invention relates in particular to a brewer's yeast which shows enhanced ammonia assimilation, alcoholic beverages produced using such yeast, and a method of producing such alcoholic beverages. More specifically, the invention relates to the MEP1 gene which codes for the ammonia transporter Mep1 in brewer's yeast, particularly to a yeast which can control the ammonia assimilation ability by controlling the level of expression of the nonScMEP1 gene or ScMEP1 gene characteristic to beer yeast and to a method of producing alcoholic beverages using such yeast.
摘要翻译： 本发明涉及氨转运蛋白基因及其应用。 本发明特别涉及显示增强的氨同化的酿酒酵母，使用这种酵母生产的含酒精饮料，以及生产这种酒精饮料的方法。 更具体地说，本发明涉及编码啤酒酵母中的氨转运蛋白Mep1的MEP1基因，尤其涉及通过控制啤酒酵母特有的nonScMEP1基因或ScMEP1基因的表达水平来控制氨同化能力的酵母， 涉及使用这种酵母生产酒精饮料的方法。
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公开(公告)号：US07365164B2
公开(公告)日：2008-04-29
申请号：US11499703
申请日：2006-08-07
IPC分类号： C07K14/39 , C07K14/395
CPC分类号： C12N15/1034 , C07K14/395 , C12C12/004 , C12C12/006 , C12N1/18 , C12P7/06 , C12Q1/6895 , C12Q2600/156 , C12Q2600/158 , Y02E50/17
摘要： Provided herein are a method for selecting a gene participating in the desired brewing character and compiling a database of the whole genome sequence of industrial yeast; identifying a gene participating in a brewing characteristic from the database; functional analysis of the gene; and a DNA array of the whole genome sequences of an industrial yeast. Also provided are a method for yeast breeding; a method of producing an alcoholic beverage with improved quality; and a screening method to identify genes that increase productivity and/or improve flavor in the production of an alcohol or an alcoholic beverage by (A) analyzing a whole industrial yeast genome sequence, (B) comparing the genome sequence with the genome sequence of S. cerevisiae, (C) selecting a gene of the industrial yeast encoding having 70 to 97% identity to an amino acid sequence of S. cerevisiae; and (D) analyzing the selected gene.
摘要翻译： 本文提供了选择参与所需酿造性状的基因并编辑工业酵母的全基因组序列的数据库的方法; 从数据库中鉴定参与酿造特性的基因; 基因的功能分析; 以及工业酵母的全基因组序列的DNA阵列。 还提供了酵母育种的方法; 一种生产具有提高质量的酒精饮料的方法; （A）分析整个工业酵母基因组序列，（B）将基因组序列与S基因组序列进行比较，鉴定提高生产力和/或改善酒精或酒精饮料生产风味的基因的筛选方法 （C）选择与酿酒酵母的氨基酸序列具有70〜97％同一性的工业酵母的基因; 和（D）分析所选择的基因。
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