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公开(公告)号：US09856153B2
公开(公告)日：2018-01-02
申请号：US15302618
申请日：2015-04-10
Applicant: Trojan Technologies
Inventor： Douglas Penhale
Abstract: There is disclosed a coupling for a radiation source assembly that comprises an elongate radiation source and an elongate radiation transparent protective sleeve for receiving the elongate radiation source. The coupling disengages in two stages when it is desired to remove the elongate radiation source for servicing (or any other purpose). The coupling is disengaged from a first position in which a seal is made between the sleeve bolt element and the lamp plug element. When this action takes place, the lamp plug element is still secure with respect to the sleeve bolt element but since there is no seal between the two, any fluid which has flooded the elongate radiation source (e.g., due to breakage or other damage to the protective sleeve) will emerge from the coupling warning the operator not to fully disengage the lamp plug element from the sleeve bolt element. If no such fluid is seen by operator, the operator may continue to disengage the lamp plug element from the sleeve bolt element to withdraw the elongate radiation source from the elongate radiation transparent protective sleeve.
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公开(公告)号：US20170232368A1
公开(公告)日：2017-08-17
申请号：US15503532
申请日：2015-08-13
Applicant: TROJAN TECHNOLOGIES
Inventor： Kai Viggo Sandvik , Tor Olav Lyng , Dusko Antonio Kezele
CPC classification number: B01D33/463 , B01D33/04 , B01D33/50 , B01D2201/081
Abstract: There is described is a belt cleaning blow-off device having a streamlined inner surface. In one embodiment a fluid outlet nozzle is connectable to a conduit of a blow-off device for cleaning a belt filter. The nozzle comprises a housing having an inner surface and outer surface, wherein the inner surface defines a fluid entry zone to receive fluid into the nozzle and an elongated gap for directing fluid towards the belt. The inner surface is streamlined to facilitate flow of the fluid into the gap. In a second embodiment, the blow-off device comprises a housing connectable to a fluid source and having an inner and outer surface. The housing defines a conduit for transporting the fluid within a channel, wherein the inner surface defines a surface of the channel and an elongated gap for directing the fluid towards the belt. The inner surface is streamlined and typically teardrop-shaped to facilitate flow of the fluid into the gap.
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33.发明授权公开(公告)号：US09567243B2
公开(公告)日：2017-02-14
申请号：US13386615
申请日：2010-07-23
Applicant: Joseph Elku , Douglas Penhale
Inventor： Joseph Elku , Douglas Penhale
CPC classification number: C02F1/325 , C02F2201/3225 , C02F2201/3227 , C02F2201/324
Abstract: There is disclosed a cleaning apparatus for a radiation source assembly in a fluid treatment system. The clean apparatus comprises a cleaning sleeve moveable to remove fouling materials from an exterior portion of the radiation source assembly, the cleaning sleeve comprising at least one chamber for receiving a cleaning fluid and a cleaning sleeve inlet in fluid communication with the at least one chamber and a first conduit element for conveying the cleaning fluid to the cleaning sleeve inlet, the first conduit element being configured such that a distal portion of the first conduit element is in fluid communication with the cleaning sleeve inlet and a proximal portion of the first conduit element is disposed outside of fluid being treated in the fluid treatment system.
Abstract translation: 公开了一种用于流体处理系统中的辐射源组件的清洁装置。 清洁装置包括可移动以从辐射源组件的外部部分去除结垢材料的清洁套筒，所述清洁套筒包括用于接收清洁流体的至少一个腔室和与所述至少一个腔室流体连通的清洁套筒入口， 用于将清洁流体输送到清洁套筒入口的第一管道元件，第一管道元件构造成使得第一管道元件的远端部分与清洁套筒入口流体连通，并且第一管道元件的近端部分是 设置在流体处理系统中被处理的流体外部。
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公开(公告)号：US09539351B2
公开(公告)日：2017-01-10
申请号：US13994941
申请日：2011-12-13
Applicant: George Traubenberg , Douglas Penhale
Inventor： George Traubenberg , Douglas Penhale
CPC classification number: A61L2/10 , C02F1/325 , C02F2201/3225 , C02F2201/3227 , C02F2201/324 , C02F2201/328
Abstract: There is described a radiation source module for use in a fluid treatment system. The radiation source module comprises: a housing having an inlet, an outlet and a fluid treatment zone disposed between. The fluid treatment zone comprises a first wall surface and a second wall surface interconnected by a floor surface. The first wall surface, the second wall surface and the floor surface are configured to receive a flow of fluid through the fluid treatment zone. The radiation source module further comprises at least one radiation source assembly secured with respect to the first wall surface and the second wall surface and a module motive coupling element connected to the housing and configured to be coupled to a module motive element to permit the radiation source module to be installed in and extracted from the fluid treatment system. A fluid treatment system comprising the radiation source module is also described.
Abstract translation: 描述了用于流体处理系统的辐射源模块。 辐射源模块包括：壳体，其具有设置在其间的入口，出口和流体处理区。 流体处理区包括由地板表面互连的第一壁表面和第二壁表面。 第一壁表面，第二壁表面和地板表面构造成接收通过流体处理区的流体流。 所述辐射源模块还包括相对于所述第一壁表面和所述第二壁表面固定的至少一个辐射源组件和连接到所述壳体的模块运动耦合元件，并且被配置为耦合到模块运动元件以允许所述辐射源 模块安装在流体处理系统中并从中提取。 还描述了包括辐射源模块的流体处理系统。
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35.发明申请公开(公告)号：US20140191137A1
公开(公告)日：2014-07-10
申请号：US14115930
申请日：2012-05-07
Applicant: William Kevin O'Keefe
Inventor： William Kevin O'Keefe
CPC classification number: C02F1/325 , B08B17/00 , C02F1/66 , C02F2201/3228 , C02F2303/14 , C02F2303/20 , C02F2303/22 , C09D5/1618 , Y10T428/1359 , Y10T428/259
Abstract: An element having an immersible portion for contact with an aqueous liquid, the immersible portion having a contact surface for contact with the aqueous liquid, the contact surface configured to have strong acidity, a radiation (e.g., ultraviolet radiation) source assembly, a radiation (e.g., ultraviolet radiation) source module and a fluid (e.g., water) treatment system incorporating this element applicable to any surface in contact with fluid that is susceptible to build-up of fouling materials. The embodiments obviates or mitigates the rate of accumulation of fouling on surfaces in contact with aqueous solution, such as the protective (e.g., quartz) sleeves in an ultraviolet radiation fluid treatment system, by modifying at least a portion of the surface of those sleeves in contact with fluid (e.g., water) to have an inherent strong surface acidity.
Abstract translation: 具有用于与水性液体接触的浸没部分的元件，所述浸入部分具有用于与所述水性液体接触的接触表面，所述接触表面被配置为具有强酸性，辐射（例如，紫外线辐射）源组件，辐射 例如紫外线辐射）源模块和包含该元件的流体（例如，水）处理系统，该系统适用于易于积聚污垢材料的流体接触的任何表面。 这些实施例消除或减轻与水溶液接触的表面上的污垢积聚速率，例如紫外线辐射流体处理系统中的保护（例如石英）套筒，通过将这些套筒的表面的至少一部分修改为 与流体（例如水）接触以具有固有的强表面酸度。
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Patent Agency Ranking
36.发明授权公开(公告)号：US08748112B2
公开(公告)日：2014-06-10
申请号：US13399556
申请日：2012-02-17
Applicant: Spyros Stylianou
Inventor： Spyros Stylianou
IPC: G01N33/53 , G01N33/566 , G01N33/00 , C07K14/435
CPC classification number: C07K14/43581 , A61K38/00 , C07K14/4702 , C07K2319/10
Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
Abstract translation: 本发明基于Notch信号传导途径与癌症相关的发现。 因此，本发明提供了治疗癌症的方法和组合物。 还提供了调节Notch信号传导途径中的蛋白质的表达和/或活性用于受试者的癌症诊断和治疗的方法。
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公开(公告)号：US20140008547A1
公开(公告)日：2014-01-09
申请号：US13877828
申请日：2011-10-03
Applicant: Joseph Strik , Paul De Boer
Inventor： Joseph Strik , Paul De Boer
IPC: A61L2/10
CPC classification number: A61L2/10 , C02F1/325 , C02F2201/004
Abstract: A sleeve holder assembly for a radiation source is disclosed. The sleeve holder assembly comprises: an elongate radiation transparent sleeve element; a sleeve holder receptacle portion coupled to the elongate radiation transparent sleeve element; a sleeve bolt assembly portion coupled to the sleeve holder receptacle portion; a first sealing element disposed between the sleeve holder receptacle portion and the sleeve bolt assembly portion; and a locking element configured to prevent decoupling of the sleeve bolt assembly portion and the sleeve holder receptacle portion. The first sealing element is configured to provide a substantially fluid impermeable seal between the elongate radiation transparent sleeve element and the sleeve holder receptacle portion.
Abstract translation: 公开了一种用于辐射源的套筒保持器组件。 套筒保持器组件包括：细长辐射透明套筒元件; 耦合到所述细长辐射透明套筒元件的套筒保持器插座部分; 联接到所述套筒保持器容置部分的套筒螺栓组件部分; 第一密封元件，设置在套筒保持器容置部分和套筒螺栓组件部分之间; 以及锁定元件，其构造成防止套筒螺栓组件部分和套筒保持器容置部分的分离。 第一密封元件构造成在细长辐射透明套筒元件和套筒保持器容置部分之间提供基本流体的不可渗透密封。
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公开(公告)号：US20130234037A1
公开(公告)日：2013-09-12
申请号：US13821786
申请日：2011-09-12
Applicant: Cristian Moglan , Christopher Sheculski
Inventor： Cristian Moglan , Christopher Sheculski
IPC: A61L2/10
CPC classification number: A61L2/10 , C02F1/325 , C02F2201/004 , C02F2201/3225 , C02F2303/14 , H01R13/625 , H01R33/76
Abstract: There is described a radiation source assembly comprising an elongate radiation source; a reactor port for receiving and reversibly securing the elongate radiation source; a top plug element for reversible connection to a proximal end of the radiation source and reversible engagement with the reactor port; the top plug element configured to be disengaged from reactor port without disengagement of the elongate radiation source from the reactor port.
Abstract translation: 描述了包括细长辐射源的辐射源组件; 用于接收和可逆地固定细长辐射源的反应器端口; 顶部插塞元件，用于与辐射源的近端可逆地连接并且与反应器端口可逆地接合; 所述顶塞元件构造成在不从所述反应器端口分离所述细长辐射源的情况下与反应器端口脱离接合。
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公开(公告)号：US20130022966A1
公开(公告)日：2013-01-24
申请号：US13399556
申请日：2012-02-17
Applicant: Spyros Stylianou
Inventor： Spyros Stylianou
CPC classification number: C07K14/43581 , A61K38/00 , C07K14/4702 , C07K2319/10
Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
Abstract translation: 本发明基于Notch信号传导途径与癌症相关的发现。 因此，本发明提供了治疗癌症的方法和组合物。 还提供了调节Notch信号传导途径中的蛋白质的表达和/或活性用于受试者的癌症诊断和治疗的方法。
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公开(公告)号：US20110256168A1
公开(公告)日：2011-10-20
申请号：US13168167
申请日：2011-06-24
Applicant: Andrea Crisanti
Inventor： Andrea Crisanti
IPC: A61K39/385 , A61P37/04 , C07K14/435 , C07K19/00 , C07K17/00 , A61K38/17
CPC classification number: C12N15/87 , A61K38/00 , A61K39/00 , A61K47/62 , A61K48/00 , C07K14/35 , C07K14/43581 , C07K2319/00
Abstract: The subject invention pertains to a conjugate comprising: (a) a first region comprising the homeodomain of antennapedia or a variant thereof; and (b) a second region not naturally associated with the first region. In one embodiment, the second region of the conjugate comprises a protein of at least 100 amino acids.
Abstract translation: 本发明涉及一种缀合物，其包含：（a）包含触角介体的同源结构域或其变体的第一区域; 和（b）不与第一区域天然相关联的第二区域。 在一个实施方案中，缀合物的第二区域包含至少100个氨基酸的蛋白质。
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