公开(公告)号：US06610036B2

公开(公告)日：2003-08-26

申请号：US09776782

申请日：2001-02-06

Applicant: John D. Branch ,  Steven R. Duhamel ,  Scott O. Ganaja

Inventor： John D. Branch ,  Steven R. Duhamel ,  Scott O. Ganaja

IPC: A61M3700

CPC classification number: B65D35/28

Abstract: An eye drop dispensing device includes a trough member with a space to receive a cartridge housing enclosing a collapsible bag containing an ophthalmic liquid and comprising a spring finger applying pressure to the bag. The bag includes a wall pierced by a needle coupling the liquid to pump means through a one-way valve. The pump means includes a plunger biased to a resting position establishing a dosage chamber. Actuator means moves the plunger to enlarge the dosage chamber, causing a drop in pressure which draws a predetermined quantity of the liquid through the one-way valve into the dosage chamber. The actuator means then releases the plunger so that it moves to compress the dosage chamber to pump the liquid in the dosage chamber through a second one-way valve to spray the liquid through pinholes formed in a nozzle angled to direct the liquid as eye drops to the user's eye.

公开(公告)号：US06599265B2

公开(公告)日：2003-07-29

申请号：US09897695

申请日：2001-07-02

Applicant: Edwin Bon

Inventor： Edwin Bon

IPC: A61M3700

CPC classification number: A61M25/0136

Abstract: A brake assembly for a steerable catheter that allows both dynamic locking and swapping between a locked mode of operation and an unlocked mode of operation is described. Dynamic locking enables fine adjustment of the catheter shaft position, while swapping between modes results in a more multipurpose catheter. Generally, the brake assembly includes a brake shoe positioned for slidable movement between a locked position contacting the steering dial and an unlocked position not contacting the steering dial. At least one spring biases the brake shoe toward the locked position. A catheter including a brake assembly is also described.

公开(公告)号：US06595941B1

公开(公告)日：2003-07-22

申请号：US09481283

申请日：2000-01-11

Applicant: Duane D. Blatter

Inventor： Duane D. Blatter

IPC: A61M3700

CPC classification number: A61M25/10 ,  A61M2025/1052

Abstract: Vascular access systems, devices and methods for facilitating repeated access to a blood vessel. These systems, devices and methods can be used in external blood treatment, such as dialysis, and in intra-venous administration of medicines, such as heparin, for extended periods of time, while avoiding deleterious effects such as those derived from repeated puncturing of the blood vessel tissues or exposure of such tissues to abnormal fluid flows. The vascular access systems comprise an anastomosis graft vessel, an occlusal device, such as an occlusal balloon, and a port device for accessing the occlusal device. Occlusal devices can be self-contained, they can rely on osmosis, and they can serve as the support of an agent to which the blood stream is exposed, either by transport or by mere contact. In addition, occlusal devices can adopt a distended and a collapsed configuration, the latter allowing for blood flow through the anastomosis graft vessel.

Abstract translation: 用于促进重复进入血管的血管通路系统，装置和方法。 这些系统，装置和方法可以用于外部血液处理，例如透析，以及在静脉内施用药物，例如肝素，延长的时间段，同时避免有害影响，例如衍生自反复穿刺 血管组织或这些组织暴露于异常流体流动。 血管通路系统包括吻合移植血管，咬合装置，例如咬合气囊，以及用于进入咬合装置的端口装置。 咬合装置可以是独立的，它们可以依靠渗透，并且可以通过运输或仅通过接触作为血液暴露于的药剂的支持。 此外，咬合装置可以采用扩张和收缩的构型，后者允许血液流过吻合移植血管。

公开(公告)号：US06585679B1

公开(公告)日：2003-07-01

申请号：US09425071

申请日：1999-10-21

Applicant: Paul Hallen

Inventor： Paul Hallen

IPC: A61M3700

CPC classification number: A61M3/0241 ,  A61M3/005 ,  A61M2210/0612

Abstract: A system and method are provided for oxygenating infusion/irrigation fluid, and for providing the hyperoxic infusion/irrigation fluid so formed to an ophthalmic surgical site.

Abstract translation: 提供了用于给输注/冲洗液充氧的系统和方法，并且用于将如此形成的高氧输注/冲洗流体提供给眼科手术部位。

公开(公告)号：US06575931B1

公开(公告)日：2003-06-10

申请号：US09562612

申请日：2000-05-01

Applicant: Dean M. Ponzi

Inventor： Dean M. Ponzi

IPC: A61M3700

CPC classification number: A61M25/008 ,  A61B18/1492 ,  A61B18/24 ,  A61M25/0069 ,  A61M25/0082 ,  A61M25/0084 ,  A61M25/0147 ,  A61M2025/0089 ,  A61M2025/0091 ,  A61M2025/0096 ,  A61M2025/015

Abstract: An injection catheter is provided. The catheter comprises a catheter body comprising a flexible tubing having proximal and distal ends and at least one lumen therethrough. The catheter further comprises a tip section comprising a flexible tubing having proximal and distal ends. The proximal end of the tip section is mounted at the distal end of the catheter body. A needle control handle is provided at the proximal end of the catheter body. An injection needle extends through the tip section, catheter body, and needle control handle and has a proximal end attached to the needle control handle and a distal end within the tip section. The injection needle is longitudinally slidable within the tip section so that its distal end can extend beyond the distal end of the tip section upon suitable manipulation of the needle control handle. The injection needle comprises one or more pieces of tubing, at least one of which comprises plastic.

Abstract translation: 提供了一种注射导管。 导管包括导管本体，该导管主体包括具有近端和远端以及穿过其中的至少一个腔的柔性管。 导管进一步包括尖端部分，其包括具有近端和远端的柔性管。 尖端部分的近端安装在导管主体的远端。 在导管主体的近端设有针控制手柄。 注射针穿过尖端部分，导管主体和针控制柄，并且具有附接到针控制手柄的近端和尖端部分内的远端。 注射针可以在尖端部分内纵向滑动，使得其适当地操纵针控制手柄时，其远端可以延伸超出尖端部分的远端。 注射针包括一个或多个管，其中至少一个包括塑料。

公开(公告)号：US06572585B2

公开(公告)日：2003-06-03

申请号：US09942473

申请日：2001-08-29

Applicant: Soo Bong Choi

Inventor： Soo Bong Choi

IPC: A61M3700

CPC classification number: A61M5/14244 ,  A61M5/14248 ,  A61M5/1456 ,  A61M2205/3306 ,  A61M2205/3365 ,  A61M2205/3523 ,  A61M2205/3553

Abstract: Disclosed is an automatic syringe device including a syringe pump having a housing defined therein with a syringe receiving chamber for receiving a syringe, a control unit received in the housing and adapted to control a motor adapted to supply, to the syringe pump, a drive force for injecting a liquid medicine out of the syringe, a transmitter/receiver unit received in the housing and electrically connected to the control unit, and a remote controller adapted to control the control unit via the transmitter/receiver unit. The remote controller includes a transmitter/receiver unit adapted to conduct transmission and reception of signals to and from the control unit of the syringe pump via the transmitter/receiver unit of the syringe pump, a control unit adapted to control the transmitter/receiver unit of the remote controller, and a display adapted to display an ON or OFF state.

Abstract translation: 公开了一种自动注射器装置，其包括注射器泵，其具有限定在其中的壳体，其具有用于接收注射器的注射器接收室，容纳在壳体中并适于控制适于向注射器泵提供驱动力的电动机的控制单元 用于将注射器内的液体药物注入到容纳在外壳中并电连接到控制单元的发射器/接收器单元和适于经由发射器/接收器单元控制控制单元的遥控器。 所述遥控器包括发射器/接收器单元，其适于经由所述注射器泵的发射器/接收器单元进行到所述注射器泵的控制单元的传送和接收信号，所述控制单元适于控制所述发射器/接收器单元 遥控器和适于显示ON或OFF状态的显示器。

公开(公告)号：US06572576B2

公开(公告)日：2003-06-03

申请号：US09900362

申请日：2001-07-07

Applicant: James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

Inventor： James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

IPC: A61M3700

CPC classification number: A61M1/3626 ,  A61M1/3656 ,  A61M2205/13

Abstract: One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known is the detection of infiltrated air in a blood line, but this only works in blood lines under negative pressure. According to the invention, a leak detector for return lines is provided by periodically generating a negative pressure, which may be brief or at a 50% duty cycle, in the blood return line to draw air into it and thereby reveal the leaks using an air sensor. Although the return line is ordinarily under positive pressure, during the negative pressure cycle, the blood return line draws air through any leaks or disconnects. If air is detected, the system is shut down and an alarm generated.

Abstract translation: 体外血液治疗如透析自动化中最重要的安全问题之一是出现血液渗漏的风险。 这样的系统以如此高的速度吸取血液，使得血液回路中完整性的丧失可能是灾难性的。 已知的最可靠的泄漏检测方法是检测血液中的渗透空气，但这仅在负压下的血液系统中起作用。 根据本发明，通过在血液回流管线周期性地产生负压（可以是短暂的或占空比为50％）来提供返回管线的泄漏检测器，以将空气吸入其中，从而利用空气泄露泄漏 传感器。 虽然返回线通常处于正压力下，但是在负压循环期间，血液回流管路通过任何泄漏或断开线吸入空气。 如果检测到空气，则系统关闭并产生报警。

公开(公告)号：US06569112B2

公开(公告)日：2003-05-27

申请号：US09888986

申请日：2001-06-26

Applicant: Meir Strahilevitz

Inventor： Meir Strahilevitz

IPC: A61M3700

CPC classification number: A61M1/3679 ,  A61M1/3475 ,  A61M1/3486

Abstract: Extracorporeal affinity adsorption treatments which are aimed at the substantial removal of two or more compounds that are etiological in the pathogenesis of diseases in man provide effective therapeutic intervention means for these diseases. The methods are particularly suitable for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases. Extracorporeal chelation and immunotherapy for atherosclerosis, extracorporeal chelation treatment with on-line regeneration or replacement of chelant, extracorporeal immunotherapy with antibody fragments, and extracorporeal immunoadsorption utilizing antibodies bound to Protein A are also disclosed.

公开(公告)号：US06565532B1

公开(公告)日：2003-05-20

申请号：US09614321

申请日：2000-07-12

Applicant: Vadim Vladimirovich Yuzhakov ,  Vladimir Gartstein ,  Grover David Owens

Inventor： Vadim Vladimirovich Yuzhakov ,  Vladimir Gartstein ,  Grover David Owens

IPC: A61M3700

CPC classification number: B81C99/0085 ,  A45D34/04 ,  A45D2200/1018 ,  A45D2200/1045 ,  A61M37/0015 ,  A61M37/0076 ,  A61M2037/003 ,  A61M2037/0053 ,  A61N1/30 ,  B29C51/00 ,  B81B2201/055

Abstract: An array of microneedles is provided to apply semi-permanent or permanent markings to skin, or to apply semi-permanent subcutaneous makeup or other cosmetic compounds to skin. The microneedles can apply identifications or other tattoo-like graphics, and will not enter into the dermal layer of the skin so that the application procedure is painless. The microneedle array is also useful for delivering specific compounds or actives into the skin, such as cosmetic compounds or nutrients, or various skin structure modifiers that can be delivered subcutaneously without having to visit a cosmetic surgery clinic.

Abstract translation: 提供一系列微针，以将半永久性或永久性标记施用于皮肤，或将半永久性皮下化妆或其他化妆品化合物施用于皮肤。 微针可以应用标识或其他纹身图形，并且不会进入皮肤的真皮层，使得应用程序是无痛的。 微针阵列还可用于将特定的化合物或活性物质递送到皮肤中，例如化妆品化合物或营养物，或可以皮下递送而不必访问整容手术诊所的各种皮肤结构修饰剂。

公开(公告)号：US06558352B1

公开(公告)日：2003-05-06

申请号：US09580080

申请日：2000-05-30

Applicant: Thomas Hogan

Inventor： Thomas Hogan

IPC: A61M3700

CPC classification number: A61D7/00

Abstract: A system and method for automatically controlling the quantitative delivery of, and then recording the occurrence of the administration of medicines to animals is disclosed and claimed. An intelligent syringe receives and automatically implements an instruction relating to a preferred quantity of medicine to be delivered to a specific animal, based on the measured weight of the animal. Upon actuation of the intelligent syringe, a first signal containing information relating to the actuation of the intelligent syringe, and the resulting injection of the animal is transmitted to a data repository. An EID is attached to the animal to provide a tamper-resistant electronic identification of the animal, and a receiver is utilized for receiving the first signal from the intelligent syringe and the electronic identification of the animal. Thereafter, a computer database maintains the information contained in the first signal for selective access and analysis.

Abstract translation: 公开并要求保护自动控制向动物施用药物的定量递送，然后记录给药的系统和方法。 智能注射器基于动物的测量重量，接收并自动实施与要运送给特定动物的优选药量相关的指令。 在启动智能注射器时，将包含与智能注射器的致动有关的信息的第一信号和由此引起的动物的信息传送到数据存储库.EID附接到动物以提供防篡改的电子识别 并且使用接收器来接收来自智能注射器的第一信号和动物的电子识别。 此后，计算机数据库维护包含在第一信号中的信息用于选择性访问和分析。