公开(公告)号：US09273087B2

公开(公告)日：2016-03-01

申请号：US14599787

申请日：2015-01-19

Applicant: PRIME SYNTHESIS, INC.

Inventor： Marc L. Rothstein ,  Dianne M. Rothstein ,  Dan P. Lee

IPC: C07H21/00 ,  C03C17/32 ,  C03C11/00 ,  G01N33/543 ,  G01N33/552

CPC classification number: C07H21/00 ,  C03C11/00 ,  C03C17/32 ,  C03C17/328 ,  G01N33/54313 ,  G01N33/54353 ,  G01N33/552 ,  Y10T428/2989 ,  Y10T428/2996 ,  Y10T428/2998

Abstract: A method for preparing a crosslinked polymer coated controlled porosity glass (CPG) particle is provided. The method involves mixing CPG particles in a solution comprising polyvinylbenzylchloride and a first solvent at a temperature below 10° C. A second solvent is added and a crosslinking agent is added to the mixture. The first solvent is removed rapidly within 1½ hours of addition of the crosslinking agent. The crosslinking reaction is permitted to proceed and the mixture is then cooled and treated to remove any remaining solvent. The resulting coated CPG particles are washed and dried. Also provided a polymer coated CPG particles using for loading ligand thereon.

Abstract translation: 提供了一种制备交联聚合物涂层控制孔隙玻璃（CPG）颗粒的方法。 该方法包括在低于10℃的温度下将CPG颗粒混合在包含聚乙烯基苄基氯和第一溶剂的溶液中。加入第二溶剂并向混合物中加入交联剂。 第一溶剂在加入交联剂的1小时内迅速除去。 允许交联反应进行，然后将混合物冷却并处理以除去任何残留的溶剂。 将所得涂覆的CPG颗粒洗涤并干燥。 还提供了用于在其上负载配体的聚合物涂覆的CPG颗粒。

公开(公告)号：US07803209B2

公开(公告)日：2010-09-28

申请号：US11719967

申请日：2005-09-30

Applicant: Hideyuki Takahashi

Inventor： Hideyuki Takahashi

IPC: B22F3/00 ,  C23C14/34

CPC classification number: C22C12/00 ,  B22F2003/247 ,  B22F2998/10 ,  B22F2999/00 ,  C22C28/00 ,  C23C14/3414 ,  G11B7/266 ,  B22F9/082 ,  B22F3/10 ,  B22F3/24 ,  B22F2201/11

Abstract: Provided is an Sb—Te alloy sintered compact sputtering target having at least Sb or Te as its primary component, wherein surface roughness Ra is 0.4 μm or less, purity excluding gas components is 4N or more, content of gas components as impurities is 1500 ppm or less, and average crystal grain size is 50 μm or less. With this Sb—Te alloy sintered compact sputtering target, the density of defects having a maximum length of 10 μm or greater arising in a surface finish by machining is 80 or less in an 800 μm square. Thus, the Sb—Te alloy sputtering target structure can be uniformalized and refined, generation of cracks in the sintered target can be inhibited, and generation of arcing during sputtering can be inhibited. Further, surface ruggedness caused by sputter erosion can be reduced in order to obtain a high quality Sb—Te alloy sputtering target.

Abstract translation: 提供一种Sb-Te合金烧结体型溅射靶，其至少具有Sb或Te作为其主要成分，其中表面粗糙度Ra为0.4μm以下，除气体成分以外的纯度为4N以上，作为杂质的气体成分的含量为1500ppm 以下，平均结晶粒径为50μm以下。 对于该Sb-Te合金烧结体型溅射靶，通过机械加工得到的表面光洁度中产生的最大长度为10μm以上的缺陷密度为800μm以下，为80以下。 因此，Sb-Te合金溅射靶结构可以均匀化和精制，可以抑制烧结靶中的裂纹的产生，并且可以抑制溅射期间的电弧放电。 此外，为了获得高品质的Sb-Te合金溅射靶，可以减少由溅射侵蚀引起的表面粗糙度。

公开(公告)号：US07176293B1

公开(公告)日：2007-02-13

申请号：US10048046

申请日：2000-06-14

Applicant: Thanos Halazonetis ,  Daniel Scolnick

Inventor： Thanos Halazonetis ,  Daniel Scolnick

IPC: C07H21/02

CPC classification number: C07K14/4702

Abstract: An isolated nucleic acid sequence of a mitotic checkpoint gene, chfr, encodes a Chfr protein having a Forkhead-associated domain and a Ring Finger. This protein is required for regulation of the transition of cells from prophase to metaphase during mitosis. The chfr nucleic acid and Chfr polypeptide are useful in diagnosing tumorigenic cells and in screening for drugs which can inhibit the activity of Chfr in a cancer cell, thereby rendering the cell more sensitive to additional anti-tumor therapies.

Abstract translation: 有丝分裂检查点基因chfr的分离核酸序列编码具有叉头相关结构域和环指的Chfr蛋白。 这种蛋白质是调控有丝分裂期间细胞从前期转变为中期所必需的。 chfr核酸和Chfr多肽可用于诊断致瘤细胞和筛选可抑制癌细胞中Chfr活性的药物，从而使细胞对其他抗肿瘤治疗更敏感。

公开(公告)号：USD533379S1

公开(公告)日：2006-12-12

申请号：US29243143

申请日：2005-11-18

Applicant: Frans Lennart Axhamre

Designer： Frans Lennart Axhamre

公开(公告)号：US07138040B2

公开(公告)日：2006-11-21

申请号：US10362152

申请日：2002-07-11

Applicant: Takeo Okabe ,  Akihiro Aiba ,  Junnosuke Sekiguchi ,  Hirohito Miyashita ,  Ichiroh Sawamura

Inventor： Takeo Okabe ,  Akihiro Aiba ,  Junnosuke Sekiguchi ,  Hirohito Miyashita ,  Ichiroh Sawamura

IPC: C25B11/04 ,  C25D3/38

CPC classification number: C25D7/12 ,  C25D17/10

Abstract: An electrolytic copper plating method characterized in employing phosphorous copper as the anode upon performing electrolytic copper plating, and performing electrolytic copper plating upon making the crystal grain size of the phosphorous copper anode 10 to 1500 μm when the anode current density during electrolysis is 3 A/dm2 or more, and making the grain size of the phosphorous copper anode 5 to 1500 μm when the anode current density during electrolysis is less than 3 A/dm2. The electrolytic copper plating method and phosphorous copper anode used in such electrolytic copper plating method is capable of suppressing the generation of particles such as sludge produced on the anode side within the plating bath, and is capable of preventing the adhesion of particles to a semiconductor wafer. A semiconductor wafer plated with the foregoing method and anode having low particle adhesion are provided.

Abstract translation: 一种电解铜电镀方法，其特征在于在进行电解铜电镀时使用磷铜作为阳极，并且当电解时的阳极电流密度为3A / cm 3时，使磷铜阳极的晶粒尺寸为10〜1500μm，进行电解镀铜， dm 2以上，并且当电解中的阳极电流密度小于3A / dm 2时，使磷铜阳极的晶粒尺寸为5〜1500μm。 在这种电解镀铜方法中使用的电解铜电镀方法和磷铜阳极能够抑制电镀槽内阳极侧产生的污泥等颗粒的产生，能够防止颗粒附着在半导体晶片上 。 提供了镀上述方法的半导体晶片和具有低颗粒附着力的阳极。

公开(公告)号：US07137756B1

公开(公告)日：2006-11-21

申请号：US11261224

申请日：2005-10-27

Applicant: William D. Jones

Inventor： William D. Jones

IPC: E01F5/00

CPC classification number: E01F5/005

Abstract: A box culvert and gasket assembly is provided that enables fluid-tight bell-and spigot joints to be formed between abutting ends of box culverts. The joints according to the assembly of the present invention can remain fluid-tight up to at least 13 psi of water pressure. The gasket is preferably a one-piece, endless rubber gasket that is applied over the end of a spigot that is rectangular in end elevation. The corners of the rectangular spigot are rounded to enable the gasket to extend continuously over the corner without the need for 45° cuts and splices. Preferably, the gasket is made from a single elongate gasket piece that is cut to size and that has ends that are bonded together via a butt vulcanization technique. A storm drain and sewer assembly and a method of forming a fluid-tight bell-and spigot joint are also provided.

Abstract translation: 提供了一种箱涵和垫圈组件，其能够在盒式涵洞的邻接端之间形成流体密封的钟形和插口接头。 根据本发明的组件的接头可以保持流体密封至多至少13psi的水压。 衬垫优选是一体的环形橡胶衬垫，其被施加在端部立方体上的插口的端部上。 矩形插口的角部是圆形的，以使垫片能够在角落上连续延伸，而不需要45°切割和拼接。 优选地，衬垫由单个细长的衬垫片制成，其被切割成尺寸，并且具有通过对接硫化技术结合在一起的端部。 还提供了一种风雨排水和下水道组件以及形成流体密封的钟形和插口接头的方法。

公开(公告)号：US07135094B2

公开(公告)日：2006-11-14

申请号：US10610180

申请日：2003-06-30

Applicant: Kazumasa Watanabe ,  Hirokuni Ohno

Inventor： Kazumasa Watanabe ,  Hirokuni Ohno

IPC: D21F7/08 ,  D21F7/12 ,  B32B3/02 ,  B32B5/06

CPC classification number: D21F7/10 ,  D21F7/083 ,  Y10S162/90 ,  Y10S162/904 ,  Y10T428/192 ,  Y10T428/198 ,  Y10T442/3041 ,  Y10T442/3724

Abstract: An endless papermaking press felt comprises a base and a batt layer intertwiningly integrated with the base. The batt layer comprises a wet paper web side layer and a machine side layer formed on an outer surface and inner surface of a base respectively, The base is manufactured from belt-shaped partial base bodies, which are connected to one another in side-by-side relationship. The press felt can be manufactured easily and at reduced cost.

Abstract translation: 环形造纸压榨毛毯包括基部和与基部交织成一体的絮垫层。 絮垫层包括分别形成在基底的外表面和内表面上的湿纸幅侧层和机器侧层。基底由带状部分基体制成，它们彼此相连，并排连接 边缘关系 压榨毛毡可以容易地并且以较低的成本制造。

公开(公告)号：US07105345B2

公开(公告)日：2006-09-12

申请号：US10696282

申请日：2003-10-29

Applicant: James M. Wilson ,  Weidong Xiao

Inventor： James M. Wilson ,  Weidong Xiao

IPC: C12N5/10 ,  C12N15/864 ,  C07H21/04

CPC classification number: C12N15/86 ,  A61K48/00 ,  C07K14/005 ,  C07K14/505 ,  C07K14/8125 ,  C12N7/00 ,  C12N2750/14042 ,  C12N2750/14121 ,  C12N2750/14122 ,  C12N2750/14143 ,  C12N2799/025

Abstract: The nucleic acid sequences of adeno-associated virus (AAV) serotype 1 are provided, as are vectors and host cells containing these sequences and functional fragments thereof. Also provided are methods of delivering genes via AAV-1 derived vectors.

Abstract translation: 提供腺相关病毒（AAV）血清型1的核酸序列，载体和含有这些序列及其功能片段的宿主细胞也是如此。 还提供了通过AAV-1衍生的载体递送基因的方法。

公开(公告)号：US07093825B2

公开(公告)日：2006-08-22

申请号：US10406674

申请日：2003-04-03

Applicant: Osamu Kawamura ,  Masao Nakazawa

Inventor： Osamu Kawamura ,  Masao Nakazawa

IPC: E04F11/18

CPC classification number: E04F11/1863 ,  E04F2011/1885

Abstract: A handrail for preventing dangers during walking and movements to standing or sitting positions, for correcting postures, and for simplifying walking movements of physically handicapped persons, persons with weak grip strength, and persons of low functional capacity caused by collagenosis or rheumatism. The handrail is an elongate handrail having a smooth curved line periphery. The pinky-engaging side of the handrail is protuberated in a circular shape and has a recess at a portion thereof where a fingertip of a person grasping the handrail engages a lower end vicinity position of the circular shape.

公开(公告)号：US07083348B2

公开(公告)日：2006-08-01

申请号：US10994504

申请日：2004-11-22

Applicant: Kazuya Watanabe ,  Hiroshi Kozaki ,  Keisuke Fujii ,  Keiichiro Minegishi

Inventor： Kazuya Watanabe ,  Hiroshi Kozaki ,  Keisuke Fujii ,  Keiichiro Minegishi

IPC: B05C1/00 ,  B43K29/00

CPC classification number: B43K29/00 ,  B65H37/007

Abstract: In a combination coating film transfer tool and writing implement, a reversible coating film transfer tool can be fitted to the writing implement in either of two ways: one in which the coating film extending past the transfer head is exposed for use, and the other in which the coating film is protected within a housing formed on the writing implement.

Abstract translation: 在组合涂膜转移工具和书写工具中，可以以两种方式将可逆涂膜转​​移工具安装到书写工具：其中延伸通过转印头的涂膜暴露于使用中，另一种在 涂层膜在形成在书写工具上的壳体内被保护。