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公开(公告)号：US20120220744A1
公开(公告)日：2012-08-30
申请号：US13404037
申请日：2012-02-24
Applicant: Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
Inventor： Yuwen Liu , Charlie Chen , Charles A. Francis , Junhao Ge , Yuan Xu , Li Yao , Arthur Back , Ying Zheng
IPC: C08F230/08
Abstract: Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
Abstract translation: 描述了眼科可接受的可湿性硅氧水凝胶隐形眼镜。 透镜衍生自包含第一硅氧烷单体的可聚合组合物。 当完全水合时，镜片具有眼科可接受的可润湿透镜表面。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。
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公开(公告)号：US20120220689A1
公开(公告)日：2012-08-30
申请号：US13404035
申请日：2012-02-24
Applicant: Li Yao , Ye Hong , Yuwen Liu , Charlie Chen , Charles A. Francis , Arthur Back
Inventor： Li Yao , Ye Hong , Yuwen Liu , Charlie Chen , Charles A. Francis , Arthur Back
CPC classification number: G02B1/043 , C08L83/12 , C08L101/14 , C08L33/10 , C08L33/08
Abstract: Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono-functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate-containing siloxane monomer of at least 30:1, respectively.
Abstract translation: 由可聚合组合物的反应产物形成具有良好的尺寸稳定性的眼科学可接受的硅酮水凝胶隐形眼镜，并且可以制造不含醇溶剂的可聚合组合物，该可聚合组合物包含至少一种含单分子丙烯酸酯的含有单官能丙烯酸酯的硅氧烷单体 重量小于2000; 至少一种分子量至少为3,000的含二官能丙烯酸酯的硅氧烷单体; 和至少一种亲水性含乙烯基单体，其中所述可聚合组合物的含单体官能丙烯酸酯的硅氧烷单体的总量与含二官能丙烯酸酯的硅氧烷单体的总量的摩尔比分别为至少30:1 。
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公开(公告)号：US20120216488A1
公开(公告)日：2012-08-30
申请号：US13404027
申请日：2012-02-24
Applicant: Yuwen Liu , Charlie Chen , Ye Hong , Charles A. Francis , Li Yao , Arthur Back
Inventor： Yuwen Liu , Charlie Chen , Ye Hong , Charles A. Francis , Li Yao , Arthur Back
CPC classification number: G02B1/043 , B65B55/02 , C08L101/14 , C08L83/04 , C08L51/085
Abstract: Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces. The hydrated silicone hydrogel contact lenses have diameters that are at least 24% larger than the diameters of the silicone hydrogel contact lenses prior to hydration or washing.
Abstract translation: 制造硅氧烷水凝胶隐形眼镜，而不使用挥发性有机溶剂从聚合的隐形眼镜体提取物质，而是用含水液体洗涤。 如此生产的硅酮水凝胶隐形眼镜具有眼睛可润湿的透镜表面。 水合硅酮水凝胶隐形眼镜的直径比水合或洗涤前的硅酮水凝胶隐形眼镜的直径大至少24％。
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44.发明申请Contact Lens Sets And Methods To Prevent Or Slow Progression Of Myopia Or Hyperopia 有权隐形眼镜套和方法来预防或缓慢进展近视或远视公开(公告)号：US20120194780A1
公开(公告)日：2012-08-02
申请号：US13318630
申请日：2010-05-03
Applicant: Arthur Back
Inventor： Arthur Back
IPC: G02C7/04
CPC classification number: G02C7/041 , G02C7/042 , G02C2202/24
Abstract: Methods for slowing progression of myopia or hyperopia of human patients include a step of providing contact lenses. The contact lenses have two or more refractive powers. A first refractive power provides clear visual acuity and a second refractive power provides a defocused retinal image to the human patient. The methods involve providing first and second sets of the contact lenses, the contact lenses of the second set have a different optical design than the contact lenses of the first set. With the present methods, an eye care practitioner is able to select one or more contact lenses from the second set of contact lenses based on one or more ocular parameters of the patient, one or more responses of the patient to the contact lens of the first set, or both, to provide an improved clinical benefit to the patient compared to the benefit provided by the first set of contact lenses.
Abstract translation: 减慢人类近视或远视进展的方法包括提供隐形眼镜的步骤。 隐形眼镜具有两个或更多个屈光力。 第一屈光力提供清晰的视力，第二屈光力提供了散焦视网膜图像给人类患者。 所述方法包括提供第一组和第二组隐形眼镜，第二组的隐形眼镜具有与第一组的隐形眼镜不同的光学设计。 根据本方法，眼科医生能够基于患者的一个或多个眼部参数从第二组隐形眼镜中选择一个或多个隐形眼镜，患者对第一个隐形眼镜的隐形眼镜的一个或多个响应 设置或两者，以与第一组隐形眼镜提供的益处相比，为患者提供改善的临床益处。
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45.发明授权Contact lenses and methods for reducing conjunctival pressure in contact lens wearers 有权接触镜和减少隐形眼镜佩戴者结膜压力的方法公开(公告)号：US07360890B2
公开(公告)日：2008-04-22
申请号：US11500178
申请日：2006-08-07
Applicant: Arthur Back
Inventor： Arthur Back
IPC: G02C7/04
Abstract: Contact lenses, such as silicone hydrogel contact lenses, which are effective in reducing conjunctival pressure, and conjunctival epithelial flap formation or occurrence of a lens wearer's eye, and methods of reducing conjunctival pressure by a contact lens and/or formation of conjunctival epithelial flap formation are described. The present contact lenses reduce the interaction and/or pressure of the contact lens, or portion thereof, with or on the conjunctiva of a lens wearer's eye.
Abstract translation: 有效降低结膜压力的结晶上皮瓣形成或镜片佩戴者眼睛发生的隐形眼镜，例如硅酮水凝胶隐形眼镜，以及通过隐形眼镜降低结膜压力和/或形成结膜上皮瓣形成的方法 被描述。 本隐形眼镜减少隐形眼镜或其部分与透镜佩戴者的眼睛或结膜上的相互作用和/或压力。
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Patent Agency Ranking
公开(公告)号：US20060203189A1
公开(公告)日：2006-09-14
申请号：US11421225
申请日：2006-05-31
Applicant: Arthur Ho , Arthur Back
Inventor： Arthur Ho , Arthur Back
IPC: G02C7/04
CPC classification number: G02C7/048 , B29D11/00432 , G02C7/028 , G02C7/04 , G02C7/043 , G02C2202/22
Abstract: Methods for producing a junctionless ophthalmic lens are provided. Additionally, ophthalmic lenses having junctionless, three dimensional surfaces, for example, asymmetrical anterior and/or posterior surfaces, as well as molding tools used in the production of such lenses, are also provided. The method generally include providing sample data points to define a surface contour, and interpolating between these data points using an algorithm to produce a simulated three dimensional surface. The simulated three dimensional surface is used in producing an ophthalmic lens, for example, in cast molding a contact lens.
Abstract translation: 提供无连接眼科镜片的制造方法。 此外，还提供了具有无连接的三维表面，例如不对称的前表面和/或后表面的眼镜片，以及用于制造这种镜片的成型工具。 该方法通常包括提供样本数据点以定义表面轮廓，并且使用算法在这些数据点之间内插以产生模拟的三维表面。 模拟的三维表面用于制造眼科镜片，例如在模制成型的隐形眼镜中。
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公开(公告)号：US07026353B2
公开(公告)日：2006-04-11
申请号：US10434193
申请日：2003-05-09
Applicant: Staffan Kjelleberg , Peter David Steinberg , Carola Holmstrom , Arthur Back
Inventor： Staffan Kjelleberg , Peter David Steinberg , Carola Holmstrom , Arthur Back
CPC classification number: A61K31/365 , A01N43/08 , A61K2300/00
Abstract: A method of inhibiting the growth of a Gram positive bacterium, the method comprising treating the bacterium with an effective amount of one or more furanones having the Formula as set out in the Figure, wherein the effective amount of the one or more furanones does not substantially adversely effect the survival of an animal cell when exposed to the one or more furanones
Abstract translation: 一种抑制革兰氏阳性细菌生长的方法，所述方法包括用有效量的一种或多种如图所示的式的呋喃酮处理细菌，其中一种或多种呋喃酮的有效量基本上不 当暴露于一种或多种呋喃酮时，不利地影响动物细胞的存活
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公开(公告)号：US09296159B2
公开(公告)日：2016-03-29
申请号：US13983306
申请日：2012-02-23
Applicant: Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
Inventor： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
IPC: G02B1/04 , B29D11/00 , C08F290/06
CPC classification number: B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
Abstract: Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
Abstract translation: 衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在 在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于 可聚合组合物的含量为1〜20单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。
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49.发明授权Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses 有权硅酮水凝胶隐形眼镜和制造硅酮水凝胶隐形眼镜的方法公开(公告)号：US08672475B2
公开(公告)日：2014-03-18
申请号：US12894941
申请日：2010-09-30
Applicant: Yuwen Liu , Yuan Ji , David Morsley , Charles Francis , Arthur Back
Inventor： Yuwen Liu , Yuan Ji , David Morsley , Charles Francis , Arthur Back
CPC classification number: G02C7/049 , B29D11/00038 , B29D11/00067 , B29D11/00346 , G02B1/043 , C08L51/085 , C08L83/04
Abstract: Silicone hydrogel contact lenses, when hydrated, have a plurality of depressions on one or more of the lens surfaces. The depressions have a depth less than 1 micrometer, or less than 100 nanometers. The silicone hydrogel contact lenses have not been subject to treatment with plasma. Methods of manufacturing the silicone hydrogel contact lenses are also disclosed.
Abstract translation: 硅胶水凝胶隐形眼镜在水合时在一个或多个透镜表面上具有多个凹陷。 凹陷的深度小于1微米，或小于100纳米。 硅酮水凝胶隐形眼镜尚未经过等离子体治疗。 还公开了制造硅酮水凝胶隐形眼镜的方法。
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公开(公告)号：US20140009735A1
公开(公告)日：2014-01-09
申请号：US13983306
申请日：2012-02-23
Applicant: Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
Inventor： Ying Zheng , Yuan Xu , Junhao Ge , Charles A. Francis , Yuan Sun , Yuwen Liu , Charlie Chen , Ye Hong , Hongjin Qiu , Li Yao , Arthur Back
CPC classification number: B29D11/00125 , B29D11/0025 , C08F290/068 , G02B1/043 , C08L83/04 , C08L101/14
Abstract: Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.
Abstract translation: 衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在 在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于 可聚合组合物的含量为1〜20单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。
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