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77 条记录 (耗时 0.04 秒)

    Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
    43.
    发明授权
    Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine 有权
    杂环化合物，它们的制备，含有它们的药物组合物及其在医药中的用途

    公开(公告)号：US08110598B2

    公开(公告)日：2012-02-07

    申请号：US12018555

    申请日：2008-01-23

    申请人： Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Vijay Kumar Gajubhai Barot

    发明人： Braj Bhushan Lohray ,  Vidya Bhushan Lohray ,  Vijay Kumar Gajubhai Barot

    IPC分类号： A61K31/40 ,  C07D295/02 ,  C07D207/30

    CPC分类号： C07D207/325 ,  C07D207/33 ,  C07D207/333 ,  C07D207/335 ,  C07D207/36 ,  C07D207/48 ,  C07D401/04 ,  C07D405/04 ,  C07D409/04 ,  G06F3/14 ,  G06F3/1438 ,  G09G5/363 ,  G09G2360/122

    摘要： The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel substituted pyrrole compounds of the general formula (I), their analogs, their derivatives, their polymorphs, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and their pharmaceutical compositions containing them. This invention also relates to the process for preparing such compounds, a composition containing such a compound and the use of such a compound and composition in medicine.

    摘要翻译： 本发明涉及新的取代吡咯化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和含有它们的药学上可接受的组合物。 本发明特别涉及通式（I）的新型取代吡咯化合物，其类似物，其衍生物，其多晶型物，其互变异构形式，其药学上可接受的盐，其药学上可接受的溶剂合物及其含有它们的药物组合物。 本发明还涉及制备这种化合物的方法，含有这种化合物的组合物以及这种化合物和组合物在医药中的用途。

    Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
    50.
    发明授权
    Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them 失效
    单环化合物及其在药物中的应用：其制备方法和含有它们的药物组合物

    公开(公告)号：US07053217B2

    公开(公告)日：2006-05-30

    申请号：US10041384

    申请日：2002-01-08

    申请人： Ranga Madhavan Gurram ,  Venkateswarlu Akella ,  Rajagopalan Ramanujam ,  Ranjan Chakrabarti ,  Parimal Misra ,  Vidya Bhushan Lohray ,  Braj Bhushan Lohray ,  Rao Bheema Paraselli

    发明人： Ranga Madhavan Gurram ,  Venkateswarlu Akella ,  Rajagopalan Ramanujam ,  Ranjan Chakrabarti ,  Parimal Misra ,  Vidya Bhushan Lohray ,  Braj Bhushan Lohray ,  Rao Bheema Paraselli

    IPC分类号： C07D239/22

    CPC分类号： C07D239/36 ,  C07C217/22 ,  C07C237/32 ,  C07C247/04 ,  C07D239/90

    摘要： The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their analogs, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to novel intermediates, processes for their preparation and their use in the preparation of compounds of formula (I).

    摘要翻译： 本发明涉及新型抗肥胖和低胆固醇血症化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。 更具体地，本发明涉及通式（I）的新型β-芳基-α-氧代取代的烷基羧酸，其衍生物，它们的类似物，其互变异构形式，它们的立体异构体，它们的多晶型物，其药学上可接受的盐，它们的药学上可接受的 溶剂合物和含有它们的药学上可接受的组合物。 本发明还涉及制备上述新化合物，其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的溶剂化物和含有它们的药物组合物的方法。 本发明还涉及新型中间体，其制备方法及其在制备式（I）化合物中的用途。