公开(公告)号：US20190124948A1

公开(公告)日：2019-05-02

申请号：US16161266

申请日：2018-10-16

Applicant: Erber Aktiengesellschaft

Inventor： Sebastian FRUHAUF ,  Michaela THAMHESL ,  Martin PFEFFER ,  Dieter MOLL ,  Gerd SCHATZMAYR ,  Eva Maria BINDER

IPC: A23K10/14 ,  C12N9/18 ,  A23K50/80 ,  A23K50/30 ,  A23K50/75 ,  A23L3/3571 ,  C12N9/14

Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.

公开(公告)号：US10264807B2

公开(公告)日：2019-04-23

申请号：US15553218

申请日：2015-02-24

Applicant: ERBER AKTIENGESELLSCHAFT

Inventor： Markus Aleschko ,  Corinna Kern ,  Dieter Moll ,  Eva Maria Binder ,  Gerd Schatzmayr

IPC: C12N9/18 ,  C12N15/55 ,  A23K10/14 ,  A23K50/30 ,  A23K50/60 ,  A23K20/147 ,  C12N1/21

Abstract: The invention relates to fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to a fusarium toxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least one fusarium toxin.

公开(公告)号：US10149489B2

公开(公告)日：2018-12-11

申请号：US14914671

申请日：2014-08-27

Applicant: Erber Aktiengesellschaft

Inventor： Sebastian Fruhauf ,  Michaela Thamhesl ,  Martin Pfeffer ,  Dieter Moll ,  Gerd Schatzmayr ,  Eva Maria Binder

IPC: A23K10/14 ,  A23K50/80 ,  A23K50/75 ,  A23K50/30 ,  C12N9/18 ,  A23L3/3571 ,  C12N9/14

Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.

公开(公告)号：US20170099862A1

公开(公告)日：2017-04-13

申请号：US15316908

申请日：2015-06-03

Applicant: ERBER AKTIENGESELLSCHAFT

Inventor： Eva-Maria BINDER ,  Barbara CVAK ,  Alois SCHIESSL ,  Georg HÄUBL

IPC: A23L5/20 ,  G01N33/02

CPC classification number: A23L5/23 ,  A23L5/20 ,  A23V2002/00 ,  G01N1/4055 ,  G01N33/02 ,  G01N33/025 ,  G01N2001/4061

Abstract: In a method for extracting contaminants from agrarian products or foods or animal feeds containing agrarian products, comprising contacting a solvent for the contaminants with the agrarian products containing or having adsorbed the contaminants, or the foods or animal feeds, and at least one extraction buffer in an optionally closable mixing vessel, the extraction buffer, which is contained in a film soluble in the solvent and is supplemented with at least one surfactant, in particular nonionic surfactant, and the contaminated agrarian product or food or animal feed are contacted with cold water as solvent in the mixing vessel, and the extraction buffer and the contaminants are brought into solution by agitating or stirring in the mixing vessel; and apparatus therefor.

公开(公告)号：US20150274775A1

公开(公告)日：2015-10-01

申请号：US14434219

申请日：2013-10-04

Applicant: ERBER AKTIENGESELLSCHAFT

Inventor： Gerd Schatzmayr ,  Eva-Maria Binder ,  Michaela Thamhesl ,  Dieter Moll

IPC: C07K5/083 ,  C12N9/14

CPC classification number: C07K5/0806 ,  A23K10/14 ,  C12N9/14 ,  C12N9/52 ,  C12P17/183 ,  Y02P20/52

Abstract: Enzymes for transforming, in particular hydrolytically cleaving, ergopeptines, which ergopeptines are α/β-hydrolases hydrolytically cleaving ergopeptines in the cyclol ring, for the transformation of ergopeptines, and method for producing ergopeptine-metabolizing enzymes.

Abstract translation: 用于转化的酶，特别是水解切割的麦角霉素，其中孕激素是α环糊精水解酶在环环中水解切割ergopeptine，用于转化ergopeptine，以及用于生产ergopeptine代谢酶的方法。