Abstract:
In a document analysis system that receives and processes jobs from a plurality of users, in which each job may contain multiple electronic documents, to extract data from the electronic documents, a method of automatically extracting data from each received electronic document using a plurality of character recognition engines is provided. The method includes: automatically processing each received electronic document page using each of a plurality of recognition engines to extract data; comparing quality of data extracted from each of the recognition engines to assign a confidence score to the extracted data; and selecting extracted data having highest confidence score as the correct extracted data.
Abstract:
A composition having clevidipine as an active ingredient is described. The composition includes clevidipine as an active ingredient and an amount of the impurity H168/79 that is no greater than about 1.5%, or where the ratio between clevidipine and H168/79 is equal or above 60 to 1.
Abstract:
Pharmaceutical compositions, and a method of stabilizing pharmaceutical compositions having clevidipine, or any pharmaceutically acceptable salt thereof, as the active ingredient is described. The method includes the slowing down or inhibiting of the oxidation pathway of clevidipine. This can be accomplished by reducing the amount the pharmaceutical composition is exposed to oxygen and/or light during the manufacturing and storing processes. According to this method, oxygen must be removed or replaced, or light must be sufficiently blocked such that light energy cannot reach the active ingredient of the composition, or is reduced to a level that the light-induced oxidation reaction converting clevidipine to H324/78 is minimized, such that the total detectable level of H324/78 in a given composition sample does not exceed about 0.2% on a weight-by-weight basis, or the ratio of clevidipine to H324/78 is equal to or greater than about 450 to 1 on a weight-to-weight basis.
Abstract:
Pharmaceutical batch(es) or pharmaceutical formulation(s) comprising bivalirudin as the active ingredient, and a method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s). The pharmaceutical batch(es) or pharmaceutical formulation(s) may have a maximum impurity level of Asp9-bivalirudin that does not exceed about 0.6%. Also, the pharmaceutical batch(es) or pharmaceutical formulation(s) may have a reconstitution time that does not exceed about 42 seconds. The method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s) may comprise dissolving bivalirudin in a solvent to form a first solution, efficiently mixing a pH-adjusting solution with the first solution to form a second solution in which the pH-adjusting solution may comprise a pH-adjusting solution solvent, and removing the solvent and the pH-adjusting solution solvent from the second solution.
Abstract:
The present invention provides formulations useful for treating infections, in particular, formulations that include the active pharmaceutical ingredient Posaconazole in an injectable suspension of particles that is stable when subjected to terminal sterilization. Preferred median particle sizes of between 1.5 and 3.0 microns are found to result in superior pharmacokinetic characteristics-displayed in FIG. 7.
Abstract:
Pharmaceutical batch(es) or pharmaceutical formulation(s) comprising bivalirudin as the active ingredient, and a method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s). The pharmaceutical batch(es) or pharmaceutical formulation(s) may have a maximum impurity level of Asp9-bivalirudin that does not exceed about 0.6%. Also, the pharmaceutical batch(es) or pharmaceutical formulation(s) may have a reconstitution time that does not exceed about 42 seconds. The method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s) may comprise dissolving bivalirudin in a solvent to form a first solution, efficiently mixing a pH-adjusting solution with the first solution to form a second solution in which the pH-adjusting solution may comprise a pH-adjusting solution solvent, and removing the solvent and the pH-adjusting solution solvent from the second solution.
Abstract:
Described is a system and mechanism by which a client computer may issue a conventional request for a resource on the Web. A response to that request is annotated with information indicating that metadata is available for the resource. Specifically, a special tag or instruction may be included in the response document that indicates the existence and location of a discovery document containing metadata about the resource. The client computer may then retrieve the metadata from the location identified in the response.
Abstract:
Using a message exchanger (“message exchanger”), data messages are exchanged between entities in a decentralized, distributed, potentially heterogeneous, network environment. The message exchanger employs XML (extensible Markup Language). To accomplish this, the entities on both ends of the message exchange understand, identify, and parse the message format. The message exchanger defines such a mechanism. Data messages are broken down into two portions—one portion (the body) is intended from an ultimate destination and the other portion (the header) is intended for intermediate destination and/or the ultimate destination. The body may be defined so that it must be understood by the ultimate destination. The header may be defined so that it must be understood or changed. Regardless, the data in the body is delivered intact to the ultimate destination. The message exchanger defines a message envelope exchange format in XML over a transport protocol, such as HTTP (HyperText Transport Protocol). This format allows for the execution of RPC (Remote Procedure Call) over XML, but it can be used for any message exchange over a network.
Abstract:
A network switch having switch ports for communication of data packets with respective computer network nodes according to CSMA/CD protocol that resets a retry counter within any one of the respective switch ports if backpressure is asserted by that port. The resetting of the retry counter within a port after assertion of backpressure affords the port a greater probability of winning collision mediation under the CSMA/CD protocol, thus more quickly relieving congestion which may occur in the network switch.
Abstract:
An object system provides composable object execution environment extensions with an object model that defines a framework with contexts, policies, policy makers and activators that act as object creation-time, reference creation-time and call-time event sinks to provide processing of effects specific to the environment extensions. At object creation time, an object instantiation service of the object system delegates to the activators to establish a context in which the object is created. The context contains context properties that represent particular of the composable environment extensions in which the object is to execute. The context properties also can act as policy makers that contribute policies to an optimized policy set for references that cross context boundaries. The policies in such optimized sets are issued policy events on calls across the context boundary to process effects of switching between the environment extensions of the two contexts.