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公开(公告)号:US20060134223A1
公开(公告)日:2006-06-22
申请号:US10559173
申请日:2004-06-03
Applicant: Kazuhito Yamada
Inventor: Kazuhito Yamada
CPC classification number: A61K31/573 , A61K9/1647 , A61K31/58
Abstract: An object of the present invention is to provide a solvent which is able to produce microparticles where content of the drug is still high and no initial burst takes place even when a drug having a low solubility in a halogenated hydrocarbon solvent is used. The present invention provides a process for production by a solvent-evaporation microencapsulation method, of microparticles which are composed of biodegradable polymer and contain a drug having a low solubility in a halogenated hydrocarbon, which is characterized in that the drug and the biodegradable polymer are dissolved in a mixed solvent comprising a first solvent: halogenated hydrocarbon, and a second solvent: a water-immiscible organic solvent in which solubility of the above-mentioned drug is 0.3% (w/v) or more.
Abstract translation: 本发明的目的在于提供即使使用在卤代烃类溶剂中溶解性低的药物,也能够产生药物含量仍然很高而不发生初始爆发的微粒的溶剂。 本发明提供了一种通过溶剂蒸发微胶囊化方法生产由生物可降解聚合物组成并含有在卤代烃中具有低溶解度的药物的微粒的方法,其特征在于药物和可生物降解聚合物溶解 在包含第一溶剂:卤代烃和第二溶剂的混合溶剂中:上述药物的溶解度为0.3%(w / v)以上的与水不混溶的有机溶剂。
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公开(公告)号:US20060032668A1
公开(公告)日:2006-02-16
申请号:US11203427
申请日:2005-08-15
Applicant: Yoshinori Wakihara , Kazuhito Yamada
Inventor: Yoshinori Wakihara , Kazuhito Yamada
CPC classification number: H05K3/108 , H05K1/0269 , H05K3/067 , H05K3/244 , H05K3/3452 , H05K3/382 , H05K3/384 , H05K3/4661 , H05K2201/0989 , H05K2201/09918 , H05K2203/0307 , H05K2203/072 , Y10S428/901 , Y10T29/49002 , Y10T29/49156 , Y10T29/49167 , Y10T156/1056 , Y10T428/24917
Abstract: A printed circuit board is by formed by laminating an interlaminar insulating layer on a conductor circuit of a substrate, in which the conductor circuit is comprised of an electroless plated film and an electrolytic plated film and a roughened layer is formed on at least a part of the surface of the conductor circuit.
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公开(公告)号:US6039673A
公开(公告)日:2000-03-21
申请号:US206152
申请日:1998-12-07
Applicant: Kazuhiro Mikami , Kazuhito Yamada , Jiro Nishiwaki
Inventor: Kazuhiro Mikami , Kazuhito Yamada , Jiro Nishiwaki
CPC classification number: F16H61/0206 , F16H61/20 , B60W2540/12 , B60W30/18118 , F16H2061/205 , Y10T477/646
Abstract: A control system for an automatic transmission including a hydraulic power transmission, a clutch, and a brake which is engaged to prevent a vehicle from rolling backward thereby establishing a hill-hold state in the speed change unit. The control system includes a stop state detector which detects the vehicle stopped state when the forward driving range is selected, the accelerator pedal is released and the brake pedal is depressed. The control system further includes a clutch disengaging system which provides a neutral control, and a brake engaging system which provides a hill-hold control and performs a neutral control with the engine not under a load.
Abstract translation: 一种用于自动变速器的控制系统,包括液压动力传动装置,离合器和制动器,其被接合以防止车辆向后滚动,从而在变速单元中建立坡道保持状态。 控制系统包括停止状态检测器,当选择前进行驶范围时,检测车辆停止状态,油门踏板被释放并且制动踏板被按下。 控制系统还包括一个提供中立控制的离合器分离系统,以及一个制动接合系统,该系统提供一个坡道保持控制,并且在发动机不处于负载状态下执行空档控制。
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