公开(公告)号：US12186076B2

公开(公告)日：2025-01-07

申请号：US17171474

申请日：2021-02-09

Applicant: Medtronic, Inc.

Inventor： David L. Probst ,  Mark R. Boone

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/1486 ,  A61K49/00 ,  A61B5/00

Abstract: An example medical device includes an optical sensor, processing circuitry, an antenna, and a power source. The optical sensor includes a light source; a reference optical beacon having a first fluorophore that emits a first fluorescence proportional to a first concentration of a substance proximate the beacon; a test optical beacon having a reagent substrate that reacts with an analyte to produce the substance and a second fluorophore that emits a second fluorescence proportional to a second concentration of the substance proximate the test beacon; and a photodetector to detect the first and second fluorescence. The processing circuitry determines a difference between the first and second fluorescence, which is indicative of the concentration of the analyte. The antenna and power source enable the medical device to operate completely within a biological system for continuous analyte monitoring.

公开(公告)号：US20250001185A1

公开(公告)日：2025-01-02

申请号：US18829512

申请日：2024-09-10

Applicant: MEDTRONIC, INC.

Inventor： Xiaohong Zhou

IPC: A61N1/368 ,  A61B5/00 ,  A61B5/24 ,  A61B5/283 ,  A61B5/349 ,  A61B5/363 ,  A61B5/366 ,  A61N1/05 ,  A61N1/362 ,  A61N1/365 ,  A61N1/37 ,  A61N1/372 ,  A61N1/375 ,  A61N1/39

Abstract: The present disclosure relates generally to pacing of cardiac tissue, and more particularly to adjusting delivery of His bundle or bundle branch pacing in a cardiac pacing system to achieve synchronized ventricular activation. A left bundle branch (LBB) cathode electrode may be implanted a left side of the septum of the patient's heart proximate to the LBB, and a right bundle branch (RBB) cathode electrode may be implanted on a right side of the septum of the patient's heart proximate to the RBB. One or both cathode electrodes may be used to deliver synchronized left and right bundle-branch pacing based on one or both of an atrial event and a ventricular event. A device for bundle branch pacing may be implanted based on determining whether an LBB block pattern or an RBB block pattern is present in monitored electrical activity.

公开(公告)号：US12179025B2

公开(公告)日：2024-12-31

申请号：US18320192

申请日：2023-05-18

Applicant: Medtronic, Inc.

Inventor： David J. Peichel ,  Jonathan P. Roberts ,  James D. Reinke ,  Michael B. Terry

IPC: A61N1/372 ,  A61N1/375 ,  A61N1/39 ,  A61N1/05

Abstract: A device, such as an IMD, having a tissue conductance communication (TCC) transmitter controls a drive signal circuit and a polarity switching circuit by a controller of the TCC transmitter to generate an alternating current (AC) ramp on signal having a peak amplitude that is stepped up from a starting peak-to-peak amplitude to an ending peak-to-peak amplitude according to a step increment and step up interval. The TCC transmitter is further controlled to transmit the AC ramp on signal from the drive signal circuit and the polarity switching circuit via a coupling capacitor coupled to a transmitting electrode vector coupleable to the IMD. After the AC ramp on signal, the TCC transmitter transmits at least one TCC signal to a receiving device.

公开(公告)号：US12178566B2

公开(公告)日：2024-12-31

申请号：US17101945

申请日：2020-11-23

Applicant: Medtronic, Inc.

Inventor： David A Anderson ,  James H Borowick ,  Hyun J. Yoon ,  Jon E. Thissen ,  Shantanu Sarkar ,  Ashley L Galarneau ,  Jason C. Lee

IPC: A61B5/06 ,  A61B5/283 ,  A61B5/339

Abstract: This disclosure is directed to techniques for detecting and mitigating inaccurate sensing in a medical system. In some examples, one or more sensors of the medical system may include at least one electrode configured to sense an impedance of a portion of a patient's body proximate to the electrode and processing circuitry of the medical system may detect an inaccuracy in the data corresponding to the one or more patient physiological parameters based upon data including at least the sensed impedance of the portion of the patient body; correct at least a portion of the inaccuracy in the data corresponding to the one or more patient physiological parameters; and generate, for display on a display device, output data indicating the inaccuracy in the data corresponding to the one or more patient physiological parameters.

公开(公告)号：US12178470B2

公开(公告)日：2024-12-31

申请号：US17397276

申请日：2021-08-09

Applicant: Medtronic, Inc.

Inventor： Ronald A. Drake ,  Kevin R. Seifert ,  Lester O. Stener ,  Amy E. Thompson-Nauman

IPC: A61B17/34 ,  A61M25/01 ,  A61N1/05 ,  A61B17/32

Abstract: Extravascular implant tools that utilize a bore-in mechanism to safely access extravascular locations and implant techniques utilizing these tools are described. The bore-in mechanism may include a handle and a helix extending from the handle. The bore-in mechanism is used, for example, in conjunction with a tunneling tool to traverse the diaphragmatic attachments to access a substernal location. The tunneling tool may be an open channel tunneling tool or a conventional tunneling tool (e.g., metal rod).

公开(公告)号：US20240423794A1

公开(公告)日：2024-12-26

申请号：US18597198

申请日：2024-03-06

Applicant: Medtronic, Inc.

Inventor： Caitlin M. Owenson ,  David A. Grossman ,  Jacob A. Steiner

IPC: A61F2/24

Abstract: A delivery system includes an outer shaft including a capsule at a distal portion thereof configured to restrain a prosthetic device, an inner shaft disposed within the outer shaft, and a capture device disposed between the outer shaft and the inner shaft. The capture device is configured to retain a portion of the prosthetic device. The capture device includes: a body including a central passage, a plurality of radial openings extending from the central passage radially outward to an outer surface of the body, and a plurality of slots in the outer surface of the body; and a plurality of capture loops, each capture loop extending radially outward through a corresponding radial opening, each capture loop configured to extend through a portion of the prosthetic device, and a distal end of each capture loop configured to be releasably restrained in a corresponding slot of the plurality of slots.

公开(公告)号：US12168133B2

公开(公告)日：2024-12-17

申请号：US18298179

申请日：2023-04-10

Applicant: Medtronic, Inc.

Inventor： Rene A. Molina ,  Scott R. Stanslaski ,  Jadin C. Jackson ,  Christopher L Pulliam ,  Eric J. Panken ,  Michelle A. Case ,  Abbey Beuning Holt Becker

IPC: A61N1/36 ,  A61N1/05

Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

公开(公告)号：US12168085B2

公开(公告)日：2024-12-17

申请号：US17306053

申请日：2021-05-03

Applicant: MEDTRONIC INC.

Inventor： Sean Chen ,  Kirsten R. Stark ,  Satish Pulapura ,  Kasyap V. Seethamraju ,  Jonathan T. Goodman ,  DanThanh H. Le

IPC: A61L31/10 ,  A61K31/195 ,  A61K31/496 ,  A61K31/65 ,  A61L27/34 ,  A61L27/54 ,  A61L31/16 ,  A61N1/375 ,  A61N1/39

Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating includes a polymer, collagen, glycerin and a hemostatic agent. The polymer is selected from the group of polyhydroxybutyrate, polyglycerol sebacate and adducts of polyglycerol sebacate. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.

公开(公告)号：US20240407703A1

公开(公告)日：2024-12-12

申请号：US18812367

申请日：2024-08-22

Applicant: Medtronic, Inc.

Inventor： James D. REINKE ,  Xusheng ZHANG ,  Vinod SHARMA ,  Vladimir P. NIKOLSKI ,  Michael B. TERRY ,  Scott A. HARELAND ,  Daniel L. HANSEN ,  Donna M. SALMI

IPC: A61B5/363 ,  A61B5/00 ,  A61B5/346 ,  A61N1/37

Abstract: In situations in which an implantable medical device (e.g., a subcutaneous ICD) is co-implanted with a leadless pacing device (LPD), it may be important that the subcutaneous ICD knows when the LPD is delivering pacing, such as anti-tachycardia pacing (ATP). Techniques are described herein for detecting, with the ICD and based on the sensed electrical signal, pacing pulses and adjusting operation to account for the detected pulses, e.g., blanking the sensed electrical signal or modifying a tachyarrhythmia detection algorithm. In one example, the ICD includes a first pace pulse detector configured to obtain a sensed electrical signal and analyze the sensed electrical signal to detect a first type of pulses having a first set of characteristics and a second pace pulse detector configured to obtain the sensed electrical signal and analyze the sensed electrical signal to detect a second type of pulses having a second set of characteristics.

公开(公告)号：US12161871B2

公开(公告)日：2024-12-10

申请号：US17552866

申请日：2021-12-16

Applicant: Medtronic, Inc.

Inventor： David A. Dinsmoor ,  Timothy J. Denison ,  Xin Su

IPC: A61N1/36 ,  A61N1/05

Abstract: This disclosure relates to methods, devices, and systems for delivering and adjusting stimulation therapy. In one example, a method comprising delivering, by a stimulation electrode, electrical stimulation as a candidate therapy to a patient according to a set of candidate therapy parameters, the stimulation electrode located in proximity to the dorsal column of a patient; sensing, by a sensing electrode, an electrically evoked compound action potential (eECAP) signal in response to the delivery of the electrical stimulation; and classifying, by a processor, the sensed eECAP signal generated in response to the application of the candidate therapy relative to an eECAP baseline is disclosed.