公开(公告)号：US08948488B2

公开(公告)日：2015-02-03

申请号：US12533406

申请日：2009-07-31

Applicant: Ali Can ,  Cemal Cagatay Bilgin ,  Jens Rittscher ,  Robert John Filkins

Inventor： Ali Can ,  Cemal Cagatay Bilgin ,  Jens Rittscher ,  Robert John Filkins

IPC: G06K9/00 ,  G06T5/00

CPC classification number: G06T5/004 ,  G06T2207/10024 ,  G06T2207/30024

Abstract: Methods and systems for digitally enhancing an initial image of a material to which a plurality of stains were previously applied, that generally comprise: unmixing the image into a plurality of individual reconstructed images, each individual image corresponding to one of the stains; estimating a residual image corresponding to the difference between the original image and the reconstructed images; adjusting one or more components of the individual images; mixing the adjusted components using one or more estimated mixing coefficients; and adding the residual image to the mixed adjusted components to generate an enhanced image.

Abstract translation: 用于数字增强先前施加多个污渍的材料的初始图像的方法和系统，其通常包括：将图像混合成多个单独的重建图像，每个单独的图像对应于一个污渍; 估计对应于原始图像和重建图像之间的差的残差图像; 调整各个图像的一个或多个分量; 使用一个或多个估计的混合系数混合调整的组分; 并将残差图像添加到混合调整的分量以产生增强图像。

公开(公告)号：US08945489B2

公开(公告)日：2015-02-03

申请号：US13144774

申请日：2010-01-15

Applicant: Robert John Bowell ,  Keith Phillip Williams ,  Brian Matthew Dey

Inventor： Robert John Bowell ,  Keith Phillip Williams ,  Brian Matthew Dey

IPC: C22B5/00 ,  C25C1/00 ,  C01G49/00 ,  C22B1/08 ,  C22B1/10 ,  C22B7/00 ,  C22B7/04 ,  C22B13/02 ,  C22B15/00 ,  C22B19/28 ,  C22B19/30

CPC classification number: C22B1/08 ,  C22B1/10 ,  C22B7/002 ,  C22B7/04 ,  C22B13/025 ,  C22B15/006 ,  C22B19/28 ,  C22B19/30 ,  Y02P10/214 ,  Y02P10/22 ,  Y02P10/232

Abstract: A process for recovering a metal chloride or mixed metal chloride from a solid waste material comprising recoverable metal containing constituents produced by lead, copper or zinc smelting and refining processes, said process comprising the steps of: (i) heating the solid waste material; (ii) treating the heated material of step (i) with a gaseous chloride to form a gaseous metal chloride containing product; and (iii) treating the gaseous metal chloride containing product of step (ii) to recover the metal chloride or mixed metal chloride. The metal chloride may be further treated to extract the metal itself.

Abstract translation: 一种从固体废物中回收金属氯化物或混合金属氯化物的方法，包括由铅，铜或锌冶炼和精制方法生产的含可回收金属成分，所述方法包括以下步骤：（i）加热固体废料; （ii）用气态氯处理步骤（i）的被加热材料以形成含气态金属氯化物的产品; 和（iii）处理步骤（ii）的含有气态金属氯化物的产物以回收金属氯化物或混合金属氯化物。 可以进一步处理金属氯化物以提取金属本身。

公开(公告)号：US20150025064A1

公开(公告)日：2015-01-22

申请号：US14342339

申请日：2012-08-29

Applicant: John Howard Hutchinson ,  Leo Bleicher ,  Nick Cosford ,  Robert John Ardecky ,  Jiwen Zou

Inventor： John Howard Hutchinson ,  Leo Bleicher ,  Nick Cosford ,  Robert John Ardecky ,  Jiwen Zou

IPC: C07D403/04 ,  A61K45/06 ,  C07D417/04 ,  A61K31/551 ,  C07D243/12

CPC classification number: C07D403/04 ,  A61K31/551 ,  A61K45/06 ,  C07D243/12 ,  C07D243/14 ,  C07D409/14 ,  C07D417/04

Abstract: The present invention relates to novel benzodiazepinone compounds of Formulae (I) wherein R1, R2, R4, R6, R7, R8, R9, and R10 are as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, methods of use of such compounds and compositions, and methods for preparing the compounds and compositions. The compounds are Group II metabotropic glutamate antagonists or allosteric modulators and are useful for the treatment of a variety of CNS disorders.

Abstract translation: 本发明涉及式（I）的新的苯并二氮杂酮化合物，其中R 1，R 2，R 4，R 6，R 7，R 8，R 9和R 10如本文所定义。 本发明还涉及含有这些化合物的药物组合物，这种化合物和组合物的使用方法，以及制备化合物和组合物的方法。 化合物是II族代谢型谷氨酸拮抗剂或变构调节剂，可用于治疗各种CNS疾病。

公开(公告)号：US08892451B2

公开(公告)日：2014-11-18

申请号：US13617929

申请日：2012-09-14

Applicant: William Curtis Everett ,  Richard Ashton Hutchinson ,  Wilbert John Steigerwald, III ,  William Andrew Say ,  Patrick Lawrence O'Malley ,  Dane Allen Shrallow ,  Raymond Scott Ling ,  Robert John McMillan

Inventor： William Curtis Everett ,  Richard Ashton Hutchinson ,  Wilbert John Steigerwald, III ,  William Andrew Say ,  Patrick Lawrence O'Malley ,  Dane Allen Shrallow ,  Raymond Scott Ling ,  Robert John McMillan

IPC: G06Q40/08 ,  G07C5/00 ,  G06Q10/08

CPC classification number: G07C5/008 ,  G06Q10/0833 ,  G06Q40/08

Abstract: A data logging device tracks the operation of a vehicle or driver actions. The device includes a storage device, which may be removable or portable, having a first memory portion that may be read from and may be written to in a vehicle and a second memory portion that may be read from and may be written to in the vehicle. The second memory portion may retain data attributes associated with the data stored in the first removable storage device. A processor reads data from an automotive bus that transfers data from vehicle sensors to other automotive components. The processor writes data to the first memory portion and the second memory portion that reflect a level of risk or safety. A communication device links the storage device to a network of computers. The communication device may be accessible through software that allows a user to access files.

Abstract translation: 数据记录设备跟踪车辆或驾驶员的操作动作。 该设备包括可以是可移动的或便携式的存储设备，其具有可从车辆中读取并可被写入车辆的第一存储器部分和可以从车辆中读取并且可以被写入车辆的第二存储器部分 。 第二存储器部分可以保留与存储在第一可移动存储设备中的数据相关联的数据属性。 处理器从汽车总线读取数据，将数据从车辆传感器传输到其他汽车部件。 处理器将数据写入反映风险或安全级别的第一存储器部分和第二存储器部分。 通信设备将存储设备链接到计算机网络。 通信设备可以通过允许用户访问文件的软件来访问。

公开(公告)号：US08884969B2

公开(公告)日：2014-11-11

申请号：US13026435

申请日：2011-02-14

Applicant: Paul Edward Dangler ,  Robert John Rolleston

Inventor： Paul Edward Dangler ,  Robert John Rolleston

IPC: G06T13/00 ,  G06T15/00 ,  G06F3/12

CPC classification number: G06F3/1256 ,  G06F3/1208 ,  G06F3/1272 ,  G06F3/1282 ,  G06F3/1285 ,  G06T15/00

Abstract: A method and system for providing three-dimensional preview of a finished document based on a key feature analysis. The document can be analyzed by a document analysis algorithm configured in association with a document visualization module in order to identify a number of key features associated with the document. A viewing script can be created with respect to the key features of the document in order to drive a visualization engine. A document-specific visual animation of the key features can be visually displayed based on the viewing script at a user interface in order to preview the finished document. A list of critical features with respect to the document can be selected and previewed by a user via a set of media controls displayed at the user interface.

Abstract translation: 一种基于关键特征分析提供完成文档的三维预览的方法和系统。 可以通过与文档可视化模块相关联地配置的文档分析算法来分析文档，以便识别与该文档相关联的多个关键特征。 可以针对文档的关键特征创建查看脚本，以便驱动可视化引擎。 可以基于在用户界面处的观看脚本来可视地显示关键特征的文档特定的视觉动画，以便预览完成的文档。 可以通过用户界面上显示的一组媒体控件来选择和预览关于该文档的关键特征的列表。

公开(公告)号：US20140288475A1

公开(公告)日：2014-09-25

申请号：US14002473

申请日：2012-03-01

Applicant: Robert John Watts

Inventor： Robert John Watts

IPC: A61F5/01

CPC classification number: A61F5/0111 ,  A61F5/0113

Abstract: An ankle-foot orthosis for resisting plantarflexion of a patient's foot, the orthosis comprising: a first resiliently flexible part (1) that comprises a first portion (3) and a second portion (5) set at an angle to said first portion (3), said first portion (3) being configured to lie against and along a portion of a patient's shin in use, and said second portion (5) being configured to extend partway along a dorsal aspect of the patient's foot in use, said first part (1) further comprising means (9) operable to secure said first portion (3) against the patient's shin; and a second resiliently flexible part (7) that is separate from but co-operates with said first part (1) in use, said second part (7) comprising a tubular body that is configured and arranged to fit around the patient's foot and to overlap at least part of the second portion (5) of said first part (1); wherein said first (1) and second parts (7) co-operate to provide a resistance to flexure suitable for correcting the plantarflexion experienced by the patient.

Abstract translation: 一种用于抵抗患者足部跖屈的踝足矫形器，所述矫形器包括：第一弹性柔性部分（1），其包括第一部分（3）和与所述第一部分（3）成一定角度设置的第二部分（5） ），所述第一部分（3）被构造成位于使用中并沿着患者的胫骨的一部分，并且所述第二部分（5）构造成在使用中沿着患者的脚的背侧延伸，所述第一部分 （1）还包括可操作以将所述第一部分（3）固定在患者的胫骨上的装置（9） 以及在使用中与所述第一部分（1）分离但与所述第一部分（1）分离的第二弹性柔性部分（7），所述第二部分（7）包括管状体，所述管状体被构造和布置成适合于患者的脚部周围， 与所述第一部分（1）的第二部分（5）的至少一部分重叠; 其中所述第一部分（1）和第二部分（7）协作以提供适于校正患者所经历的跖屈的挠曲力。

公开(公告)号：US20140262164A1

公开(公告)日：2014-09-18

申请号：US14290478

申请日：2014-05-29

Applicant: Mark P. Taylor ,  John JJ Chen ,  Mohamed Farid ,  Robert John Wallace

Inventor： Mark P. Taylor ,  John JJ Chen ,  Mohamed Farid ,  Robert John Wallace

IPC: F27D9/00

CPC classification number: F27D9/00 ,  C21B7/106 ,  C21C5/4646 ,  C25C3/085 ,  F27D2009/0005 ,  F27D2009/0013 ,  Y02P10/138 ,  Y02P10/262

Abstract: A heat exchanger 10 includes a conduit 12 for conveying cooling fluid relative to a body to be cooled. A heat transfer arrangement 62 is arranged in communication with an interior of the conduit 12, the heat transfer arrangement 62 and the conduit 12 together defining an assembly that is mountable adjacent the body to be cooled, convective heat exchange occurring, in use, due to movement of the cooling fluid relative to the body and to the heat transfer arrangement 62 of the assembly and radiant heat exchange occurring between the body and at least part of the heat transfer arrangement 62 of the assembly.

Abstract translation: 热交换器10包括用于相对于要冷却的主体输送冷却流体的导管12。 传热装置62布置成与导管12，传热装置62和导管12的内部连通，该传热装置62和导管12一起限定可相对于待冷却的主体安装的组件，在使用中发生对流热交换，由于 冷却流体相对于主体和组件的传热装置62的运动以及在主体与组件的传热装置62的至少一部分之间发生的辐射热交换。

公开(公告)号：US08822147B2

公开(公告)日：2014-09-02

申请号：US13457531

申请日：2012-04-27

Applicant: Anup Sood ,  Michael Christopher Montalto ,  Michael Gerdes ,  Maximilian Lewis Seel ,  Robert John Filkins

Inventor： Anup Sood ,  Michael Christopher Montalto ,  Michael Gerdes ,  Maximilian Lewis Seel ,  Robert John Filkins

IPC: C12Q1/68 ,  G01N33/58 ,  G01N33/542 ,  G01N33/53

CPC classification number: G01N33/53 ,  C12Q1/68 ,  G01N33/542 ,  G01N33/582 ,  Y10T436/143333

Abstract: Methods for detecting multiple targets in a biological sample are provided. The methods includes contacting the sample with a first probe; physically binding the first probe to a first target; observing a first signal from the first probe; applying a chemical agent to modify the first signal; contacting the sample with a second probe; physically binding the second probe to a second target; and observing a second signal from the second probe. The methods disclosed herein also provide for multiple iterations of binding, observing, signal modification for deriving information about multiple targets in a single sample. An associated kit and device are also provided.

Abstract translation: 提供了用于检测生物样品中多个靶的方法。 所述方法包括使样品与第一探针接触; 将第一探针物理地绑定到第一靶; 观察来自第一探针的第一信号; 施用化学试剂来修饰第一信号; 使样品与第二探针接触; 将第二探针物理地绑定到第二靶上; 并观察来自第二探测器的第二信号。 本文公开的方法还提供绑定，观察，信号修改的多次迭代，用于导出关于单个样本中的多个目标的信息。 还提供了相关的套件和设备。

公开(公告)号：US20140234063A1

公开(公告)日：2014-08-21

申请号：US14241474

申请日：2012-08-24

Applicant: Robert John Goldspink

Inventor： Robert John Goldspink

IPC: E02F3/407 ,  B66F9/19

CPC classification number: E02F3/407 ,  B66F9/195 ,  E02F3/96

Abstract: A duckbill pod (100) having an ejector mechanism, the duckbill pod (100) comprising a tray (10) for providing a transport surface for goods or material, a pusher plate (50) arranged substantially perpendicular to the tray (10), a drive arrangement for actuating the pusher plate (50) and reciprocate same between a mouth and a rear end of the duckbill pod (100), and a lifting plate (20) secured to the tray (10) for attaching the duckbill pod (100) to a loader.

Abstract translation: 具有喷射器机构的鸭嘴荚（100），所述鸭嘴荚（100）包括用于提供货物或材料的输送表面的托盘（10），基本垂直于所述托盘（10）设置的推板（50）， 驱动装置，用于致动推动板（50）并在鸭嘴箱（100）的口部和后端之间往复运动;以及提升板（20），固定在托盘（10）上，用于安装鸭嘴箱（100） 到装载机

公开(公告)号：US08777684B2

公开(公告)日：2014-07-15

申请号：US13594267

申请日：2012-08-24

Applicant: James Thomas Grutta ,  Nathan Kuder ,  Peter Thomas Gompert ,  Derick Noffsinger ,  Robert John Horacek ,  Joseph Benjamin Walker ,  David Kuhlmann Blackwell

Inventor： James Thomas Grutta ,  Nathan Kuder ,  Peter Thomas Gompert ,  Derick Noffsinger ,  Robert John Horacek ,  Joseph Benjamin Walker ,  David Kuhlmann Blackwell

IPC: B63C9/18

CPC classification number: A62B33/00

Abstract: One embodiment of the present invention relates to an avalanche safety system including an inflatable chamber, activation system, inflation system, diagnostic system and a harness. The inflatable chamber is a three-dimensionally, partially enclosed region having an inflated state and a compressed state. The inflated state may form a particular three dimensional shape configured to protect the user from burial and provide flotation during an avalanche. The activation system is configured to receive a user-triggered action to activate the system. The inflation system may include an air intake, battery, fan, and internal airway channel. The inflation system is configured to transmit ambient air into the inflatable chamber. The diagnostic system includes a at least one sensor configured to measure a parameter corresponding to the inflation system and a display configured to visually, audibly, and/or tactilely display the parameter.

Abstract translation: 本发明的一个实施例涉及一种雪崩安全系统，其包括充气室，活化系统，充气系统，诊断系统和线束。 可膨胀室是具有膨胀状态和压缩状态的三维部分封闭区域。 膨胀状态可以形成特定的三维形状，其被配置为保护使用者免受埋葬，并在雪崩期间提供浮选。 激活系统被配置为接收用户触发的动作来激活系统。 充气系统可以包括进气口，电池，风扇和内部气道通道。 膨胀系统被配置为将环境空气传送到可充气室中。 所述诊断系统包括被配置为测量与所述充气系统相对应的参数的至少一个传感器，以及被配置为以视觉，听觉和/或触觉显示所述参数的显示器。