公开(公告)号：US20190153136A1

公开(公告)日：2019-05-23

申请号：US16098478

申请日：2017-05-08

Applicant: TOKUSHIMA UNIVERSITY ,  SEKISUI CHEMICAL CO., LTD.

Inventor： Koichi UTE ,  Tomohiro HIRANO ,  Miyuki OSHIMURA ,  Yasunari KUSAKA

IPC: C08F216/38 ,  C08F216/06 ,  B01J31/12

Abstract: The present invention provides a vinyl alcohol-vinyl acetate copolymer having excellent solubility and a method for producing a vinyl alcohol-vinyl acetate copolymer. Provided is a vinyl alcohol-vinyl acetate copolymer including a unit of vinyl alcohol and a unit of vinyl acetate, the vinyl alcohol-vinyl acetate copolymer having a randomness value R of 0.5 or higher, the randomness value R being obtained using the following equation (1): R = 1 L A + 1 L O ( 1 ) where LO represents a mean chain length of the unit of vinyl alcohol and LA represents a mean chain length of the unit of vinyl acetate.

公开(公告)号：US20180303093A1

公开(公告)日：2018-10-25

申请号：US15767660

申请日：2016-11-01

Applicant: AICHI STEEL CORPORATION ,  TOKUSHIMA UNIVERSITY

Inventor： Kosuke NAMBA ,  Yoshiko MURATA

IPC: A01N43/36 ,  A01N59/16

CPC classification number: A01N43/36 ,  A01N59/16 ,  C05D9/02 ,  C05F11/10 ,  C07D207/16 ,  Y02P20/55

Abstract: Provided is a novel heterocycle-containing amino acid compound that has a metal uptake ability equivalent to mugineic acids and can be less expensively produced than mugineic acids. Also provided are a fertilizer and a plant growth regulating agent each comprising the novel heterocycle-containing amino acid compound. The present invention is a heterocycle-containing amino acid compound represented by general formula (1): (wherein: R1, R2 and R3 are the same or different and represent a hydrogen atom or a carboxyl-protecting group; R4 represents a hydrogen atom or a hydroxy-protecting group; R5 represents a hydrogen atom or an amino-protecting group; and n is an integer of 1-3) or a salt thereof and use of the same.

公开(公告)号：US20180217053A1

公开(公告)日：2018-08-02

申请号：US15748261

申请日：2016-08-09

Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

Inventor： Yoshihiro DEGUCHI ,  Masaaki NAGASE ,  Michio YAMAJI ,  Nobukazu IKEDA ,  Kouji NISHINO ,  Masayoshi KAWASHIMA ,  Kazuteru TANAKA

IPC: G01N21/31 ,  G01N21/59 ,  G01J3/42

CPC classification number: G01N21/3103 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J3/433 ,  G01J2001/4242 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/33 ,  G01N21/3504 ,  G01N21/59 ,  G01N2021/3133 ,  G01N2201/0625 ,  G01N2201/0627

Abstract: A concentration measurement device including at least one light source; a measurement cell for containing a fluid to be measured; a splitter for dividing light from the light source into incident light being incident into the measurement cell and non-incident light not being incident into the measurement cell; a transmitted-light detector for detecting transmitted light that is the incident light having passed through the measurement cell; a non-incident light detector for detecting the non-incident light; and an arithmetic part for correcting a detection signal of the transmitted-light detector using a detection signal of the non-incident light detector.

公开(公告)号：US20240341270A1

公开(公告)日：2024-10-17

申请号：US18291989

申请日：2021-08-20

Applicant: JTEKT CORPORATION ,  TOKUSHIMA UNIVERSITY

Inventor： Masayuki TAKESHIMA ,  Yoshiyuki SHIBATA ,  Toshimasa SOKU ,  Kazuya NUMAZAKI ,  Fumiki MORIMATSU ,  Kentaroh TAKAGAKI ,  Maki HIRATA

IPC: A01K1/03 ,  A01K1/02 ,  A01K29/00

CPC classification number: A01K1/031 ,  A01K1/0272 ,  A01K29/005

Abstract: A management system for an experimental animal is provided. This management system includes an information identifying unit configured to identify experimental information on the experimental animal to be transported to an experiment site, and a stress value calculating unit configured to calculate a stress value indicating stress to be suffered by the experimental animal during transportation based on the experimental information. The experimental information includes at least a part of a transportation distance for the transportation of the experimental animal, a transportation period for the transportation of the experimental animal, the number of the experimental animals to be transported at a time, an age of the experimental animal, and information on pretreatment given to the experimental animal prior to the transportation.

公开(公告)号：US12012596B2

公开(公告)日：2024-06-18

申请号：US16640521

申请日：2018-08-20

Applicant: Tokushima University

Inventor： Keishi Osakabe ,  Yuriko Osakabe

IPC: C12N15/113 ,  C12N9/22 ,  C12N15/10 ,  C12N15/11

CPC classification number: C12N15/111 ,  C12N9/22 ,  C12N15/102 ,  C12N2310/20

Abstract: Provided is a method for targeting a target nucleotide sequence. The method includes introducing, into a cell: (i) CRISPR type I-D related proteins Cas5d, Cas6d, and Cas7d, or nucleic acids encoding these proteins; and (ii) a guide RNA which includes a sequence complementary to said target nucleotide sequence and common repetitive sequences derived from CRISPR gene locus before and after said complementary sequence, or a DNA encoding said guide RNA.

公开(公告)号：US20240186762A1

公开(公告)日：2024-06-06

申请号：US18523031

申请日：2023-11-29

Applicant: TOKUSHIMA UNIVERSITY ,  NICHIA CORPORATION

Inventor： Tetsuro KATAYAMA ,  Takeshi KIHARA

IPC: H01S3/16 ,  H01S3/02

CPC classification number: H01S3/163 ,  H01S3/027

Abstract: The laser element includes a gain medium and a photochromic compound that receives a carrier from the gain medium. The gain medium may contain: a first ion including at least one selected from the group consisting of an alkali metal ion, an ammonium ion, a formamidinium ion, a guanidium ion, an imidazolium ion, a pyridinium ion, a pyrrolidinium ion, and a protonated thiourea ion; a second ion including at least one selected from the group consisting of lead, germanium, tin, antimony, and bismuth; and an anion or a ligand including at least one selected from the group consisting of a chloride ion, a bromide ion, an iodide ion, a cyanide ion, a thiocyanate, an isothiocyanate, and a sulfide.

公开(公告)号：US11939290B2

公开(公告)日：2024-03-26

申请号：US17270334

申请日：2019-08-22

Applicant: TOKUSHIMA UNIVERSITY ,  AICHI STEEL CORPORATION

Inventor： Kosuke Namba ,  Motofumi Suzuki ,  Akane Mera

IPC: C07D207/16 ,  A01N43/36 ,  A01N59/16 ,  C05C11/00 ,  C07F15/02

CPC classification number: C07D207/16 ,  A01N43/36 ,  A01N59/16 ,  C05C11/00 ,  C07F15/02

Abstract: The present invention is a heterocycle-containing amino acid compound represented by a general formula (1):




wherein R1 and R2 are identical with or different from each other, and each represent a hydrogen atom or a carboxy-protecting group;
R3 represents a carboxyl group or a hydroxyl group; and
n is 1 or 2,
or a salt thereof.

公开(公告)号：US20240074417A1

公开(公告)日：2024-03-07

申请号：US18261759

申请日：2021-03-04

Applicant: JTEKT CORPORATION ,  Tokushima University

Inventor： Nozomu MIURA ,  Yasuhiro MURATA ,  Shigekazu KAWAI ,  Takahito WATANABE ,  Taro MITO

IPC: A01K67/033

CPC classification number: A01K67/0339

Abstract: Provided is a breeding apparatus that can facilitate disposition and collection of a spawning bed. A breeding apparatus includes a breeding area forming member that forms breeding areas for organisms and is open at least at the bottoms of the breeding areas, and a spawning bed sheet that forms the bottom surfaces of the breeding areas, has a belt shape, and is provided so as to be movable in a longitudinal direction of the belt shape relative to the breeding area forming member.

公开(公告)号：US20230137078A1

公开(公告)日：2023-05-04

申请号：US17905238

申请日：2020-12-10

Applicant: AICHI STEEL CORPORATION ,  TOKUSHIMA UNIVERSITY

Inventor： Akane MERA ,  Motofumi SUZUKI ,  Kensuke HOSODA ,  Kosuke NAMBA

IPC: A01N43/36 ,  C07D207/273 ,  A01P21/00 ,  C07F15/02 ,  C05C11/00

Abstract: A lactam compound and a salt thereof, represented by general formulae (1) and (2): In the formulae, R1 and R2 may be the same or different, and each represent a hydrogen atom, a protective group of a carboxyl group or a cation, and X− is a halogen ion, an organic acid ion, or an inorganic acid ion.

公开(公告)号：US20220098256A1

公开(公告)日：2022-03-31

申请号：US17297986

申请日：2019-11-28

Applicant: TOKUSHIMA UNIVERSITY ,  ONCOTHERAPY SCIENCE, INC.

Inventor： TOYOMASA KATAGIRI ,  TETSURO YOSHIMARU ,  AKIRA OTAKA ,  TAKASHI MIYAMOTO ,  YASUHIDE OKAMOTO

IPC: C07K14/47 ,  A61P35/00

Abstract: The present invention provides peptides containing the BIG3 polypeptide-binding site in a PHB2 polypeptide, which inhibit the binding between a PHB2 polypeptide and a BIG3 polypeptide, and pharmaceutical compositions containing the peptide. The peptides of the present invention have the ability to bind not to PHB2, whose expression is found in organs throughout the human body, but to BIG3, which is a protein highly expressed specifically in particularly estrogen receptor-positive cancer, and have excellent growth suppressive effects on BIG3-positive cancer cells. Accordingly, the peptides of the present invention are useful as therapeutic agents for breast cancer which can avoid expression of side effects.