WIDE-FIELD SPECTRAL IMAGING SYSTEM
    1.
    发明公开

    公开(公告)号:US20240230406A1

    公开(公告)日:2024-07-11

    申请号:US18393636

    申请日:2023-12-21

    摘要: The present invention provides a wide-filed spectral imaging system including a laser generator, a wavelength adjustment module, an objective lens, and a single-pixel imaging and a spectral separating module. The laser generator is configured to generate a laser excitation beam. The wavelength adjustment module is configured to disperse the laser excitation beam into a plurality of beams of different wavelengths. The objective lens is configured to focus the plurality of beams of different wavelengths on a sample to excite molecules under test in the sample and generate an emission light. The single-pixel imaging and spectral separating module is configured to generate a series of patterns and modulate the emission light with the series of patterns to generate a diffracted beam. The single-pixel imaging and spectral separating module further disperses the wavelength of the diffracted beam, collects light signals of the expanded diffracted beam, and performs a spectral image reconstruction.

    IMMERSION IMAGING SYSTEMS AND METHODS FOR FLOWCELLS

    公开(公告)号:US20240151582A1

    公开(公告)日:2024-05-09

    申请号:US18483765

    申请日:2023-10-10

    IPC分类号: G01J3/28 G01J3/02 G01J3/10

    摘要: Systems and methods for immersion imaging of a flowcell. In one example, an imaging system includes liquid ports in leading and trailing positions relative to a scanned imaging objective. The leading liquid port dispenses an immersion liquid into a space between the distal end of the imaging objective and the flowcell's cover, with the trailing liquid port collecting the immersion liquid. In another example, an imaging system includes a flowcell with a cover that is moveable relative a substrate. The system is configured to move the imaging objective and flowcell cover as a unit relative to the flowcell substrate.