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公开(公告)号:US20240230406A1
公开(公告)日:2024-07-11
申请号:US18393636
申请日:2023-12-21
发明人: Fan-Ching Chien , Kun-Yu Lai , Ching-Lung Luo
CPC分类号: G01J3/2823 , G01J3/0208 , G01J3/021 , G01J3/027 , G01J3/06 , G01J3/10 , G01J3/18 , G01J2003/064 , G01J2003/069 , G01J2003/1213 , G01J2003/2826
摘要: The present invention provides a wide-filed spectral imaging system including a laser generator, a wavelength adjustment module, an objective lens, and a single-pixel imaging and a spectral separating module. The laser generator is configured to generate a laser excitation beam. The wavelength adjustment module is configured to disperse the laser excitation beam into a plurality of beams of different wavelengths. The objective lens is configured to focus the plurality of beams of different wavelengths on a sample to excite molecules under test in the sample and generate an emission light. The single-pixel imaging and spectral separating module is configured to generate a series of patterns and modulate the emission light with the series of patterns to generate a diffracted beam. The single-pixel imaging and spectral separating module further disperses the wavelength of the diffracted beam, collects light signals of the expanded diffracted beam, and performs a spectral image reconstruction.
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公开(公告)号:US12026900B2
公开(公告)日:2024-07-02
申请号:US16234360
申请日:2018-12-27
IPC分类号: G06T7/521 , A61B1/00 , A61B1/04 , A61B1/045 , A61B1/05 , A61B1/06 , G01J3/02 , G01J3/10 , G01J3/28 , G02B23/24 , H04N5/265 , H04N5/272 , H04N13/239 , H04N23/10 , H04N23/13 , H04N23/45 , H04N23/56 , H04N23/74 , H04N23/741 , H04N23/84 , H04N25/53 , H04N25/533 , H04N23/50
CPC分类号: G06T7/521 , A61B1/0005 , A61B1/00066 , A61B1/00096 , A61B1/00186 , A61B1/00193 , A61B1/043 , A61B1/045 , A61B1/05 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0653 , A61B1/0661 , G01J3/027 , G01J3/10 , G01J3/2803 , G01J3/2823 , G02B23/2461 , G02B23/2484 , H04N5/265 , H04N5/272 , H04N13/239 , H04N23/125 , H04N23/13 , H04N23/45 , H04N23/56 , H04N23/74 , H04N23/741 , H04N23/84 , H04N25/53 , H04N25/533 , G01J2003/2826 , G06T2207/10024 , G06T2207/10028 , G06T2207/10068 , G06T2207/30004 , H04N23/555
摘要: An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.
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公开(公告)号:US12005451B2
公开(公告)日:2024-06-11
申请号:US17256348
申请日:2019-06-28
CPC分类号: B01L3/502753 , F01M11/10 , G01J3/10 , G01N33/2858 , G01N33/2888 , B01L2300/0681 , F01M2011/1413 , F01M2011/144
摘要: The invention provides a microfluidic system for monitoring the condition of lubricating oil. The microfluidic system comprises a microfluidic device with at least one microchannel (40) configured to allow a sample of lubricating oil (52a) to pass therethrough as a laminar flow. The device has at least one separating device (41) configured to selectively separate at least one component (54b) from the lubricating oil (52a) in the fluid flow. The microfluidic system also comprises a detector device (20, 22) configured to detect the presence and/or measure at least one property of the at least one component passing through the microfluidic device after separation in the microchannel (40).
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公开(公告)号:US11988557B2
公开(公告)日:2024-05-21
申请号:US17545106
申请日:2021-12-08
CPC分类号: G01J3/44 , G01J3/10 , G01N21/65 , G01J3/0218
摘要: Methods and systems are described for use in determination of the presence, type (static or AC), direction, and/or strength of an electric field. Methods include examination of a gaseous sample to determine the presence of perturbation effects brought about by dielectrophoretic forces acting on components of the gaseous sample, and thereby, to identify the presence of an electric field. Examination of a gaseous sample can include Raman spectroscopy. A gaseous sample can be analyzed to determine the presence of molecular polarization due to an induced dipole on a polarizable molecule.
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公开(公告)号:US20240151582A1
公开(公告)日:2024-05-09
申请号:US18483765
申请日:2023-10-10
申请人: MGI Tech Co., Ltd.
发明人: Paul Lundquist , Razvan Chirita
CPC分类号: G01J3/2803 , G01J3/0208 , G01J3/10
摘要: Systems and methods for immersion imaging of a flowcell. In one example, an imaging system includes liquid ports in leading and trailing positions relative to a scanned imaging objective. The leading liquid port dispenses an immersion liquid into a space between the distal end of the imaging objective and the flowcell's cover, with the trailing liquid port collecting the immersion liquid. In another example, an imaging system includes a flowcell with a cover that is moveable relative a substrate. The system is configured to move the imaging objective and flowcell cover as a unit relative to the flowcell substrate.
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公开(公告)号:US11967799B2
公开(公告)日:2024-04-23
申请号:US15508889
申请日:2015-08-28
发明人: Jules Braddell , Frank Smyth
IPC分类号: H01S5/065 , G01J3/10 , G01J3/42 , G01N21/31 , G01N21/3504 , G01N21/39 , G01N21/45 , H01S5/00 , H01S5/042 , H01S5/10 , H01S5/40
CPC分类号: H01S5/0656 , G01J3/10 , G01J3/42 , G01N21/3504 , H01S5/0064 , H01S5/0085 , H01S5/0427 , H01S5/1096 , H01S5/4006 , G01N2021/3133 , G01N2021/3148 , G01N2021/399 , G01N2021/451 , G01N2201/0612
摘要: A method of performing spectroscopic measurements provides an optical frequency comb, and directs the comb through or at a sample. The optical frequency comb is generated by gain switching a laser diode constructed from Gallium Nitride and related materials. Various techniques are described for manipulating the comb source to achieve desired benefits for spectroscopy.
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公开(公告)号:US11957460B2
公开(公告)日:2024-04-16
申请号:US16777855
申请日:2020-01-30
申请人: LifePlus Inc
发明人: Kevin Hazen , Alan Abul-Haj , Roxanne Abul-Haj , Christopher Slawinski , Alodeep Sanyal , Benjamin Mbouombouo
IPC分类号: A61B5/1455 , A61B5/00 , A61B5/145 , G01J3/10 , G01N33/49
CPC分类号: A61B5/1455 , A61B5/0022 , A61B5/0051 , A61B5/0053 , A61B5/14532 , A61B5/6824 , A61B5/6832 , G01J3/10 , G01N33/49 , A61B5/0004 , A61B5/7264 , A61B2562/0233 , A61B2562/0238 , A61B2562/046 , G01J2003/102 , G01J2003/106
摘要: The invention comprises a method and apparatus for sampling a common tissue volume and/or a common skin layer skin of a person as a part of noninvasively determining an analyte property with an analyzer including: a set of detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including a first and second range of detection zones of differing radial distances from a first illumination zone and second illumination zone, respectively coupled to separate sources, with surface paths between the sources and detectors overlapping a common skin area during use.
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公开(公告)号:US20240094130A1
公开(公告)日:2024-03-21
申请号:US18214507
申请日:2023-06-26
申请人: SHIMADZU CORPORATION
发明人: Fumiya KATSUTANI , Tomoki SASAYAMA , Tomoyo TAO , Atsuhiko OTAGURO , Ryuta SHIBUTANI , Hisato FUKUDA
CPC分类号: G01N21/65 , G01J3/0208 , G01J3/10 , G01J3/44 , G02B21/06 , G01J2003/102
摘要: A Raman infrared compound microscope device includes: a first light source that generates laser light; a second light source that generates infrared light; a third light source that generates visible light; and a first optical system. The first optical system orients the visible light having reached the first optical system in different directions between when performing a Raman analysis using Raman light generated from a sample by irradiation of the laser light and when performing a first infrared analysis using the infrared light having passed through the sample.
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公开(公告)号:US20240060895A1
公开(公告)日:2024-02-22
申请号:US18496681
申请日:2023-10-27
申请人: Illumina, Inc.
发明人: Rui JIANG , Joseph PINTO
IPC分类号: G01N21/64 , C12Q1/6869 , G01J3/10 , G02B27/09
CPC分类号: G01N21/6428 , C12Q1/6869 , G01J3/10 , G01N21/6452 , G01N21/6456 , G02B27/0994 , G01N2021/6419 , G01N2021/6439 , G01N2021/6463 , G01N2201/0638 , G01N2201/08 , G01N2201/0806 , H01L27/14612
摘要: There is set forth herein a light energy exciter that can include one or more light sources. A light energy exciter can emit excitation light directed toward a detector surface that can support biological or chemical samples.
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公开(公告)号:US11892281B2
公开(公告)日:2024-02-06
申请号:US17655899
申请日:2022-03-22
发明人: Shiro Kawaguchi , Kazuya Nakajima , Hayato Takizawa , Goro Maeda
IPC分类号: G01B11/06 , G01J3/02 , G01J3/10 , G01B5/00 , G01N21/27 , G01B9/02055 , G01J3/28 , G01N21/25 , G01B21/04
CPC分类号: G01B11/0625 , G01B5/0014 , G01B9/0207 , G01B11/06 , G01B11/0675 , G01B21/045 , G01J3/02 , G01J3/027 , G01J3/0232 , G01J3/0286 , G01J3/0291 , G01J3/0297 , G01J3/10 , G01J3/28 , G01N21/25 , G01N21/274 , G01N21/276 , G01J2003/2836
摘要: An optical measurement system includes a light source, a spectroscopic detector, a reference sample, a switching mechanism that switches between a first optical path through which a sample to be measured is irradiated with light from the light source and light produced at the sample is guided to the spectroscopic detector and a second optical path through which the reference sample is irradiated with light from the light source and light produced at the reference sample is guided to the spectroscopic detector, and a processing unit that calculates, by performing correction processing based on change between a first detection result at first time and a second detection result at second time, a measurement value of the sample from a third detection result provided from the spectroscopic detector as a result of irradiation of the sample with light from the light source at third time temporally proximate to the second time.
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