公开(公告)号：US20100016962A1

公开(公告)日：2010-01-21

申请号：US12522949

申请日：2008-01-11

Applicant: Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang

Inventor： Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang

IPC: A61F2/16

CPC classification number: A61F2/1602 ,  A61F2/1618 ,  A61F2/1654

Abstract: In one aspect, the present invention provides a method of correcting vision, which comprises determining a residual accommodation exhibited by a natural, crystalline lens of an eye, and selecting a multifocal intraocular lens (IOL), which exhibits a far-focus optical power (e.g., in a range of about −15 to about +50 Diopters (D)) and an add power (e.g., in a range of about 1 D to about 4 D), for implantation in the eye while retaining the natural lens. The add power of the IOL is selected as a function of the residual accommodation such that a combination of the IOL and the natural lens provides a visual contrast greater than about 10% at a spatial frequency of about 20 cycles/degree for viewing objects at a distance greater than about 30 cm from the eye.

Abstract translation: 一方面，本发明提供了一种矫正视力的方法，其包括确定由天然眼晶体显示的残留调节物，以及选择呈现远焦光功率的多焦点人工晶状体（IOL） 例如，在约-15至约+50屈光度（D）的范围内）和附加功率（例如，在约1至约4D的范围内），用于植入眼睛同时保持天然晶状体。 选择IOL的附加功率作为残余调节的函数，使得IOL和自然透镜的组合在大约20个循环/度的空间频率处提供大于约10％的视觉对比度，以便在 距离距离眼睛约30厘米。

公开(公告)号：US20090237615A1

公开(公告)日：2009-09-24

申请号：US12417290

申请日：2009-04-02

Applicant: Kamal K. Das ,  Xiaoxiao Zhang ,  Mutlu Karakelle ,  Xin Hong

Inventor： Kamal K. Das ,  Xiaoxiao Zhang ,  Mutlu Karakelle ,  Xin Hong

IPC: A61B3/10 ,  A61F2/14

CPC classification number: A61F2/142 ,  A61F2/145 ,  A61F2/16 ,  A61F9/007 ,  A61F2009/00848 ,  A61F2009/00851 ,  A61F2240/00 ,  A61F2240/001 ,  A61F2240/002

Abstract: In one aspect, the present invention provides a method of designing an ocular implant (e.g., an IOL), which comprises establishing corneal topography of a patient's eye, e.g., by performing one or more wavefront aberration measurements of the eye, prior to an ocular surgery. The method further includes ascertaining an astigmatic aberration of the cornea that is expected to be induced by the surgery and determining a toricity of a surface of an ocular implant, which is intended for implantation in the patient's eye, so as to enable the implant to compensate for the surgically-induced aberration.

Abstract translation: 一方面，本发明提供了一种设计眼部植入物（例如，IOL）的方法，其包括建立患者眼睛的角膜形貌，例如通过在眼睛之前执行眼睛的一个或多个波前像差测量 手术。 该方法还包括确定期望由手术引起的角膜的像散像差，并确定旨在植入患者眼睛中的眼部植入物的表面的复曲面，以使植入物能够补偿 用于手术诱发的像差。

公开(公告)号：US20090164008A1

公开(公告)日：2009-06-25

申请号：US11963098

申请日：2007-12-21

Applicant: Xin Hong ,  Drew Morgan

Inventor： Xin Hong ,  Drew Morgan

IPC: A61F2/16

CPC classification number: G02B5/1876 ,  A61F2/164 ,  A61F2/1645 ,  A61F2/1654 ,  G02B3/04 ,  G02B3/06 ,  G02B3/08 ,  Y10T82/10 ,  Y10T82/16016 ,  Y10T82/2502

Abstract: In one aspect, the present invention provides an intraocular lens (IOL) that includes an optic comprising an anterior surface, a posterior surface, and a plurality of diffractive zones disposed on one of those surfaces. The surface having the diffractive zones has a profile characterized by a combination of aspheric and toric components.

Abstract translation: 一方面，本发明提供一种眼内透镜（IOL），其包括光学元件，其包括前表面，后表面和设置在这些表面之一上的多个衍射区。 具有衍射区的表面具有由非球面和复曲面组分组合的特征。

公开(公告)号：US07476248B2

公开(公告)日：2009-01-13

申请号：US10819020

申请日：2004-04-06

Applicant: Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren E. Hill

Inventor： Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren E. Hill

IPC: A61F2/14 ,  A61F2/16

CPC classification number: A61F2/1645 ,  A61F2/142 ,  A61F2240/001 ,  G02C7/028

Abstract: A method for calculating the required cylindrical power of a toric implant by using both the measured pre-operative corneal/ocular astigmatism and the predicted surgically-induced astigmatism. The post-operative corneal/ocular astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required spherocylindrical refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.

Abstract translation: 通过使用测量的术前角膜/眼像散和预测的手术引起的散光来计算复曲面植入物所需的圆柱形力的方法。 使用外科医生使用的手术技术的功率矢量分析来预测术后角膜/眼部散光。 这种方法提供了一种更准确的计算植入物所需的柱心外屈光力的方法。 该方法可以手动实现，但是优选地通过在计算机上通过适当的软件实现自动化。

公开(公告)号：US20070268453A1

公开(公告)日：2007-11-22

申请号：US11435905

申请日：2006-05-17

Applicant: Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang

Inventor： Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang

IPC: G02C7/02

CPC classification number: A61F2/141 ,  A61B3/0025 ,  A61F2/1637 ,  A61F2240/001 ,  A61F2240/008

Abstract: In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Abstract translation: 一方面，本发明提供一种设计眼内透镜（IOL）以解决患者眼睛中的至少一个眼睛参数的变化的方法。 该方法可以包括建立至少一个眼睛模型，其中眼睛参数可以在群体表现的范围上变化。 可以使用眼睛模型来评估多个IOL设计，以校正患者群体中的眼睛的视力。 然后可以选择提供最适合视觉性能的IOL设计，至少部分参数范围。

公开(公告)号：US20070182917A1

公开(公告)日：2007-08-09

申请号：US11350437

申请日：2006-02-09

Applicant: Xiaoxiao Zhang ,  Richard Mackool ,  Xin Hong ,  Michael Southard

Inventor： Xiaoxiao Zhang ,  Richard Mackool ,  Xin Hong ,  Michael Southard

IPC: G02C7/02

CPC classification number: A61F2/1654 ,  A61F2/1618

Abstract: An intraocular lens device that includes an intraocular lens optics that provides at least two powers of magnification one being near vision power and the other being distance vision power. The lens optics has surface modulations that are responsible for providing the near vision power. The zone structure provides an add power of over 6 diopters. The add power indicative of an extent that the near vision focusing power is greater than the distance vision focusing power.

Abstract translation: 一种眼内透镜装置，其包括眼内透镜光学元件，其提供至少两个放大倍率的功率，其是近视力，另一个是距离视力。 透镜光学器件具有负责提供近视力的表面调制。 区域结构提供超过6屈光度的附加功率。 附加功率表示近视聚焦功率大于距离视觉聚焦功率的程度。

公开(公告)号：US20050225721A1

公开(公告)日：2005-10-13

申请号：US10819020

申请日：2004-04-06

Applicant: Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren Hill

Inventor： Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren Hill

IPC: A61B3/00 ,  A61F2/16

CPC classification number: A61F2/1645 ,  A61F2/142 ,  A61F2240/001 ,  G02C7/028

Abstract: A method for calculating the required cylindrical power of a toric implant by using both the measured pre-operative corneal/ocular astigmatism and the predicted surgically-induced astigmatism. The post-operative corneal/ocular astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required spherocylindrical refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.

Abstract translation: 通过使用测量的术前角膜/眼像散和预测的手术引起的散光来计算复曲面植入物所需的圆柱形力的方法。 使用外科医生使用的手术技术的功率矢量分析来预测术后角膜/眼部散光。 这种方法提供了一种更准确的计算植入物所需的柱心镜屈光力的方法。 该方法可以手动实现，但是优选地通过在计算机上通过适当的软件实现自动化。

公开(公告)号：US09579191B2

公开(公告)日：2017-02-28

申请号：US13439080

申请日：2012-04-04

Applicant: Xin Hong ,  David Meadows ,  Qiwen Zhan ,  Mutlu Karakelle

Inventor： Xin Hong ,  David Meadows ,  Qiwen Zhan ,  Mutlu Karakelle

IPC: A61F2/16 ,  G02B1/115 ,  A61F2/00 ,  G02B1/118 ,  B82Y20/00 ,  G02C7/04

CPC classification number: G02B1/118 ,  A61F2/0077 ,  A61F2/16 ,  A61F2002/1696 ,  A61F2002/1699 ,  B82Y20/00 ,  G02B1/115 ,  G02B2207/101 ,  G02C7/04 ,  G02C7/049

Abstract: An ophthalmic lens system comprises a lens body with a curved outer surface and an assembly including a plurality of spaced apart nanostructures. The assembly covers at least a portion of the curved outer surface.

Abstract translation: 一种眼用透镜系统包括具有弯曲外表面的透镜体和包括多个间隔开的纳米结构的组件。 组件覆盖弯曲外表面的至少一部分。

公开(公告)号：US08764822B2

公开(公告)日：2014-07-01

申请号：US12328092

申请日：2008-12-04

Applicant: Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren E. Hill

Inventor： Blake Harris ,  James Hoffman ,  Xin Hong ,  Xiaoxiao Zhang ,  Warren E. Hill

IPC: A61F2/14

CPC classification number: A61F2/1645 ,  A61F2/142 ,  A61F2240/001 ,  G02C7/028

Abstract: A method for calculating the required power of a toric implant by using both the measured pre-operative corneal astigmatism and the predicted surgically-induced post-operative astigmatism. The surgically-induced post-operative astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required post-operative refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.

Abstract translation: 通过使用测量的术前角膜散光和预测的手术引起的术后散光来计算复曲面植入物所需功率的方法。 使用外科医生使用的手术技术的功率矢量分析来预测手术引起的术后散光。 这种方法提供了计算植入物所需的术后屈光力的更精确的方法。 该方法可以手动实现，但是优选地通过在计算机上通过适当的软件实现自动化。

公开(公告)号：US20120290085A1

公开(公告)日：2012-11-15

申请号：US13562143

申请日：2012-07-30

Applicant: Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang ,  Michael Simpson ,  Myoung Choi ,  Yan Zhang

Inventor： Xin Hong ,  Mutlu Karakelle ,  Xiaoxiao Zhang ,  Michael Simpson ,  Myoung Choi ,  Yan Zhang

IPC: A61F2/16

CPC classification number: G02C7/044 ,  A61F2/1613 ,  G02C7/042

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract translation: 一方面，本发明提供一种眼科镜片（例如，IOL），其包括具有围绕光轴设置的前表面和后表面的光学元件。 至少一个表面（例如，前表面）具有由基体轮廓和辅助轮廓叠加来表征的轮廓。 辅助轮廓可以包括内部区域，外部区域和内部区域和外部区域之间的过渡区域，其中穿过过渡区域的光程差（即，内部和外部径向边界之间的光程差） 过渡区域）对应于设计波长（例如，约550nm的波长）的非整数分数（例如，1/2）。