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公开(公告)号：US09365567B2
公开(公告)日：2016-06-14
申请号：US14502157
申请日：2014-09-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D471/04 , A61K31/4745 , C07D413/14
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。
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公开(公告)号：US20150168614A1
公开(公告)日：2015-06-18
申请号：US14104405
申请日：2013-12-12
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： David B. Running , Shri Niwas , Matthew R. Lehmann , Douglas J. Hall , Kenneth L. Hanzalik , Denise A. Barrera , Alyson C. Phillips , Loretta L. Lucas
CPC classification number: G02B5/124 , A41D31/325 , B32B38/0004 , B32B2305/22 , B32B2307/416 , G02B5/12 , Y10T156/1056
Abstract: Provided is a retroreflective article comprising a fibrous material and a perforated retroreflective material attached to said fibrous material. Embodiments of the article achieve desirable values under the ASTM F2731-11 Transmitted and Stored Energy Test, the E96/E96M-12 Moisture Vapor Transmission Rate Test, and ASTM E810-03 (2013) Standard Test Method for Coefficient of Retroreflection of Retroreflective Sheeting Utilizing the Coplanar Geometry.
Abstract translation: 提供了一种包括纤维材料和连接到所述纤维材料上的穿孔回射材料的回射制品。 该文章的实施例根据ASTM F2731-11传输和储存能量测试，E96 / E96M-12水分蒸气透过率测试和ASTM E810-03（2013）使用逆向反射片的逆反射系数的标准测试方法达到理想的值 共面几何。
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公开(公告)号：US20150023990A1
公开(公告)日：2015-01-22
申请号：US14502157
申请日：2014-09-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D471/04
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。
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