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公开(公告)号：US10144735B2
公开(公告)日：2018-12-04
申请号：US16016933
申请日：2018-06-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , George W. Griesgraber , Tushar A. Kshirsagar
IPC: A61K39/395 , C07D471/04 , A61K47/66 , A61K47/68
Abstract: The present invention provides an immune response modifier (IRM) composition that includes an IRM moiety and a second active moiety covalently linked to the IRM moiety, wherein the covalent link comprises a labile bond directly attached to the IRM moiety.
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公开(公告)号：US09546184B2
公开(公告)日：2017-01-17
申请号：US14732815
申请日：2015-06-08
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Ryan B. Prince , Bryon A. Merrill , Philip D. Heppner , Tushar A. Kshirsagar , Joshua R. Wurst , Karl J. Manske , Michael J. Rice
IPC: C07D513/04 , C07D519/00
CPC classification number: C07D513/04 , C07D519/00
Abstract: Thiazoloquinolines and thiazolonaphthyridines with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Abstract translation: 含有这些化合物的化合物，中间体，制备方法和这些化合物作为免疫调节剂的使用方法的6,7,8或9位具有烷氧基取代基的噻唑并喹啉和噻唑并萘并用于诱导动物中的细胞因子生物合成 公开了包括病毒和肿瘤疾病在内的疾病的治疗。
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公开(公告)号：US20160280707A1
公开(公告)日：2016-09-29
申请号：US15181068
申请日：2016-06-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D471/04 , C07D519/00
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
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公开(公告)号：US09856254B2
公开(公告)日：2018-01-02
申请号：US15181068
申请日：2016-06-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D413/14 , C07D519/00 , A61K31/4745 , C07D471/04
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
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Patent Agency Ranking
公开(公告)号：US20170176426A1
公开(公告)日：2017-06-22
申请号：US15450085
申请日：2017-03-06
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Tushar A. Kshirsagar , Thomas E. Wood
IPC: G01N33/543 , G01N33/552 , G01N33/553
CPC classification number: G01N33/54313 , C12N1/02 , C12N11/14 , C12Q1/04 , C12Q1/24 , G01N33/552 , G01N33/553
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to about 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration agent with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration agent.
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公开(公告)号：US20140011253A1
公开(公告)日：2014-01-09
申请号：US14023782
申请日：2013-09-11
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Tushar A. Kshirsagar , Thomas E. Wood
IPC: C12N11/14
CPC classification number: C12N11/14 , B01J20/02 , B01J20/06 , B01J20/14 , B01J20/3204 , B01J20/3234 , B01J20/3236 , C12N1/02 , C12Q1/04 , C12Q1/24
Abstract: A concentration agent for capture of microorganisms, including diatomaceous earth bearing, on at least a portion of its surface, a surface treatment comprising a surface modifier comprising titanium dioxide, fine-nanoscale gold or platinum, or a combination thereof, and methods for making the concentration agent.
Abstract translation: 用于在其表面的至少一部分上捕获包括硅藻土轴承的微生物的浓缩剂，包括包含二氧化钛，细纳米金或铂或其组合的表面改性剂的表面处理，以及用于制备 浓缩剂。
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公开(公告)号：US09365567B2
公开(公告)日：2016-06-14
申请号：US14502157
申请日：2014-09-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D471/04 , A61K31/4745 , C07D413/14
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。
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公开(公告)号：US08951575B2
公开(公告)日：2015-02-10
申请号：US14023782
申请日：2013-09-11
Applicant: 3M Innovative Properties Company
Inventor： Manjiri T. Kshirsagar , Tushar A. Kshirsagar , Thomas E. Wood
IPC: A61K33/24 , C12Q1/02 , C12Q1/24 , C12N11/14 , B01J20/02 , B01J20/06 , B01J20/14 , B01J20/32 , C12N1/02 , C12Q1/04
CPC classification number: C12N11/14 , B01J20/02 , B01J20/06 , B01J20/14 , B01J20/3204 , B01J20/3234 , B01J20/3236 , C12N1/02 , C12Q1/04 , C12Q1/24
Abstract: A concentration agent for capture of microorganisms, including diatomaceous earth bearing, on at least a portion of its surface, a surface treatment comprising a surface modifier comprising titanium dioxide, fine-nanoscale gold or platinum, or a combination thereof, and methods for making the concentration agent.
Abstract translation: 用于在其表面的至少一部分上捕获包括硅藻土轴承的微生物的浓缩剂，包括包含二氧化钛，细纳米金或铂或其组合的表面改性剂的表面处理，以及用于制备 浓缩剂。
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公开(公告)号：US20150023990A1
公开(公告)日：2015-01-22
申请号：US14502157
申请日：2014-09-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kyle J. Lindstrom , Bryon A. Merrill , Chad A. Haraldson , Michael J. Rice , Tushar A. Kshirsagar , Philip D. Heppner , Joshua R. Wurst , Shri Niwas , Sarah J. Slania
IPC: C07D471/04
CPC classification number: C07D471/04 , A61K31/4745 , C07D413/14 , C07D519/00 , Y02A50/409 , Y02A50/411 , Y02A50/463
Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
Abstract translation: 含有6,7,8或9位烷氧基取代基的咪唑并喹啉化合物含有化合物，中间体，制备方法，以及这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成， 在包括病毒和肿瘤的疾病的治疗中。
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