公开(公告)号：US20080123098A1

公开(公告)日：2008-05-29

申请号：US11556357

申请日：2006-11-03

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： G01B9/02

CPC分类号： G06K9/2036 ,  G06K9/00577

摘要： A method and system for performing device identification is disclosed. A source signal may be directed from an energy source towards the surface of a device for reflection therefrom. An interference pattern may be detected from the surface of the device, such as by a sensor. A determination as to whether a match exists between the representation of the interference pattern and a stored representation of an interference pattern may be performed. If a match exists, the device may be identified based on the stored representation of the interference pattern. Otherwise, a representation of the interference pattern may be stored and a unique identifier may be assigned to the stored representation of the interference pattern.

摘要翻译： 公开了一种用于执行设备识别的方法和系统。 源信号可以从能量源朝向装置的表面引导以从其反射。 可以从设备的表面（例如通过传感器）检测干涉图案。 可以执行关于在干涉图案的表示和存储的干涉图案的表示之间是否存在匹配的确定。 如果存在匹配，则可以基于存储的干涉图案的表示来识别该设备。 否则，可以存储干扰图案的表示，并且可以将唯一标识符分配给所存储的干涉图案的表示。

公开(公告)号：US07089059B1

公开(公告)日：2006-08-08

申请号：US09706322

申请日：2000-11-03

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： A61N1/32

CPC分类号： A61B5/6864 ,  A61B5/0031 ,  A61B5/0484 ,  A61B5/4094 ,  A61B5/7203 ,  A61N1/36064 ,  A61N1/36135

摘要： A system and method for determining and predicting a patient's susceptibility to neurological dysfunction based on measured electrophysiological parameters employs a self-contained implantable device with depth electrodes implanted in desired locations in the patient's brain. The patient's neurological tissue is stimulated to determine excitability and refractoriness (or inhibition period) parameters, which are employed to identify susceptibility to abnormal neurological activity, particularly epileptic seizures.

摘要翻译： 基于测量的电生理参数来确定和预测患者对神经功能障碍的敏感性的系统和方法使用具有植入患者大脑中期望位置的深度电极的独立可植入装置。 刺激患者的神经组织以确定兴奋性和耐受性（或抑制期）参数，其用于鉴定对异常神经活动的敏感性，特别是癫痫发作。

公开(公告)号：US06480743B1

公开(公告)日：2002-11-12

申请号：US09962940

申请日：2001-09-24

申请人： Bruce Kirkpatrick ,  Benjamin D. Pless

发明人： Bruce Kirkpatrick ,  Benjamin D. Pless

IPC分类号： A61N136

CPC分类号： A61N1/36135 ,  A61N1/36064 ,  A61N1/3615 ,  A61N1/36167

摘要： An implantable neurostimulator adapted to provide adaptive electrical brain stimulation includes a detection subsystem for isolating an electrographic signal characteristic and a stimulation system for applying an adaptive stimulation signal based at least in part upon the electrographic signal characteristic and correlated with the electrographic signal. Undesired learning of and acclimation to stimulation characteristics are avoided and stimulation efficacy is improved by adapting or otherwise varying the adaptive stimulation signal in relation to the electrographic signal.

摘要翻译： 适于提供自适应电脑刺激的可植入神经刺激器包括用于隔离电摄影信号特征的检测子系统和用于至少部分地基于电摄影信号特征并与电摄影信号相关联的施加自适应刺激信号的刺激系统。 避免对刺激特征的不期望的学习和适应，并且通过适应或以其它方式改变与电摄影信号相关的自适应刺激信号来提高刺激功效。

公开(公告)号：US06256535B1

公开(公告)日：2001-07-03

申请号：US09342796

申请日：1999-06-29

申请人： Rose Province ,  Benjamin D. Pless

发明人： Rose Province ,  Benjamin D. Pless

IPC分类号： A61N139

CPC分类号： A61N1/3925 ,  A61N1/3956

摘要： A method for delivering cardiac therapy, particularly defibrillation therapy, using an implantable cardioverter-defibrillator (ICD) or other cardiac therapy device. The method can be used either alone or in conjunction with any other suitable defibrillation (or other cardiac) therapy regimen. If used in conjunction with a conventional or other suitable defibrillation therapy regimen, the method can be considered to precondition the heart in advance of delivery of the defibrillation shock(s), in order to reduce the defibrillation threshold (DFT), and thus reduce the overall energy required for delivery of effective defibrillation therapy. In either case, in accordance with the method, the voltage gradients (VGs) across a plurality of different regions of the heart are sensed, e.g., using an endocardial sensor array (ESA), and a respective plurality of electrograms (EGMs) are produced in respective EGM channels. The excitable gaps (i.e., the intervals between successive activations) in the different VG regions of the heart are then brought into phase alignment with one another by appropriately timing the delivery of electrical stimulation (e.g., one or more pulses). In this connection, either the timing of the next activation interval can be advanced by delivering an electrical stimulus (pulse) during the excitable gap or in the late repolarization phase of the previous activation, or the activation interval can be extended by delivering an electrical stimulus earlier in the repolarization phase of the previous activation, leading to an extension of the refractory period (i.e., RPE). If three or more EGM channels are used, the excitable gaps in the different VG regions are preferably brought into phase with one another by first bringing the region associated with the near-field EGM channel into phase alignment with the region associated with the EGM channel of the adjacent (next highest) VG region and then successively entraining the thusly entrained regions with the regions associated with the EGM channels corresponding to the successively more distant VG regions, until the regions associated with all EGM channels are brought into phase alignment with one another. Also disclosed is a cardiac therapy device (e.g., an ICD) for implementing this method.

公开(公告)号：US5922215A

公开(公告)日：1999-07-13

申请号：US732651

申请日：1996-10-15

申请人： Benjamin D. Pless ,  William H. Elias ,  Sam Parler ,  J. Scott McCall

发明人： Benjamin D. Pless ,  William H. Elias ,  Sam Parler ,  J. Scott McCall

IPC分类号： A61N1/39 ,  H01G9/00 ,  B44C1/22 ,  C23F1/00

CPC分类号： H01G9/0029 ,  H01G9/00 ,  A61N1/3956

摘要： A method for making anode foil plates for use with layered electrolytic capacitors and capacitors made with such plates. A high purity aluminum foil is provided for generation of anode foil plates. Sheets of the foil are highly etched to provide a very high surface area. Following the etch process, the foil is partially cut or punched into plates from the etched sheets in the general shape of the finished capacitor housing with a portion remaining connected to the supporting foil. The supporting foil with the partially punched-out etched plates are subjected to a forming process by applying a voltage to the plates in the presence of an electrolyte to provide formed anode foil plates with edges which do not have to be reformed during capacitor aging and which do not have any particulates at cut edges. The formed anode plates are layered with cathode plates and separators in a capacitor housing with an electrolyte to provide a finished capacitor.

摘要翻译： 一种用于制造用这种板制成的层状电解电容器和电容器的阳极箔板的方法。 提供高纯度铝箔来生成阳极箔片。 箔的片被高度蚀刻以提供非常高的表面积。 在蚀刻工艺之后，将箔从被蚀刻的片材以完整的电容器壳体的大致形状部分地切割或冲压成板，其中一部分保持连接到支撑箔。 通过在电解质存在下向板上施加电压来对具有部分冲压蚀刻板的支撑箔进行成形处理，以在电容器老化期间提供具有不必重整的边缘的形成的阳极箔板，并且其中 在切割边缘没有任何颗粒物。 形成的阳极板与阴极板和分离器层叠在具有电解质的电容器壳体中以提供成品电容器。

公开(公告)号：US5763911A

公开(公告)日：1998-06-09

申请号：US658431

申请日：1996-06-05

申请人： M. Dean Matthews ,  Benjamin D. Pless

发明人： M. Dean Matthews ,  Benjamin D. Pless

IPC分类号： H01G2/16 ,  H01G2/14 ,  H01G4/30 ,  H01L27/108

CPC分类号： H01G2/14 ,  H01G4/306 ,  Y10S257/905 ,  Y10S257/908 ,  Y10S257/909

摘要： A capacitor optimized for use in an implantable medical device such as an implantable defibrillator is disclosed. In its simplest form, the capacitor comprises a thin planar dielectric sheet that has an array of cells open to one or both sides. Metallization is applied to the surface of the cells such that the walls of adjacent cells form a capacitor with the wall that separates the cells serving as the dielectric. The metallization pattern that forms the electrical connection to the cells may be patterned to limit the allowable current flow to each individual cell, thereby providing a fuse in the case of local dielectric failure.

摘要翻译： 公开了一种优化用于植入式除颤器的可植入医疗装置的电容器。 在其最简单的形式中，电容器包括薄平面电介质片，其具有向一侧或两侧敞开的单元阵列。 金属化被施加到电池的表面，使得相邻电池的壁与隔离用作电介质的电池的壁形成电容器。 形成与电池的电连接的金属化图案可以被图案化以限制到每个单独电池的容许电流，从而在局部电介质故障的情况下提供熔丝。

公开(公告)号：US5723969A

公开(公告)日：1998-03-03

申请号：US660259

申请日：1996-06-07

申请人： Stephen T. Archer ,  Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Stephen T. Archer ,  Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： H02J7/00 ,  H01M10/44 ,  H01M10/46

CPC分类号： H02J7/0093

摘要： A high voltage charger operates in a three-phase cycle. In a first phase, the high voltage charger operates at a fixed frequency. In a second phase, the high voltage charger operates at a variable frequency designed to draw a substantially constant average current from a power source. In the third phase, the high voltage charger returns to fixed frequency operation. The variable frequency is the reciprocal of the sum of an on-time and an off-time of the switch. In one embodiment, the on-time is provided by the time required for the switch to reach a predetermined maximum and the off-time is provided by the time over which a magnetic field in a transformer collapses.

摘要翻译： 高压充电器以三相循环工作。 在第一阶段，高压充电器以固定频率工作。 在第二阶段中，高压充电器以设计成从电源绘制基本恒定的平均电流的可变频率工作。 在第三阶段，高压充电器返回固定频率运行。 可变频率是开关的导通时间和关断时间之和的倒数。 在一个实施例中，导通时间由开关达到预定最大值所需的时间提供，并且关断时间由变压器中的磁场塌陷的时间提供。

公开(公告)号：US5456706A

公开(公告)日：1995-10-10

申请号：US177293

申请日：1994-01-04

申请人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

发明人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

IPC分类号： A61N1/05 ,  A61N1/39

CPC分类号： A61N1/0563 ,  A61N1/3956

摘要： A lead for use with an implantable cardioverter/defibrillator system is disclosed. In the preferred embodiment, the lead combines a right ventricular endocardial electrode, a superior vena cava electrode and one or more atrial sensing electrodes on a single catheter lead. The distal end of the lead is transvenously implanted, typically through an incision in the cephalic or subclavian vein. The proximal end of the lead is then tunneled below the fascia to the location of the pulse generator. Ventricular sensing and/or pacing electrode(s) may also be included at the distal end of the combined lead to provide ventricular intracardiac electrogram sensing and bradycardia pacing.

摘要翻译： 公开了一种用于植入式心律转复/除颤器系统的引导件。 在优选实施例中，引线将单个导管引线上的右心室心内膜电极，上腔静脉电极和一个或多个心房感测电极组合。 导管的远端经常植入，通常通过头部或锁骨下静脉中的切口。 引线的近端然后在筋膜下方隧道穿过脉冲发生器的位置。 心室感应和/或起搏电极也可以包括在组合导联的远端，以提供心室心电图检测和心动过缓起搏。

公开(公告)号：US5131388A

公开(公告)日：1992-07-21

申请号：US669646

申请日：1991-03-14

申请人： Benjamin D. Pless ,  William H. Elias ,  Timothy A. Marguit

发明人： Benjamin D. Pless ,  William H. Elias ,  Timothy A. Marguit

IPC分类号： A61N1/375 ,  A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/375

摘要： An implantable cardiac defibrillator is provided having an energy source, a capacitor, and means coupled to the energy source for charging the capacitor. The capacitor comprises a planar layered structure of anode plates, cathode plates and means separating the anode plates and cathode plates. A polymeric envelope containing electrolyte encloses the layered structure. Electrical contact means extend from the anodes and cathodes to outside the envelope.

公开(公告)号：US5014701A

公开(公告)日：1991-05-14

申请号：US354138

申请日：1989-05-19

申请人： Benjamin D. Pless ,  Kenneth J. Carroll

发明人： Benjamin D. Pless ,  Kenneth J. Carroll

IPC分类号： A61N1/39

CPC分类号： A61N1/3962

摘要： An implantable medical device includes electrodes coupled to a patient's heart and sensing circuitry having inputs connected to the electrodes for sensing cardiac electrical signals. The sensing circuitry includes a digital waveform analyzer system which performs direct analysis of digitized ECG heart signals from the atrial and/or ventricular channels. This eliminates the need for the system microprocessor to perform direct analysis on raw ECG data. The benefit being that complex software algorithms are not required, saving microprocessor memory space. System current drain is also reduced since the microprocessor need not be active during every ECG sample.

摘要翻译： 可植入医疗装置包括连接到患者心脏的电极和具有连接到电极的输入的感测电路，用于感测心脏电信号。 感测电路包括数字波形分析仪系统，其执行来自心房和/或心室通道的数字化ECG心脏信号的直接分析。 这样就无需系统微处理器对原始ECG数据进行直接分析。 好处是不需要复杂的软件算法，节省了微处理器的内存空间。 由于微处理器在每个ECG样本期间不需要有效，系统电流消耗也减少了。