公开(公告)号：US10779939B2

公开(公告)日：2020-09-22

申请号：US16637166

申请日：2018-08-07

Applicant: CARDIOVALVE LTD.

Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum

IPC: A61F2/24 ,  B23P15/00

Abstract: A unitary flexible sheet is folded to defines a panel, and first and second tabs. Each of the tabs has an inner layer and an outer layer. Commissural portions of prosthetic leaflets are sandwiched between inner layers of the first and second tabs. The tabs protrude from a first side of the panel, and are shaped such that progressively downstream parts of each tab protrude progressively further away from the panel portion. Other embodiments are also described.

公开(公告)号：US10537426B2

公开(公告)日：2020-01-21

申请号：US15668559

申请日：2017-08-03

Applicant: CARDIOVALVE LTD.

Inventor： Meni Iamberger ,  Aviram Baum ,  Boaz Harari ,  Ilia Hariton

IPC: A61F2/24 ,  A61F2/86 ,  A61F2/01

Abstract: A tubular valve body has an upstream end and a downstream end, and has a central longitudinal axis, and defines a lumen along the axis. Prosthetic leaflets are disposed within the lumen, and are configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction. The valve body has a cellular structure defined by a plurality of joists connected at nodes, the joists and nodes delimiting cells of the cellular structure. The nodes include minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected. The cells of the cellular structure comprise a first circumferential row of first-row cells. Each of the first-row cells is connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and is longitudinally delimited by two of the minor nodes. Other embodiments are described.

公开(公告)号：US10524910B2

公开(公告)日：2020-01-07

申请号：US15329920

申请日：2015-07-30

Applicant: CARDIOVALVE LTD.

Inventor： Tal Hammer ,  Meni Iamberger ,  Yaron Herman ,  Yuval Zipory ,  Eran Hoffer ,  Michael Albitov ,  Natalia Kruglova ,  Tal Reich ,  Ilia Hariton ,  Aviram Baum

IPC: A61F2/24 ,  A61F2/82

Abstract: A rod (508) is transfemorally advanceable to the heart. An implant (460) comprises (i) a first frame (462), compressed around a first longitudinal site of a distal portion of the rod, (ii) a second frame (464), compressed around a third longitudinal site of the distal portion, (iii) a valve member (50), disposed within the second frame, and (iv) a flexible sheet (466), coupling the first frame to the second frame, and disposed around a second longitudinal site of the distal portion, the second longitudinal site being between the first longitudinal site and the third longitudinal site. An extracorporeal controller (569) is coupled to a proximal portion of the rod, and is operably coupled to the distal portion of the rod. Operating the controller bends the distal portion of the rod causing articulation between the frames. Other embodiments are also described.