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56 条记录 (耗时 0.033 秒)

    Device for conditioning ex vivo pericardial tissue
    1.
    发明授权
    Device for conditioning ex vivo pericardial tissue 有权

    公开(公告)号：US12127757B2

    公开(公告)日：2024-10-29

    申请号：US17429446

    申请日：2019-12-23

    申请人： CARDIOVALVE LTD.

    发明人： Michael Albitov ,  Meni Iamberger ,  Ilia Hariton

    IPC分类号： A61B17/32

    CPC分类号： A61B17/32 ,  A61B2217/005 ,  A61B2560/0214 ,  A61B2560/0425

    摘要： Embodiments of the present disclosure include a method for conditioning ex vivo pericardial tissue that has a parietal side and a fibrous side from which fibers extend. A blade assembly includes a blade head having a blade array and a face that defines gaps therein. The parietal side of the tissue is placed downward against a support plate, and a motor is operated to move the blade array with respect to the face. The face contacts the tissue such that the fibers protrude through the gaps and into the blade head. The blade array shears the fibers that protrude through the gaps into the blade head, yielding sheared fibers. Other embodiments are also described.

    Prosthetic heart valve
    2.
    发明授权
    Prosthetic heart valve 有权

    公开(公告)号：US12029646B2

    公开(公告)日：2024-07-09

    申请号：US18216391

    申请日：2023-06-29

    申请人： CARDIOVALVE LTD.

    发明人： Ilia Hariton ,  Meni Iamberger ,  Boaz Harari ,  Aviram Baum

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/24 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2250/0003 ,  A61F2250/0039

    摘要： A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Each of the four sides of each of the four-sided closed cells is double-strutted. Other embodiments are also described.

    PROSTHETIC HEART VALVE
    5.
    发明公开
    PROSTHETIC HEART VALVE 审中-公开

    公开(公告)号：US20230390053A1

    公开(公告)日：2023-12-07

    申请号：US18234745

    申请日：2023-08-16

    申请人： CARDIOVALVE LTD.

    发明人： Ilia Hariton ,  Meni Iamberger ,  Boaz Harari ,  Aviram Baum

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/24 ,  A61F2220/0075 ,  A61F2/2427 ,  A61F2250/0039 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2/2436 ,  A61F2250/0003

    摘要： A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Exactly two of the four sides of each of the four-sided closed cells are double-strutted. Other embodiments are also described.

    Techniques for deployment of a prosthetic valve
    6.
    发明授权
    Techniques for deployment of a prosthetic valve 有权

    公开(公告)号：US11801135B2

    公开(公告)日：2023-10-31

    申请号：US17141853

    申请日：2021-01-05

    申请人： CARDIOVALVE LTD.

    发明人： Ilia Hariton ,  Boaz Harari ,  Maxim Karalnik ,  Meni Iamberger

    IPC分类号： A61F2/24 ,  A61F2/95 ,  A61F2/915

    CPC分类号： A61F2/2436 ,  A61F2/243 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/9517 ,  A61F2002/91575 ,  A61F2220/0016 ,  A61F2220/0025

    摘要： A method includes percutaneously advancing an implant to a native heart valve of a subject, the implant being housed in a compressed state within a delivery tool. Next, the method includes unhousing a longitudinally-intermediate portion of the implant, the longitudinally-intermediate portion being longitudinally between a longitudinally-proximal portion of the implant and a longitudinally distal portion of the implant. Subsequently, the longitudinally-proximal portion of the implant is unhoused. Subsequently, the longitudinally-distal portion of the implant is unhoused. By unhousing flanges of the implant, the flanges automatically expand. Upon the flanges expanding, a proximal end of each flange extends radially outward from a central longitudinal axis of the implant and longitudinally in a proximal direction. Other applications are also described.

    ANCHORING OF A PROSTHETIC VALVE
    8.
    发明申请
    ANCHORING OF A PROSTHETIC VALVE 有权

    公开(公告)号：US20220304804A1

    公开(公告)日：2022-09-29

    申请号：US17841912

    申请日：2022-06-16

    申请人： CARDIOVALVE LTD.

    发明人： Tal HAMMER ,  Meni Iamberger ,  Yaron Herman ,  Yuval Zipory ,  Eran Hoffer ,  Michael Albitov ,  Natalia Kruglova ,  Tal Reich ,  Ilia Hariton ,  Aviram Baum

    IPC分类号： A61F2/24

    摘要： A rod (508) is transfemorally advanceable to the heart. An implant (460) comprises (i) a first frame (462), compressed around a first longitudinal site of a distal portion of the rod, (ii) a second frame (464), compressed around a third longitudinal site of the distal portion, (iii) a valve member (50), disposed within the second frame, and (iv) a flexible sheet (466), coupling the first frame to the second frame, and disposed around a second longitudinal site of the distal portion, the second longitudinal site being between the first longitudinal site and the third longitudinal site. An extracorporeal controller (569) is coupled to a proximal portion of the rod, and is operably coupled to the distal portion of the rod. Operating the controller bends the distal portion of the rod causing articulation between the frames. Other embodiments are also described.

    Prosthetic valve with atrial tissue anchors having variable flexibility and ventricular tissue anchors having constant flexibility
    9.
    发明授权
    Prosthetic valve with atrial tissue anchors having variable flexibility and ventricular tissue anchors having constant flexibility 有权

    公开(公告)号：US11304806B2

    公开(公告)日：2022-04-19

    申请号：US16136082

    申请日：2018-09-19

    申请人： CARDIOVALVE LTD.

    发明人： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

    IPC分类号： A61F2/24

    摘要： Prosthetic valves and methods of implanting prosthetic valves may be provided, including an expandable prosthetic valve for implantation within a native heart valve. The prosthetic valve may include an annular valve body and atrial anchoring arms configured to extend radially outward from the annular valve body. Each atrial anchoring arm may have a proximal arm end and a distal arm end. The flexibility of at least one atrial anchoring arm may vary substantially from the proximal arm end thereof to the distal arm end thereof. The prosthetic valve may also include a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. Each ventricular anchoring leg may have a proximal leg end and a distal leg end. Each ventricular anchoring leg may have a substantially constant flexibility from the proximal leg end to the distal leg end.

    Prosthetic valve with connecting struts of variable size and tissue anchoring legs of variable size that extend from junctions
    10.
    发明授权
    Prosthetic valve with connecting struts of variable size and tissue anchoring legs of variable size that extend from junctions 有权

    公开(公告)号：US11304804B2

    公开(公告)日：2022-04-19

    申请号：US16135599

    申请日：2018-09-19

    申请人： CARDIOVALVE LTD.

    发明人： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

    IPC分类号： A61F2/24

    摘要： An expandable prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an expandable valve body having an atrial end, a ventricular end opposite the atrial end, and an intermediate portion extending between the atrial end and the ventricular end. The valve body may include a plurality of struts intersecting at junctions. The prosthetic valve may also include a plurality of tissue anchoring legs extending from junctions within the intermediate portion of the valve body. At least one of the tissue anchoring legs may have a cross-sectional area which is larger by at least 20% than a cross-sectional area of a strut extending between the at least one tissue anchoring leg and an adjacent tissue anchoring leg.