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公开(公告)号:US12023243B2
公开(公告)日:2024-07-02
申请号:US17010886
申请日:2020-09-03
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/243 , A61F2/2436 , A61F2/2445 , A61F2/2454 , A61F2/2463 , A61F2/2409 , A61F2/2418 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/007
Abstract: A prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an annular valve body. The prosthetic valve may also include a plurality of tissue anchors arranged about the valve body and configured to extend from connection points on the valve body. The prosthetic valve may also include at least one protective fabric covering extending over each of the connection points between each tissue anchor and the valve body.
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2.
公开(公告)号:US11318015B2
公开(公告)日:2022-05-03
申请号:US16135663
申请日:2018-09-19
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
Abstract: A prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an annular valve body, a plurality of atrial anchoring arms configured to extend radially outward from the annular valve body, and a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. The arms may be configured to engage an atrial portion of the native mitral valve and the ventricular anchoring legs may be configured to engage a ventricular portion of the native mitral valve. The atrial anchoring arms and the ventricular anchoring legs may be positioned relative to each other such that when the atrial anchoring arms and ventricular anchoring legs engage the native mitral valve, a volume between the atrial anchoring arms and ventricular anchoring legs is configured to be substantially filled with tissue.
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3.
公开(公告)号:US10856972B2
公开(公告)日:2020-12-08
申请号:US16136110
申请日:2018-09-19
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
Abstract: Prosthetic valves and methods of implanting prosthetic valves may be provided, including a prosthetic valve for implantation within a native heart valve. The prosthetic valve may include an annular valve body, a plurality of atrial anchoring arms, and a plurality of ventricular anchoring legs. The arms and legs may extend radially outward from the annular valve body and may each include a native valve tissue engaging portion. The arms may be angularly offset from the legs, with the tissue engaging portion of each arm and each leg arranged such that when the arms and legs are positioned on opposing sides of native heart valve tissue, the native heart valve tissue may assume a serpentine arrangement between the arms and the legs.
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公开(公告)号:US10575948B2
公开(公告)日:2020-03-03
申请号:US15956956
申请日:2018-04-19
Applicant: CARDIOVALVE LTD.
Inventor: Meni Iamberger , Aviram Baum , Ilia Hariton , Yelena Kasimov
Abstract: A frame assembly includes a valve body, a plurality of arms that each extend radially outward from the valve body to a respective arm-tip, and a plurality of ventricular legs that are coupled to the valve body and that extend radially outward from the valve body and toward the plurality of arms. A liner lines the lumen. Prosthetic leaflets are attached to the liner within the lumen. A first sheet of flexible material is attached to the plurality of arms. A second sheet of flexible material is attached to the first sheet and extends radially inwards and downstream, and is attached to the valve body. The first sheet, the second sheet, and the liner define an inflatable pouch therebetween. The apparatus defines a plurality of windows from the lumen into the pouch.
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5.
公开(公告)号:US20190083245A1
公开(公告)日:2019-03-21
申请号:US16135663
申请日:2018-09-19
Applicant: CARDIOVALVE LTD.
Inventor: Ilia HARITON , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
Abstract: A prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an annular valve body, a plurality of atrial anchoring arms configured to extend radially outward from the annular valve body, and a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. The arms may be configured to engage an atrial portion of the native mitral valve and the ventricular anchoring legs may be configured to engage a ventricular portion of the native mitral valve. The atrial anchoring arms and the ventricular anchoring legs may be positioned relative to each other such that when the atrial anchoring arms and ventricular anchoring legs engage the native mitral valve, a volume between the atrial anchoring arms and ventricular anchoring legs is configured to be substantially filled with tissue.
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公开(公告)号:US20190038404A1
公开(公告)日:2019-02-07
申请号:US15668559
申请日:2017-08-03
Applicant: CARDIOVALVE LTD.
Inventor: Meni Iamberger , Aviram Baum , Boaz Harari , Ilia Hariton
Abstract: A tubular valve body has an upstream end and a downstream end, and has a central longitudinal axis, and defines a lumen along the axis. Prosthetic leaflets are disposed within the lumen, and are configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction. The valve body has a cellular structure defined by a plurality of joists connected at nodes, the joists and nodes delimiting cells of the cellular structure. The nodes include minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected. The cells of the cellular structure comprise a first circumferential row of first-row cells. Each of the first-row cells is connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and is longitudinally delimited by two of the minor nodes. Other embodiments are described.
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公开(公告)号:US12029646B2
公开(公告)日:2024-07-09
申请号:US18216391
申请日:2023-06-29
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Boaz Harari , Aviram Baum
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/24 , A61F2/2427 , A61F2/2436 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2250/0003 , A61F2250/0039
Abstract: A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Each of the four sides of each of the four-sided closed cells is double-strutted. Other embodiments are also described.
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公开(公告)号:US11864996B2
公开(公告)日:2024-01-09
申请号:US17114771
申请日:2020-12-08
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/243 , A61F2/2436 , A61F2/2445 , A61F2/2454 , A61F2/2463 , A61F2/246 , A61F2/2409 , A61F2/2418 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2250/007
Abstract: An expandable prosthetic valve for implantation within a native heart valve may be provided. The prosthetic valve may include an expandable annular valve body. The valve body may include an atrial inlet opening and a ventricular outlet opening. The valve body may additionally include a plurality of tissue anchors extending from the valve body. The prosthetic valve may additionally include a flexible annular protective sleeve positioned about the rim of the valve body outlet opening and affixed to the outlet opening.
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公开(公告)号:US20230390053A1
公开(公告)日:2023-12-07
申请号:US18234745
申请日:2023-08-16
Applicant: CARDIOVALVE LTD.
Inventor: Ilia Hariton , Meni Iamberger , Boaz Harari , Aviram Baum
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/24 , A61F2220/0075 , A61F2/2427 , A61F2250/0039 , A61F2210/0014 , A61F2220/0008 , A61F2/2436 , A61F2250/0003
Abstract: A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Exactly two of the four sides of each of the four-sided closed cells are double-strutted. Other embodiments are also described.
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公开(公告)号:US20230190461A1
公开(公告)日:2023-06-22
申请号:US18109937
申请日:2023-02-15
Applicant: Cardiovalve Ltd.
Inventor: Ilia HARITON , Meni Iamberger , Aviram Baum , Boaz Harari
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/2454 , A61F2/2463 , A61F2/2445 , A61F2/2436 , A61F2/243 , A61F2/2409 , A61F2220/0008 , A61F2/246 , A61F2210/0014 , A61F2250/007 , A61F2/2466 , A61F2/2418
Abstract: An expandable prosthetic valve is implantable within a native mitral valve by terminal ends of ventricular anchors of the prosthetic valve moving outwardly from a constrained delivery position of the ventricular anchors, while the ventricular anchors are positioned within the atrium. Then, a portion of the expandable prosthetic valve containing the ventricular anchors is advanced through the native mitral valve into the ventricle. Terminal ends of atrial anchors of the prosthetic valve move outwardly relative to a portion of an annular valve body of the prosthetic valve while the atrial anchors are at least partially positioned within the atrium. Next, the annular valve body is radially expanded while the ventricular anchors are in the ventricle and the atrial anchors are in the atrium, thereby anchoring native heart valve tissue between the atrial anchors and ventricular anchors. Other embodiments are also described.
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